代表性论文
1. Junjie Meng, Hui He, Qianru Liu, Hanhong Xu, Huicai Huang*, Shao-Fei Ni*, Zhaodong Li*. Enantioselective Palladium(II)-Catalyzed Desymmetrizative Coupling of 7-Azabenzonorbornadienes with Alkynylanilines. Angew. Chem. Int. Ed. 2024, 63 e202315092. (中科院1区，Nature Index)
2. Huicai Huang, Swapna Konda, John C.-G. Zhao*. Diastereodivergent catalysis using modularly designed organocatalysts: Synthesis of both cis- and trans-fused pyrano[2,3-b]pyrane. Angew. Chem. Int. Ed. 2016, 55, 2213-2216. (中科院1区，Nature Index)
3. Huicai Huang, Zhichao Jin, Kailong Zhu, Xinmiao Liang, Jinxing Ye*. Highly diastereo-and enantioselective synthesis of 5-substituted 3-pyrrolidin-2-ones: Vinylogous Michael addition under multifunctional catalysis. Angew. Chem. Int. Ed. 2011, 50, 3232-3235. (中科院1区，Nature Index)
4. Shuzhong Wang, Chuyun Liang, Mingji Ke, Cuo Deji, Xinxin Wu*, Ruoting Zhan*, and Huicai Huang*. Photocatalytic Radical Decarboxylation [4 + 3] Annulation Reactions of Lactones via Dienoic Acid EDA Complexes. ACS Sustainable Chem. Eng. 2024, 12, 2531–2537.(中科院1区，highlighted by CBG NEWS)
5. Zheng Su, Binhong Tan, Zhaodong Li*, Huicai Huang*, and Yue Zhang*. Palladium/Amine Dual-Catalyzed Tsuji–Trost Fluoroallylation of Aldehydes with gem-Difluorinated Cyclopropanes. Org. Lett. 2024, 26, 5375–5379. (中科院1区，Nature Index)
6. Shuzhong Wang, Nuowen Zheng, Cuo Deji, Qingzhong Hu, Xinxin Wu, Ruoting Zhan*, Huicai Huang* and Yue Zhang*. Visible-Light-Promoted [4π + 2σ] Annulation of Dienes and Alkylamines via Dual Inert C(sp3)–H Bond Activation. Org. Lett. 2024, 26, 4705-4710. (中科院1区，Nature Index，highlighted by 邃瞳科学云)
7. Shuzhong Wang, Yili Zhang, Chuyun Liang, Yue Zhang, Ruoting Zhan and Huicai Huang*. Skeletal editing of chromone-fused dienes to cyclopropane by photochemical carbon deletion. Org. Lett. 2023, 25, 8269-8273. (中科院1区，Nature Index, highlighted by CBG NEWS )
8. Yue Zhang, Yili Zhang, Jian Lin, Zhaodong Li*, Huicai Huang*. Radical acylation: concepts, synthetic applications and directions. Org. Chem. Front. 2023, 10, 1056-1085. (中科院1区)
9. Yiming Du, Shuxin Chen, Hexiang Cao, Yichen Zhang, Hongtao Lei, Guoqin Xia*, Huicai Huang*, and Zhaodong Li*. Nickel-Catalyzed, Enantioselective Hydrofluoromethylation of Olefins: Access to Chiral α-Fluoromethylated Amides and Esters. Org. Lett. 2023, 25, 2218-2222. (中科院1区，Nature Index)
10. Yuzhen Chen, Yichen Wang, Shuzhong Wang, Yan-Yan Ma, Deng-Gao Zhao, Ruoting Zhan, Huicai Huang*. Asymmetric Construction of Cyclobutanes via Direct Vinylogous Michael Addition/Cyclization of β,γ-Unsaturated Amides. Org. Lett. 2020, 22, 7135-7140. (中科院1区，Nature Index, highlighted by CBG NEWS )
