2024

128     Chemiluminescence immunoassay amplified by functional acridinium ester for the detection of NT-proBNP in clinical samples

          Fugang Li, Qiang Li, Xiaoqiang Shi, Yongxi Zhao, Zhiqian Guo

          Dyes and Pigments，Volume 230, 2024, 112353, ISSN 0143-7208, https://doi.org/10.1016/j.dyepig.2024.112353.

127    Ultra-high signal-to-noise ratio near-infrared chemiluminescent probe for in vivo sensing singlet oxygen

         Meiling Zhao, Yao Lu, Yutao Zhang, Haoyun Xue, Zhiqian Guo

            Chinese Chemical Letters, 2024, 110105, ISSN 1001-8417, https://doi.org/10.1016/j.cclet.2024.110105.

126   Organic functional dyes

          Zhi-Qian Guo, Wei-Hong Zhu, Jiangli Fan, Jong Seung Kim,

          Green Chemical Engineering, Volume 4, Issue 4,2023,Pages 377-378,ISSN 2666-9528,

          https://doi.org/10.1016/j.gce.2023.05.002.

125   Sequence-activated chemiluminescence probes: programmable illumination for high-contrast in vivo sensing and imaging

         Yutao Zhang, Juan Li, Wei-Hong Zhu & Zhiqian Guo

         Sci. China Chem. (2024). https://doi.org/10.1007/s11426-024-2143-0

124   “Crossbreeding” NIR-II flavchromene for PSMA-positive prostate cancer detection and image-guided surgery

          Jialiang Huang, Yongkang Yao, Liao Zhang, Chenxu Yan, Zhiqian Guo

          Smart Molecules, p. e20240020, https://doi.org/10.1002/smo.20240020.

123    A de novo zwitterionic strategy of ultra-stable chemiluminescent probes: highly selective sensing of singlet oxygen in FDA-approved phototherapy

          Yao Lu,   Yutao Zhang,   Xia Wu,   Ruihua Pu,   Chenxu Yan,   Weimin Liu,   Xiaogang Liu,   Zhiqian Guo  and  Weihong Zhu    

          Chem. Sci., 2024, DOI: 10.1039/D4SC01915F

122     Engineering high-performance dicyanomethylene-4H-pyran fluorophores for biosensing and phototherapy

           Qiang Liu, Chuyang Sun, Ruilong Dai, Chenxu Yan, Yutao Zhang, Wei-Hong Zhu, Zhiqian Guo

           Coord Chem Rev, 2024, 503, 215652.

121     Engineering Near-Infrared Fluorescent Probes Based on Modulation of Molecular Excited States

           Chenxu Yan, Zhirong Zhu, Yongkang Yao, Qi Wang, Zhiqian Guo, and Wei-Hong Zhu*

           Accounts of Materials Research 2024 5 (1), 64-75 DOI: 10.1021/accountsmr.3c00196

2023

120     Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast in vivo bioimaging

          Liao Zhang, Chenxu Yan, Yutao Zhang, Dun Ma, Jialiang Huang, Zijun Zhao, Yining Tao, Caiqi Liu, Juan Li, Wei-Hong Zhu and                        Zhiqian Guo

          Chem. Commun., 2023,59, 8388-8391

119     Uniting Dual-Modal MRI/ChemiluminescenceNanotheranostics: Spatially and Sensitively Self-ReportingPhotodynamic Therapy in Oral Cancer

           Yining Tao, Chenxu Yan, Yue Wu, Dan Li, Juan Li, Yuchen Xie, Yingsheng Cheng, Yisheng Xu, Kai Yang, Wei-Hong Zhu, and Zhiqian Guo

118     A Reversible Dual-Channel Near-Infrared Flavonoid Probeforin VivoTracking Glutathione Dynamics in Living Mice

           Zijun Zhao, Yutao Zhang, Menglan Wu, Chenxu Yan, and Zhiqian Guo

117     Restriction of intramolecular bending (RIB) enables the quantitative design of AIEgens；

          Weijie Chi, Jianfeng Dai, Chengxu Yan, Davin Tan, Zhiqian Guo and Xiaogang Liu

116     A Mitochondrial-targeted curcumin-based fluorescent probe for real-time tracking endogenous hydrogen peroxide in living cells

           Mingming Zhu a, Ting Wang, Yutao Zhang, Jiahuan Nong, Zhiqian Guo

115     Bent-to-planar Si-rhodamines: a distinct rehybridization lights up NIR-II fluorescence for tracking nitric oxide in the Alzheimer's disease brain

           Qingshuang Xu, Yutao Zhang, Mingming Zhu, Chenxu Yan, Wenle Mao, Wei-Hong Zhu and Zhiqian Guo*

114     Preparation of near-infrared AIEgen-active fluorescent probes for mapping amyloid-β plaques in brain tissues and living mice

           Chenxu Yan, Jianfeng Dai Yongkang Yao, Wei Fu, He Tian, Wei-Hong Zhu, and Zhiqian Guo*

 

2022

112      A “crossbreeding” dyad strategy for bright and small-molecular weight near-infrared fluorogens: From the structural design to                  boost aggregation-induced emission

          Juan Li, Meiling Zhao, Jialiang Huang, Pengqi Liu, Xinyu Luo, Yutao Zhang, Chenxu Yan, Wei-Hong Zhu, and Zhiqian Guo*

110   “Crossbreeding” Small-Molecular Weight NIR-II Flavchromenes Endows Activatable Multiplexed In Vivo Imaging

           Liao Zhang, Yutao Zhang, Weijie Chi, Chenxu Yan, Zijun Zhao, Xiaogang Liu, Wei-Hong Zhu, and Zhiqian Guo*
           ACS Mater. Lett., 2022, 4 (8), 1493–1502.

