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成果及论文

近五年发表的SCI文章一览

1.        Zhongtao Zhang, Ruyi Wang, Xiaoxian Huang, Renjie Luo, Jingwei Xue, Jing Gao, Wenyuan Liu, Fulei Liu*, Feng Feng*, and Wei Qu*. Self-Delivered and Self-Monitored Chemo-Photodynamic Nanoparticles with Light-Triggered Synergistic Antitumor Therapies by Downregulation of HIF-1α and Depletion of GSH. ACS Applied Materials & Interfaces, 2020, 12(5): 5680-5694(IF8.456).

2.        Minghua Chen, Renzhong Wang, Wuli Zhao, Liyan Yu, Conghui Zhang, Shanshan Chang, Yan Li, Tao Zhang, Jianguo Xing, Maoluo Gan, Feng Feng*, Shuyi Si*. Isocoumarindole A, a Chlorinated Isocoumarin and Indole Alkaloid Hybrid Metabolite from an Endolichenic Fungus Aspergillus sp.. Organic Letters 2019, 21 (5) , 1530-1533(IF6.555).

3.        Fulei Liu, Xiaoxian Huang, Lingfei Han, Mangmang Sang, Lejian Hu, Bowen Liu, Bingjing Duan, Pan Jiang, Xin Wang, Zhou Qiao, Congyu Ma, Wenyuan Liu, Jun Liu,* Feng Feng*, Wei Qu*.  Improved Druggability of Gambogic Acid Using a Core-Shell Nanoparticle. [J] Biomaterials Science2019, 7, 1028–1042. (IF 5.831)

4.        Jian Xu, Hui-Lin Zhu, Jie Zhang, Wen-Yuan Liu, Jian-Guang Luo, Ke Pan, Wen-Yuan Cao, Qi-Rui Bi, Feng Feng,* and Wei Qu*. Littordials A-E, Novel Formyl-Phloroglucinol- β-caryophyllene Meroterpenoids from the Leaves of Psidium littorale. Organic Chemistry Frontiers. 2019, 6, 1667-1673. (IF 5.076)

5.        Jian Xu, Yun-Wei Hu, Wei Qu, Ming-Hua Chen, Liang-Sheng Zhou, Qi-Rui Bi, Jian-Guang Luo, Wen-Yuan Liu, Feng Feng*, and Jie Zhang.* Cytotoxic and neuroprotective activities of constituents from Alternaria alternate, a fungal endophyte of Psidium littorale. Bioorganic Chemistry. 2019, 90: 103046. (IF 3.929)

6.        Eryan Guo, Yunwei Hu, Tao Du, Huilin Zhu, Lei Chen, Wei Qu, Jie Zhang, Ning Xie, Wenyuan Liu, Feng Feng*, Jian Xu*. Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo. Bioorganic Chemistry. 2019, 92:103258. (IF 3.929)

7.        Jia-xin Cheng, Bo-dou Zhang, Wan-fang Zhu, Chao-feng Zhang, Yi-min Qin, Masahiko Abe, Toshihiro Akihisa, Wen-yuan Liu, Feng Feng*, Jie Zhang*. Traditional uses, phytochemistry, and pharmacology of Ficus hispida L.f.: A review. Journal of Ethnopharmacology, 2020, 248, 112204. (IF:3.414)

8.        Jian-Qi Xiao, Wen-Yuan Liu, Hao-peng Sun, Wei Li, Kazuo Koike, Takashi Kikuchi, Takeshi Yamada, Da Li, Feng Feng*, Jie Zhang*. Bioactivity-based analysis and chemical characterization of hypoglycemic and antioxidant components from Artemisia argyi. Bioorganic Chemistry, 2019, 92, 103268. (IF:3.926)

9.        Lingfei Han, Yingming Wang, Xiaoxian Huang, Bowen Liu, Lejian Hu, Congyu Ma, Jun Liu, Jingwei Xue, Wei Qu, Fulei Liu, Feng Feng*, Wenyuan Liu*. A stage-specific cancer chemotherapy strategy through flexible combination of reduction-activated charge-conversional core-shell nanoparticles. Theranostics, 2019, 9(22): 6532- 6549.IF=8.063

10.     Mangmang Sang, Renjie Luo, Yidan Bai, Jun Dou, Zhongtao Zhang, Fulei Liu, Feng Feng*, Jian Xu*, Wenyuan Liu*. Mitochondrial membrane anchored photosensitive nano-device for lipid hydroperoxides burst and inducing ferroptosis to surmount therapy-resistant cancer,Theranostics,2019; 9(21):6209-6223. (IF 8.063)

11.     Mangmang Sang, Renjie Luo, Yidan Bai, Jun Dou, Zhongtao Zhang, fulei Liu, Feng Feng*, wenyuanliu*. BHQ-Cyanine-Based “Off–On” Long-Circulating Assembly as a Ferroptosis Amplifier for Cancer Treatment: A Lipid-Peroxidation Burst Device, ACS Applied Materials & Interfaces, 2019, 11:42873−42884.(IF8.456)

