孙杰于2017年6月本科毕业于临沂大学;2020年6月硕士毕业于哈尔滨医科大学。于2020年9月进入中山大学药学院(深圳)高理钱老师课题组开始研究生期间的学习,为中山大学2020级在读博士研究生。
E-mail: sunj86@mail2.sysu.edu.cn
Publications (After joining SYSU) (# Equal contribution, * Corresponding author)
1. P. Chen#, J. Sun#, C. Zhu#, G. Tang*, W. Wang, M. Xu, M. Xiang, C.-J. Zhang, Z.-M. Zhang*, L. Gao*, S. Q. Yao*, “Cell-active, reversible and irreversible covalent inhibitors that selectively target the catalytic lysine of BCR-ABL kinase”, Angew. Chem. Int. Ed. (2022), 61(26):e202203878.. (IF 15.336, 中科院1区,Top期刊)
2. F. Yang#, X. Wang#, J. Sun#, S. Tan#, S. Zhou, W. Tu, X. Dong, Q. Xiao, F. Yang*, L. Gao*, “Mesopore-Encaged Active MnOx in Nano-Silica Selectively Suppressed Lung Cancer Cell via Induced Autophagy Effect”, Biomaterials Science (2022), 11(6):2056-2064.
3. P. Chen#, G. Tang#, *, C. Zhu#, J. Sun, X. Wang, M. Xiang, H. Huang, W. Wang, L. Li, Z. Zhang*, L. Gao*, S.Q. Yao*, “ 2-Ethynylbenzaldehyde (EBA)-based, lysine-targeting irreversible covalent inhibitors for protein kinases and non-kinases”, J. Am Chem. Soc. (2023), 145 (7),3844-3849. (IF16.383, 中科院1区,Top Journal).
4. J. Sun#, L. Lou#, C-J Zhu#, P. Chen, G. Tang, M. Gu, S. Xia, X. Dong,* Z.-M. Zhang,* L. Gao,* S.Q. Yao,* Q. Xiao*,“Chemical Evolution to Improve Bcr-Abl Kinase Inhibitors via Covalent and Pro-/Dual-drug Targeting Strategies”, XXXX (2023), submitted.
5. P. Chen#, J. Sun#, L. Wang#, M. Xiang, M. Gu, F. Miao, X. Wang, L. Duan, P. Yuan, Z.-M. Zhang*, X. Lu*, L. Gao*, S.Q. Yao*, “Cell-Active, Arginine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Non-Kinases”, XXXX (2023), submitted.
6. X. Wang, J. Sun, H. Huang, G. Tang, P. Chen, M. Xiang, L. Li, Z.-M. Zhang,* L. Gao,* S.Q. Yao*, “Kinase Inhibition via Small Molecule-Induced Intramolecular Protein Cross-Linking”, XXXX (2024), submitted.
Patents
1. 高理钱,贾艳,李孟础,张达,谢程亮,肖奇才,王璇,孙杰, “一种具有抗氧化作用的活性六肽及其应用”,中国发明专利申请号202210356747.3,申请日2022年4月6号