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成果及论文

112. Tao He#(co-first author), Yiling Shi#(co-first author), Xiaorong Kou, Meiling Shen, Xiuqi Liang, Xinchao Li, Rui Wu, Qinjie Wu, Changyang Gong*(Corresponding author). Antigenicity and adjuvanticity co-reinforced personalized cell vaccines based on self-adjuvanted hydrogel for post-surgical cancer vaccination. Biomaterials, 2023, 301, 122218. DOI: 10.1016/j.biomaterials.2023.122218

111. Cailing Gan#(co-first author), Yan Wang#(co-first author), Zhongzheng Xiang, Hongyao Liu, Zui Tan, Yuting Xie, Yuqin Yao, Liang Ouyang, Changyang Gong*(Corresponding author), Tinghong Ye*. Niclosamide-loaded nanoparticles (Ncl-NPs) reverse pulmonary fibrosis in vivo and in vitro. Journal of Advanced Research, 2023, 51: 109-120. DOI: 10.1016/j.jare.2022.10.018

110. Wen Yang#(co-first author), Ning Wang#(co-first author), Jin Yang, Chao Liu, Shuang Ma, Xiye Wang, Wenzhen Li, Meiling Shen, Qinjie Wu*, Changyang Gong*(Corresponding author). A Multifunctional ‘Golden Cicada’ Nanoplatform Break the Thermoresistance Barrier to Launch Cascade Augmented Synergistic Effects of Photothermal/Gene Therapy. Journal of Nanobiotechnology, 2023, 21: 228. DOI: 10.1186/s12951-023-01983-3

109. Jin Yang, Liping Bai, Meiling Shen, Xinyu Gou, Zhongzheng Xiang, Shuang Ma, Qinjie Wu, and Changyang Gong*(Corresponding author). A Multiple Stimuli-Responsive NanoCRISPR Overcomes Tumor Redox Heterogeneity to Augment Photodynamic Therapy. ACS Nano, 2023, 17(12): 11414-11426. DOI: 10.1021/acsnano.3c00940

108. Linjiang Song#(co-first author), Jin Yang#(co-first author), Zeyi Qin#(co-first author), Chunqing Ou, Rui Luo, Wen Yang, Li Wang, Ning Wang, Shuang Ma, Qinjie Wu*, Changyang Gong*(Corresponding author). Multi-Targeted and On-Demand Non-Coding RNA Regulation Nanoplatform against Metastasis and Recurrence of Triple-Negative Breast Cancer. Small, 2023, 19(23): 2207576. DOI: 10.1002/smll.202207576

107. Xiaowei Liu#(co-first author), Suleixin Yang#(co-first author), Li Wang#(co-first author), Xinyue Wu, Xinxin Wang, Chunqing Ou, Jin Yang, Linjiang Song, Shiyao Zhou, Qinjie Wu*, Changyang Gong*(Corresponding author). Hierarchically tumor-activated nanoCRISPR-Cas13a facilitates efficient microRNA disruption for multi-pathway-mediated tumor suppression. Theranostics, 2023, 13(9): 2774-2786. DOI: 10.7150/thno.81776

106. Li Wang#(co-first author), Chao Liu#(co-first author), Xinxin Wang, Shuang Ma, Furong Liu, Yi Zhang, Yan Wang, Meiling Shen, Xinyue Wu, Qinjie Wu*, Changyang Gong*(Corresponding author). Tumor-Specific Activated Nano-Domino-CRISPR to Amplify Intrinsic Oxidative and Activate Endogenous Apoptosis for Spatiotemporally Specific Therapy. Biomaterials, 2023, 295, 122056. DOI: 10.1016/j.biomaterials.2023.122056

105. Yan Wang#(co-first author), Xianzhou Huang#(co-first author), Shunyao Zhu, Lu Li, Jin Yang, Jie Li, Li Wang, Shuang Ma, Meiling Shen, Qinjie Wu*(Corresponding author), Changyang Gong. A Quad-Functional On-demand Released Nanomissile Achieves Cascade Amplification therapy of Triple-Negative Breast Cancer Through Reversing Multiple Resistance. Chemical Engineering Journal, 2023, 461: 141816. DOI: 10.1016/j.cej.2023.141816

104. Tao He, Mingxing Hu, Shunyao Zhu, Meiling Shen, Xiaorong Kou, Xiuqi Liang, Lu Li, Xinchao Li, Miaomiao Zhang, Qinjie Wu*, Changyang Gong*(Corresponding author). A tactical nanomissile mobilizing antitumor immunity enables neoadjuvant chemo-immunotherapy to minimize postsurgical tumor metastasis and recurrence. Acta Pharmaceutica Sinica B, 2023, 13(2): 804-818.  DOI: 10.1016/j.apsb.2022.09.017

103. Ning Wang#(co-first author), Chao Liu#(co-first author), Yingjie Li, Dongxue Huang, Xinyue Wu, Xiaorong Kou, Xiye Wang, Qinjie Wu*, Changyang Gong*(Corresponding author)cooperative Nano-CRISPR scaffold potentiates immunotherapy via activation of tumour-intrinsic Pyroptosis. Nature Communications, 2023, 14: 779. DOI: 10.1038/s41467-023-36550-9


2022

102. Furong Liu#(co-first author), Tao He#(co-first author), Songlin Gong, Meiling Shen, Shuang Ma, Xianzhou Huang, Lu Li, Li Wang, Qinjie Wu*(Corresponding author), Changyang Gong. A Tumor pH-Responsive Autocatalytic Nanoreactor as a H2O2 and O2 Self-Supplying Depot for Enhanced ROS-based Chemo/Photodynamic Therapy. Acta Biomaterialia, 2022, 154: 510-522. DOI: 10.1016/j.actbio.2022.10.002

101. Songlin Gong#(co-first author), Xiuqi Liang#(co-first author), Miaomiao Zhang, Lu Li, Tao He, Yuan Yuan, Xinchao Li, Furong Liu, Xi Yang, Meilin Shen, Qinjie Wu*, Changyang Gong*(Corresponding author). Tumor Microenvironment-Activated Hydrogel Platform with Programmed Release Property Evokes a Cascade-Amplified Immune Response against Tumor Growth, Metastasis and Recurrence. Small, 2022, 18(50): 2107061. DOI: 10.1002/smll.202107061