12.     Mangmang Sang, Lingfei Han, Renjie Luo, Wei Qu, Feng Zheng, Kaigang Zhang, Fulei Liu, JingweiXue, Wenyuan Liu* and Feng Feng*. CD44 targeted redox-triggered self-assembly with magnetic enhanced EPR effects for effective amplification of gambogic acid to treat triple-negative breast cancer, Biomaterials Science. 2019,8(1):212-223.(IF 5.251)

13.     Lei Chen, Pan Jiang, Jinsong Li, ZijianXie, Yunhui Xu, Wei Qu, Feng Feng*, Wenyuan Liu*, Periplocin Promotes Wound Healing Through the Activation of Src/ERK and PI3K/Akt Pathways Mediated by Na/K-ATPase, Phytomedicine, 2019, 57:72-83IF 3.610

14.     Jinsong Li, Lei Chen, Jian XuZijianXieYunhui XuPan JiangBingjingDuanXiaoxian HuangFeng Feng*, Wenyuan Liu*, Effects of Periplocaforrestii Schltr on wound healing by Src meditated Mek/Erk and PI3K/Akt signals. Journal of Ethnopharmacology. 2018, IF 2.981

15.     Jiang, Xueyang; Chen, Tingkai; Zhou, Junting.; He, Siyu.; Yang, Hongyu; Chen, Yao; Qu, Wei; Feng, Feng*; Sun, Haopeng*. Dual GSK-3 beta/AChE Inhibitors as a New Strategy for Multitargeting Anti -Alzheimer's Disease Drug Discovery. ACS Medicinal Chemistry Letters 2018, 9(3), 171-176.

16.    Jian Xu, Huilin Zhu, Jie Zhang, Tao Du, Eryan Guo, Wenyuan Liu, Jianguang Luo, Feng Ye, Feng Feng*, Wei Qu*. Sesquiterpenoids from Chloranthus anhuiensis with Neuroprotective Effects in PC12 Cells. [J] Journal of Natural Products. 2018, 81(6): 1391-1398.

17.    Mangmang Sang, Zhongtao Zhang, Fulei Liu, Lejian Hu, Lingchao Li, Li Chen, Feng Feng*, Wenyuan Liu*, Wei Qu*. Multifunctional Hyaluronic Acid-Decorated Redox-Responsive Magnetic Complex Micelle for Targeted Drug Delivery with Enhanced Antitumor Efficiency and Anti-Cell-Migration Activity. [J] Journal of Biomedical Nanotechnology, 2018, 14, 477-495.

18.    Jie Zhang, Wanfang Zhu, Jian Xu, Worapong Kitdamrongtham, Aranya Manosroi, Jiradej Manosroi, Harukuni Tokuda, Masahiko Abe, Toshihiro Akihisa*, Feng Feng**. Potential cancer chemopreventive and anticancer constituents from the fruits of Ficus hispida L.f. (Moraceae). [J] Journal of Ethnopharmacology, 2018, 214, 37-46.

19.    Guiyi Gong, Lingling Jiang, Qinghua Lin, Wenyuan Liu, Ming-Fang He, Jie Zhang, Feng Feng*, Wei Qu*, Ning Xie. In vivo toxic effects of 4-methoxy-5-hydroxy-canthin-6-one in zebrafish embryos via copper dyshomeostasis and oxidative stress. [J] Comparative Biochemistry and Physiology - Part C: Toxicology & Pharmacology, 2018, 204, 79-87.

20.    Jie Zhang, Wanfang Zhu, Weiyuan Zhu, Panpan Yang, Jian Xu, Jiradej Manosroi, Takashi Kikuchi, Masahiko Abe, Toshihiro Akihisa*, Feng Feng*. Melanogenesis-Inhibitory and Cytotoxic Activities of Chemical Constituents from the Leaves of Sauropus androgynus L. MERR. (Euphorbiaceae). [J] Chemistry & Biodiversity, 2018, 15(2).

21.    Xueyang Jiang, Junting Zhou, Qinghua Lin, Guiyi Gong, Haopeng Sun, Wenyuan Liu, Qinglong Guo, Feng Feng, Wei Qu. Anti-angiogenic and anticancer effects of baicalein derivatives based on transgenic zebrafish model[J]. Bioorganic & Medicinal Chemistry, 2018, 26(15): 4481-4492.

22.    Yuanyuan Shi, Ruoqi Wang, Xiaoyu Zhu, Dongge Xu, Liu wenyuan*, Feng Feng*. A self-feedback network based on liquid chromatography-quadrupole- time of flight mass spectrometry for system identification of β-carboline alkaloids in Picrasma quassioides. [J] Scientific report, 2017, 7(1).

23.  Xin Wang, Mei Zheng, Jia Liu, Zhifeng Huang, Yidan Bai, Zhuoying Ren, Ziwen Wang, Yangli Tian, Zhou Qiao, Wenyuan Liu*, Feng Feng*, Differences of first-pass effect in the intestine and liver contribute to stereoselective pharmacokinetics of rhynchophylline and isorhynchophylline epimers in rats. [J] Journal of Ethnopharmacology, 2017, 209, 175-183.