11. Yili Zhang, Xue Lu, Yichen Wang, Hui Xu, Ruoting Zhan, Weiwen Chen, Huicai Huang*. Regiodivergent Vinylogous−Cyclization Reactions of Cyclic α‑Amide Enone Acceptors: Synthesis of Highly Enantioenriched Heterobicyclic Structures. Org. Lett. 2019, 21, 10069-10074. (中科院1区，Nature Index, highlighted by CBG NEWS)
12. Jialiang Qin, Yili Zhang, Cuiting Liu, Jun Zhou, Ruoting Zhan, Weiwen Chen, Huicai Huang*. Asymmetric Inverse-Electron-Demand Diels–Alder Reaction of β,γ-Unsaturated Amides through Dienolate Catalysis. Org. Lett. 2019, 21, 7337-7341. (中科院1区，Nature Index)
13. Huicai Huang*, Xue Lu, Yukang Mao, Jinxing Ye*. Asymmetric synthesis of highly functionalized furanones via direct Michael reactions mediated by a bulky primary amine. Org. Chem. Front. 2019, 6, 1080-1083. (Outside front cover，中科院1区)
全部论文
44.Shuzhong Wang, Chuyun Liang, Mingji Ke, Cuo Deji, Xinxin Wu*, Ruoting Zhan*, and Huicai Huang*. Photocatalytic Radical Decarboxylation [4 + 3] Annulation Reactions of Lactones via Dienoic Acid EDA Complexes. ACS Sustainable Chem. Eng. 2024, 12, 7, 2531–2537.
43. Zheng Su, Binhong Tan, Zhaodong Li*, Huicai Huang*, and Yue Zhang*. Palladium/Amine Dual-Catalyzed Tsuji–Trost Fluoroallylation of Aldehydes with gem-Difluorinated Cyclopropanes. Org. Lett. 2024, 26, 5375–5379.
42. Shuzhong Wang, Nuowen Zheng, Cuo Deji, Qingzhong Hu, Xinxin Wu, Ruoting Zhan*, Huicai Huang* and Yue Zhang*. Visible-Light-Promoted [4π + 2σ] Annulation of Dienes and Alkylamines via Dual Inert C(sp3)–H Bond Activation. Org. Lett. 2024, 26, 4705-4710. (Nature Index)
41.Yuzhen Chen, Jiajia Chen, Lin Zhong, Yili Zhang, Ruoting Zhan, Huicai Huang* and Yongbo Xue*. Enantioselective synthesis of spirooxindole-pyran derivatives via a remote inverse-electron-demand Diels–Alder reaction of β,γ-unsaturated amides. Org. Biomol. Chem., 2024, 22, 3198-3203.
40. Junjie Meng, Hui He, Qianru Liu, Hanhong Xu, Huicai Huang*, Shao-Fei Ni*, Zhaodong Li*. Enantioselective Palladium(II)-Catalyzed Desymmetrizative Coupling of 7-Azabenzonorbornadienes with Alkynylanilines. Angew. Chem. Int. Ed., 2024, 63, e202315092.
39.Shuzhong Wang, Yili Zhang, Chuyun Liang, Yue Zhang, Ruoting Zhan and Huicai Huang*. Skeletal editing of chromone-fused dienes to cyclopropane by photochemical carbon deletion. Org. Lett. 2023, 25, 8269-8273.
38. Jialiang Qin, Mingji Ke, Cuo Deji, Shangping Xin, Yongbo Xue, Ruoting Zhan, Huicai Huang*. DBU-catalyzed Benzannulation towards Stilbene and Biaryl Derivatives from Acyclic Amides with Methyl Coumalate. European Journal of Organic Chemistry, 2024, e202300711.
37. Yiming Du, Shuxin Chen, Hexiang Cao, Yichen Zhang, Hongtao Lei, Guoqin Xia*, Huicai Huang*, and Zhaodong Li*. Nickel-Catalyzed, Enantioselective Hydrofluoromethylation of Olefins: Access to Chiral α-Fluoromethylated Amides and Esters. Org. Lett. 2023, 25, 2218-2222.
