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杨芬 副研究员     进组时间: 2019.03    离组时间: 2022.03

杨芬博士2018年博士毕业于澳门科技大学,2019年3月加入中山大学药学院(深圳)高理钱老师课题组,现为中山大学副研究员。


E-mail: yangfen3@mail.sysu.edu.cn


Publications (After joining SYSU) # Equal contribution, * Corresponding author


10.  F. Yang#, X. Wang#, J. Sun#, S. Zhou, Q. Xiao, F. Yang*, L. Gao*, Selectively suppressing lung cancer cell via induced autophagy effect enabled by mesopore-encaged highly-dispersed active MnOx in nanosilica", XXXX (2021), submitted. 

9.  F. Yang#, L. Lou#B. Sharma#,  P. Chen, M. Li, D. Zhang, C. Xie, Y. Wu, Q. Xiao *, L. Gao*Recent advances on PKM2 modulators in biomedical applications", Journal of Medicinal  Chemistry (2021), submitted.

8.  L. Wang#, J. Li#, Y. Xiong#, Y. Wu#, F. Yang#, Y. Guo, Z. Chen, L. Gao*, W. Deng*, “Ultrashort peptides and hyaluronic acid based injectable composite hydrogels for sustained drug release and chronic diabetic wound healing", ACS Applied Materials & Interfaces  (2021), 13(49), 58329-58339.

7. F. Yang#, D. Zhang#, Q. Zhou#, M. Li, C. Xie, S. Li, X. Wang, W. Wang, Y. Guo, Q. Xiao*, Y. Wang *L. Gao*, “Peptides-modified polystyrene-based polymers as high-performance substrates for the growth and propagation of human embryonic stem cells”, Chinese Chemical Letters (2021), DOI:10.1016/j.cclet.2021.10.028.

6. Q. Xiao*, X. Dong, F. Yang, S. Zhou, M. Xiang, L. Lou, S.Q. Yao*L. Gao*, “Engineered Cell-penetrating Peptides for Mitochondrion-Targeted Drug Delivery in Cancer Therapy”, Chem. Eur. J.  (2021),  27(59), 14721-14729. 

5. P. Yuan*#, F. Yang#, S.S. Liew#, J. Yan,  X. Dong, J. Wang, S. Du, X. Mao, L. Gao, Shao Q. Yao*, “Intracellular Co-delivery of Native Antibody and siRNA for Combination Therapy by Using Biodegradable Silica Nanocapsules”, Biomaterials (2021), in press.

4. Q. Xiao#, W. Du#, X. Dong, S. Du, S.Y. Ong, G. Tang, C. Zhang, F. Yang, L. Li*, L. Gao*, S.Q. Yao*, “Cell-penetrating mitochondria-targeting ligands for universal delivery of small molecules, proteins and nanomaterials”, Chem. Eur. J. (2021), 27(47), 12207-12214.

3. M. Xiang#, Q. Zhou#, Z. Shi, X. Wang, M. Li, Y. Jia, S. Li, F. Yang, W. Wang, T. Chen, X. Xu, B. Sharma, Y. Nie, Q. Xiao*, L. Gao*, “A review of light sources and enhanced targeting for photodynamic therapy”, Current Medicinal Chemistry (2021), 28(31), 6437-6457

2. L. Gao*, #, W. Wang#, X. Wang#, F. Yang, L. Xie, J. Shen, M.A. Brimble, Q. Xiao*, S. Q. Yao*, “Fluorescent probes for bioimaging of potential biomarkers in Parkinson’s disease”, Chem Soc Rev (2021), 50(2), 1219-1250.

1. B. Sharma#, L. Xie#, F. Yang#, W. Wang#, Q. Zhou, M. Xiang, S. Zhou, W. Lv, Y. Jia, L. Pokhrel, J. Shen, Q. Xiao*, L. Gao*, W. Deng*, “Recent advance on PTP1B inhibitors and their biomedical applications”, European Journal of Medicinal Chemistry (2020),  199:112376, doi:10.1016/j.ejmech.2020.112376.


Patents


6. 高理钱, 石子寒,杨芬肖奇才、谢刘幸、贾艳、李少云、张达, “靶向干扰素γ的多肽及其应用中国发明专利申请号:CN202011423132.7, 申请日2020129 

5. 高理钱,谢刘幸,谈思佳,王璇,李孟础,杨芬,贾艳,肖奇才,沈君,靶向PKM2蛋白的抗肿瘤多肽及其引用中国发明专利申请号:CN202011355591.6, 申请日 20201127


4. 高理钱,李少云,张达,石子寒,杨芬,肖奇才,周士哲,吕婉婷,李晗玥,“靶向BRD4蛋白的抗肿瘤多肽及其应用”, 中国发明专利申请号:CN202010996282.0, 申请日2020922


3. 高理钱,贾艳,肖奇才,杨芬,谢程亮, “一种抗敏组合物及其制备方法和应用中国发明专利申请号CN202010926658.0, 申请日 202097


2. 肖奇才,高理钱周全明,石子寒,汪伟,向梦华,谢刘幸,杨芬,罗川朝。一种氟替卡松丙酸酯中间体的制备方法。中国发明专利申请号:CN202010150457.6, 申请日20200306


1. 高理钱谢刘幸,李孟础,王璇,汪伟,肖奇才,杨芬,沈君,邓文斌。 靶向GRB2 SH2结合域的抗肿瘤多肽及其应用”, 中国发明专利申请号:CN201911258905.8, 申请日 20191210