109    Water-soluble bright NIR AIEgens with hybrid ROS for wash-free mitochondrial“off–on”imaging and photodynamic therapy

 Fang-Zhou Xu, Cheng-Yun Wang*, Qi Wang, Jian-Wei Zou, Yi-Jie Qiao, Zhi-Qian Guo, Weijun Zhao* and Wei-Hong Zhu*
 Chem. Commun., 2022, 58 (44), 6393-6396.

108    Rational design of shortwave infrared (SWIR) fluorescence probe: Cooperation of ICT and ESIPT processes for sensing endogenous                   cysteine

          Maoju Chang, Chenxu Yan*, Lei Shi, Dan Li, Wei Fu and Zhiqian Guo*

          Chin. Chem. Lett., 2022, 33 (2), 762-766.

107    Sequence-Activated Fluorescent Nanotheranostics for Real-Time Profiling Pancreatic Cancer

 Yining Tao, Chenxu Yan, Dan Li, Jianfeng Dai, Yingsheng Cheng, Hui Li*, Wei-Hong Zhu, and Zhiqian Guo*
 JACS Au, 2022, 2 (1), 246–257.

2021

106   Circularly Polarized Fluorescence Resonance Energy Transfer (C‐FRET) for Efficient Chirality Transmission within an Intermolecular                    System

Yue Wu, Chenxu Yan, Xin-Shun Li, Li Hong You, Zhen-Qiang Yu*, Xiaofeng Wu, Zhigang Zheng, Guofeng Liu, Zhiqian Guo, He Tian, and Wei-Hong Zhu*
Angew. Chem. Int. Ed., 2021, 60 (46), 24549-24557.

105    NAD(+) supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-                            infiltrated T cells

Yuetong Wang, Fei Wang, Lihua Wang, Shizhen Qiu, Yufeng Yao, Chenxu Yan, Xuexue Xiong, Xuyong Chen, Quanquan Ji, Jian Cao, Ganglong Gao, Dake Li, Liye Zhang, Zhiqian Guo, Ruoning Wang, Haopeng Wang*, and Gaofeng Fan*
Cell Rep., 2021, 36 (6), 109516.

104    Enzyme-activatable fluorescent probes for β-galactosidase: from design to biological applications

Yongkang Yao, Yutao Zhang, Chenxu Yan, Wei-Hong Zhu and Zhiqian Guo*
Chem. Sci., 2021, 12 (29), 9885-9894.

 

103    Harnessing α- l -fucosidase for in vivo cellular senescence imaging

Seyoung Koo, Miae Won, Hao Li, Won Young Kim, Mingle Li, Chenxu Yan, Amit Sharma, Zhiqian Guo *, Wei-Hong Zhu*, Jonathan L. Sessler*, Jin Yong Lee* and Jong Seung Kim*
Chem. Sci., 2021, 12 (29), 10054-10062.

102   Engineering Nanoparticulate Organic Photocatalysts via a Scalable Flash Nanoprecipitation Process for Efficient Hydrogen                            Production

Miaojie Yu, Weiwei Zhang, Zhiqian Guo, Yongzhen Wu* and Weihong Zhu*
Angew. Chem. Int. Ed., 2021, 60 (28), 15590-15597.

 

101    Fluorescence umpolung enables light-up sensing of N-acetyltransferases and nerve agents

Chenxu Yan, Zhiqian Guo, Weijie Chi, Wei Fu, Syed Ali Abbas Abedi, Xiaogang Liu, He Tian and Wei-Hong Zhu*
Nat. Commun., 2021, 12 (1), 3869.

 

100    Photoresponsive aggregation-induced emission polymer film for anti-counterfeiting

Hong Yang, Mengqi Li, Weijun Zhao*, Zhiqian Guo and Wei-Hong Zhu
Chin. Chem. Lett., 2021, 32 (12), 3882-3885.

 

99      A turn-on fluorescent probe based on π-extended coumarin for imaging endogenous hydrogen peroxide in RAW 264.7 cells

Yu-Bo Wang, Hui-Zhen Luo, Cheng-Yun Wang*, Zhi-Qian Guo, and Wei-Hong Zhu*
Journal of Photochemistry and Photobiology a-Chemistry, 2021, 414, 113270.

98      Tracking Ultrafast Structural Dynamics in a Dual-Emission Anti-Kasha-Active Fluorophore Using Femtosecond Stimulated Raman                  Spectroscopy

Jingle Wei, Yuexia Wu, Ruihua Pu, Limin Shi, Jiaming Jiang, Juan Du, Zhiqian Guo*, Yifan Huang*, and Weimin Liu*
J. Phys. Chem. Lett., 2021, 12 (18), 4466-4473.

97      pH‐activated polymeric profragrances for dual‐controllable perfume release

Ming Liu, Chenxu Yan, Jianwei Han, Zhiqian Guo, Zuobing Xiao, Yue Wu, Jian Huang , and Wei-Hong Zhu*
AlChE J., 2021, 67 (8), e17265.

96      Harnessing Hypoxia‐Dependent Cyanine Photocages for In Vivo Precision Drug Release

Yutao Zhang, Chenxu Yan, Qiaoqiao Zheng, Qian Jia, Zhongliang Wang, Ping Shi, Zhiqian Guo*

Angew. Chem. Int. Ed., 2021, 60 (17), 9553-9561.