36. Yue Zhang, Yili Zhang, Jian Lin, Zhaodong Li*, Huicai Huang*. Radical acylation: concepts, synthetic applications and directions. Org. Chem. Front., 2023, 10, 1056-1085.
35. Xiurong Zheng, Jiajia Chen, Zhuowen Li, Lin Zhong, Ruoting Zhan, Huicai Huang*. Organocatalytic oxa-Michael/Michael Addition/Deformylation Cascade Reaction of 3-Formylchromone with p-Quinol: Synthesis of the Furanochromanone Skeleton. Adv. Synth. Catal. 2022, 364, 4402-4408.
34. Shangping Xing, Feifei Nong,Yaqin Wang, Da Huang, Jialiang Qin, Yu-Fei Chen, Dan-Hua He, Pei-En Wu, Huicai Huang, Ruoting Zhan, Hui Xu, Yong-Qiang Liu*. Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis. Pharmacological Research 2022, 106059.
33. Yangqing Zheng, Weichao Jiang, Jingbo Tan, Juzhang Yan, Ruoting Zhan, Huicai Huang*. Organocatalytic β,γ-Selective Activation of Deconjugated Butenolides Access to Chiral Tricyclic Chroman-butyrolactones. J. Org. Chem. 2021, 86, 12821-12830.
32. Juzhang Yan, Xiurong Zheng, Yangqing Zheng, Ruoting Zhan, Huicai Huang*. Asymmetric Michael reaction of 3-homoacyl coumarins ith chromone-fused dienes toward enantioenriched coumarin chromone skeletons. Org. Biomol. Chem. 2021, 19, 8102-8107.
31. Shangping Xing, Feifei Nong, Jialiang Qin, Huicai Huang, Ruoting Zhan, Weiwen Chen*. Gentiopicroside Produces Endothelium-Independent Vasodilation by Deactivating the PI3K/Akt/Rho-Kinase Pathway in Isolated Rat Thoracic Aorta. BioMed Research International 2021, 5565748.
30. Juzhang Yan, Xiaoping Li, Yuzhen Chen, Ying Li, Weiwen Chen, Ruoting Zhan, Huicai Huang*. Organocatalytic 1,4-Addition of Azadienes with 3-Homoacyl Coumarins toward Highly Enantioenriched Benzofuran Coumarin Skeletons. J. Org. Chem. 2020, 85, 12175-12186.
29. Yuzhen Chen, Yichen Wang, Shuzhong Wang, Yan-Yan Ma, Deng-Gao Zhao, Ruoting Zhan, Huicai Huang*. Asymmetric Construction of Cyclobutanes via Direct Vinylogous Michael Addition/Cyclization of β,γ-Unsaturated Amides. Org. Lett. 2020, 22, 7135-7140. (highlighted by CBG NEWS )
28. Yili Zhang, Xue Lu, Yichen Wang, Hui Xu, Ruoting Zhan, Weiwen Chen, Huicai Huang*. Regiodivergent Vinylogous−Cyclization Reactions of Cyclic α‑Amide Enone Acceptors: Synthesis of Highly Enantioenriched Heterobicyclic Structures. Org. Lett. 2019, 21, 10069-10074. (highlighted by CBG NEWS)
27. Jialiang Qin, Yili Zhang, Cuiting Liu, Jun Zhou, Ruoting Zhan, Weiwen Chen, Huicai Huang*. Asymmetric Inverse-Electron-Demand Diels–Alder Reaction of β,γ-Unsaturated Amides through Dienolate Catalysis. Org. Lett. 2019, 21, 7337-7341.
26. Xiaoping Li, Juzhang Yan, Jialiang Qin, Shilin Lin, Weiwen Chen, Ruoting Zhan, Huicai Huang*. Enantioselective Synthesis of Benzofuran-Fused N-Heterocycles via Chiral Squaramide Catalyzed [4+2] Cyclization of Azadienes with Azlactones. J. Org. Chem. 2019, 84, 8035-8045.
