还涛博士目前已在综合或专业领域内权威期刊(Nature Methods, Nature Protocols, Analytical Chemistry)等发表论文近 40 篇,引用1200余次。详见Google Scholar:https://scholar.google.ca/citations?user=n30snbsAAAAJ&hl=en
2020
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- T. Oh; S. Kim, C. Caussy, T. Fu; J. Guo; S. Bassirian, S. Singh, E. Madamba, R. Bettencourt, L, Richards, M. Raffatellu, P. Dorrestein, R. Yu, A. Atkins, T Huan, D. Brenner, C. Sirlin, R. Knight, R. Loomba, ‘A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis’, Cell Metabolism, accepted, 2020
- A. Palermo, T. Huan, D. Rinehart, MM. Rinschen, S. Li, V. B. O’Donnell, E. Fahy, J. Xue, S. Subramaniam, HP. Benton, G. Siuzdak, ‘Cloud‐based archived metabolomics data: A resource for in‐source fragmentation/annotation, meta‐analysis and systems biology’, Analytical Science Advances, accepted, 2020
- D. Chen, W. Han, T. Huan; L. Li, L. Li, ‘Effects of Freeze-Thaw Cycles of Blood Samples on High-Coverage Quantitative Metabolomics’, Analytical Chemistry, accepted, 2020
- J. Guo, T. Huan, ‘Comparison of Full-Scan, Data-Dependent, and Data-Independent Acquisition Modes in Liquid Chromatography-Mass Spectrometry Based Untargeted Metabolomics’, Analytical Chemistry, accepted, 2020
- H. Yu, S. Xing, L. Nierves, P. Lange, T. Huan, ‘Fold-Change Compression: An Unexplored But Correctable Quantitative Bias Caused by Nonlinear Electrospray Ionization Responses in Untargeted Metabolomics‘, Analytical Chemistry, 92(10), 7011-7019, 2020
- Cirstea, AC. Yu, E. Golz, K. Sundvick, D. Kliger, N. Radisavljevic, LH. Foulger, M. Mackenzie, T. Huan, BB. Finlay, S. Appel-Cresswell, ‘Microbiota Composition and Metabolism are Associated with Gut Function in Parkinson’s Disease’, Movement Disorders, accepted, 2020
- Y. Dong, AA. Arif, J. Guo, Z. Ha, S. Lee-Sayer, G. Poon, M. Dosanjh, C. Roskelley, T. Huan, P. Johnson, ‘CD44 Loss Disrupts Lung Lipid Surfactant Homeostasis and Exacerbates Oxidized Lipid-Induced Lung Inflammation’, Frontiers in Immunology, 11, 29, 2020
2019
- X. Tang, Y. Kudo, J. Baker, S. LaBonte, P. Jordan, S. McKinne, J. Guo, T. Huan, B. Morre, A. Edlund, ‘Cariogenic Steptococcus Produces Tetramic Acid Strain-Specific Antibiotics That Impair Commensal Colonization’, ACS Infectious Diseases, 6(4), 563-571, 2019
- L. Li, X. Zheng, Q. Zhou, N. Villanueva, W. Nian, X. Liu, T. Huan, ‘Metabolomics-Based Discovery of Molecular Signatures for Triple Negative Breast Cancer in Asian Female Population’, Scientific Reports, 10(1), 1-12, 2019 (Reported in Nature Research Cancer Community)
- J. Yang, Y. Han, C.H. Mah, E. Wanjaya, B. Peng, T. Xu, M. Liu, T. Huan, M. Fang, ‘Streamlined MRM method transfer between instruments assisted with HRMS matching and Retention-time prediction’, Analytica Chimca Acta, 1100, 88-96, 2019
- Y. Hu, B. Cai, T. Huan, ‘Enhancing metabolome coverage in data-dependent LC-MS/MS analysis through an integrated feature extraction strategy’, Analytical Chemistry, 91(22), 14433-14441, 2019
- J.J. Zhang, X. Tang, T. Huan, A.C. Ross, B.S. Morre, ‘Pass-Back Chain Extension Expands Multi-Modular Assembly Line Biosynthesis’, Nature Chemical Biology, 16, 42-49, 2019
- RC. Gimple, RL. Kidwell, L. J.Y. Kim, T. Sun, A. D. Gromovsky, Q. Wu, M. Wolf, D. Lv, S. Bhargava, L. Jiang, B. C. Prager, X. Wang, Q. Ye, Z. Zhu, G. Zhang, Z. Dong, L. Zhao, D. Lee, J. Bi, A. E. Sloan, P. S. Mischel, J. M. Brown, H. Cang, T. Huan, S. C. Mack, Q. Xie, J. N. Rich, ‘Glioma Stem Cell Specific Super Enhancer Promotes Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling’, Cancer Discovery, 9(9), 1248-1267, 2019
