Cover stories
Biomaterials Science (2020)
Publications (# Equal contribution, * Corresponding author）
2021
52. Q. Xiao*, X. Dong, F. Yang, S. Zhou, M. Xiang, L. Lou, S.Q. Yao*，L. Gao*, “Engineered Cell-penetrating Peptides for Mitochondria-targeted Delivery in Cancer Therapy”, (2021), submitted.
51. X. Dong, S. Y. Ong, C. Zhang, W. Chen, S. Du, Q. Xiao, L. Gao, S. Q. Yao*, “Broad-Spectrum Polymeric Nanoquencher as An Efficient Fluorescence Sensing Platform for Biomolecular Detection”, ACS Sensors (2021), submitted.
50. P. Yuan*#, S.S. Liew#, J. Yan, F. Yang, X. Dong, J. Wang, S. Du, X. Mao, L. Gao, Shao Q. Yao*, “Intracellular Co-delivery of Native Antibody and siRNA for Combination Therapy by Using Biodegradable Silica Nanocapsules”, Advanced Functional Materials (2021), submitted.
49. Y. Liu, S. Lv, L. Peng, C. Xie, L. Gao, H. Sun, L. Lin, K. Ding,*Z. Li*, “Development and Application of Novel Electrophilic Warheads in Target Identification and Drug Discovery ”, Biochemical Pharmacology (2021), 190, 2114636.
48. Q. Xiao#, W. Du#, X. Dong, S. Du, S.Y. Ong, G. Tang, C. Zhang, F. Yang, L. Li*, L. Gao*, S.Q. Yao*, “Cell-penetrating mitochondria-targeting ligands for universal delivery of small molecules, proteins and nanomaterials”, Chem. Eur. J. (2021), in press DOI:10.1002/chem.202101989.
47. W.J. Shi*, L., Feng, X. Wang, Y. Huang, Y.F. Wei, Y.Y. Huang, H.J. Ma, L. Zheng, L. Gao*, “A near-infrared-emission aza-BODIPY-based fluorescent probe for fast, selective, and “turn-on”detection of HClO and ClO-”, Talanta (2021) , 233,122581.
46. M. Xiang#, Q. Zhou#, Z. Shi, X. Wang, M. Li, Y. Jia, S. Li, F. Yang, W. Wang, T. Chen, X. Xu, B. Sharma, Y. Nie, Q. Xiao*, L. Gao*, “A review of light sources and enhanced targeting for photodynamic therapy”, Current Medicinal Chemistry (2021), DOI: 10.2174/0929867328666210121122106.
45. Y. Mo#, L. Duan#, Y. Yang, W. Liu, Y. Zhang, L. Zhou, S. Su, P.C. Lo, J. Cai, L. Gao, Q. Liu, X. Chen, C. Yang*, Q. Wang*, T. Chen*, “Nanoparticles Improved Resveratrol Brain Delivery and its Therapeutic Efficacy against Intracerebral Hemorrhage”, Nanoscale (2021), 13(6), 3827-3840.)
44. Q. Xiao, B. Mai, Y. Nie, C. Yuan, M. Xiang, Z. Shi, J. Wu, W.A. Leung, C.S. Xu*, S.Q. Yao*, P. Wang*, L. Gao*, “In Vitro and In Vivo Demonstration of Ultra-Efficient and Broad-Spectrum Antibacterial Agents for Photodynamic Antibacterial
Chemotherapy", ACS Applied Materials & Interfaces (2021), 13(10):11588-11596. (IF 8.758 in 2020, 中科院1区，Top journal)
43. S. Xiong, J.S. Luo, Q. Wang, Z.J. Li, J.T. Li, Q. Liu, L. Gao, S. Fang, Y. Li, H. Pan, H. Wang, Y. Zhang, Q. Wang, X. Chen*, T. Chen* “Targeted Graphene Oxide for Drug Delivery as a Therapeutic Nanoplatform against Parkinson’s Disease”, Biomaterials Science (2021), 9(5), 1705-1715.