100. Lu Li, Xiuqi Liang, Tao He, Xinchao Li, Xianzhou Huang, Ning Wang, Meilin Shen, Yaqian Shu, Rui Wu, Miaomiao Zhang, Qinjie Wu*, Changyang Gong*(Corresponding author). Multifunctional Light-Activatable Nanocomplex Conducting Temperate-Heat Photothermal Therapy to Avert Excessive Inflammation and Trigger Augmented Immunotherapy. Biomaterials, 2022, 290, 121815. DOI: 10.1016/j.biomaterials.2022.121815

99. Xi Yang, Yuanfeng Wei, Lingnan Zheng, Jia You, Huawei Li, Ling Gao, Changyang Gong*(Corresponding author), Cheng Yi*. Polyethyleneimine-based immunoadjuvants for designing cancer vaccines. Journal of Materials Chemistry B, 2022, 10(40): 8166-8180.  DOI: 10.1039/d2tb01358d

98. Zichao Luo#(co-first author), Xiuqi Liang#(co-first author), Tao He, Xian Qin, Xinchao Li, Yueshan Li, Lu Li, Xian Jun Loh, Changyang Gong*(Corresponding author), Xiaogang Liu*. Lanthanide-Nucleotide Coordination Nanoparticles for STING Activation. Journal of the American Chemical Society, 2022, 144(36), 16366–16377. DOI: 10.1021/jacs.2c03266

97. Rui Luo, Chunqing Ou, Xinchao Li, Yanfang Wang, Wei Du, Gaolin Liang*(Corresponding author)Changyang Gong*(Corresponding author). An Acidity-Initiated Self-Assembly/Disassembly Nanoprobe to Switch on Fluorescence for Tumor Targeted Near-Infrared Imaging. Nano Letters, 2022, 22, 151-156. IF= 12.262  DOI: 10.1021/acs.nanolett.1c03534

96. Xinchao Li, Rui Luo, Xiuqi Liang, Qinjie Wu, Changyang Gong*(Corresponding author)Recent advances in enhancing reactive oxygen species based chemodynamic therapy. Chinese Chemical Letters, 2022, 33(5): 2213-2230. IF=8.455  DOI: 10.1016/j.cclet.2021.11.048

95. Dengshen Zhang, Jun Shi, Guiyou Liang, Daxing Liu, Jian Zhang, Sisi Pan, Yuanfu Lu, Qin Wu, Changyang Gong*(Corresponding author), Yingqiang Guo*. miR-16-5p is a Novel Mediator of Venous Smooth Muscle Phenotypic Switching. Journal of Cardiovascular Translational Research, 2022, in press. IF= 3.216  DOI: 10.1007/s12265-022-10208-1

94. Xi Yang#, Lingyun Zhang#Lingnan Zheng, Yan Wang, Ling Gao, Rui Luo, Xinchao Li, Changyang Gong, Han Luo*, Qinjie Wu*(Corresponding author)An in situ spontaneously-forming micelle-hydrogel system with programable release for sequential therapy of anaplastic thyroid cancer. Journal of Materials Chemistry B, 2022, 10: 1236-1249. IF=7.571  DOI: 10.1039/d1tb01904j

93. Xi Yang, Ling Gao, Ning Wang, Yongjiang Li, Linjiang Song, Tao He, Wenli Zhang, Cheng Yi, Gu He, Qinjie Wu*(Corresponding author), Changyang Gong. A self-assembly reproducible nanoplatform enables cancer phenotypic lethality in solid tumors. Materials & Design, 2022, 214: 110408.  IF=9.417  DOI: 10.1016/j.matdes.2022.110408


2021

92. Xi Yang, Jia You, Yuanfeng Wei, Huawei Li, Ling Gao, Qing Guo, Ying Huang, Changyang Gong*(Corresponding author), Cheng Yi*(Corresponding author). Emerging nanomaterials applied for tackling the COVID-19 cytokine storm. Journal of Materials Chemistry B, 2021, 9(39): 8185-8201. IF= 7.57  DOI: 10.1039/d1tb01446c

91. Chao Liu#(co-first author), Ning Wang#(co-first author), Rui Luo, Lu Li, Wen Yang, Xiye Wang, Meiling Shen, Qinjie Wu*(Corresponding author)Changyang Gong*(Corresponding author)A programmable hierarchical-responsive nanoCRISPR elicits robust activation of endogenous target to treat cancer. Theranostics, 2021, 11(20): 9833-9846. IF= 11.6 DOI: 10.7150/thno.62449

90. Jin Yang, Linjiang Song, Meiling Shen, Xinyu Gou, Liping Bai, Li Wang, Wenli Zhang, Qinjie Wu, Changyang Gong*(Corresponding author). Hierarchically Responsive Tumor-Microenvironment-Activated Nano-Artificial Virus (TMAN) for Precise Exogenous and Endogenous Apoptosis Coactivation. Advanced Functional Materials2021, 31(37): 2104423. IF= 19.924  DOI: 10.1002/adfm.202104423

89. Jin Yang, Zhike Li, Meiling Shen, Yan Wang, Li Wang, Jiamiao Li, Wen Yang, Jie Li, Haijun Li, Xinxin Wang, Qinjie Wu, Changyang Gong*(Corresponding author). Programmable Unlocking Nano-matryoshka-CRISPR Precisely Reverses Immunosuppression to Unleash Cascade Amplified Adaptive Immune Response. Advanced Science, 2021, 8: 2100292. IF= 17.521  DOI: 10.1002/advs.202100292

88. Xiuqi Liang, Lu Li, Xinchao Li, Tao He, Songlin Gong, Shunyao Zhu, Miaomiao Zhang, Qinjie Wu*Changyang Gong*(Corresponding author). A spontaneous multifunctional hydrogel vaccine amplifies the innate immune response to launch a powerful antitumor adaptive immune response. Theranostics, 2021, 11(14): 6936-6949. IF= 11.6  DOI: 10.7150/thno.58173

87. Xianzhou Huang#(co-first author), Chunqing Ou#(co-first author), Yaqian Shu, Yan Wang, Songlin Gong, Rui Luo, Shouchun Chen, Qinjie Wu*(Corresponding author)Changyang Gong*(Corresponding author). A self-sustained nanoplatform reverses TRAIL-resistance of pancreatic cancer through coactivating of exogenous and endogenous apoptotic pathway. Biomaterials, 2021, 272: 120795. IF=15.304  DOI: 10.1016/j.biomaterials.2021.120795

86. Zichao Luo#(co-first author), Tao He#(co-first author), Peng Liu, Zhigao Yi, Shunyao Zhu, Xiuqi Liang, Entang Kang, Changyang Gong*(Corresponding author), Xiaogang Liu*(Corresponding author). Self-adjuvanted molecular activator (SeaMac) nanovaccines promote cancer immunotherapy. Advanced Healthcare Materials, 2021, 10(7): 2170025. IF= 11.092  DOI: 10.1002/adhm.202002080