- S. Jia, T. Xu. T. Huan, M. Chong, M. Liu, W. Fang, M. Fang, ‘Chemical Isotope Labeling Exposome (CIL-EXPOSOME): One High-Throughput Platform for Human Urinary Global Exposome Characterization’, Environmental Science & Technology, 53(9), 5445-5453, 2019
Pre-UBC Publications
2018
- T. Huan, T. Tran, J. Zheng, S. Sapkota, S.W. MacDonald, R. Camicioli, R. Dixon, L. Li, ‘Metabolomics Analyses of Saliva Detect Novel Biomarers of Alzheimer’s Disease’, Journal of Alzheimer’s Disease, 65, 1401-1416, 2018
- T. Huan, A. Palermo, J. Ivanisevic, D. Rinehart, D. Edler, T. Phommavongsay, HP. Benton, C. Guijas, X. Domingo-Almenara, B. Warth, G. Siuzdak, ‘Autonomous Multi-Modal Metabolomics Data Integration for Comprehensive Pathway Analysis’, Analytical Chemistry, 90(14), 8396-8403, 2018
- S. Sapkota, T. Huan, T. Tran, J. Zheng, R. Camicioli, L. Li, R. Dixon, ‘Alzheimer’s Biomarkers from Multiple Modalities Selectively Discriminate Clinical Status: Relative Importance of Salivary Metabolomics Panels, Genetic, Lifestyle, Cognitive, Functional Health, and Demographic Risk Markers’. Frontiers in Aging Neuroscience, 10, 296, 2018
- C. Guijas, JO. Montenegro-Burke, X. Dominogo-Almenara, A. Palermo, B. Warth, G. Hermann, G. Koellensperger, T. Huan, W. Uritboonthai, A. Aisporna, D. Wolan, M. Spiker, HP. Benton, G. Siuzdak, ‘METLIN: a Technology Platform for Identifying Knows and Unknowns’, Analytical Chemistry, 5(90), 3156-3164, 2018
- B. Warth, A. Granados, T. Huan, M. Fang, E. Forsberg, P. Benton, L. Goetz, CH. Johnson, G. Gary, ‘Dietary Xenoestrogens Strongly Alters the Cellular Metabolic Response of Palbociclib/Letrozole Combination Therapy’, Cell Chemical Biology, 25(3), 291-300, 2018
- CC. Lee, YJ. Hsieh, SW. Chen, SH. Fu, CW. Hsu, CC. Wu, W. Han, Y. Li, T. Huan, YS. Chang, JS. Yu, L. Li, CH. Chang, YT. Chen, ‘Bretschneider Solution-Induced Alterations in the Urine Metabolome in Cardiac Surgery Patients’, Scientific Reports, 8, 17774, 2018
2017
- T. Huan, E. Forsberg, D. Rinehart, CH. Johnson, J. Ivanisevic, HP. Benton, M. Fang, A. Aisporna, B. Hilmers, FL. Poole, MP. Thorgersen, MWW. Adams, G. Krantz, MW. Field, PD. Robbins, LJ. Niedernhofer, T. Ideker, EL. Majumder, JD. Wall, NJW. Rattray, R. Goodacre, LL. Larison, G. Siuzdak, ‘Systems Biology Guided by XCMS Online Metabolomics’, Nature Methods, 14(5), 461-462, 2017
- E. Forsberg, T. Huan, D. Rinehart, H. Benton, B. Hilmers, G. Siuzdak, ‘Metabolic Pathway Mapping and Multi-omic Analysis using XCMS Online’, Nature Protocols, 13(4), 633-651, 2017
- B. Warth, S. Spangler, M. Fang, C. Johnson, E. Forsberg, R. Martin, A. Granados, X. Domingo-Almenara, T. Huan, D. Rinehart, J. Montenegro-Burke, B. Hilmers, A. Aisporna, L. Hoang, W. Heim, P. Benton, S. Richardson, S. Spangler, A. Williams, G. Siuzdak, ‘Exposome-Scale Investigations Guided by Global Metabolomics, Pathway Analysis, and Cognitive Computing’, Analytical Chemistry, 89(21), 11505-11513, 2017
2016
- JR Montenegor-Burke, AE. Aisporna, HP. Benton, D. Rinehart, M. Fang, T. Huan, B. Warth, EM. Forsberg, BT. Abe, J. Ivanisevic, L. Teyton, L. Lairson, G. Siuzdak, ‘Data Streaming for Metabolomics: Accelerating Data Processing and Analysis from Days to Minutes’, Analytical Chemistry, 89(2), 1254, 2016
