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成果及论文

研究论文

22. 贺宏伟, 徐丹, 徐功*. α-羟基-γ-丁内酯类衍生物的设计、合成及抗植物病毒活性. 农药学学报. 2023, 25 (6), 1261-1269.

21. Yantao Li, Han Yang, Yidan Ma, Yuan Cao, Dan Xu*, Xili Liu, and Gong Xu*, Discovery of Novel Pyrazol-5-yl-benzamide Derivatives Containing a Thiocyanato Group as Broad-Spectrum Fungicidal Candidates, J. Agric. Food Chem. 2023, 71 (46), 17700–17712.

20. Hong-Wei He, Dan Xu, Ke-Huan Wu, Zheng-Yi Lu, Xili Liu, Gong Xu*, Discovery of Novel Salicylaldehyde Derivatives Incorporating an α-Methylene-γ-Butyrolactone Moiety as Fungicidal Agents, Pest. Manag. Sci. 2023, 79 (12), 5015-5028.

19. Yuan Chi, Hong-Wei He, Cai-Yun Chen, Si-Ying Zhao, Huan Zhou, Dan Xu, Xili Liu, Gong Xu*, Furofuran Lignans for Plant Protection: Discovery of Sesamolin and Its Derivatives as Novel Anti-Tobacco Mosaic Virus and Antibacterial Agents, J. Agric. Food Chem. 2023, 71 (28), 10798-10808.

18. Wen-Bo Han+,*, Yi-Jie Zhai+, Rong Zhang, Xu-Shun Gong, Jia-Qian Li, Gong Xu*, Xinxiang Lei, Liangcheng Du, Jin-Ming Gao*, Tricrilactones A–H, Potent Antiosteoporosis Macrolides with Distinctive Ring Skeletons from Trichocladium crispatum, an Alpine Moss-Associated Fungus, Angew. Chem. Int. Ed. 2023, 62, e2023007.

17. Rongrong Xie, Huan Zhou, Hui Lu, Yawei Mu, Gong Xu*, Mingxin Chang*, Transition-Metal-Catalyzed Asymmetric Reductive Amination and Amidation Cascade Reaction for the Synthesis of Piperazinones, Org. Lett. 2022, 24 (49), 9033–9037.

16. Hong-Wei He, Yuan Chi, Cai-Yun Chen, Fei-Yu Wang, Jia-Xin Wang, Dan Xu, Huan Zhou*, Gong Xu*, Synthesis and Structure–Activity Relationship Studies of Nicotlactone Analogues as Anti-TMV Agents, Synthesis 2022, 54 (16), 3642-3650.

15. Hong-Wei He, Fei-Yu Wang, Danyang Zhang, Cai-Yun Chen, Dan Xu, Huan Zhou*, Xili Liu, Gong Xu*, Discovery of Novel α-Methylene-γ-Butyrolactone Derivatives Containing Vanillin Moieties as Antiviral and Antifungal Agents, J. Agric. Food Chem. 2022, 70 (33), 10316–10325.

14. Wei Wang, Jianhua Wang, Jipeng Wu, Mengyun Jin, Junling Li, Shiyang Jin, Wangxiang Li, Dan Xu*, Xili Liu, Gong Xu*, Rational Design, Synthesis, and Biological Evaluation of Fluorine- and Chlorine-Substituted Pyrazol-5-yl-benzamide Derivatives as Potential Succinate Dehydrogenase Inhibitors, J. Agric. Food Chem. 2022, 70 (24), 7566–7575.

13. Wei Wang, Xiang-Jia Liu, Guo-Tai Lin, Ji-Peng Wu, Gong Xu*, Dan Xu*, Novel N-(1H-Pyrazol-5-yl)nicotinamide Derivatives: Design, Synthesis and Antifungal Activity, Chemistry & Biodiversity, 2022, 19, e202101032.

12. Wei Wang; Furan Wu, Yidan Ma, Dan Xu*, Gong Xu*, Study on Synthesis and Antifungal Activity of Novel Benzamides Containing Substituted Pyrazole Unit. Chinese J. Org. Chem. 2022, 42 (2), 607-618.

11. Yuan Chi, Huan Zhou, Hong-Wei He, Yi-Dan Ma, Bo Li, Dan Xu, Jin-Ming Gao*, Gong Xu*, Total Synthesis and Anti-Tobacco Mosaic Virus Activity of the Furofuran Lignan (±)-Phrymarolin II and Its Analogues, J. Nat. Prod. 2021, 84 (11), 2937-2944.