42. L. Gao*, #, W. Wang#, X. Wang#, F. Yang, L. Xie, J. Shen, M.A. Brimble, Q. Xiao*, S. Q. Yao*, “Fluorescent probes for bioimaging of potential biomarkers in Parkinson’s disease”, Chem. Soc. Rev. (2021), 50(2), 1219-1250. (IF 42.846 in 2020, 中科院1区，Top journal)
2020
41. L. Lu, Q. Zhang, Z. Wang, L. Gao*, J. Shen*, “Peptide-Modified Nanoparticles for Tumour Targeting and Molecular Imaging”, Current Medicinal Chemistry (2020), DOI: 10.2174/0929867327666201022122131. (IF 4.184)
40. Y. Liu, D.M. Zhu, J. Luo, X. Chen, L. Gao, W. Liu*, T. Chen*, “NIR-II-Activated Yolk-Shell Nanostructures as an Intelligent Platform for Parkinsonian Therapy”, ACS Applied Bio Materials (2020), 3(10), 6876-6887.
39. Y. Wu#, L. Wang#, Y. Xiong#, Q. Zhou, L. Li, G. Chen, Y. Ping, G. Davidson, P.A. Levkin*, L. Gao*, W. Deng*, “Cell-based high-throughput screening of cationic polymers for efficient DNA and siRNA delivery”, Acta Biomaterialia (2020), 115, 410-417. (IF 7.242 in 2020, 中科院1区，Top journal)
38. B. Sharma#, L. Xie#, F. Yang#, W. Wang#, Q. Zhou, M. Xiang, S. Zhou, W. Lv, Y. Jia, L. Pokhrel, J. Shen, Q. Xiao*, L. Gao*, W. Deng*,“Recent advance on PTP1B inhibitors and their biomedical applications”, European Journal of Medicinal Chemistry (2020), 199:112376, doi:10.1016/j.ejmech.2020.112376. (IF 5.572 in 2020, 中科院1区，Top Journal)
37. Q. Xiao, H. Lin, J. Wu, X. Pang, Q. Zhou, Y. Jiang, P. Wang, A. W. Leung, H. Lee, S. Jiang, S.Q. Yao, L. Gao*, G. Liu*, C.-S. Xu*, “Pyridine Embedded Phenothiazinium Dyes as Lysosome-Targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy”, Journal of Medicinal Chemistry (2020), 63(9), 4896-4907. (IF 6.205 in 2020, 中科院1区，Top journal)
36. Y. Wu#, Y. Xiong#, L. Wang#, Q. Zhou, L. Li, P.A. Levkin, G. Davidson*, L. Gao*, W. Deng*, “Development of new self-assembled cationic amino liposomes for efficient gene delivery”, Biomaterials Science (2020), 8, 3021-3025. (Selected as back cover) (IF 6.183 in 2020, 中科院2区)
2019
35. J. Ding#, J. Chen#, L. Gao#, Z. Jiang, Y. Zhang, M. Li, Q. Xiao, S.S. Lee*, X. Chen*, “Engineered nanoplatforms for enhanced tumor penetration”, Nano Today (2019), 100800, DOI:10.1016/j.nantod.2019.100800.(Most downloaded paper since Dec of 2019 in Nano Today)
34. L. Gao*, S. S. Lee*, H. Sun*, J. Wang*, “Editorial: Recent Advances in Strategies and Tools for Efficient Drug Discovery and Delivery”, Current Medicinal Chemistry (2019), 26(13), 2232-2233.
33. Q. Xiao#, W. Zhu#, W. Feng#, S. S. Lee, A.W. Leung, J. Shen*, L. Gao*, C. Xu*, “A Review of Resveratrol as a Potent Chemoprotective and Synergistic Agent in Cancer Chemotherapy”, Frontiers in Pharmacology (2019), 9:1534. DOI:10.3389/fphar.2018.01534.
2018
32. J. Wang, L. Qiu, Y. You, L. Ma, Z. Zhu, L. Yang, J. Wang, X. Wang*, L. Liu, X. Liu, Y. Chang, J. Li, L. Gao*, and Y.-Q. Li*, “A novel in-capillary assay for dynamically monitoring fast binding between antibody and peptides using CE”, Journal of Separation Science （2018）41(24), 4544-4550.