25. Xue Lu#, Yili Zhang#, Yichen Wang, Yuzhen Chen, Weiwen Chen, Ruoting Zhan, John Zhao, Huicai Huang*. Asymmetric Catalysis Using Modularly Designed Organocatalysts: Synthesis of Fused Tricyclic Pyrano-Pyrano[2,3-c]pyrrol Derivatives. Adv. Synth. Catal. 2019, 361, 3234-3238.
24. Yichen Wang, Yuzhen Chen, Xiaoping Li, Yukang Mao, Weiwen Chen, Ruoting Zhan, Huicai Huang*. Enantioselective synthesis of pyrano [2,3-c]pyrrole via an organocatalytic [4+2] cyclization reaction of dioxopyrrolidines and azlactones. Org. Biomol. Chem. 2019, 17, 3945-3950.
23. Huicai Huang*, Xue Lu, Yukang Mao, Jinxing Ye*. Asymmetric synthesis of highly functionalized furanones via direct Michael reactions mediated by a bulky primary amine. Org. Chem. Front. 2019, 6, 1080-1083. (Outside front cover)
22. Yukang Mao, Yili Zhang, Zheng Luo, Ruoting Zhan, Hui Xu, Weiwen Chen*, Huicai Huang*. Synthesis, Biological Evaluation and Low-Toxic Formulation Development of Glycosylated Paclitaxel Prodrugs. Molecules 2018, 23, 3211.
Before @GZUCM
21. Diastereodivergent catalysis using modularly designed organocatalysts: Synthesis of both cis- and trans-fused pyrano[2,3-b]pyrane.
Huicai Huang, Swapna Konda, John C.-G. Zhao*.
Angew. Chem. Int. Ed. 2016, 55, 2213-2216.
20. Stereoselective synthesis of spirooxindole derivatives using an organocatalyzed tandem Michael-Michael reaction.
Huicai Huang, Manisha Bihani, John C.-G. Zhao*.
Org. Biomol. Chem. 2016, 14, 1755-1763.
19. Asymmetric β-alkylation of aldehydes through an organocatalyzed C-C bond scission reaction.
Huicai Huang, Santhi Abbaraju, John C.-G. Zhao*.
Synlett 2016, 27, 1379-1382.
18. Highly diastereo- and enantioselective cross-cascade reactions of different Enones.
Huicai Huang, Wenbin Wu, Kailong Zhu, Juan Hu, Jinxing Ye*.
Chem. Eur. J. 2013, 19, 3838-3841.
17. Highly diastereoselective and enantioselective Michael addition of 5 H-oxazol-4-ones to α, β-unsaturated ketones catalyzed by a new bifunctional organocatalyst with broad substrate scope and applicability.
Huicai Huang, Kailong Zhu, Wenbin Wu, Zhichao Jin, Jinxing Ye*.
Chem. Commun. 2012, 48, 461-463.
16. Highly diastereo-and enantioselective synthesis of 5-substituted 3-pyrrolidin-2-ones: Vinylogous Michael addition under multifunctional catalysis.
Huicai Huang, Zhichao Jin, Kailong Zhu, Xinmiao Liang, Jinxing Ye*.
Angew. Chem. Int. Ed. 2011, 50, 3232-3235.
15. Asymmetric vinylogous Michael reaction of α, β-unsaturated ketones with γ-butenolide under multifunctional catalysis.
Huicai Huang, Feng Yu, Zhichao Jin, Wenjun Li, Wenbin Wu, Xinmiao Liang, Jinxing Ye*.
Chem. Commun. 2010, 46, 5957-5959.
14. Organocatalyzed asymmetric aldol reactions of ketones and β,γ-unsaturated α-ketoesters and phenylglyoxal hydrates.
Swapna Konda, Qun-Sheng Guo, Manabu Abe, Huicai Huang, Hadi Arman, and John C.-G. Zhao*.
J. Org. Chem. 2015, 80, 806-815.
13. A metal–organic framework as a highly efficient and reusable catalyst for the solvent-free 1, 3-dipolar cycloaddition of organic azides to alkynes.