85. Xiangrong Song, Chao Liu, Ning Wang, Hai Huang, Siyan He, Changyang Gong*(Corresponding author), Yuquan Wei*(Corresponding author). Delivery of CRISPR/Cas Systems for Cancer Gene Therapy and Immunotherapy. Advanced Drug Delivery Reviews, 2021, 168: 158-180. IF= 17.873  DOI: 10.1016/j.addr.2020.04.010

84. Tao He, Xiuqi Liang, Lu Li, Songlin Gong, Xinchao Li, Miaomiao Zhang, Shunyao Zhu, Haitao Xiao, Qinjie Wu*(Corresponding author)Changyang Gong*(Corresponding author). A spontaneously formed and self-adjuvanted hydrogel vaccine triggers strong immune responses. Materials & Design, 2021, 197: 109232. IF= 9.417  DOI: 10.1016/j.matdes.2020.109232

83. Furong Liu, Songlin Gong, Meiling Shen, Tao He, Xiuqi Liang, Yaqian Shu, Xinxin Wang, Shuang Ma, Xinchao Li, Miaomiao Zhang, Qinjie Wu*(Corresponding author)Changyang Gong*(Corresponding author). A Glutathione-activatable Nanoplatform for Enhanced Photodynamic Therapy with Simultaneous Hypoxia Relief and Glutathione DepletionChemical Engineering Journal, 2021, 403: 126305. IF= 16.744  DOI: 10.1016/j.cej.2020.126305

82. Xianzhou Huang#(co-first author), Haijun Li#(co-first author), Chunqing Ou, Yaqian Shu, Rui Luo, Xinchao Li, Shouchun Chen, Qinjie Wu, Changyang GongLei Liu*(Corresponding author). A self-sustaining nanoplatform overcomes TRAIL-resistance of pancreatic cancer by a source-broadening and expenditure-reducing apoptosis strategy. Materials & Design, 2021, 211: 110137. IF= 9.417  DOI: 10.1016/j.matdes.2021.110137


2020

81. Ning Wang, Chao Liu, Zhenghao Lu, Wen Yang, Lu Li, Songlin Gong, Tao He, Chunqing Ou, Linjiang Song, Meiling Shen, Qinjie Wu, Changyang Gong*(Corresponding author). Multistage sensitive nanoCRISPR enable efficient intracellular disruption of immune checkpoints for robust innate and adaptive immune coactivation. Advanced Functional Materials, 2020, 30 (45), 2004940. IF= 19.924  DOI: 10.1002/adfm.202004940

80. Xi Yang, Ling Gao, Qing Guo, Yongjiang Li, Yue Ma, Ju Yang, Changyang Gong*(Corresponding author), Cheng Yi*(Corresponding author). Nanomaterials for radiotherapeutics-based multimodal synergistic cancer therapy. Nano Research, 2020, 13(10): 2579-2594. IF= 10.269  DOI: 10.1007/s12274-020-2722-z

79. Fan Jiang#(co-first author), Yunqi Zhu, Changyang Gong*(Corresponding author), Xin Wei*(Corresponding author). Atherosclerosis and Nanomedicine Potential: Current Advance and Future Opportunities. Current Medicinal Chemistry, 2020, 27(21), 3534-3554. IF= 4.74  DOI: 10.2174/0929867326666190301143952

78. Suleixin Yang#(co-first author), Chunqing Ou#(co-first author), Li Wang#(co-first author), Xiaowei Liu, Jin Yang, Xinxin Wang, Meilin Wang, Meiling Shen, Qinjie Wu, Changyang Gong*(Corresponding author). Virus-Esque Nucleus-Targeting Nanoparticles Deliver Trojan Plasmid for Release of Anti-Tumor Shuttle Protein. Journal of Controlled Release, 2020, 320, 253-264. IF= 11.467   DOI: 10.1016/j.jconrel.2020.01.037

 

2019

77. Yan Wang#(co-first author), Xinxin Wang#(co-first author), Jing Zhang#(co-first author), Li Wang, Chunqing Ou, Yaqian Shu, Qinjie Wu, Guolin Ma*(Corresponding author)Changyang Gong*(Corresponding author). Gambogic acid-encapsulated polymeric micelles improved therapeutic effects on pancreatic cancer. Chinese Chemical Letters, 2019, 30: 885-888. IF= 8.455

76. Ning Wang#(co-first author), Chao Liu#(co-first author), Xinxin Wang, Tao He, Lu Li, Xiuqi Liang, Li Wang, Linjiang Song, Yuquan Wei, Qinjie Wu*(Corresponding author)Changyang Gong*(Corresponding author). Hyaluronic acid oligosaccharides improve myocardial function reconstruction and angiogenesis against myocardial infarction by regulation of macrophages. Theranostics, 2019, 9(7): 1980-1992. IF= 11.6

75. Jin Yang#(co-first author), Rui Tao#(co-first author), Li Wang, Linjiang Song, Yan Wang, Changyang Gong, Shaohua Yao*(Corresponding author), Qinjie Wu*(Corresponding author). Thermosensitive Micelles Encapsulating Phenylalanine Ammonia Lyase Act as a Sustained and Efficacious Therapy Against Colorectal Cancer. Journal of Biomedical Nanotechnology, 2019, 15(4): 717-727. IF= 3.641


2018

74. Lijia Luo, Chuang Liu, Tao He, Leyong Zeng, Jie Xing, Yuanzhi Zia, Yuanwei Pan, Changyang Gong*(Corresponding author), Aiguo Wu*(Corresponding author). Engineered fluorescent carbon dots as promising immune adjuvants to efficiently enhance cancer immunotherapy. Nanoscale, 2018, 10, 22035-22043. IF=8.307

73. Ling Li#(co-first author), Suleixin Yang#(co-first author), Linjiang Song, Yan Zeng, Tao He, Ning Wang, Chuan Yu, Tao Yin, Li Liu, Xiawei Wei, Qinjie Wu, Yuquan Wei, Li Yang, Changyang Gong*(Corresponding author). An Endogenous Vaccine Based on Fluorophores and Multivalent Immunoadjuvants Regulates Tumor Micro-Environment for Synergistic Photothermal and Immunotherapy. Theranostics, 2018, 8(3), 860-873. IF=11.6