31. J. Wang, Z. Zhu, L. Qiu, J. Wang, X. Wang*, Q. Xiao, J. Xia, L. Liu, X. Liu, W. Feng, J. Wang, P. Miao*, L. Gao*, “A CE-FL based method for real time detection of in-capillary self-assembly of the nanoconjugates of polycysteine ligand and quantum dots”, Nanotechnology (2018), 29(27), 274001, DOI:10.1088/1361-6528/aabe5d.
30. W. Feng, T. Huang, L. Gao, X. Yang, W. Deng, R. Zhou*, H. Liu*, “Textile supported silver nanoparticles as a highly efficient and recyclable heterogeneous catalyst for nitroaromatics reduction at room temperature”, RSC Advances (2018), 8，6288-6292.
2017
27. C. Guo*, J. Zhong, L. Gao, J. Gao, S. Huang，Editorial: Thematic Issue: Nanostructures for Flexible Electronics and Drug Delivery, (2017), Journal of Nanomaterials, 2017, 3516952-1--3516952-2, DOI: 10.1155/2017/3516952.
26. Q. Xiao, J. Wu, X. Pang, Y. Jiang, W. A. Leung, L. Gao, S. Jiang, C. Xu*, “Discovery and Development of Natural Products as Photosensitizers for Photodynamic Therapy”, Current Medicinal Chemistry (2018), 25(7), 839-860.
25. J. Wang, J. Fan, L. Liu, S. Ding, X. Liu, L. Gao*, S. Chattopadhaya, P. Miao, J. Xia, L. Qiu*, P. Jiang*, “Developing a capillary electrophoresis based method for dynamically monitoring enzyme cleavage activity using quantum dots-peptide assembly”, Electrophoresis (2017), 38(19), 2530-2535.
(Publications before joining SYSU in 2017)
24. Y.S. Ong#, L. Gao#, K.A. Kalesh, Z. Yu*, J. Wang, C. Liu, Y. Li, H. Sun*, S.S. Lee*, “Recent Advances in Synthesis, Identification and Bioapplications of Bioactive peptides”, (2017), Current Topics in Medicinal Chemistry,17(2017), 2302-2318.
23. W. Liao#, T.-T. Zhang #, L. Gao, S. S. Lee, J. Xu, H. Zhang, Z.G. Yang, Z. Liu,*, W. Li*, “Integration of Novel Materials and Advanced Genomic Technologies into New Vaccine Design”, (2017), Current Topics in Medicinal Chemistry, 17(2017), 2286-2301.
2016
22. P. Wang#, L. Gao#, H. Lei, S.S. Lee*, S.Q. Yao, H. Sun*. “A Versatile Microarray Immobilization Strategy Based on a Biorthogonal Reaction Between Tetrazine and Trans-cyclooctene”, Methods in Molecular Biology,1518 (2017), 67-80.
21. J.H. Wang, C. Zhang, L. Liu, L. Qiu, S. Ding, M. Fu, L. Gao* and P. Jiang*,"A capillary electrophoresis method to explore the self-assembly of a novel polypeptide ligand with quantum dots”, (2016), Electrophoresis, 37(15-16), 2156-2162.
19. J. Wang, J. Li, J.C. Li, F. Liu, Y. Gu, J. Fan, B. Dong, C. Wang, L. Qiu*, L. Gao*, S. S. Lee*, P. Jiang*, “Organic Chemistry Tool for Nanoparticles Monofunctinalization and Their Biomedical Applications”, (2016), Current Organic Chemistry, 20 (17), 1786-1796.
18. J.-E. Jee, J. Lim, Y. S. Ong, J. Oon, L. Gao, H.S. Choi, S.S. Lee, “An Efficient Strategy to Enhance Binding Affinity and Specificity of a Known Isozyme Inhibitor with Moderate Binding Affinity”, (2016), Organic & Biomolecular Chemistry, 14(28), 6833-6839.