95      Engineering molecular self-assembly of theranostic nanoprobes for dual-modal imaging-guided precise chemotherapy

Chenxu Yan, Hongxia Xu, Menglan Wu, Zijun Zhao, Weijun Zhao, Jianbin Tang, and Zhiqian Guo*
Sci. China Chem., 2021, 64 (11), 2045-2052.

94      Rational Design of Near-Infrared Cyanine-Based Fluorescent Probes for Rapid In Vivo Sensing Cysteine

Hehe Zhang, Chenxu Yan, Hui Li, Lei Shi, Ruofei Wang, Zhiqian Guo*, and Wei-Hong Zhu

ACS Appl. Bio Mater., 2021, 4 (3), 2001–2008.

93      Recent progress on molecularly near-infrared fluorescent probes for chemotherapy and phototherapy

Chenxu Yan, Yutao Zhang, and Zhiqian Guo*
Coord. Chem. Rev., 2021, 427, 213556.

 

2020

92      De novo strategy with engineering anti-Kasha/Kasha fluorophores enables reliable ratiometric quantification of biomolecules

Limin Shi, Chenxu Yan, Zhiqian Guo*, Weijie Chi, Jingle Wei, Weimin Liu, Xiaogang Liu*, He Tian and Wei-Hong Zhu*

Nat. Commun., 2020, 11 (1).

91      Spatio-Temporally Reporting Dose-Dependent Chemotherapy via Uniting Dual-Modal MRI/NIR Imaging

Yiyu Ma, Chenxu Yan, Zhiqian Guo*,Guang Tan, Dechao Niu, Yongsheng Li, and Wei-Hong Zhu

Angew. Chem. Int. Ed., 2020, 59 (47), 21143-21150.

 

90      High-Performance Quinoline-Malononitrile Core as a Building Block for the Diversity-Oriented Synthesis of AIEgens

Zhiqian Guo, Chenxu Yan, and Wei-Hong Zhu*

Angew. Chem. Int. Ed., 2020, 59 (25), 9812-9825.

 

89      A Sequential Dual-Lock Strategy for Photoactivatable Chemiluminescent Probes Enabling Bright Duplex Optical Imaging

Yutao Zhang, Chenxu Yan, Chao Wang, Zhiqian Guo*, Xiaogang Liu, and Wei-Hong Zhu

Angew. Chem. Int. Ed., 2020, 59 (23), 9059-9066.

 

88      In vivo real-time tracking of tumor-specific biocatalysis in cascade nanotheranostics enables synergistic cancer treatment

Ruofei Wang, Chenxu Yan, Hehe Zhang, Zhiqian Guo* , and Wei-Hong Zhu

Chem. Sci., 2020, 11 (12), 3371-3377.

 

87      Rational Design of Ratiometric Near-Infrared Aza-BODIPY-Based Fluorescent Probe for in Vivo Imaging of Endogenous Hydrogen                Peroxide

Wenle Mao, Mingming Zhu, Chenxu Yan, Yiyu Ma, Zhiqian Guo*, and Weihong Zhu

          ACS Appl. Bio Mater., 2020, 3 (1), 45–52.

 

2019

86      Photocontrollable Release with Coumarin-Based Profragrances

Ming Liu, Jianwei Han*, Chenxu Yan, Zhiqian Guo, Zuobing Xiao, and Wei-Hong Zhu*

ACS Appl. Bio Mater., 2019, 2 (9), 4002–4009.

85      A molecular design strategy toward enzyme-activated probes with near-infrared I and II fluorescence for targeted cancer imaging

Rongchen Wang, Jian Chen, Jie Gao, Ji-An Chen, Ge Xu, Tianli Zhu, Xianfeng Gu, Zhiqian Guo, Wei-Hong Zhu , and Chunchang Zhao*

Chem. Sci., 2019, 10 (30), 7222-7227.

 

84      Fluorescence Imaging of Alzheimer's Disease with a Flat Ensemble Formed between a Quinoline-Malononitrile AIEgen and Thin-                  Layer Molybdenum Disulfide

Weitao Dou, Jingjing Zhang, Qiang Li, Zhiqian Guo, Wei-Hong Zhu, Guorong Chen, Haiyan Zhang*, and Xiaopeng He*

ChemBioChem, 2019, 20 (14), 1856-1860.

 

83      POSS: A Morphology-Tuning Strategy To Improve the Sensitivity and Responsiveness of Dissolved Oxygen Sensor

Shuwen Wang, Kaizhi Gu, Chenxu Yan, Zhiqian Guo*, Ping Zhao, and Wei-Hong Zhu*

Industrial & Engineering Chemistry Research, 2019, 58 (19), 7761-7768.

 

82      Near-Infrared Aggregation-Induced Emission-Active Probe Enables in situ and Long-Term Tracking of Endogenous beta-                              Galactosidase Activity

Wei Fu, Chenxu Yan, Yutao Zhang, Yiyu Ma, Zhiqian Guo*, and Wei-Hong Zhu

Front. Chem., 2019, 7.

 

81      An ultrasensitive fluorescent probe for hydrazine detection and its application in water samples and living cells

ShaoHua Guo, ZhiQian Guo, ChengYun Wang*, Yongjia Shen, and Wei-HongZhu*

Tetrahedron, 2019, 75 (18), 2642-2646.

 

80      High-Fidelity Trapping of Spatial-Temporal Mitochondria with Rational Design of Aggregation-Induced Emission Probes

Jie Zhang, Qi Wang, Zhiqian Guo*, Shaoze Zhang, Chenxu Yan, He Tian, and Wei-Hong Zhu*

Adv. Funct. Mater., 2019, 29 (16).

