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肖奇才 副研究员     进组时间: 2017.06    离组时间: 2023.07

肖奇才博士2016年博士毕业于香港中文大学,2017年6月加入中山大学药学院(深圳)高理钱老师课题组,现为中山大学副研究员。


E-mail: xiaoqicai@mail.sysu.edu.cn


去向:广西医科大学


Publications (After joining SYSU) (# Equal contribution, * Corresponding author)


19. L. Lou#, S. Zhou#, S. Tan#, M. Xiang, W. Wang, C. Yuan*, L. Gao* and Q. Xiao*, “Amplifying the Efficacy of ALA-based Prodrugs for Photodynamic Therapy Using Nanotechnology”, Frontiers in Pharmacology (2023)14:1137707

18. F. Yang#, X. Wang#, J. Sun#, S. Tan#, S. Zhou, W. Tu, X. Dong, Q. Xiao, F. Yang*, L. Gao*, Mesopore-Encaged Active MnOx in Nano-Silica Selectively Suppressed Lung Cancer Cell via Induced Autophagy Effect”,  Biomaterials Science (2023), 11(6):2056-2064.

17. C. Yuan#, K. Ai#, M. Xiang, C. Xie, M. Zhao, M. Wu, H. Li, Y. Wu, Y. Cao, C. Li, X. Pei, Y. Zhong, H. K.W. Law, L. Gao, Q. Xiao*, X. Yang*, “Novel 1-hydroxy phenothiazinium-based derivative protects against bacterial sepsis by inhibiting AAK1-mediated LPS internalization and caspase-11 signaling”, Cell Death & Disease (2022), 13(8):722. 

16. C. Yu#, S. Wang#, C. Xu#, Y. Ding, G. Zhang, N. Yang, Q. Wu, Q. Xiao, L. Wang, B. Fang, C. Pu, J. Ge, L. Gao, L. Li*, S.Q. Yao*, “Two-photon small-molecule fluorogenic probes for visualizing endogenous nitroreductase activities from tumor tissues of a cancer patient”, Adv Healthc Mater(2022), e2200400. doi: 10.1002/adhm.202200400.

15.  P. Chen#L. Lou # B. Sharma, M. Li, C. Xie, F. Yang , Y. Wu*, Q. Xiao *L. Gao*Recent advances on PKM2 modulators including inhibitors and activators in biomedical applications",Current Medicinal Chemistry (2023),  in pressDOI: 10.2174/0929867331666230714144851. 

14. F. Yang#, D. Zhang#, Q. Zhou#, M. Li, C. Xie, S. Li, X. Wang, W. Wang, Y. Guo, Q. Xiao*, Y. Wang *L. Gao*, “Peptides-modified polystyrene-based polymers as high-performance substrates for the growth and propagation of human embryonic stem cells”,  Chinese Chemical Letters (2021), DOI:10.1016/j.cclet.2021.10.028.

13. L. Gao*, W. Deng*, J. Shen*, Q. Xiao*, “Editorial: Recent Advances in Strategies and Tools for Efficient Drug Discovery and Delivery—Part II”, Current  Medicinal Chemistry (2021), 28(31), 6304-6306.  

12. Q. Xiao*, X. Dong, F. Yang, S. Zhou, M. Xiang, L. Lou, S.Q. Yao*L. Gao*, “Engineered Cell-penetrating Peptides for Mitochondrion Targeted Drug Delivery in Cancer Therapy”, Chem. Eur. J. (2021),  27(59), 14721-14729. 

11. X. Dong, S. Y. Ong, C. Zhang, W. Chen, S. Du, Q. Xiao, L. Gao, S. Q. Yao*, “Broad-Spectrum Polymeric Nanoquencher as An Efficient Fluorescence Sensing Platform for Biomolecular Detection”, ACS Sensors (2021),  6(8), 3102-3111. 

10. Q. Xiao#, W. Du#, X. Dong, S. Du, S.Y. Ong, G. Tang, C. Zhang, F. Yang, L. Li*, L. Gao*, S.Q. Yao*, “Cell-penetrating mitochondria-targeting ligands for universal delivery of small molecules, proteins and nanomaterials”, Chem. Eur. J. (2021), 27(47), 12207-12214.

9. Q. Xiao, B. Mai, Y. Nie, C. Yuan, M. Xiang, Z. Shi, J. Wu, W.A. Leung, C.S. Xu*, S.Q. Yao*, P. Wang*, L. Gao*, “In Vitro and In Vivo Demonstration of Ultra-Efficient and Broad-Spectrum Antibacterial Agents for Photodynamic Antibacterial Chemotherapy”, ACS Applied Materials & Interfaces (2021), 13(10):11588-11596.

8. M. Xiang#, Q. Zhou#, Z. Shi, X. Wang, M. Li, Y. Jia, S. Li, F. Yang, W. Wang, T. Chen, X. Xu, B. Sharma, Y. Nie, Q. Xiao*, L. Gao*, “A review of light sources and enhanced targeting for photodynamic therapy”, Current Medicinal Chemistry (2021), 28(31), 6437-6457.

7. L. Gao*, #, W. Wang#, X. Wang#, F. Yang, L. Xie, J. Shen, M.A. Brimble, Q. Xiao*, S. Q. Yao*, “Fluorescent probes for bioimaging of Parkinson’s disease”, Chem. Soc. Rev. (2021), 50(2), 1219-1250.

