代表作:
21)Lulu Zhang#, Yanrong Wang#, Siqi Zhang#, Xingkai Wang, Jieting Shen, Lin Xie, Yiding Zhang, Hailong Zhang, Kuan Hu*, Feng Wang*, Rui Wang*, Ming-Rong Zhang*, Linear peptide-based PET tracers for imaging PD-L1 in tumors, Molecular Pharmaceutics, 20, 4256-4267, (2023) .
20) Lin Xie#; Lulu Zhang#; Kuan Hu#; Masayuki Hanyu; Yiding Zhang; Masayuki Fujinaga; Katsuyuki Minegishi; Takayuki Ohkubo; Kotaro Nagatsu; Cuiping Jiang; Takashi Shimokawa; Noriyuki Okonogi; Shigeru Yamada; Feng Wang; Rui Wang; Ming-Rong Zhang. Alpha-radiopharmaceutical 211At-AITM reduces mGluR1 and induces senescence to elicit long-lasting antitumor efficacy. Cell Reports Medicine, 4, 100960, (2023).
19)Duo Wang#, Chan Feng#, Zeyu Xiao#,*, Cuiqing Huang, Zerong Chen, Weiming Fang, Xiaocong Ma, Xingkai Wang, Liangping Luo*, Kuan Hu*, Wei Tao*. Therapeutic hydrogel for enhanced immunotherapy: A powerful combination of MnO2 nanosheets and vascular disruption. Nano Today 47, 101673, (2022) https://doi.org/10.1016/j.nantod.2022.101673
18) Dongyuan Wang*, Yuan Tian, Yu Zhang, Xiaona Sun, Yuxuan Wu, Ruping Liu, Fang Zeng, Jingjing Du & Kuan Hu*. An assembly-inducing PDC enabling the efficient nuclear delivery of nucleic acid for cancer stem-like cell suppression. Nanoscale 14, 15384-15392, (2022) doi:10.1039/D2NR02118H.
17) Juan Sun#, Zhenyuan Huangfu#, Jiangtao Yang, Guanglin Wang*, Kuan Hu*, Mingyuan Gao & Zhiyuan Zhong*. Imaging-guided targeted radionuclide tumor therapy: From concept to clinical translation. Advanced Drug Delivery Reviews 190, 114538, (2022) doi:https://doi.org/10.1016/j.addr.2022.114538.
16) Zeyu Xiao#, Duo Wang#, Chan Wang#, Zerong Chen, Cuiqing Huang, Yuan Yang, Lin Xie, Lulu Zhang, Lingling Xu, Ming-Rong Zhang*, Kuan Hu*, Zhou Li* & Liangping Luo*. PEIGel: A biocompatible and injectable scaffold with innate immune adjuvanticity for synergized local immunotherapy. Materials Today Bio, 100297, (2022) doi:https://doi.org/10.1016/j.mtbio.2022.100297.
15) Lin Xie#, Kuan Hu#, Yanhong Duo#, Takashi Shimokawa, Katsushi Kumata, Yiding Zhang, Cuiping Jiang, Lulu Zhang, Nobuki Nengaki, Hidekatsu Wakizaka, Yihai Cao* & Ming-Rong Zhang*. Off-tumor IDO1 target engagements determine the cancer-immune set point and predict the immunotherapeutic efficacy. Journal for ImmunoTherapy of Cancer 9, e002616, (2021) doi:10.1136/jitc-2021-002616. (Highlighted by EurekAlert AAAS, MedicalXPress, The Medical News, ScienMag, sciencenewsnet.in, MedicalTribune, Jano, True Viral News, Tii生命科学)
14) Tong Li, Xian-Mao Lu, Ming-Rong Zhang, Kuan Hu* & Zhou Li*. Peptide-based nanomaterials: Self-assembly, properties and applications. Bioactive Materials 11, 268-282, (2021). https://doi.org/10.1016/j.bioactmat.2021.09.029. (ESI highly cited paper)
13) Kuan Hu#, Wenyu Wu#, Lin Xie, Hao Geng, Yiding Zhang, Masayuki Hanyu, Lulu Zhang, Yinghuan Liu, Kotaro Nagatsu, Hisashi Suzuki, Jialin Guo, Yundong Wu*, Zigang Li*, Feng Wang* & Mingrong Zhang*. Whole-body PET tracking of a D-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors. Acta Pharmaceutica Sinica B 12, 1363-1376, (2021) doi:https://doi.org/10.1016/j.apsb.2021.09.016. (入选“2021年深圳湾实验室最受关注科研进展top10")
12) Chan Wang#, Kuan Hu#, Chaochao Zhao, Yang Zou, Ying Liu, Xuecheng Qu, Dongjie Jiang, Zhe Li, Ming-Rong Zhang & Zhou Li. Customization of Conductive Elastomer Based on PVA/PEI for Stretchable Sensors. Small 16, 1904758, (2020) doi:10.1002/smll.201904758. (Featured as Back cover; Highlighted by MaterialsViews)
11) Kuan Hu, Zhimin Yang#, Lingling Zhang#, Lin Xie, Lu Wang, Hao Xu, Lee Josephson, Steven H. Liang & Ming-Rong Zhang. Boron agents for neutron capture therapy. Coordination Chemistry Reviews 405, 213139, (2020) doi:https://doi.org/10.1016/j.ccr.2019.213139.