 

79      Broadening AIEgen application: rapid and portable sensing of foodstuff hazards in deep-frying oil

Yue Wu, Pengwei Jin, Kaizhi Gu, Chuanxin Shi, Zhiqian Guo, Zhen-Qiang Yu* and Wei-Hong Zhu*

Chem. Commun., 2019, 55 (28), 4087-4090.

 

78      Nanomized tumor-microenvironment-active NIR fluorescent prodrug for ensuring synchronous occurrences of drug release and                  fluorescence tracing

Qiang Li, Jun Cao, Qi Wang*, Jie Zhang, Shiqin Zhu, Zhiqian Guo , and Wei-Hong Zhu*

J. Mater. Chem. B, 2019, 7 (9), 1503-1509.

 

77      Activatable near-infrared emission-guided on-demand administration of photodynamic anticancer therapy with a theranostic                      nanoprobe

Rongchen Wang, Kaikai Dong, Ge Xu, Ben Shi, Tianli Zhu, Ping Shi*, Zhiqian Guo, Wei-Hong Zhu , and Chunchang Zhao*

Chem. Sci., 2019, 10 (9), 2785-2790.

 

76      Ratiometric and light-up near-infrared fluorescent DCM-based probe for real-time monitoring endogenous tyrosinase activity

Qiang Li, Chenxu Yan, Jie Zhang, Zhiqian Guo*, and Wei-Hong Zhu

Dyes Pigm., 2019, 162, 802-807.

 

75      Rational Design of Near-Infrared Aggregation-Induced-Emission Active Probes: In Situ Mapping of Annyloid-beta Plaques with                    Ultrasensitivity and High-Fidelity

Wei Fu, Chenxu Yan, Zhiqian Guo*, Jingjing Zhang, Haiyan Zhang*, He Tian, and Wei-Hong Zhu*

J. Am. Chem. Soc., 2019, 141 (7), 3171-3177.

 

74     Saponin-Based Near-Infrared Nanoparticles with Aggregation-Induced Emission Behavior: Enhancing Cell Compatibility and                         Permeability

         Jie Zhang, Qi Wang, Jingkang Liu, Zhiqian Guo*, Jinfeng Yang, Qiang Li, Shaoze Zhang, Chenxu Yan, and Wei-Hong Zhu*

         ACS Appl. Bio Mater., 2019, 2 (2), 943–951.

 

73      A FRET-based dual-channel turn-on fluorescence probe for the detection of Hg²⁺ in living cells

XiaoYuan, TaoHua Leng*, ZhiQian Guo, ChengYun Wang*, JiZhen Li, WeiWei Yang, and Wei-Hong Zhu*

Dyes Pigm., 2019, 161, 403-410.

72      Self-Assembly of a Monochromophore-Based Polymer Enables Unprecedented Ratiometric Tracing of Hypoxia

Shuwen Wang, Kaizhi Gu, Zhiqian Guo*, Chenxu Yan, Tingyuan Yang, Zhuo Chen, He Tian, and Wei-Hong Zhu*

Adv. Mater., 2019, 31 (3).

 

71      An enzyme-activatable probe liberating AIEgens: on-site sensing and long-term tracking of -galactosidase in ovarian cancer cells

Kaizhi Gu, Wanshan Qiu, Zhiqian Guo*, Chenxu Yan, Shiqin Zhu, Defan Yao, Ping Shi, He Tian, and Wei-Hong Zhu

Chem. Sci., 2019, 10 (2), 398-405.

 

70      AND-Logic Based Fluorescent Probe for Selective Detection of Lysosomal Bisulfite in Living Cells

JiZhen Li, YiHang Sun, ChengYun Wang*, ZhiQian Guo*, YongJia Shen, and Wei-Hong Zhu*

Anal. Chem., 2019, 91 (18), 11946-11951.

 

69      Molecularly near-infrared fluorescent theranostics for in vivo tracking tumor-specific chemotherapy

Chenxu Yan, Limin Shi, Zhiqian Guo*, and Wei-hong Zhu

Chin. Chem. Lett., 2019, 30 (10), 1849-1855.

 

68      In vivo ratiometric tracking of endogenous beta-galactosidase activity using an activatable near-infrared fluorescent probe

Limin Shi, Chenxu Yan, Yiyu Ma, Ting Wang, Zhiqian Guo* , and Wei-Hong Zhu

Chem. Commun., 2019, 55 (82), 12308-12311.

67      A fast-response and highly specific Si-Rhodamine probe for endogenous peroxynitrite detection in living cells

Junma Tang, Qiang Li, Zhiqian Guo* , and Wei-hong Zhu

Org. Biomol. Chem., 2019, 17 (7), 1875-1880.

 

2018

66      Near-Infrared Fluorescent Theranostic Cisplatin Prodrug with Transcatheter Intra-Arterial Therapy: Application to Rabbit                                Hepatocellular Carcinoma

Qiang Li, Qi Wang, Saibo Wang, Shiqin Zhu, Tianwen Yuan, Zhiqian Guo, Jun Cao*, He Tian, and Wei-Hong Zhu*

Advanced Therapeutics, 2018, 1 (8).

 

65      Dual-channel near-infrared fluorescent probe for real-time tracking of endogenous c- glutamyl transpeptidase activity

Bing Bai, Chenxu Yan, Yutao Zhang, Zhiqian Guo*, and Wei-Hong Zhu

Chem. Commun., 2018, 54 (87), 12393-12396.