Peng Li, Sridhar Regati, Huicai Huang, Hadi D Arman, John C-G Zhao, Banglin Chen*.
Inorganic Chemistry Frontiers 2015, 2, 42-46
12. A sulfonate-based Cu (I) metal-organic framework as a highly efficient and reusable catalyst for the synthesis of propargylamines under solvent-free conditions.
Peng Li, Sridhar Regati, Huicai Huang, Hadi D Arman, Banglin Chen, John C-G Zhao*.
Chin. Chem. Lett. 2015, 26, 6-10
11. Highly diastereodivergent synthesis of tetrasubstituted cyclohexanes catalyzed by modularly designed organocatalysts.
Nirmal K Rana, Huicai Huang, John Cong-Gui Zhao*.
Angew. Chem. Int. Ed. 2014, 53, 7749-7753.
10. Asymmetric intramolecular oxa-Michael reactions of cyclohexadienones catalyzed by a primary amine salt.
Wenbin Wu, Xin Li, Huicai Huang, Xiaoqian Yuan, Junzhu Lu, Kailong Zhu, Jinxing Ye*.
Angew. Chem. Int. Ed. 2013, 52, 1743-1747.
9. Highly stereoselective synthesis of trisubstituted cyclohexanols using a guanidine-catalyzed tandem Henry–Michael reaction.
Qipu Dai, Huicai Huang, John Cong-Gui Zhao*.
J. Org. Chem. 2013, 78, 4153–4157.
8. Aminocatalyzed asymmetric Diels–Alder reaction of 2, 4-dienals and rhodanine/hydantoin derivatives.
Kailong Zhu, Huicai Huang, Wenbin Wu, Yuan Wei, Jinxing Ye*.
Chem. Commun. 2013, 49, 2157-2159.
7. Asymmetric construction of spirocyclohexanonerhodanines catalyzed by simple diamine derived from chiral tert-leucine.
Wenbin Wu, Huicai Huang, Xiaoqian Yuan, Kailong Zhu, Jinxing Ye*.
Chem. Commun. 2012, 48, 9180-9182.
6. Diastereo-and enantioselective synthesis of oxazine and oxazolidine derivatives with a chiral quaternary carbon center under multifunctional catalysis.
Zhichao Jin, Xiao Wang, Huicai Huang, Xinmiao Liang, Jinxing Ye*.
Org. Lett. 2011, 13, 564-567.
5. Enantioselective organocatalytic synthesis of oxazolidine derivatives through a one-pot cascade reaction.
Zhichao Jin, Huicai Huang, Wenjun Li, Xiaoyan Luo, Xinmiao Liang, Jinxing Ye*.
Adv. Synth. Catal. 2011, 353, 343-348.
4. Diastereoselective synthesis of bicyclo [2.2.2] octan-2-one derivatives through an unexpected organocatalytic tandem Michael-Michael reaction.
Juanjuan Yang, Huicai Huang, Zhichao Jin, Wenbin Wu, Jinxing Ye*.
Synthesis 2011, 12, 1984-1987.
3. Catalytic asymmetric Michael addition with curcumin derivative.
Wenjun Li, Wenbin Wu, Feng Yu, Huicai Huang, Xinmiao Liang, Jinxing Ye*.
Org. Biomol. Chem. 2011, 9, 2505-2511.
2. A one-pot asymmetric organocatalytic tandem reaction for the synthesis of oxazine derivatives.
Zhichao Jin, Feng Yu, Xiao Wang, Huicai Huang, Xiaoyan Luo, Xinmiao Liang, Jinxing Ye*
Org. Biomol. Chem. 2011, 9, 1809-1816.
1. A highly efficient asymmetric Michael addition of α, α-disubstituted aldehydes to maleimides catalyzed by primary amine thiourea salt.
Feng Yu, Zhichao Jin, Huicai Huang, Tingting Ye, Xinmiao Liang, Jinxing Ye*
Org. Biomol. Chem. 2010, 8, 4767-4774.