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成果及论文


(19) Yuan Xue, Si-Hua Hou*Xiang Zhang, Fu-Min Zhang, Xiao-Ming Zhang, Yong-Qiang Tu*

Total Synthesis of the Hexacyclic Sesterterpenoid Niduterpenoid B via Structural Reorganization Strategy.

J. Am. Chem. Soc. 2024146, 25445−25450

Most Read Articles in September and October, 2024


 (18) Jun-Jie Yin, Yun-Peng Wang, Jun Xue, Feng-Fan Zhou, Xing-Qian Shan, Rong Zhu, Kun Fang, Lei Shi*, Shu-Yu Zhang, Si-Hua Hou*, Wujiong Xia, and Yong-Qiang Tu*

Total Syntheses of Polycyclic Diterpenes Phomopsene, Methyl Phomopsenonate, and iso-Phomopsene via Reorganization of C–C Single Bonds.

J. Am. Chem. Soc. 2023145, 21170-21175

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Highlight by Synfacts 2023, 19(11), 1065.

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(17) Si-Hua Hou,# Xuan Yu,# Rui Zhang, Cole Wagner, Guangbin Dong,* 

Rhodium-Catalyzed Diastereo- and Enantioselective Divergent Annulations between Cyclobutanones and 1,5-Enynes: Rapid Construction of Complex C(sp3)‑Rich Scaffolds.

J. Am. Chem. Soc. 2022144, 22159 – 22169. (# contributed equally).

(16) Quan-Zhe Li,# Si-Hua Hou,# Jin-Chen Kang, Peng-Fei Lian, Yu Hao, Chao Chen, Jia Zhou, Tong-Mei Ding, Shu-Yu Zhang*.

 Bioinspired Palladium-Catalyzed Intramolecular C(sp3)H Activation for the Collective Synthesis of Proline Natural Products.

Angew. Chem. Int. Ed. 202261, e202207088(# contributed equally).


Prior to SJTU

(15) Si-Hua Hou, Adriana Y. Prichina, Guangbin Dong,* 

Deconstructive Asymmetric Total Synthesis of Morphine-Family Alkaloid (–)-Thebainone A.

Angew. Chem. Int. Ed. 202160, 13057 – 13064.

(14) Si-Hua Hou, Xuan Yu, Rui Zhang, Lin Deng, Mengxi Zhang, Adriana Y. Prichina, Guangbin Dong,* 

Enantioselective Intramolecular Type II-Cycloaddition of Alkynes via CC Activation of Cyclobutanones: Rapid and Asymmetric Construction of [3.3.1] Bridged Bicycles.

J. Am. Chem. Soc. 2020142, 13180-13189.

(13) Si-Hua Hou, Adriana Y. Prichina, Mengxi Zhang, Guangbin Dong,*

Asymmetric Total Syntheses of Di- and Sesqui-Terpenoids via Catalytic C–C Activation of Cyclopentanones.

Angew. Chem. Int. Ed. 202059, 7848 – 7856.

(12) Wei Jiang, Jia Zhou, Ai-Jun Ma, Dongli Li, Yanyan Ma, Deng-Gao Zhao, Si-Hua Hou, Jun-Bing Lin, Shu-Yu Zhang*, 

Dienamine-Mediated Deconjugative Addition/Cyclization Cascade of γ, γ-Disubstituted Enals with Carboxylic Acid-Activated Enones: A Rapid Access to Highly Functionalized γ-Lactones.

Org. Chem. Front.20207, 571 – 577.

(11) Quan-Zhe Li, Xun-Hui Wang, Si-Hua Hou, Yan-Yan Ma, Deng-Gao Zhao, Shu-Yu Zhang*, He-Yuan Bai, Tong-Mei Ding, 

Silver-Catalyzed para-Selective C–H Amination of 1-Naphthylamides with Azodicarboxylates at Room Temperature.

Synthesis201951, 2697 – 2704.