64      Photocaged prodrug under NIR light-triggering with dual-channel fluorescence: in vivo real-time tracking for precise drug delivery

Zhiqian Guo, Yaguang Ma, Yajing Liu, Chenxu Yan, Ping Shi, He Tian, and Wei-Hong Zhu*

Sci China Chem, 2018, 61 (10), 1293-1300.

63      A sequence-activated AND logic dual-channel fluorescent probe for tracking programmable drug release

Chenxu Yan, Zhiqian Guo*, Yajing Liu, Ping Shi, He Tian, and Wei-Hong Zhu*

Chem. Sci., 2018, 9 (29), 6176-6182.

62      Morphology Tuning of Aggregation-Induced Emission Probes by Flash Nanoprecipitation: Shape and Size Effects on in Vivo Imaging

Mingwei Wang, Yisheng Xu*, Yajing Liu, Kaizhi Gu, Jinchao Tan, Ping Shi, Dahai Yang, Zhiqian Guo*, Wei-Hong Zhu, Xuhong Guo*, and Martien A Cohen Stuart

ACS Appl. Mater. Interfaces, 2018, 10 (30), 25186-25193.

61      Molecularly precise self-assembly of theranostic nanoprobes within a single-molecular framework for in vivo tracking of tumor-                    specific chemotherapy

Chenxu Yan, Zhiqian Guo*, Yanyan Shen, Yi Chen, He Tian, and Wei-Hong Zhu*

Chem. Sci., 2018, 9 (22), 4959-4969.

2017 

60        Near-Infrared mitochondria-targeted fluorescent probe for cysteine based on difluoroboron curcuminoid derivatives

     Peng Zhang, Zhiqian Guo*, Chenxu Yan, and Wei-Hong Zhu

     Chin. Chem. Lett., 2017, 28 (10), 1952-1956.

59       GSH-Activated NIR Fluorescent Prodrug for Podophyllotoxin Delivery

           Yajing Liu, Shaojia Zhu, Kaizhi Gu, Zhiqian Guo, Xiaoyu Huang*, Mingwei Wang, Hesham M Amin, Wei-Hong Zhu*, and Ping Shi*

    ACS Appl. Mater. Interfaces, 2017, 9 (35), 29496-29504.

58       Peptide Receptor-Targeted Fluorescent Probe: Visualization and Discrimination between Chronic and Acute Ulcerative Colitis

           Meiying Zeng, Andong Shao, Hui Li, Yan Tang, Qiang Li, Zhiqian Guo, Chungen Wu, Yingsheng Cheng*, He Tian, and Wei-Hong                   Zhu*

    ACS Appl. Mater. Interfaces, 2017, 9 (15), 13029-13036.

57       A FRET Fluorescent Probe for α-Ketoglutaric Acid Based on Rhodamine and BODIPY

     Zhiqian Guo, Ye He, Pengwei Jin, Junma Tang, Shiqin Zhu, and Wei-Hong Zhu*

     IMAGING SCIENCE AND PHOTOCHEMISTRY, 2017, 35 (3), 265-273.

56        Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide

     Junma Tang, Zhiqian Guo*, Yutao Zhang, Bing Bai, and Wei-Hong Zhu

     Chem Commun (Camb), 2017, 53 (76), 10520-10523.

2016

55      In Situ Ratiometric Quantitative Tracing of Intracellular Leucine Aminopeptidase Activity via an Activatable Near-Infrared Fluorescent            Probe

          Kaizhi Gu, Yajing Liu, Zhiqian Guo*, Cheng Lian, Chenxu Yan, Ping Shi, He Tian, and Wei-Hong Zhu

          ACS Appl. Mater. Interfaces, 2016, 8 (40), 26622-26629.

54      Selective “turn-on” probes for CN− based on a fluorophore skeleton of 1,3-dihydroisobenzofuran

          Xuesong Shang, Niantai Li, Zhiqian Guo, and Peinian Liu*

          Dyes Pigm., 2016, 132, 167-176.

53      Dual-channel NIR activatable theranostic prodrug for in vivo spatiotemporal tracking thiol-triggered chemotherapy

Mingzhou Ye, Xiaohang Wang, Jianbin Tang*, Zhiqian Guo*, Youqing Shen, He Tian, and Wei-Hong Zhu*

Chem. Sci., 2016, 7 (8), 4958-4965.

52      Rational design of novel near-infrared fluorescent DCM derivatives and their application in bioimaging

          Xiaohang Wang, Zhiqian Guo*, Shiqin Zhu, Yajing Liu, Ping Shi, He Tian, and Wei-Hong Zhu

          J Mater Chem B, 2016, 4 (27), 4683-4689.

 

51      Real-Time Tracking and In Vivo Visualization of β-Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared                        Fluorescent Probe

Kaizhi Gu, Yisheng Xu, Hui Li, Zhiqian Guo*, Shaojia Zhu, Shiqin Zhu, Ping Shi, Tony D James, He Tian, and Wei-Hong Zhu*

J. Am. Chem. Soc., 2016, 138 (16), 5334-5340.

 

50      Photoswitching between black and colourless spectra exhibits resettable spatiotemporal logic

Yue Wu, Zhiqian Guo, Wei-Hong Zhu*, Wei Wan, Junji Zhang, Wenlong Li, Xin Li, He Tian, and Alexander D. Q. Li*

Mater. Horiz., 2016, 3 (2), 124-129.