72. Linjiang Song#(co-first author), Xiuqi Liang#(co-first author), Suleixin Yang, Ning Wang, Tao He, Yan Wang, Lan Zhang, Qinjie Wu, Changyang Gong*(Corresponding author). Novel polyethyleneimine-R8-heparin nanogel for high-efficiency gene delivery in vitro and in vivo. Drug Delivery, 2018, 25(1), 122-131. IF= 6.819

71. Linjiang Song#(co-first author), Anqi Zeng#(co-first author), Mingxing Hu#(co-first author), Yinchen Lin, Yaqian Shu, Xianzhou Huang, Changyang Gong, Yongmei Xie*(Corresponding author), Qinjie Wu*(Corresponding author). Biodegradable Polymeric Micelle-Mediated Delivery of a pH-Activatable Prodrug of 7-Ethyl-10-hydroxy-camptothecin (SN-38) to Enhance Anti-Angiogenesis and Anti-Tumor Activity. Journal of Biomedical Nanotechnology, 2018, 14, 268-281. IF= 3.641


2017

70. Xi Yang#(co-first author), Zhaojun Li#(co-first author), Qinjie Wu, Shouchun Chen, Cheng Yi*(Corresponding author)Changyang Gong*(Corresponding author). TRAIL and Curcumin Co-Delivery Nanoparticles Enhance TRAIL-induced Apoptosis through Upregulation of Death Receptors. Drug Delivery, 2017, 24(1), 1526-1536. IF=6.819

69. Zichao Luo#(co-first author), Qinjie Wu#(co-first author), Chengbiao Yang#(co-first author), Huaimin Wang, Tao He, HaoChen, Xingyi Li*, Changyang Gong*(Corresponding author), Zhimou Yang*(Corresponding author). A powerful CD8+ T-cell stimulating D-tetra-peptide hydrogel as a very promising vaccine adjuvant. Advanced Materials, 2017, 29(5), 1601776. IF= 32.086

68. Ling Li, Xia Li, Yuzhe Wu, Linjiang Song, Xi Yang, Tao He, Ning Wang, Suleixin Yang, Yan Zeng, Qinjie Wu, Zhiyong Qian, Yuquan Wei, Changyang Gong*(Corresponding author)Multifunctional Nucleus-targeting Nanoparticles with Ultra-high Gene Transfection Efficiency for In Vivo Gene Therapy. Theranostics, 2017, 7 (6), 1633-1649. IF= 11.6

67. Ling Li#(co-first author), Linjiang Song#(co-first author), Xiaowei Liu#(co-first author), Xi Yang#(co-first author), Xia Li, Tao He, Ning Wang, Suleixin Yang, Chuan Yu, Tao Yin, Yanzhu Wen, Zhiyao He, Xiawei Wei, Weijun Su, Qinjie Wu, Shaohua Yao*(Corresponding author), Changyang Gong*(Corresponding author), Yuquan Wei*(Corresponding author). Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice. ACS Nano, 2017, 11(1), 95-111. IF=18.027

66. Ning Wang#(co-first author), ZhiHan Wang#(co-first author), Shihong Nie#(co-first author), Linjiang Song, Tao He, Suleixin Yang, Xi Yang, Cheng Yi, Qinjie Wu*(Corresponding author), Changyang Gong. Biodegradable polymeric micelles coencapsulating paclitaxel and honokiol: a strategy for breast cancer therapy in vitro and in vivo. International Journal of Nanomedicine, 2017, 12: 1499-1514. IF=7.033


2016

65. Tao He, Chang Zou, Linjiang Song, Ning Wang, Suleixin Yang, Yan Zeng, Qinjie Wu, Wenli Zhang, Yingtai Chen*(Corresponding author), Changyang Gong*(Corresponding author). Improving anti-adhesion effect of thermosensitive hydrogel with sustained release of tissue-type plasminogen activator in a rat repeated-injury model. ACS Applied Materials & Interfaces, 2016, 8(49), 33514-33520. IF=10.383

64. Ling Li, Linjiang Song, Xi Yang, Xia Li, Yuzhe Wu, Tao He, Ning Wang, Suleixin Yang, Yan Zeng, Li Yang, Qinjie Wu, Yuquan Wei, Changyang Gong*(Corresponding author). Multifunctional “core-shell” nanoparticles-based gene delivery for treatment of aggressive melanoma. Biomaterials, 2016, 111, 124-137. IF=15.304

63. Linjiang Song#(co-first author), Ling Li#(co-first author), Tao He, Ning Wang, Suleixin Yang, Xi Yang, Yan Zeng, Wenli Zhang, Li Yang*(Corresponding author), Qinjie Wu*(Corresponding author), Changyang Gong*(Corresponding author). Peritoneal adhesion prevention with a biodegradable and injectable N,O-carboxymethyl chitosan-aldehyde hyaluronic acid hydrogel in a rat repeated-injury model. Scientific Reports, 2016, 6, 37600. IF= 4.996

62. Huaimin Wang, Zichao Luo#(co-first author), Youzhi Wang, Tao He, Chengbiao Yang, Chunhua Ren, Linsha Ma, Changyang Gong*(Corresponding author), Xingyi Li*(Corresponding author), Zhimou Yang*(Corresponding author). Enzyme-Catalyzed Formation of Supramolecular Hydrogels as Promising Vaccine Adjuvants. Advanced Functional Materials, 2016, 26 (11), 1822-1829. IF= 19.924

61. Ning Wang, Tao He#(co-first author), Yangmei Shen#(co-first author), Linjiang Song, Ling Li, Xi Yang, Xia Li, Mengru Pang, Weijun Su, Xinyu Liu*(Corresponding author), Qinjie Wu*(Corresponding author), Changyang Gong*(Corresponding author). Paclitaxel and tacrolimus co-encapsulated polymeric micelles enhance therapeutic effect of drug-resistant ovarian cancer. ACS Applied Materials & Interfaces, 2016, 8, 4368-4377. IF=10.383


2015

60. Rui Zhou, Qinjie Wu#(co-first author), MingRui Guo, Wei Huang, XiangHong He, Lei Yang, Fu Peng, Gu He*(Corresponding author), Bo Han*(Corresponding author). Organocatalytic cascade reaction for the asymmetric synthesis of novel chroman-fused spirooxindoles that potently inhibit cancer cell proliferation. Chemical Communications, 2015, 51, 13113-13116. IF=6.065