17. F. Liu, J.H. Wang*, L. Liu, S. Ding, M. Fu, L. Deng* and L. Gao*, “Developing a fluorescence coupled capillary electrophoresis based method to probe interactions between QDs and colorectal cancer targeting peptides”, (2016), Electrophoresis, 37(15-16), 2170-2174.
16. J. Wang*, #, L. Gao#, Y. M. Lee#, K.A. Kalesh, Y.S. Ong, J. Lim, J.-E. Jee, H. Sun, S.S. Lee*, Z-C Hua*, Q.S. Lin *, “Target identification of natural and traditional medicine with quantitative chemical proteomics approaches”, Pharmacology & Therapeutics, 162 (2016), 10-22.
15. P. Miao*, Y. Tang, B. Wang, C. Jiang, L. Gao, B. Bo, J. Wang*, “Nuclease assisted target recycling and spherical nucleic acids gold nanoparticles recruitment for ultrasensitive detection of microRNA”, (2016), Electrochimica Acta,190, 396-401.
2015
14. L. Gao, S.S. Lee, J. Chen, H. Sun*, Y. Zhao, Z. Chai, Y. Hu*, “High-throughput Screening of Substrate Specificity for Protein Tyrosine Phosphatases (PTPs) on Phosphopeptide Microarrays”, Methods in Molecular Biology, 1368 (2016), 181-196.
13. Z. Yu #, B. Yan #, L. Gao, C. Dong, J. Zhong, M. D'Ortenzio, B. Nguyen, S.S. Lee, X. Hu*, F. Liang*,“Targeted delivery of Bleomycin: a comprehensive anticancer review”. Current Cancer Drug Target, (2016), 16 (6), 509-521.
12. R. Peltier, G. Chen, H, Lei, M. Zhang, L. Gao, S.S. Lee, Z. Wang, H. Sun, “Rational Design of Peptide based Hydrogel Responsive to H2S”, Chem. Commun., 51 (97) (2015), 17273-17276.
11. Z. Yu#, Q. Xu#, C.B. Dong, S.S. Lee, L. Gao*,Y. Li, M. D’Ortenzio, J. Wu*,” Self-assembling peptide nanofibrous hydrogel as a versatile drug delivery platform”, Current Pharmaceutical Design, 21(29) (2015), 4342-4354.
10. L. Gao#, Z. Yu#, D. Meng, F. Zheng, Y.S. Ong, P. Miao*, S.S. Lee*, L.P. Wen*, “Analogue of Melanotan II (MTII): A Novel Melanotropin with Superpotent Action on Frog Skin”, Protein and Peptide Letters, 22(2015), 762-766.
2014
9. J. Chen#,*, X.J. Li#, L. Gao, Y. Hu*, W. Zhong, M. Xing*, “A Facile Strategy for In-Situ Controlled Delivery of Doxorubicin With a pH-Sensitive Injectable Hydrogel”, Nano LIFE, 4 (2014), 1441001-1—1441001-13.
8. D. Ling#, L. Gao #, J. Wang #, M. Shokouhimehr, J. Liu, Y. Yu, M. J. Hackett, P.K. So, B. Zheng, Z. Yao, J. Xia*, and T. Hyeon*, “A General Strategy for Site-directed Enzyme Immobilization using NiO Nanoparticle Decorated Mesoporous Silica”, Chemistry-A European Journal, 20 (2014), 7916–7921.
2013
7. J. Wang#, P. Jiang#, L. Gao, Y. Yu, Y. Lu, L. Qiu, C. Wang, and J. Xia*, “Unique Self-assembly Properties of a Bridge-Shaped Protein Dimer with Quantum Dots”, Journal of Nanoparticle Research, 15 (2013), 1914-1919.
6. L. Gao, H. Sun, M. Uttamchandani*, and S.Q. Yao*, “Phosphopeptide Microarrays for Comparative Proteomic Profiling of Cellular Lysates”, Methods in Molecular Biology,1002 (2013), 233-251.
Before 2013
5. L. Gao, M. Uttamchandani*, and S.Q. Yao*, “Comparative Proteomic Profiling of Mammalian Cell Lysates Using Phosphopeptide Microarrays”, Chem. Commun., 48 (2012), 2240-2242.