(10) Jia Zhou, Guo-Dong Zhu, Le Wang, Fu-Xin Tan, Wei Jiang, Zhi-Gang Ma, Jun-Chen Kang, Si-Hua Hou, Shu-Yu Zhang*, 

Remote C6-Enantioselective C–H Functionalization of 2, 3-Disubstituted Indoles through the Dual H-Bonds and π–π Interaction Strategy Enabled by CPAs.

Org. Lett. 201921, 8662 – 8666.

(9) Le Wang, Jia Zhou, Tong-Mei Ding, Zhi-Qiang Yan, Si-Hua Hou, Guo-Dong Zhu, Shu-Yu Zhang*, 

Asymmetric N-Hydroxyalkylation of Indoles with Ethyl Glyoxalates Catalyzed by a Chiral Phosphoric Acid: Highly Enantioselective Synthesis of Chiral N,O-Aminal Indole Derivatives.

Org. Lett. 201921, 2795 – 2799.

(8) Lin Liu, Hai-Long Cheng, Wen-Qiang Ma, Si-Hua Hou, Yong-Qiang Tu*, Fu-Min Zhang, Xiao-Ming Zhang, Shao-Hua Wang.

Improved synthesis of 8-oxabicyclo [3.2. 1] octanes via tandem C–H oxidation/oxa-[3, 3] Cope rearrangement/aldol cyclization.

Chem. Comm. 201854, 196 – 199.

(7) Ting-Yu Zhang, Jun-Bing Lin, Quan-Zhe Li, Jun-Chen Kang, Jin-Long Pan, Si-Hua Hou, Chao Chen, Shu-Yu Zhang*, 

Copper-Catalyzed Selective ortho-C–H/N–H Annulation of Benzamides with Arynes: Synthesis of Phenanthridinone Alkaloids.

Org. Lett. 201719, 1764 – 1767.

(6) Jin-Long Pan, Quan-Zhe Li, Ting-Yu Zhang, Si-Hua Hou, Jun-Cheng Kang, Shu-Yu Zhang*, 

Palladium-catalyzed direct intermolecular silylation of remote unactivated C (sp 3)–H bonds.

Chem. Comm. 2016, 52, 13151-13154.

(5) Si-Hua Hou, Yong-Qiang Tu,* Shuang-Hu Wang, Chao-Chao Xi, Fu-Min Zhang, Shao-Hua Wang, Yan-Tao Li, Lin Liu, 

Total Syntheses of the Tetracyclic Cyclopiane Diterpenes Conidiogenone, Conidiogenol, and Conidiogenone B.

Angew. Chem. Int. Ed. 201655, 4456 – 4460.

(4) Si-Hua Hou, Yong-Qiang Tu,* Lin Liu, Fu-Min Zhang, Shao-Hua Wang,* Xiao-Ming Zhang, 

Divergent and Efficient Syntheses of the Lycopodium Alkaloids (–)-Lycojaponicumin C, (–)-8-Deoxyserratinine, (+)-Fawcettimine, and (+)-Fawcettidine.

Angew. Chem. Int. Ed. 201352, 11373 –11376. 

(3) Fu-Min Zhang, Lei Peng, Hui Li, Ai-Jun Ma, Jin-Bao Peng, Jing-Jing Guo, Dengtao Yang, Si-Hua Hou, Yong-Qiang Tu,* William Kitching, 

Total Synthesis of the Nominal Didemnaketal A.

Angew. Chem. Int. Ed. 201251, 10846 –10850.

(2) Ai-Jun Ma, Yong-Qiang Tu,* Jin-Bao Peng, Qing-Yun Dou, Si-Hua Hou, Fu-Min Zhang, Shao-Hua Wang, 

Total Synthesis of (-)-FR901483.

Org. Lett. 201214, 3604-3607.

(1) Dong Wang, Jihui Li, Na Li, Tingting Gao, Sihua Hou, Baohua Chen*, 

An efficient approach to homocoupling of terminal alkynes: Solvent-free synthesis of 1, 3-diynes using catalytic Cu (II) and base.

Green Chem. 201012, 45 – 48.