59. Lu Sun, Qinjie Wu, Feng Peng, Lei Liu, Changyang Gong*(Corresponding author). Strategies of polymeric nanoparticles for enhanced internalization in cancer therapy. Colloids and Surfaces B-Biointerfaces, 2015, 135, 56-72. IF= 5.999 

58. Qinjie Wu, Ning Wang, Tao He, Jinfeng Shang, Ling Li, Linjiang Song, Xi Yang, Xia Li, Na Luo, Wenli Zhang, Changyang Gong*(Corresponding author). Thermosensitive hydrogel containing dexamethasone micelles for preventing postsurgical adhesion in a repeated-injury model. Scientific Reports, 2015, 5, 13553.  IF=4.996

57. Wenli Zhang#, Tao Cui#, Lei Liu*,# (Corresponding author), Qinjie Wu, Lu Sun, Ling Li, Ning Wang, Changyang Gong*(Corresponding author). Improving anti-tumor activity of curcumin by polymeric micelles in thermosensitive hydrogel system in colorectal peritoneal carcinomatosis model. Journal of Biomedical Nanotechnology, 2015, 11(7), 1173-1182. IF= 3.641

56. Xi Yang, Zhaojun Li#(co-first author), Ning Wang, Ling Li, Linjiang Song, Tao He, Lu Sun, Zhihan Wang, Qinjie Wu, Na Luo, Cheng Yi*(Corresponding author), Changyang Gong*(Corresponding author). Curcumin-encapsulated polymeric micelles suppress the development of colon cancer in vitro and in vivo. Scientific Reports, 2015, 5, 10332. IF=4.996

55. Ling Li, Yuquan Wei, Changyang Gong*(Corresponding author). Polymeric nanocarriers for non-viral gene delivery. Journal of Biomedical Nanotechnology, 2015, 11(5),739-770. IF=3.641

54. Gao Xiang, Bilan Wang#(co-first author), Qinjie Wu#(co-first author), Xiawei Wei, Fengjin Zheng, Ke Men, Huashan Shi, Ning Huang, Yuquan Wei, Changyang Gong*(Corresponding author). Combined delivery and anti-cancer activity of paclitaxel and curcumin using polymeric micelles. Journal of Biomedical Nanotechnology, 2015, 11(4), 578-589. IF= 3.641

53. Senyi Deng, Qinjie Wu#(co-first author), Yuwei Zhao#(co-first author), Xin Zheng, Ni Wu, Jing Pang, Xuejing Li, Cheng Bi, Xinyu Liu, Li Yang, Lei Liu, Weijun Su, Yuquan Wei, Changyang Gong*(Corresponding author).Biodegradable polymeric micelle-encapsulated doxorubicin suppresses tumor metastasis by killing circulating tumor cells. Nanoscale, 2015, 7, 5270-5280. IF=8.307

52. Nannan Zhang, Shichang Liu#(co-first author), Ning Wang#(co-first author), Senyi Deng, Linjiang Song, Qinjie Wu, Lei Liu, Weijun Su, Yuquan Wei, Yongmei Xie*(Corresponding author), Changyang Gong*(Corresponding author). Biodegradable polymeric micelles encapsulated JK184 suppress tumor growth through inhibiting Hedgehog signaling pathwayNanoscale, 2015,7(6), 2609-2624. IF=8.307

51. Qiheng Gou, Lei Liu#(co-first author), Chunting Wang#(co-first author), Qinjie Wu, Lu Sun, Xi Yang, Yuxin Xie, Ping Li*(Corresponding author), Changyang Gong*(Corresponding author). Polymeric nanoassemblies entrapping curcumin overcome multidrug resistance in ovarian cancer. Colloids and Surfaces B-Biointerfaces, 2015, 126, 26-34. IF= 5.999

50. Yishan Chen, Qinjie Wu#(co-first author), Linjiang Song#(co-first author), Tao He, Yuchen Li, Ling Li, Weijun Su, Lei Liu* (Corresponding author), Zhiyong Qian, Changyang Gong*(Corresponding author). Polymeric micelles encapsulating fisetin improve the therapeutic effect in colon cancer. ACS Applied Materials & Interfaces, 2015, 7(1), 534-542. IF= 10.383


2014

50. Xi Yang, Cheng Yi, Na Luo, Changyang Gong*(Corresponding author). Nanomedicine to overcome cancer multidrug resistance. Current Drug Metabolism, 2014, 15(6), 632-649. IF= 3.408 

49. Qinjie Wu, Guoyou Li#(co-first author), Senyi Deng, Liang Ouyang, Ling Li, Lei Liu, Na Luo, Xiangrong Song, Gu He* (Corresponding author), Changyang Gong*(Corresponding author), Yuquan Wei. Enhanced antitumor activity and mechanism of biodegradable polymeric micelles-encapsulated chetomin in both transgenic zebrafish and mouse models. Nanoscale, 2014, 6(20): 11940-11952. IF=8.307

48. Lu Sun, Xiaohui Deng, Xi Yang, Zhaojun Li, Zhihan Wang, Ling Li, Qinjie Wu, Feng Peng, Lei Liu*(Corresponding author), Changyang Gong*(Corresponding author). Co-delivery of doxorubicin and curcumin by polymeric micelles for improving antitumor efficacy on breast carcinoma. RSC Advances, 2014, 4(87): 46737-46750.  IF=4.036

47. Wenli Zhang, Qinjie Wu#(co-first author), Ling Li, Tao Cui, Lu Sun, Ning Wang, Lei Liu*(Corresponding author), Xinyu Li, Changyang Gong*(Corresponding author). Prevention of desiccation induced postsurgical adhesion by thermosensitive micelles. Colloids and Surfaces B-Biointerfaces, 2014, 122: 309-315. IF= 5.999

46. Yuanyuan Liu, Ying Chang#(co-first author), Chao Yang#(co-first author), Zitai Sang, Tao Yang, Wei Ang, Weiwei Ye, Yuquan Wei, Changyang Gong*(Corresponding author), YoufuLuo*(Corresponding author)Biodegradable nanoassemblies of piperlongumine display enhanced anti-angiogenesis and anti-tumor activities. Nanoscale, 2014, 6, 4325-4337. IF=8.307

45Ling Li, Ning Wang, Xun Jin, Rui Deng, Shihong Nie, Lu Sun, Qinjie Wu, Yuquan Wei, Changyang Gong*(Corresponding author). Biodegradable and injectable in situ cross-linking chitosan-hyaluronic acid based hydrogel for postoperative adhesion prevention. Biomaterials, 2014, 35(12), 3903-3917. IF=15.304