10. Wei Wang, Jianhua Wang, Furan Wu, Huan Zhou, Dan Xu*, Gong Xu*, Synthesis and Biological Activity of Novel Pyrazol-5-yl-benzamide Derivatives as Potential Succinate Dehydrogenase Inhibitors, J. Agric. Food Chem. 2021, 69 (20), 5746-5754.

9. Danyang Zhang#, Dan Xu#, Xinyue Chen, Huan Zhou, Gong Xu*, Divergent Entry to Walsucochin Nortriterpenoids: Total Syntheses of (±)-Walsucochin A and (±)-Walsucochinoids C-F, J. Org. Chem. 2021, 86 (10), 7271-7279.

8. Wei Wang#, Shan Zhang#, Jianhua Wang, Furan Wu, Tao Wang*, Gong Xu*, Bioactivity-Guided Synthesis Accelerates the Discovery of 3‑(Iso)quinolinyl-4-chromenones as Potent Fungicide Candidates, J. Agric. Food Chem. 2021, 69 (1), 491−500.

7. Xinyue Chen#, Danyang Zhang#, Dan Xu, Huan Zhou, Gong Xu*, Remote C–H Activation Strategy Enables Total Syntheses of Nortriterpenoids (±)-Walsucochin B and (±)-Walsucochinoids M and N, Org. Lett. 2020, 22 (17), 6993–6997. (Highlighted by Erick M. Carreira, Viktoria C. Gerken, Synfacts, 2020, 16 (11), 1261.)

6. Xingyu Shen#, Chi P. Ting#, Gong Xu, Thomas J. Maimone*, Programmable Meroterpene Synthesis, Nat. Commun. 2020, 11 (1), 508.

5. Gong Xu, Masha Elkin, Dean J. Tantillo, Timothy R. Newhouse*, Thomas J. Maimone*, Traversing Biosynthetic Carbocation Landscapes in the Total Synthesis of Andrastin and Terretonin Meroterpenes, Angew. Chem. Int. Ed. 2017, 56 (41), 12498–12502.

4. Chi P. Ting#, Gong Xu#, Xianhuang Zeng, Thomas J. Maimone*, Annulative Methods Enable a Total Synthesis of the Complex Meroterpene Berkeleyone A, J. Am. Chem. Soc. 2016, 138 (45), 14868–14871. (#contributed equally) (Highlighted by Erick M. Carreira, Johannes Boshkow, Synfacts, 2017, 13(2), 125.)

3. Gong Xu, Monique Lüthy, Jacqueline Habegger, Philippe Renaud,* Homologation Strategy for the Generation of 1-Chloroalkyl Radicals from Organoboranes, J. Org. Chem. 2016, 81 (4), 1506–1519.

2. Gong Xu, Philippe Renaud*, Intramolecular Cyclopropanation of 1,4-Dienes through Hydroboration–Homologation: Easy Access to Bicyclo[3.1.0]hexanes, Angew. Chem. Int. Ed. 2016, 55 (11), 3657–3661.

1. Li-Hua Huang, Yan-Guang Wang, Gong Xu, Xiang-Hua Zhang, Yong-Fei Zheng, Hui-Li He, Wen-Zheng Fu, Hong-Min Liu*, Novel 4-Azasteroidal N-Glycoside Analogues Bearing Sugar-like D ring: Synthesis and Anticancer Activities. Bioorg. Med. Chem. Lett. 2011, 21 (20), 6203-6205.


授权发明专利

5. 徐功, 池源, 徐丹, 贺宏伟; 含芳基的饱和γ-丁内酯类化合物及其制备方法和在抗植物病毒方面的应用, 2024-09-10, 中国, ZL202310701246.0;

4. 徐丹, 王伟, 黄家川, 陆正仪, 赵思颖, 徐功; 含氟吡唑苯乙酰胺类衍生物及其应用, 2023-12-08, 中国, ZL202310109208.6;

3. 徐功, 贺宏伟, 徐丹, 陈彩云; α-亚甲基-γ-丁内酯结构的酚类衍生物、制备方法及其应用, 2023-02-28, 中国, ZL202111461726.1;

2. 徐功, 王伟, 徐丹; 含氟吡唑酰胺类衍生物、制备方法及其应用, 2023-02-24, 中国, ZL202010071859.7;

1. 徐功, 徐丹, 池源, 贺宏伟; 一种含3,7-二氧杂双环[3,3,0]辛烷结构的木脂素类化合物及其制备方法和应用, 2022-10-18, 中国, ZL202110920864.5.