4. L. Gao, H. Sun, and S.Q. Yao*, “Activity-Based High-Throughput Determination of PTPs Substrate Specificity Using a Phosphopeptide Microarray”, Biopolymers, 94 (2010), 810–819.
3. K.A. Kalesh, L.P. Tan, K. Liu, L. Gao, J. Wang, and S.Q. Yao*, “Peptide-based Activity-Based Probes (ABPs) for Target-Specific Profiling of Protein Tyrosine Phosphatases (PTPs)”, Chem. Commun., 46 (2010), 589-591.
2. H. Sun, L.P. Tan, L. Gao, and S.Q. Yao*, “High-Throughput Screening of Catalytically Inactive Mutants of Protein Tyrosine Phosphatases (PTPs) in a Phosphopeptide Microarray”, Chem. Commun., [6] (2009), 677-679.
1. H. Sun, C.H.S. Lu, H. Shi, L. Gao, and S.Q. Yao*, “Peptide Microarrays for High-throughput Studies of Ser/Thr Phosphatases”, Nature Protocols, 3 (2008), 1485-1493.
专利
12. 高理钱， 石子寒，杨芬，肖奇才、谢刘幸、贾艳、李少云、张达, “靶向干扰素γ的多肽及其应用”，中国发明专利申请号：CN202011423132.7, 申请日2020年12月9日
11. 高理钱，谢刘幸，谈思佳，王璇，李孟础，杨芬，贾艳，肖奇才，沈君，“靶向PKM2蛋白的抗肿瘤多肽及其引用”，中国发明专利申请号：CN202011355591.6, 申请日 2020年11月27日
10. 高理钱，贾艳，肖奇才，杨芬，谢程亮, “一种抗敏组合物及其制备方法和应用”，中国发明专利申请号：CN202010926658.0, 申请日 2020年9月7日
9. 高理钱，李少云，张达，石子寒，杨芬，肖奇才，周士哲，吕婉婷，李晗玥，“靶向BRD4蛋白的抗肿瘤多肽及其应用”, 中国发明专利申请号: CN202010996282.0, 申请日2020年9月22日
8. 高理钱，谢刘幸，李孟础，王璇，汪伟，肖奇才，杨芬，沈君，邓文斌，“靶向GRB2 SH2 结合域的抗肿瘤多肽及其应用”,中国发明专利申请号：CN201911258905.8, 申请日 2019年12月10日,公开日2020年4月10日
7.肖奇才，高理钱，周全明，石子寒，汪伟，向梦华，谢刘幸，杨芬，罗川朝。“一种氟替卡松丙酸酯中间体的制备方法”。中国发明专利申请号：CN202010150457.6,申请日2020年03月06日,公开日2020年06月19日
6.肖奇才，尹国建，高理钱，向梦华。“一种激光器”。中国发明专利申请号：CN202010151860.0, 申请日2020年03月06日,公开日 2020年6月26日
5.肖奇才，尹国建，高理钱，向梦华。“一种激光器”。中国实用新型专利申请号：CN202020273439.2, 申请日2020年03月06日,授权公
告日：2020年10月9日，专利号ZL202020273439.2 (已授权)
4. 彭锦安，李方林，张琦珊，肖奇才，冯伟，高理钱, “一种米索前列醇酸的制备方法及其用途”, 中国发明专利申请号: 201810308887.9, 申请日 2018年4月9日，公开日 2018年11月6日
3. 彭锦安，李方林，张琦珊，罗玉婷，肖奇才，高理钱，“一种布洛芬杂质A的制备方法”，中国发明专利申请号: 201810751757.2, 申请日 2018年7月10日，公开日2018年11月13日
2. 彭锦安，李方林，张琦珊，肖奇才，冯伟，高理钱。“一种达格列净异构体杂质Ⅰ的制备方法”。中国发明专利申请号: 201810335379.X, 申请日2018年04月16日，公开日2018年07月24日
1. 温龙平，高理钱，孟 丹。（2005）α-促黑激素的环状类似肽及其应用。中国发明专利申请号CN200510083984.5 (导师第一, 本人第二)