44. Qinjie Wu, Ling Li, Ning Wang, Xiang Gao, Bilan Wang, Xinyu Liu, Zhiyong Qian, Yuquan Wei, Changyang Gong*(Corresponding author). Biodegradable and thermosensitive micelles inhibit ischemic-induced postoperative peritoneal adhesion. International Journal of Nanomedicine, 2014, 9(1), 727-734. IF=7.033

43. Xi Yang, Dan Cao#(co-first author), Ning Wang, Lu Sun, Ling Li, Shihong Nie, Qinjie Wu, Xinyu Liu, Cheng Yi*(Corresponding author), Changyang Gong*(Corresponding author)In vitro and in vivo safety evaluation of biodegradable self-assembled monomethyl poly (ethylene glycol)–poly (ε-caprolactone)–poly (trimethylene carbonate) micellesJournal of Pharmaceutical Sciences, 2014, 103(1): 305-313. IF= 3.784

42. Shasha He, Qinjie Wu#(co-first author), Changyang Gong#(co-first author), Shuntao Luo, Shuang Zhang, Meng Li, Lin Lu, Yuquan Wei, Li Yang* (Corresponding author). Enhanced efficacy of combination therapy with adenoassociated virus-delivered pigment epithelium-derived factor and cisplatin in a mouse model of Lewis lung carcinoma. Molecular Medicine Reports, 2014, 9(6): 2069-2076. IF= 3.423


2013

41. Qinjie Wu, Senyi Deng#(co-first author), Ling Li, Lu Sun, Xi Yang, Xinyu Liu, Lei Liu, Zhiyong Qian, Yuquan Wei, Changyang Gong*(Corresponding author)Biodegradable polymeric micelle-encapsulated quercetin suppresses tumor growth and metastasis in both transgenic zebrafish and mouse models. Nanoscale, 2013, 5(24): 12480-12493. IF=8.307

40. Xiang Gao, Xiaohui Deng, Xiawei Wei, Huashan Shi, Fengtian Wang, Tinghong Ye, Bin Shao, Wen Nie, Yuli Li, Min Luo, Changyang Gong*(Corresponding author), Ning Huang*(Corresponding author). Novel thermosensitive hydrogel for preventing formation of abdominal adhesions. International Journal of Nanomedicine, 2013, 8: 2453-2463. IF=7.033

39. Qida Long, Yao Xie#(co-first author), Yanqing Huang, Qinjie Wu, Hecheng Zhang, Shaoquan Xiong, Yingwei Liu, Lijuan Chen, Yuquan Wei, Xia Zhao*(Corresponding author), Changyang Gong*(Corresponding author)Induction of apoptosis and inhibition of angiogenesis by PEGylated liposomal quercetin in both cisplatin-sensitive and cisplatin-resistant ovarian cancers. Journal of Biomedical Nanotechnology, 2013, 9: 965-975. IF= 3.641

38. Lei Liu, Qinjie Wu#(co-first author), Xuelei Ma, Dake Xiong, Changyang Gong*(Corresponding author), Zhiyong Qian, Xia Zhao, Yuquan Wei. Camptothecine encapsulated composite drug delivery system for colorectal peritoneal carcinomatosis therapy: Biodegradable microsphere in thermosensitive hydrogel. Colloids and Surfaces B-Biointerfaces, 2013, 106: 93-101. IF= 5.999

37. Lei Liu, Lu Sun#(co-first author), Qinjie Wu#(co-first author), Wenhao Guo, Ling Li, Yishan Chen, Yuchen Li, Changyang Gong*(Corresponding author), Zhiyong Qian, Yuquan Wei. Curcumin loaded polymeric micelles inhibit breast tumor growth and spontaneous pulmonary metastasis. International Journal of Pharmaceutics, 2013, 443(1-2): 175-182. IF=6.51

36. Changyang Gong*(Corresponding author), Senyi Deng#(co-first author), Qinjie Wu#(co-first author), Mingli Xiang, Xiawei Wei, Ling Li, Xiang Gao, Bilan Wang, Lu Sun, Yishan Chen, Yuchen Li, Lei Liu, Zhiyong Qian, Yuquan Wei. Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles. Biomaterials, 2013, 34: 1413-1432. IF= 15.304

35. Changyang Gong, Qinjie Wu, JinFeng Liao, Tingting Qi, Bing Yang, Yujun Wang, Gang Guo, Feng Luo, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Prevention of postsurgical cauterization-induced peritoneal adhesions by biodegradable and thermosensitive micelles. Journal of Biomedical Nanotechnology, 2013, 9: 1984-1995. IF= 3.641

34. Changyang Gong, Qinjie Wu, Yujun Wang, Doudou Zhang, Feng Luo, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). A biodegradable hydrogel system containing curcumin encapsulated in micelles for cutaneous wound healing. Biomaterials, 2013, 34(27): 6377-6387. IF=15.304

33. Changyang Gong, Tingting Qi, Xiawei Wei, Ying Qu, Qinjie Wu, Feng Luo, Zhiyong Qian*(Corresponding author). Thermosensitive polymeric hydrogels as drug delivery systems. Current Medicinal Chemistry, 2013, 20(1): 79-94. IF= 4.74

32. Changyang Gong, Tao Yang#(co-first author), Xiaoyan Yang, Yuanyuan Liu, Wei Ang, Jianying Tang, Weiyi Pi, Li Xiong, Ying Chang, Weiwei Ye, Zhenling Wang*(Corresponding author), Youfu Luo*(Corresponding author), Xia Zhao, Yuquan Wei. Carrier-free nanoassemblies of a novel oxazolidinone coumpound FYL-67 display antimicrobial activity on methicillin-resistant Staphylococcus aureus. Nanoscale, 2013, 5: 275-283. IF=8.307


2012

31. Yao Xie, Qida Long#(co-first author), Qinjie Wu, Shuai Shi, Mei Dai, Yingwei Liu, Lei Liu, Changyang Gong*(Corresponding author), Zhiyong Qian, Yuquan Wei, Xia Zhao*(Corresponding author). Improving therapeutic effect in ovarian peritoneal carcinomatosis with honokiol nanoparticles in a thermosensitive hydrogel composite. RSC Advances, 2012, 2 (20): 7759 - 7771. IF=4.036

30. Changyang Gong*(Corresponding author), Yongmei Xie#(co-first author), Qinjie Wu, Yujun Wang, Senyi Deng, Dake Xiong, Lei Liu, Mingli Xiang*(Corresponding author), Zhiyong Qian, Yuquan Wei. Improving anti-tumor activity with polymeric micelles entrapping paclitaxel in pulmonary carcinoma. Nanoscale, 2012, 4: 6004-6017. IF=8.307

