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徐功 教授、博士生导师    

徐功,男,1984年生于河南新野西北农林科技大学教授,博士生导师。2007年本科毕业于郑州大学化学系化学专业,获理学学士学位,同年被保送到本校攻读硕士学位,专业是药物化学,师从刘宏民教授。2010年获得理学硕士学位后,20111月至20156月,在瑞士伯尔尼大学Philippe Renaud教授研究小组从事硼化学及自由基化学的研究,获得化学与分子科学专业博士学位。201511月至201710月,在美国加州大学伯克利分校Thomas J. Maimone教授研究小组从事复杂活性天然萜类化合物的全合成研究。20183月至今,在西北农林科技大学植物保护学院农药学系从事教学和科研工作。现兼任陕西省植物保护学会理事,《农药学学报》首届青年编辑委员会常务编委。主要从事天然产物全合成及绿色农药创制方面的研究,先后主持国家自然科学基金青年项目、陕西省重点研发计划项目、国家自然科学基金面上项目、十四五国家重点研发计划课题等科研项目,在天然产物全合成和新农药分子发现研究方面取得了重要突破,研究成果在《J. Am. Chem. Soc.》、《Angew. Chem. Int. Ed.》、《Org. Lett.》、《J. Agric. Food Chem.》、《Pest Manag. Sci.》、《J. Nat. Prod.》和《J. Org. Chem.》等国际著名期刊发表研究论文20余篇,获授权发明专利4项。


代表性论文

1. Gong Xu, Philippe Renaud*, Intramolecular Cyclopropanation of 1,4-Dienes through Hydroboration–Homologation: Easy Access to Bicyclo[3.1.0]hexanes, Angew. Chem. Int. Ed. 2016, 55 (11), 3657–3661.

2. Chi P. Ting#, Gong Xu#, Xianhuang Zeng, Thomas J. Maimone*, Annulative Methods Enable a Total Synthesis of the Complex Meroterpene Berkeleyone A, J. Am. Chem. Soc. 2016, 138 (45), 14868–14871. (#contributed equally) (Highlighted by Erick M. Carreira, Johannes Boshkow, Synfacts, 2017, 13(2), 125.)

3. Gong Xu, Masha Elkin, Dean J. Tantillo, Timothy R. Newhouse*, Thomas J. Maimone*, Traversing Biosynthetic Carbocation Landscapes in the Total Synthesis of Andrastin and Terretonin Meroterpenes, Angew. Chem. Int. Ed. 2017, 56 (41), 12498–12502.

4. Xinyue Chen#, Danyang Zhang#, Dan Xu, Huan Zhou, Gong Xu*, Remote C–H Activation Strategy Enables Total Syntheses of Nortriterpenoids (±)-Walsucochin B and (±)-Walsucochinoids M and N, Org. Lett. 2020, 22 (17), 6993–6997. (Highlighted by Erick M. Carreira, Viktoria C. Gerken, Synfacts, 2020, 16 (11), 1261.)

5. Wei Wang#, Shan Zhang#, Jianhua Wang, Furan Wu, Tao Wang*, Gong Xu*, Bioactivity-Guided Synthesis Accelerates the Discovery of 3‑(Iso)quinolinyl-4-chromenones as Potent Fungicide Candidates, J. Agric. Food Chem. 2021, 69 (1), 491−500.

6. Wei Wang, Jianhua Wang, Furan Wu, Huan Zhou, Dan Xu*, Gong Xu*, Synthesis and Biological Activity of Novel Pyrazol-5-yl-benzamide Derivatives as Potential Succinate Dehydrogenase Inhibitors, J. Agric. Food Chem. 2021, 69 (20), 5746-5754.

7. Wei Wang, Jianhua Wang, Jipeng Wu, Mengyun Jin, Junling Li, Shiyang Jin, Wangxiang Li, Dan Xu*, Xili Liu, Gong Xu*, Rational Design, Synthesis, and Biological Evaluation of Fluorine- and Chlorine-Substituted Pyrazol-5-yl-benzamide Derivatives as Potential Succinate Dehydrogenase Inhibitors, J. Agric. Food Chem. 2022, 70 (24), 7566–7575.

8. Hong-Wei He, Fei-Yu Wang, Danyang Zhang, Cai-Yun Chen, Dan Xu, Huan Zhou*, Xili Liu, Gong Xu*, Discovery of Novel α-Methylene-γ-Butyrolactone Derivatives Containing Vanillin Moieties as Antiviral and Antifungal Agents, J. Agric. Food Chem. 2022, 70 (33), 10316–10325.

9. Wen-Bo Han+,*, Yi-Jie Zhai+, Rong Zhang, Xu-Shun Gong, Jia-Qian Li, Gong Xu*, Xinxiang Lei, Liangcheng Du, Jin-Ming Gao*, Tricrilactones A–H, Potent Antiosteoporosis Macrolides with Distinctive Ring Skeletons from Trichocladium crispatum, an Alpine Moss-Associated Fungus, Angew. Chem. Int. Ed. 2023, 62, e2023007.

10. Yuan Chi, Hong-Wei He, Cai-Yun Chen, Si-Ying Zhao, Huan Zhou, Dan Xu, Xili Liu, Gong Xu*, Furofuran Lignans for Plant Protection: Discovery of Sesamolin and Its Derivatives as Novel Anti-Tobacco Mosaic Virus and Antibacterial Agents, J. Agric. Food Chem. 2023, 71 (28), 10798-10808.

11. Hong-Wei He, Dan Xu, Ke-Huan Wu, Zheng-Yi Lu, Xili Liu, Gong Xu*, Discovery of Novel Salicylaldehyde Derivatives Incorporating an α-Methylene-γ-Butyrolactone Moiety as Fungicidal Agents, Pest. Manag. Sci. 2023, 79 (12), 5015-5028.

12. Yantao Li, Han Yang, Yidan Ma, Yuan Cao, Dan Xu*, Xili Liu, and Gong Xu*, Discovery of Novel Pyrazol-5-yl-benzamide Derivatives Containing a Thiocyanato Group as Broad-Spectrum Fungicidal Candidates, J. Agric. Food Chem. 2023, 71 (46), 17700–17712