6. B. Sharma#, L. Xie#, F. Yang#, W. Wang#, Q. Zhou, M. Xiang, S. Zhou, W. Lv, Y. Jia, L. Pokhrel, J. Shen, Q. Xiao*, L. Gao*, W. Deng*, “Recent advance on PTP1B inhibitors and their biomedical applications”, European Journal of Medicinal Chemistry (2020),  199:112376, doi:10.1016/j.ejmech.2020.112376.

5. Q. Xiao, H. Lin, J. Wu, X. Pang, Q. Zhou, Y. Jiang, P. Wang, A. W. Leung, H. Lee, S. Jiang, S.Q. Yao, L. Gao*, G. Liu*, C.-S. Xu*, “Pyridine Embedded Phenothiazinium Dyes as Lysosome-Targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy”, Journal of Medicinal Chemistry (2020), 63(9), 4896-4907. 

4. J. Ding#, J. Chen#, L. Gao#, Z. Jiang, Y. Zhang, M. Li, Q. Xiao, S.S. Lee*, X. Chen*, “Engineered nanoplatforms for enhanced tumor penetration”, Nano Today (2019), 100800.

3. Q. Xiao#, W. Zhu#, W. Feng#, S. S. Lee, A.W. Leung, J. Shen*, L. Gao*, C. Xu*, “A Review of Resveratrol as a Potent Chemoprotective and Synergistic Agent in Cancer Chemotherapy”, Frontiers in Pharmacology (2019), 9:1534.

2. J. Wang, Z. Zhu, L. Qiu, J. Wang, X. Wang,*, Q. Xiao, J. Xia, L. Liu, X. Liu, W. Feng, J. Wang, P. Miao*, L. Gao*, “A CE-FL based method for real time detection of in-capillary self-assembly of the nanoconjugates of polycysteine ligand and quantum dots”, Nanotechnology (2018), 29(27), 274001.

1. Q. Xiao, J. Wu, X. Pang, Y. Jiang, W. A. Leung, L. Gao, S. Jiang, C. Xu*, “Discovery and Development of Natural Products as Photosensitizers for Photodynamic Therapy”, Current Medicinal Chemistry (2018), 25(7), 839-860.

 

Patents


14. 高理钱,贾艳,李孟础,张达,谢程亮,肖奇才,王璇,孙杰, “一种具有抗氧化作用的活性六肽及其应用”,中国发明专利申请号202210356747.3,申请日202246


13.高理钱,李孟础,张达,谈思佳,周士哲,谢程亮,肖奇才,杨芬,沈君,“靶向DAT蛋白的多肽及其应用”,中国发明专利申请号202210394456.5,申请日2022412


12. 肖奇才高理钱周士哲, "一种靶向线粒体的多肽及其制备方法与应用", 中国专利申请号202110846100.6, 申请日: 20210726公开日: 2021年11月09

11. 高理钱, 石子寒,杨芬,肖奇才、谢刘幸、贾艳、李少云、张达, “靶向干扰素γ的多肽及其应用中国发明专利申请号:CN202011423132.7, 申请日2020129 

10. 高理钱,谢刘幸,谈思佳,王璇,李孟础,杨芬,贾艳,肖奇才,沈君,靶向PKM2蛋白的抗肿瘤多肽及其引用中国发明专利申请号:CN202011355591.6, 申请日 20201127


9. 高理钱,李少云,张达,石子寒,杨芬,肖奇才,周士哲,吕婉婷,李晗玥,“靶向BRD4蛋白的抗肿瘤多肽及其应用”, 中国发明专利申请号:CN202010996282.0, 申请日2020922


8. 高理钱,贾艳,肖奇才,杨芬,谢程亮, “一种抗敏组合物及其制备方法和应用中国发明专利申请号CN202010926658.0, 申请日 202097


7. 肖奇才高理钱周全明,石子寒,汪伟,向梦华,谢刘幸,杨芬,罗川朝。一种氟替卡松丙酸酯中间体的制备方法。中国发明专利申请号:CN202010150457.6, 申请日20200306


6. 肖奇才,尹国建,高理钱,向梦华。一种激光器。中国发明专利申请号:CN202010151860.0, 申请日20200306


5. 肖奇才,尹国建,高理钱,向梦华。一种激光器。中国实用新型专利申请号:CN202020273439.2, 申请日20200306日,

授权公告日:2020109日,专利号ZL202020273439.2, 授权公告号CN211655311U


4. 高理钱谢刘幸,李孟础,王璇,汪伟,肖奇才,杨芬,沈君,邓文斌。 靶向GRB2 SH2结合域的抗肿瘤多肽及其应用”, 中国发明专利申请号:CN201911258905.8, 申请日 20191210


3. 彭锦安,李方林,张琦珊,肖奇才,冯伟,高理钱, “一种米索前列醇酸的制备方法及其用途”, 中国发明专利申请号: 201810308887.9, 申请日 201849日,公开日 2018116


2. 彭锦安,李方林,张琦珊,罗玉婷,肖奇才,高理钱,“一种布洛芬杂质A的制备方法”,中国发明专利申请号: 201810751757.2, 申请日 2018710日,公开日20181113 


1. 彭锦安,李方林,张琦珊,肖奇才,冯伟,高理钱。一种达格列净异构体杂质的制备方法。中国发明专利申请号:201810335379.X, 申请日20180416日,公开日20180724