49      Enabling Light Work in Helical Self-Assembly for Dynamic Amplification of Chirality with Photoreversibility

Yunsong Cai, Zhiqian Guo, Jianmei Chen, Wenlong Li, Liubiao Zhong, Ya Gao, Lin Jiang, Lifeng Chi*, He Tian, and Wei-Hong Zhu*

J. Am. Chem. Soc., 2016, 138 (7), 2219-2224.

48      Near-infrared AIE-active fluorescent organic nanoprobes with remarkable tumor-targeting efficacy: Shape-specific effects via                        tailoring quinoline–malononitrile

          Wei-Hong Zhu*, Zhiqian Guo, Andong Shao, and Xumeng Wu

          Nanomed. Nanotechnol. Biol. Med., 2016, 12 (2), 468-469.

47       In vivo imaging β-galactosidase activity using a near-infrared dual-channel fluorescent probe

           Kaizhi Gu, Zhiqian Guo*, He Tian, and Wei-Hong Zhu

           Nanomed. Nanotechnol. Biol. Med., 2016, 12 (2), 514-514.

 

46      A dual fluorescent prodrug for in vivo tumor imaging and therapy

Minghzou Ye*, Xiaohang Wang, Jianbin Tang*, Zhiqian Guo, He Tian, Wei-hong Zhu, and Youqing Shen

Nanomed. Nanotechnol. Biol. Med., 2016, 12 (2), 472-472.

 

45      Insight into aggregation-induced emission characteristics of red-emissive quinoline-malononitrile by cell tracking and real-time                  trypsin detection

Andong Shao, Zhiqian Guo*, Shaojia Zhu, Shiqin Zhu, Ping Shi, He Tian and Weihong Zhu*

Chem. Sci., 2014, 5, 1383-1389.

 

44      Transforming the recognition site of 4-hydroxyaniline into 4-methoxyaniline grafted onto a BODIPY core switches the selective                    detection of peroxynitrite to hypochlorous acid

Chunchang Zhao*, Jiancai An, Li Zhou, Qiang Fei, Feiyi Wang, Jie Tan, Ben Shi, Rui Wang*, Zhiqian Guo, and Wei-Hong Zhu

Chem. Commun. (Camb), 2016, 52 (10), 2075-2078.

 

43       A novel colorimetric and ratiometric NIR fluorescent sensor for glutathione based on dicyanomethylene-4H-pyran in living cells 

           Xumeng Wu, Andong Shao, Shiqin Zhu, Zhiqian Guo, and Wei-Hong Zhu*

           Sci. China Chem., 2015, 59 (1), 62-69.

42       Near-infrared cyanine-based sensor for Fe³⁺ with high sensitivity: its intracellular imaging application in colorectal cancer cells

           Mingming Zhu, Chuanxing Shi, Xitao Xu, Zhiqian Guo*, and Wei-Hong Zhu

           RSC Adv., 2016, 6 (103), 100759-100764.

41       Long wavelength AIEgen of quinoline-malononitrile

           Zhiqian Guo, Andong Shao, and Wei-Hong Zhu*

           J. Mater. Chem. C, 2016, 4 (14), 2640-2646.

2015

40      Förster Resonance Energy Transfer Switchable Self-Assembled Micellar Nanoprobe: Ratiometric Fluorescent Trapping of                                Endogenous H2S Generation via Fluvastatin-Stimulated Upregulation

Chunchang Zhao, Xiuli Zhang, Kaibin Li, Shaojia Zhu, Zhiqian Guo, Lili Zhang, Feiyi Wang, Qiang Fei, Sihang Luo, Ping Shi, He Tian, and Wei-Hong Zhu

J. Am. Chem. Soc., 2015, 137 (26), 8490-8498.

39      Far‐Red and Near‐IR AIE‐Active Fluorescent Organic Nanoprobes with Enhanced Tumor‐Targeting Efficacy: Shape‐Specific Effects

Andong Shao, Yongshu Xie, Shaojia Zhu, Zhiqian Guo*, Shiqin Zhu, Jin Guo, Ping Shi, Tony D James, He Tian, and Wei-Hong Zhu*

Angew. Chem. Int. Ed., 2015, 54 (25), 7275-7280.

38      A dual-response BODIPY-based fluorescent probe for the discrimination of glutathione from cystein and homocystein

Feiyi Wang, Li Zhou, Chunchang Zhao*, Rui Wang, Qiang Fei, Sihang Luo, Zhiqian Guo, He Tian, and Wei-Hong Zhu*

Chem. Sci., 2015, 6 (4), 2584-2589.

37      Optimizing the Chemical Recognition Process of a Fluorescent Chemosensor for α-Ketoglutarate

          Ye He, Zhiqian Guo*, Pengwei Jin, Changhong Jiao, He Tian, and Wei-Hong Zhu

          Ind. Eng. Chem. Res., 2015, 54 (11), 2886–2893.

36      Facile Preparation of AIE-Active Fluorescent Nanoparticles through Flash Nanoprecipitation

Mingwei Wang, Nan Yang, Zhiqian Guo*, Kaizhi Gu, Andong Shao, Weihong Zhu, Yisheng Xu*, Jie Wang, Robert K. Prud’homme, and Xuhong Guo*

Ind. Eng. Chem., Res., 2015, 54 (17), 4683–4688.

35        A redox-activated fluorescence switch based on a ferrocene–fluorophore–boronic ester conjugate

            Meng Li, Zhiqian Guo, Wei-Hong Zhu*, Frank Marken*, and Tony D James*

            Chem. Commun. (Camb), 2015, 51 (7), 1293-1296.

2014

 34     A naked-eye and ratiometric near-infrared probe for palladium via modulation of a π-conjugated system of cyanines

Xiaohang Wang, Zhiqian Guo*, Shiqin Zhu, He Tian and Weihong Zhu*

Chem. Commun., 2014, 50 (88), 13525-13528.