29. Qiongwen Zhang, Lei Liu#,*(co-first author, Corresponding author), Changyang Gong#(co-first author), Huashan Shi, Yunhui Zeng, Xiaoze Wang, Yuwei Zhao, Yuquan Wei. Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor-A Meta-Analysis of the Literature. PLoS ONE, 2012, 7(12): e50946.  IF=3.752

28. Na Lei, Changyang Gong#(co-first author), Zhiyong Qian*(Corresponding author), Feng Luo*(Corresponding author), Cheng Wang, Helan Wang, Yuquan Wei. Therapeutic application of injectable thermosensitive hydrogel in preventing local breast cancer recurrence and improving incision wound healing in a mouse model. Nanoscale, 2012, 4:5686-5693. IF=8.307

27. Huashan Shi, Changyang Gong#(co-first author), Hailong Zhang, Yongsheng Wang*(Corresponding author), Jing Zhang, Zichao Luo, Zhiyong Qian, Yuquan Wei, Li Yang*(Corresponding author). Novel vaccine adjuvant LPS-Hydrogel for truncated basic fibroblast growth factor to induce antitumor immunity. Carbohydrate Polymers, 2012, 89(4): 1101-1109.  IF= 10.723

26. Jing Li, Changyang Gong#(co-first author), Xiaodong Feng, Xikun Zhou, Xiaoping Xu, Liang Xie, Ruinan Wang, Dunfang Zhang, Hui Wang, Peng Deng, Min Zhou, Ning Ji, Yu Zhou, Yun Wang, Zhiyong Wang, Ga Liao, Ning Geng, Liangyin Chu, Zhiyong Qian*(Corresponding author), Zhi Wang*(Corresponding author), Qianming Chen*(Corresponding author). Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: Therapeutic effects on oral squamous cell carcinoma xenografts. PLoS ONE, 2012, 7(4): e33860. IF=3.752 

25. Qinjie Wu, Changyang Gong#(co-first author), Shuntao Luo, Dongmei Zhang, Shuang Zhang, Huashan Shi, Lian Lu, Hengxiu Yan, Shasha He, Dandan Li, Li Yang*(Corresponding author), Xia Zhao, Yuquan Wei. AAV-mediated human PEDF inhibits tumor growth and metastasis in murine colorectal peritoneal carcinomatosis model. BMC Cancer, 2012, 12: 129. IF= 4.638

24. Bing Yang, Changyang Gong#(co-first author), Xia Zhao, Shengtao Zhou, Zhengyu Li, Xiaorong Qi, Qian Zhong, Feng Luo, Zhiyong Qian*(Corresponding author). Preventing postoperative abdominal adhesions in a rat model with PEG-PCL-PEG hydrogel. International Journal of Nanomedicine, 2012, 7: 547-557. IF=7.033

23. Changyang Gong, Bing Yang, Zhiyong Qian*(Corresponding author), Xia Zhao, Qinjie Wu, Xiaorong Qi, Yujun Wang, Gang Guo, Bing Kan, Feng Luo, Yuquan Wei. Improving intraperitoneal chemotherapeutic effect and preventing postsurgical adhesions simultaneously with biodegradable micelles. Nanomedicine-Nanotechnology Biology and Medicine, 2012, 8(6): 963-973. IF= 6.458

22. Changyang Gong, Cheng Wang, Yujun Wang, Qinjie Wu, Doudou Zhang, Feng Luo, Zhiyong Qian*(Corresponding author). Efficient inhibition of colorectal peritoneal carcinomatosis by drug loaded micelles in thermosensitive hydrogel composites. Nanoscale, 2012, 4: 3095-3104. IF=8.307


2011

21. Qinjie Wu#(co-first author), Xuechen Zhu#(co-first author), Xiong Xiao, Pan Wang, Dake Xiong, Changyang Gong*(Corresponding author), Yongsheng Wang, Li Yang, Yuquan Wei. A novel vaccine delivery system: Biodegradable nanoparticles in thermosensitive hydrogel. Growth Factors, 2011, 29(6): 290-297. IF=2.394

20. Bing Yang, Changyang Gong#(co-first author), Zhiyong Qian*(Corresponding author), Xia Zhao*(Corresponding author), Zhengyu Li, Shengtao Zhou, Xiaorong Qi, Qian Zhong, Feng Luo, Yuquan Wei. Prevention of abdominal adhesion formation by thermosensitive PECE-hydrogel in a rat uterine horn model. Journal of Biomedical Materials Research Part B-applied, 2011, 96B(1): 57-66. IF= 3.405 

19. Changyang Gong, Yujun Wang, Xiuhong Wang, Xiawei Wei, Qinjie Wu, Bilan Wang, Pengwei Dong, Lijuan Chen*(Corresponding author), Feng Luo, Zhiyong Qian*(Corresponding author). Biodegradable self-assembled PEG-PCL-PEG micelles for hydrophobic drug delivery, part 2: in vitro and in vivo toxicity evaluation. Journal of Nanoparticle Research, 2011, 13(2): 721-731. IF= 2.533


2010 and before

18.Yongsheng Wang*(Corresponding author), Changyang Gong#(co-first author), Li Yang, Qinjie Wu, Shuai Shi, Huashan Shi, Zhiyong Qian*(Corresponding author), Yuquan Wei. 5-Fu-hydrogel inhibits colorectal peritoneal carcinomatosis and tumor growth in mice. BMC Cancer, 2010, 10: 402. IF= 4.638

17. Maling Gou, Changyang Gong#(co-first author), Juan Zhang#(co-first author), Xiuhong Wang, Xianhuo Wang, Yingchun Gu, Gang Guo, Lijuan Chen, Feng Luo, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Polymeric matrix for drug delivery: Honokiol-loaded PCL-PEG-PCL nanoparticles in PEG-PCL-PEG thermosensitive hydrogel. Journal of Biomedical Materials Research Part A, 2010, 93A(1): 219-226. IF=4.854

16. HongBo Yin, Changyang Gong#(co-first author), Shuai Shi, Xuyang Liu*(Corresponding author), Yuquan Wei, Zhiyong Qian*(Corresponding author). Toxicity evaluation of biodegradable and thermosensitive PEG-PCL-PEG hydrogel as a potential in situ sustained ophthalmic drug delivery system. Journal of Biomedical Materials Research Part B-applied, 2010, 92B(1): 129-137. IF= 3.405

