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成果及论文

代表性文章(独立PI期间)

1.Yang Yang¥; Zhenyong Wu¥; Laurie Wang; Kaifeng Zhou; Kai Xia; Qiancheng Xiong; Longfei Liu; Zhao Zhang; Edwin R Chapman; Yong Xiong; Thomas J Melia; Erdem Karatekin; Hongzhou Gu*; Chenxiang Lin*. “Sorting liposomes of distinct sizes by DNA-brick assisted centrifugation.” Nature Chemistry 2021, 13, 335-342.

2.Youli Jia¥; Liman Chen¥; Jin Liu; Wei Li; Hongzhou Gu*. “DNA Catalyzed Efficient Production of Single-stranded DNA Nanostructures.” Chem 2021, 7, 4, 959-981.

3.Qingting Li; Zongxuan Tong; Yichun Cao; Hongzhou Gu*. “DNAs catalyzing DNA nanoconstruction.” Chem 2021, DOI: 10.1016/j.chempr.2021.08.008.

4.Canyu Zhang; Qingting Li; Tianbin Xu; Wei Li; Yungang He; Hongzhou Gu*. “New DNA-hydrolyzing DNAs isolated from an ssDNA library carrying a terminal hybridization stem.” Nucleic Acids Research 2021, 49, 11, 6364-6374.

5.Xinyu Du¥; Xiaoqin Cheng¥; Wei Li; Zhilei Ge; Chunjiu Zhong; Chunhai Fan; Hongzhou Gu*. “Engineering allosteric ribozymes to detect thiamine pyrophosphate in whole blood.” Analytical Chemistry 2021, 93, 9, 4277-4284.

6.Qingting Li; Shu Zhang; Wei Li; Zhilei Ge; Chunhai Fan; Hongzhou Gu*. “Programming CircLigase catalysis for DNA rings and topologies.” Analytical Chemistry 2021, 93, 1801-1810.

7.Jin Liu; Hongzhou Gu*. “Biotechnological production of ssDNA with DNA-hydrolyzing deoxyribozymes.” STAR Protocols 2021, 2, 2, 100531.

8.Huiyan Li; Fangfei Yin; Xinyi Li; Wannan Jia; Jia Ding; Li Zhang; Zhonghua Wang; Qinqin Hu; Jieliang Zuo; Huliang Jia; Lihua Wang; Chunhai Fan*; Hongzhou Gu*; Jian Wu*. “Novel aptasensor-based assay of sonic hedgehog ligand for detection of portal vein invasion of hepatocellular carcinoma.” Biosensors and Bioelectronics 2021, 174, 112738.

9.Dong-Jie Tang¥; Xinyu Du¥; Qiang Shi¥; Jian-Ling Zhang¥; Yuan-Ping He; Yan-Miao Chen; Zhenhua Ming; Dan Wang; Wan-Ying Zhong; Yu-Wei Liang; Jin-Yang Liu; Jian-Ming Huang; Yun-Shi Zhong; Hongzhou Gu*; Ji-Liang Tang*. “A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA.” Nature Communications 2020, 11, 2794, 1-11.

10.Kai Xia; Jianlei Shen; Qian Li; Chunhai Fan*; Hongzhou Gu*. “Near-Atomic Fabrication with Nucleic Acids.” ACS Nano 2020, 14, 1319-1337.

11.Ziyi Wang; Xiao Chu; Na Li; Lingling Fu; Hongzhou Gu*; Nan Zhang*. “Engineered DNA nanodrugs alleviate inflammation in inflammatory arthritis.” International Journal of Pharmaceutics 2020, 577, 119047.

12.Zongxuan Tong; Qinqin Hu; Hongzhou Gu*. “Deoxyribozymes: selection, biosensing and outlook.” Chemical Journal of Chinese Universities 2020, 41, 2345-2355.

13.Qinqin Hu¥; Hua Li¥; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. “DNA Nanotechnology Enabled Drug Delivery systems.” Chemical Reviews 2019, 119, 6459-6506.

14.Hua Li; Jin Liu; Hongzhou Gu*. “Targeting Nucleolin to Obstruct Vasculature Feeding with An Intelligent DNA Nanorobot.” Journal of Cellular and Molecular Medicine 2019, 23, 2248-2250.

15.Xinyu Du¥; Xin Zhong¥; Wei Li; Hua Li*; Hongzhou Gu*. “Retraining and Optimizing DNA-Hydrolyzing Deoxyribozymes for Robust Single- and Multiple-Turnover Activities.” ACS Catalysis 2018, 8, 5996-6005.

16.Zhilei Ge¥; Hongzhou Gu¥; Qian Li; Chunhai Fan*. “Concept and Development of Framework Nucleic Acids.” Journal of the American Chemical Society 2018, 140, 51, 17808-17819.

17.Qinqin Hu; Sheng Wang; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. “DNA Nanostructure-Based Systems for Intelligent Delivery of Therapeutic Oligonucleotides.” Advanced Healthcare Materials 2018, 7, 1701153.

18.Hongzhou Gu*. “Single-molecule Genotyping with Nanoscale DNA Shape IDs.” Science China Chemistry 2017, 60, 1111-1112.

代表性文章(博士-博后期间)

1Hongzhou Gu; Kazuhiro Furukawa; Zasha Weinberg; Daniel F. Berenson; Ronald R. Breaker. Small, Highly-active DNAs that Hydrolyze DNA. Journal of the American Chemical Society 2013, 135, 9121-9129.

2Hongzhou Gu; Ronald R. Breaker. Production of Single-stranded DNAs by Self-cleavage of Rolling-circle Amplification Products. BioTechniques 2013, 54, 337-343.

3Hongzhou Gu; Kazuhiro Furukawa; Ronald R. Breaker. Engineered Allosteric Ribozymes that Sense the Bacterial Second Messenger c-di-GMP. Analytical Chemistry 2012, 84, 4935-4941.

4Hongzhou Gu; Jie Chao; Shou-Jun Xiao; Nadrian C. Seeman. A Proximity-Based Programmable DNA Nanoscale Assembly Line. Nature 2010, 465, 202-205.

5Hongzhou Gu; Wei Yang; Nadrian C. Seeman. “DNA Scissors Device Used to Measure MutS Binding to DNA Mis-Pairs.” Journal of the American Chemical Society 2010, 132, 4352-4357.

6Hongzhou Gu; Jie Chao; Shou-Jun Xiao; Nadrian C. Seeman. Dynamic Patterning Programmed by DNA Tiles Captured on a DNA Origami Substrate. Nature Nanotechnology 2009, 4, 245-248.