 

 

33      Fabrication of mesoporous silica nanoparticles hybridised with fluorescent AIE-active quinoline-malononitrile for drug delivery and              bioimaging

Si Yao, Andong Shao, Wenru Zhao*, Shaojia Zhu, Ping Shi, Zhiqian Guo*, Weihong Zhu and Jianlin Shi*

RSC Adv., 2014, 4 (103), 58976-58981.

32      Development of a Small Molecule Probe Capable of Discriminating Cysteine, Homocysteine, and Glutathione with Three Distinct                  Turn‐On Fluorescent Outputs

Feiyi Wang, Zhiqian Guo, Xia Li, Xiuai Li, Chunchang Zhao*

Chemistry-a European Journal, 2014, 20 (36), 11471-11478.

 31     Synthesis of a highly Zn²⁺-selective cyanine-based probe and its use for tracing endogenous zinc ions in cells and organisms

Zhiqian Guo, Gun-Hee Kim, Juyoung Yoon, and Injae Shin*

Nat. Protoc., 2014, 9 (6), 1245-1254.

 

 30     In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug

Xumeng Wu, Xuanrong Sun, Zhiqian Guo*, Jianbin Tang*, Youqing Shen, Tony D. James, He Tian, and Weihong Zhu*

J. Am. Chem. Soc., 2014, 136 (9), 3579-3588.

 

 29     Recent progress in the development of near-infrared fluorescent probes for bioimaging applications

Zhiqian Guo, Sookil Park, Juyoung Yoon* and Injae Shin*

Chem. Soc. Rev., 2014, 43 (1), 16-29.

28      Selective homocysteine turn-on fluorescent probes and their bioimaging applications

Hye Yeon Lee, Yoon Pyo Choi, Sunkyung Kim, Taejin Yoon, Zhiqian Guo, Songyi Lee, K. M. K. Swamy, Gyoungmi Kim, Jin Yong Lee*, Injae Shin* and Juyoung Yoon*

Chem. Commun., 2014, 50 (53), 6967-6969.

27      Cyanine conjugated silica nanoparticles as NIR fluorescent probes for bioimaging applications

Dabin Kim, Jun Yin, Zhiqian Guo*, Younghee Kwon, Dayoung Lee, Gyoungmi Kim, Ji-Hwan Ryu, and Juyoung Yoon*

Abstracts of Papers of the American Chemical Society, 2014, 248.

26     Rational design of a turn-on fluorescent sensor for α-ketoglutaric acid in a microfluidic chip

         Pengwei Jin, Changhong Jiao, Zhiqian Guo*, Ye He, Shiqin Zhu, He Tian and Weihong Zhu*

         Chem. Sci., 2014, 5 (10), 4012-4016.

2013

25      Near-Infrared Colorimetric and Fluorescent Cu²⁺ Sensors Based on Indoline–Benzothiadiazole Derivatives via Formation of Radical              Cations

Xumeng Wu, Zhiqian Guo*, Yongzhen Wu, Shiqin Zhu, Tony D. James, and Weihong Zhu*

ACS Appl. Mater. Interfaces, 2013, 5 (22), 12215-12220.

24      Highly selective ratiometric fluorescent probe for Au3+ and its application to bioimaging

Ji Young Choi, Gun-Hee Kim, Zhiqian Guo, Hye Yeon Lee, K.M.K. Swamy, Jaeyoung Pai, Seunghoon Shin, Injae Shin*, and JuyoungYoon*

Biosensors & Bioelectronics, 2013, 49, 438-441.

23     Screen-Printed Red Luminescent Copolymer Film Containing Cyclometalated Iridium(III) Complex as a High-Permeability Dissolved-             Oxygen Sensor for Fermentation Bioprocess

         Pengwei Jin, Zhiqian Guo, Ju Chu, Jun Tan, Siliang Zhang, and Weihong Zhu*

         Ind. Eng. Chem Res., 2013, 52 (11), 3980-3987.

22     Self-Assembly Solid-State Enhanced Red Emission of Quinolinemalononitrile: Optical Waveguides and Stimuli Response

         Chuanxing Shi, Zhiqian Guo, Yongli Yan, Shiqin Zhu, Yongshu Xie, Yong Sheng Zhao*, Weihong Zhu*, and He Tian

         ACS Appl. Mater. Interfaces, 2013, 5 (1), 192-198.

21     A Multiaddressable Photochromic Bisthienylethene with Sequence-Dependent Responses: Construction of an INHIBIT Logic Gate                 and a Keypad Lock

         Shangjun Chen, Zhiqian Guo, Shiqin Zhu, Wen-e Shi, and Weihong Zhu*

         ACS Appl. Mater. Interfaces, 2013, 5 (12), 5623-5629.

20     Constructing NIR silica–cyanine hybrid nanocomposite for bioimaging in vivo: a breakthrough in photo-stability and bright                           fluorescence with large Stokes shift

         Xumeng Wu, Shu Chang, Xuanrong Sun, Zhiqian Guo, Yongsheng Li*, Jianbin Tang*, Youqing Shen, Jianlin Shi, He Tian and Weihong           Zhu*

         Chem. Sci., 2013, 4 (3), 1221-1228.

2012

19      A cyanine-based fluorescent sensor for detecting endogenous zinc ions in live cells and organisms

Zhiqian Guo, Gun-Hee Kim, Injae Shin*, and JuyoungYoon*
Biomaterials, 2012, 33 (31), 7818-7827.