10) Kuan Hu, Wei Xiong, Chengjie Sun, Chan Wang, Jingxu Li, Feng Yin, Yixiang Jiang, Ming-Rong Zhang, Zhou Li*, Xinwei Wang* & Zigang Li*. Self-Assembly of Constrained Cyclic Peptides Controlled by Ring Size. CCS Chemistry 2, 42-51, (2020). https://doi.org/10.31635/ccschem.020.201900047.
9) Kuan Hu, Lin Xie, Yiding Zhang, Masayuki Hanyu, Zhimin Yang, Kotaro Nagatsu, Hisashi Suzuki, Jiang Ouyang, Xiaoyuan Ji, Junjie Wei, Hao Xu, Omid C. Farokhzad, Steven H. Liang*, Lu Wang*, Wei Tao* & Ming-Rong Zhang*. Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy. Nature communications 11, 2778, (2020) doi:10.1038/s41467-020-16513-0. (ESI highly cited paper, Highlighted by QLifePro, QST news, OPTRONICS, PHOTONICS, )
8) Kuan Hu, Lin Xie, Masayuki Hanyu, Yiding Zhang, Lingyun Li, Xiaohui Ma, Kotaro Nagatsu, Hisashi Suzuki, Weizhi Wang* & Ming-Rong Zhang*. Harnessing the PD-L1 interface peptide for positron emission tomography imaging of the PD-1 immune checkpoint. RSC Chemical Biology 1, 214-224, (2020) doi:10.1039/D0CB00070A. (Featured as Front cover, Highlighted by RSC Chemical Biology Editors' Choice and The Chemical Biology of Peptides )
7) Kuan Hu, Hanyu Masayuki, Lin Xie, Yiding Zhang, Nagatsu Kotaro, Suzuki Hisashi & Ming-Rong Zhang. Developing native peptide-based radiotracers for PD-L1 PET imaging and improving imaging contrast by pegylation. Chemical Communications 55, 4162-4165, (2019) doi:10.1039/C9CC00445A. (Featured as back inside cover)
6) Kuan Hu#, Feng Yin#, Ziyuan Zhou#, Chenshan Lian, Yinghuan Liu, Chengjie Sun, Wenjun Li, Jianing Zhang & Zigang Li. Directional assembly of a stapled α-helical peptide. Chemical Communications 55, 10484-10487, (2019) doi:10.1039/C9CC04591K.
5) Huaying Wang#, Kuan Hu#, Zhe Li#, Chan Wang, Min Yu, Zigang Li* & Zhou Li*. Black Phosphorus Nanosheets Passivation Using a Tripeptide. Small 14, 1801701, (2018) doi:doi:10.1002/smll.201801701.
4) Kuan Hu#, Yixiang Jiang#, Wei Xiong, Hu Li, Pei-Yu Zhang, Feng Yin, Qianling Zhang, Hao Geng, Fan Jiang*, Zhou Li*, Xinwei Wang* & Zigang Li*. Tuning peptide self-assembly by an in-tether chiral center. Science Advances 4, eaar5907, (2018) doi:10.1126/sciadv.aar5907. (Highlighted by PKU News, X-MOL, 中科院之声,and BioArt)
3) Kuan Hu#, Feng Yin#, Mengyin Yu, Chengjie Sun, Jingxu Li, Yujie Liang, Wenjun Li, Mingsheng Xie, Yuanzhi Lao, Wei Liang* & Zi-gang Li*. In-Tether Chiral Center Induced Helical Peptide Modulators Target p53-MDM2/MDMX and Inhibit Tumor Growth in Stem-Like Cancer Cell. Theranostics 7, 4566-4576, (2017) doi:10.7150/thno.19840. (Featured as Front cover)
2) Kuan Hu#, Chengjie Sun#, Dan Yang, Yujie Wu, Chuan Shi, Longjian Chen, Tao Liao, Jialin Guo, Yinghuan Liu & Zigang Li. A precisely positioned chiral center in an i, i + 7 tether modulates the helicity of the backbone peptide. Chemical Communications 53, 6728-6731, (2017) doi:10.1039/C7CC03799F.
1) Kuan Hu, Hao Geng, Qingzhou Zhang, Qisong Liu, Mingsheng Xie, Chengjie Sun, Wenjun Li, Huacan Lin, Fan Jiang, Tao Wang*, Yun-Dong Wu* & Zigang Li*. An In-tether Chiral Center Modulates the Helicity, Cell Permeability, and Target Binding Affinity of a Peptide. Angewandte Chemie International Edition 55, 8013-8017, (2016) doi:10.1002/anie.201602806. (Highlighted by PKU News and X-MOL)