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陈鹏 2020级博士     进组时间: 2020.09    离组时间: 2024.07

陈鹏于20146月本科毕业于南昌大学药学院;2017年7月硕士毕业于南方医科大学药学院;2017.07-2020.08在东阳光药物研发有限公司从事有机合成研究员工作。于20209月进入中山大学药学院(深圳)高理钱老师课题组开始研究生期间的学习,为中山大学2020级在读博士研究生

E-mail: chenp268@mail2.sysu.edu.cn



Publications (After joining SYSU) # Equal contribution* Corresponding author


1P. Chen#, J. Sun#, C. Zhu#, G. Tang*, W. Wang, M. Xu, M. Xiang, C.-J. Zhang, Z.-M. Zhang*, L. Gao*, S. Q. Yao*, “Cell-active, reversible and irreversible covalent inhibitors that selectively target the catalytic lysine of BCR-ABL kinase”, Angew. Chem. Int. Ed. (2022), 61(26):e202203878. (IF 15.336中科院1Top期刊

 

2.  P. Chen#L. Lou # B. Sharma, M. Li, C. Xie, F. Yang , Y. Wu*, Q. Xiao *L. Gao*Recent advances on PKM2 modulators including inhibitors and activators in biomedical applications",Current Medicinal Chemistry (2023),  in pressDOI: 10.2174/0929867331666230714144851. 


3.P. Chen#, G. Tang#, *, C. Zhu#, J. Sun, X. Wang, M. Xiang, H. Huang, W. Wang, L. Li, Z. Zhang*, L. Gao*, S.Q. Yao*, “ 2-Ethynylbenzaldehyde (EBA)-based, lysine-targeting irreversible covalent inhibitors for protein kinases and non-kinases”, J. Am Chem. Soc. (2023)145 (7)3844-3849. (IF16.383中科院1Top Journal).


4. J. Sun#, L. Lou#, C-J Zhu#, P. Chen, G. Tang, M. Gu, S. Xia, X. Dong,* Z.-M. Zhang,* L. Gao,* S.Q. Yao,* Q. Xiao*,Chemical Evolution to Improve Bcr-Abl Kinase Inhibitors via Covalent and Pro-/Dual-drug Targeting Strategies, XXXX (2023), submitted.


5. P. Chen#, J. Sun#, L. Wang#, M. Xiang, M. Gu, F. Miao, X. Wang, L. Duan, P. Yuan, Z.-M. Zhang*, X. Lu*, L. Gao*, S.Q. Yao*, “Cell-Active, Arginine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Non-Kinases”, XXXX (2023), submitted.


6. X. Wang, J. Sun, H. Huang, G. Tang, P. Chen, M. Xiang, L. Li, Z.-M. Zhang,* L. Gao,* S.Q. Yao*, “Kinase Inhibition via Small Molecule-Induced Intramolecular Protein Cross-Linking”, XXXX (2024), submitted.