18     A Benzobisimidazolium-Based Fluorescent and Colorimetric Chemosensor for CO2
         Zhiqian Guo, Na Ri Song, Jong Hun Moon, Myounwoo Kim, Eun Jin Jun, Jiyoung Choi, Jin Yong Lee*, Christopher W. Bielawski*,                   Jonathan L. Sessler*, and Juyoung Yoon*
         J. Am. Chem. Soc., 2012, 134 (43), 17846-17849.

17      Sensing Performance Enhancement via Acetate-Mediated N-Acylation of Thiourea Derivatives: A Novel Fluorescent Turn-On                        Hg2+ Chemodosimeter

Xinyu Lu, Zhiqian Guo, Mingxiang Feng, and Weihong Zhu*
ACS Appl. Mater. Interfaces, 2012, 4 (7), 3657-3662.

16     Dicyanomethylene-4H-pyran chromophores for OLED emitters, logic gates and optical chemosensors
         Zhiqian Guo, Weihong Zhu* and He Tian
         Chem. Commun., 2012, 48 (49), 6073-6084.

15     A novel NIR fluorescent turn-on sensor for the detection of pyrophosphate anion in complete water system

         Weihong Zhu*, Xiaomei Huang, Zhiqian Guo, Xumeng Wu, Huihui Yua and He Tian

         Chem. Commun., 2012, 48 (12), 1784-1786.

14      A new rhodamine derivative bearing benzothiazole and thiocarbonyl moieties as a highly selective fluorescent and colorimetric                    chemodosimeter for Hg2+

Fang Wang, Seong-Won Nam, Zhiqian Guo, Sungsu Park, and JuyoungYoon*

Sensors and Actuators B: Chemical, 2012, 161 (1), 948-953.

13     Recognition and sensing of various species using boronic acid derivatives
         Zhiqian Guo, Injae Shin* and Juyoung Yoon*
         Chem. Commun., 2012, 48 (48), 5956-5967.

12      A highly selective ratiometric near-infrared fluorescent cyanine sensor for cysteine with remarkable shift and its application in                      bioimaging

Zhiqian Guo, SeongWon Nam, Sungsu Park* and Juyoung Yoon*

Chem. Sci., 2012, 3 (9), 2760-2765.

11     Recent Application Progress on Aggregation-Induced Emission

         Guosheng Zhao, Chuanxing Shi, Zhiqian Guo, Weihong Zhu and Shiqin Zhu*

         Chin. J. Org. Chem., 2012, 32 (9), 1620-1632.

2011

10     Helical Assembly Induced by Hydrogen Bonding from Chiral Carboxylic Acids Based on Perylene Bisimides
       Xinyu Lu, Zhiqian Guo, Chunyu Sun, He Tian, and Weihong Zhu*
       J. Phys. Chem. B, 2011, 115 (37), 10871-10876.

 

9     Recent progress on polymer-based fluorescent and colorimetric chemosensors

         Ha Na Kim, Zhiqian Guo, Weihong Zhu, Juyoung Yoon* and He Tian*

         Chem. Soc. Rev., 2011, 40 (1), 79-93.

2010

8     Near‐Infrared Cell‐Permeable Hg²⁺‐Selective Ratiometric Fluorescent Chemodosimeters and Fast Indicator Paper for MeHg+ Based on        Tricarbocyanines

      Zhiqian Guo, Weihong Zhu*, Mingming Zhu, Xumeng Wu, and He Tian*

      Chemistry-a European Journal, 2010, 16 (48), 14424-14432.

 

7     Hydrophilic Copolymer Bearing Dicyanomethylene-4H-pyran Moiety As Fluorescent Film Sensor for Cu2+ and Pyrophosphate Anion            Zhiqian Guo, Weihong Zhu*, and He Tian*

      Macromolecules, 2010, 43 (2), 739-744.

2009

6      A hydrophilic fluorescent polymer containing naphthalimide moiety as chemosensor for microbioreactors

      LiangJun Shen, WeiHong Zhu*, XianLe Meng, ZhiQian Guo, and He Tian

      Science in China Series B: Chemistry, 2009, 52 (6), 821-826.

5     Multiple Logic Fluorescent Thermometer System Based on N-Isopropylmethacrylamide Copolymer Bearing Dicyanomethylene-4H-             pyran Moiety

      Zhiqian Guo, Weihong Zhu*, Yuyan Xiong, and He Tian*

      Macromolecules, 2009, 42 (5), 1448-1453.

2008

4     A colorimetric and fluorescent turn-on sensor for pyrophosphate anion based on a dicyanomethylene-4H-chromene framework

Xiaomei Huang, Zhiqian Guo, Weihong Zhu*, Yongshu Xiea and He Tian*
Chem. Commun., 2008,  (41), 5143-5145.

 3     Intramolecular Charge-Transfer Process Based on Dicyanomethylene-4H-pyran Derivative:  An Integrated Operation of Half-                         Subtractor and Comparator

Zhiqian Guo, Ping Zhao, Weihong Zhu*, Xiaomei Huang, Yongshu Xie, and He Tian*
J. Phys. Chem. C, 2008, 112 (17), 7047-7053.

 

2007

2     A Fluorophore Capable of Crossword Puzzles and Logic Memory

       Zhiqian Guo, Weihong Zhu*, Liangjun Shen, He Tian*

       Angew. Chem. Int. Ed., 2007, 46 (29), 5549-5553.

2006

1     Highly stable and fluorescent switching spirooxazines

      Xianle Meng, Weihong Zhu*, Zhiqian Guo, Junqing Wang, and HeTian*

      Tetrahedron, 2006, 62 (42), 9840-9845.