15. Changyang Gong, Xiawei Wei, Xiuhong Wang, Yujun Wang, Gang Guo, Yongqiu Mao, Feng Luo, Zhiyong Qian*(Corresponding author). Biodegradable self-assembled PEG–PCL–PEG micelles for hydrophobic honokiol delivery: I. Preparation and characterization. Nanotechnology, 2010, 21: 215103. IF= 3.953

14. Fang Fang, Changyang Gong#(co-first author), Zhiyong Qian#,*(co-first author, Corresponding author), Xiaoning Zhang, Maling Gou, Chao You, Liangxue Zhou, Jiagang Liu, Yu Zhang, Gang Guo, Yingchun Gu, Feng Luo, Lijuan Chen, Xia Zhao, Yuquan Wei. Honokiol Nanoparticles in Thermosensitive Hydrogel: Therapeutic Effects on Malignant Pleural Effusion. ACS Nano, 2009, 3(12): 4080-4088. IF=18.027

13. Fang Fang, Changyang Gong#(co-first author), Pengwei Dong#(co-first author), Shaozhi Fu, Yingchun Gu, Gang Guo, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Acute toxicity evaluation of in situ gel-forming controlled drug delivery system based on biodegradable poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) copolymer. Biomedical Materials, 2009, 4(2): 025002. IF=4.103

12. Changyang Gong, Shuai Shi, Xinyun Peng, Bing Kan, Li Yang*(Corresponding author), Meijuan Huang, Feng Luo, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Biodegradable thermosensitive injectable PEG-PCL-PEG hydrogel for bFGF antigen delivery to improve humoral immunity. Growth Factors, 2009, 27(6): 377–383. IF=2.394

11. Changyang Gong, Shuai Shi, Pengwei Dong, Bing Yang, Xiaorong Qi, Gang Guo, Yingchun Gu, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PCL-PEG-PCL hydrogel: part 1-synthesis, characterization, and acute toxicity evaluation. Journal of Pharmaceutical Sciences, 2009, 98(12): 4684-4694. IF= 3.784

10. Changyang Gong, Shuai Shi, Lan Wu, Maling Gou, QinQin Yin, Qingfa Guo, Pengwei Dong, Fan Zhang, Feng Luo, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PCL-PEG-PCL hydrogel. Part 2: Sol-gel-sol transition and drug delivery behavior. Acta Biomaterialia, 2009, 5(9): 3358-3370. IF=10.633

9. Changyang Gong, Qinjie Wu#(co-first author), Pengwei Dong, Shuai Shi, Shaozhi Fu, Gang Guo, Huozhen Hu, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Acute toxicity evaluation of biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PEG-PCL-PEG hydrogel. Journal of Biomedical Materials Research Part B-applied, 2009, 91B(1): 26-36. IF= 3.405

8. Changyang Gong, Pengwei Dong#(co-first author), Shuai Shi, Shaozhi Fu, Jinliang Yang, Gang Guo, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Thermosensitive PEG-PCL-PEG hydrogel controlled drug delivery system: Sol-Gel-Sol transition and in vitro drug release study. Journal of Pharmaceutical Sciences2009, 98(10): 3707-3717. IF= 3.784

7. Changyang Gong, Shuai Shi, Xiuhong Wang, Yujun Wang, Shaozhi Fu, Pengwei Dong, Lijuan Chen, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Novel composite drug delivery system for honokiol delivery: self-assembled poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) micelles in thermosensitive poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) hydrogel. Journal of Physical Chemistry B, 2009, 113 (30): 10183–10188. IF= 3.466

6. Changyang Gong, Shaozhi Fu#(co-first author), Yingchun Gu#(co-first author), Caibing Liu, Bing Kan, Hongxin Deng, Feng Luo, Zhiyong Qian*(Corresponding author). Synthesis, characterization, and hydrolytic degradation of biodegradable poly(ether ester)-urethane copolymers based on ε-caprolactone and poly(ethylene glycol). Journal of Applied Polymer Science, 2009, 113(2): 1111-1119. IF= 3.057

5. Changyang Gong, Shuai Shi, Pengwei Dong, Xiuling Zheng, Shaozhi Fu, Gang Guo, Jingliang Yang*(Corresponding author), Yuquan Wei, Zhiyong Qian*(Corresponding author). In vitro drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) copolymer. BMC Biotechnology, 2009, 9:8.  IF= 3.329

4. Changyang Gong, Shuai Shi#(co-first author), Pengwei Dong, Bing Kan, Maling Gou, Xianhuo Wang, Xingyi Li, Feng Luo, Xia Zhao, Yuquan Wei, Zhiyong Qian*(Corresponding author). Synthesis and Characterization of PEG-PCL-PEG Thermosensitive Hydrogel. International Journal of Pharmaceutics, 2009, 365(1-2): 89-99.  IF= 6.51

3. Caibing Liu, Changyang Gong#(co-first author), Meijuan Huang#(co-first author), Jiwei Wang, Yifeng Pan, YangDe Zhang, Guozheng Li, Maling Gou, Ke Wang, Mingjing Tu, Yuquan Wei, Zhiyong Qian#,*(co-first author, Corresponding author). Thermoreversible gel-sol behavior of biodegradable PCL-PEG-PCL triblock copolymer in aqueous solutions. Journal of Biomedical Materials Research Part B-applied, 2008, 84B(1): 165-175. IF= 3.405

2. Caibing Liu, Changyang Gong#(co-first author), Yifeng Pan#(co-first author), Yangde Zhang, Jiwei Wang, Meijuan Huang, Yongsheng Wang, Ke Wang, Maling Gou, Mingjing Tu, Yuquan Wei, Zhiyong Qian*(Corresponding author). Synthesis and characterization of a thermosensitive hydrogel based on biodegradable amphiphilic PCL-Pluronic(L35)-PCL block copolymers. Colloids and Surfaces A-physicochemical and Engineering Aspects, 2007, 302(1-3): 430-438. IF= 5.518

1. Changyang Gong, Zhiyong Qian#,*(co-first author, Corresponding author), Caibing Liu#(co-first author), Meijuan Huang#(co-first author), Yingchun Gu, Yanjun Wen, Bing Kan, Ke Wang, Mei Dai, Xingyi Li, Maling Gou, Mingjing Tu, Yuquan Wei. A thermosensitive hydrogel based on biodegradable amphiphilic poly(ethylene glycol)-polycaprolactone-poly(ethylene glycol) block copolymers. Smart Materials and Structures, 2007, 16(3): 927-933.  IF= 4.131