- JR Montenegor-Burke, T. Phommavongsay, AE. Aisporna, T. Huan, D.Rinehart, E. Forsberg, FL. Poole, MP. Thorgersen, MWW. Adams, G. Krantz, MW. Fields, TR. Northen, PD. Robbins, LJ. Niedemhofer, L. Lairson, HP. Benton, G. Siuzdak, ‘Smartphone Analytics: Mobilizing the Lab into the Cloud for Omic-Scale Analyses’, Analytical Chemistry, 88 (19), 2016
- T. Huan, JW. Xia, WN. Leung, L. Li, CW. Chan, ‘Cerebrospinal Fluid Metabolomics After Natural Product Treatment in an Experimental Model of Cerebral Ischemia’, OMICS: A Journal of Integrative Biology, 20(11), 670-680, 2016
- T. Huan, DA. Troyer, L. Li, ‘Metabolite Analysis and Histology on the Exact Same Tissue: Comprehensive Metabolomics Profiling and Metabolic Classification of Prostate Cancer’, Scientific Reports, 6, 2016
- X. Luo, S. Zhao, T. Huan, D. Sun, RMN. Friis, MC. Schultz, L. Li, ‘High-Performance Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry for Profiling the Metabolomic Reprogramming Elicited by Ammonium Limitation in Yeast’, Journal of Proteome Research, 15(5) 1602-1612, 2016
- S. Geng, C. Zhou, W. Chen, S. Yu, W. Huang, T. Huan, J. Xu, X. Yan, ‘Fatty Acid and Sterol Composition Reveal Food Selectivity of Juvenile Ark Shell Tegillarca Granosa Linnaeus after Feeding with Mixed Microalgae’, Aquaculture, 455 109-117, 2016
- X. Su, N. Wang, D. Chen, Y. Li, Y. Lu, T. Huan, W. Xu, L. Li, L. Li, ‘Dansylation Isotope Labeling Liquid Chromatography Mass Spectrometry for Parallel Profiling of Human Urinary and Fecal Submetabolomes’, Analytical Chimica Acta, 903 100-109, 2016
2015
- T. Huan, Y. Wu, C. Tang, G. Lin, L. Li, ‘DnsID in MyCompoundID for Rapid Identification of Dnsylated Amine- and Phenol-containing Metabolites in Metabolomics’. Analytical Chemistry, 87(19) 9838-9845, 2015
- T. Huan, C. Tang, R. Li, Y. Shi, G. Lin, L. Li, ‘MyCompoundID MS/MS search: Metabolite Identification Using a Library of Predicted Fragment-Ion-Spectra of 383,830 Possible Human Metabolites’. Analytical Chemistry, 87(20) 10619-10626, 2015
- T. Huan, L. Li, ‘Quantitative Metabolome Analysis Based on Chromatographic Peak Reconstruction in Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry’, Analytical Chemistry, 87(14) 7011-7016, 2015
- R. Zhou, T. Huan, L. Li, ‘Development of Versatile Isotopic Labelling Reagents for Profiling the Amine Submetabolome by Liquid Chromatography Mass Spectrometry’, Analytical Chimica Acta, 881 107-116, 2015
- T. Huan, L. Li, ‘Counting Missing Values in Metabolome Dataset for Measuring the Analytical Performance of a Metabolomics Platform’, Analytical Chemistry, 87(2) 1306-1313. 2015
2014
- W. Xu, D. Chen, X. Su, N. Wang, R. Zhou,T. Huan, Q. Xie, L. Li, L. Li, ‘Development of High-Performance Chemical Isotope Labeling LC-MS for Profiling the Human Fecal Metabolome’, Analytical Chemistry, 87(2) 829-836. (ACS Editor Choice Paper), 2014
- R. Zhou, CL. Tseng, T. Huan, L. Li, ‘IsoMS: Automated Processing of LC-MS Data Generated by a Chemical Isotope Labeling Metabolomics Platform’, Analytical Chemistry, 86(10) 4675-4679, 2014
- RMN. Friis, JP. Glaves, T. Huan, L. Li, BD. Sykes, MC. Schultz, ‘Rewiring AMPK and mitochondrial retrograde signaling for metabolic control of aging and histone acetylation in respiratory-defective cells’, Cell Reports, 7(2) 565-574, 2014
2013
- L. Li, R. Li, J. Zhou, A. Zuniga, AE. Stanislaus, Y. Wu, T. Huan, J. Zheng, Y. Shi, DS. Wishart, G. Lin, ‘MyCompoundID: Using an Evidence-based Metabolome Library for Metabolite Identification’, Analytical Chemistry, 85(6) 3401-3408, 2013