24.    Lei Chen, Jinsong Li, Xuan Ke, Wei Qu, Jie Zhang, Feng Feng*, Wenyuan Liu*. The therapeutic effects of periploca forrestii, schltr. stem extracts on collagen-induced arthritis by inhibiting the activation of src/nf-κb signaling pathway in rats. [J] Journal of Ethnopharmacology, 2017, 202, 12-19.

25.    Lei Chen, MengLin Wei,Jiaojiao Zhao, Hao Hong, Wei Qu, Feng Feng*,Wenyuan Liu*. GTS40, an active fraction of Gou Teng-San (GTS), protects PC12 from H2O2-induced cell injury through antioxidative properties. [J] Chinese Journal of Natural Medicines, 2017, 15(7), 0495-0504.

26.    Jie Zhang, Dan Miao, Wanfang Zhu, Jian Xu, Wenyuan Liu, Worapong Kitdamrongtham, Jiradej Manosroi, Masahiko Abe, Toshihiro Akihisa*, Feng Feng*. Biological Activities of Phenolics from the Fruits of Phyllanthus emblica Linn. (Euphorbiaceae). [J] Chemistry & Biodiversity, 2017, 14(12).

27.    Cailing Sun, Lei Chen, Jian Xu, Wei Qu, Li Guan, Wenyuan Liu, Toshihiro Akihisa, Feng Feng*, Jie Zhang*. Melanogenesis-inhibitory and antioxidant activities of Phenolics from Periploca forrestii. [J] Chemistry & Biodiversity, 2017, 14(8).

28.    Xueyang Jiang , Xinchen Li , Wenyuan Liu , Yunhui Xu , Feng Feng **, Wei Qu*, An efficient, scalable approach to hydrolyze flavonoid glucuronides via activation of glycoside bond. [J] Tetrahedron, 2017, 73(14).

29.    Jian Xu, Di Xiao, Qinghua Lin, Jingfeng He, Wenyuan Liu, Ning Xie, Feng Feng*, Wei Qu*. Cytotoxic Tirucallane and Apotirucallane Triterpenoids from the Stems of Picrasma quassioides. [J] Journal of Natural Products, 2016, 79(8), 1899-1910.

30.  Guiyi Gong, Qinghua Lin, Jian Xu, Feng Ye, Lingling Jiang, Wenyuan Liu, Mingfang He, Feng Feng*, Wei Qu*, Ning Xie. In vivo SAR and STR analyses of alkaloids from Picrasma quassioides identify 1-hydroxymethyl-8-hydroxy-β- carboline as a novel natural angiogenesis inhibitor. [J] RSC Advance, 2016, 6, 9484-9494.

31.  Li Guan, Yanfeng Hao, Lei Chen, Menglin Wei, Qin Jiang, Wenyuan Liu, Yanbo Zhang, Jie Zhang, Feng Feng*,Wei Qu*. Synthesis and evaluation of neuroprotective 4-O-substituted chrysotoxine derivatives as potential multifunctional agents for the treatment of Alzheimer’s disease. [J] RSC Advance, 2016, 6, 22827-22838.

32.    Chen Wang, Hailing Liu, Yuqian Li, Jing Cao, Bo Zheng, Xinghua Xia*, Feng Feng*. A novel device of array nanochannels integrated electrochemical detector for detection of amyloid β aggregation and inhibitor screening. [J] Electrochemistry Communications, 2016, 66, 25-28.

33.    Lei Chen, Lejian Hu, Jiaojiao Zhao, Hao Hong, Feng Feng*, Wei Qu, Wenyuan Liu*. Chotosan improves Aβ1–42-induced cognitive impairment and neuroinflammatory and apoptotic responses through the inhibition of TLR-4/NF-κB signaling in mice. [J] Journal of Ethnopharmacology, 2016, 191, 398-407.

34.    Yuanyuan Shi, Hao Zhan, Liuyi Zhong, Fangrong Yan, Feng Feng*, Wenyuan Liu*, Ning Xie. Total ion chromatographic fingerprints combined with chemometrics and mass defect filter to predict antitumor components of Picrasma quassioids. [J] Journal of Separation Science, 2016, 39, 2633-2641.

35.    Yuanyuan Shi, Yuanyuan Xia, Jueyu Wang, Jinfeng He, Feng Feng*, Wenyuan Liu*. Metabolic profile of 5-hydroxy-4-methoxycanthin-6-one, a typical canthinone alkaloid, in rats determined by liquid chromatography-quadrupole time-of-flight tandem massspectrometry together with multiple data processing techniques. [J] Journal of Pharmaceutical and Biomedical Analysis, 2016, 129, 60-69.

36.    Jian Xu, Di Xiao, Weiwu Song, Lei Chen, Wenyuan Liu, Ning Xie, Feng Feng*, Wei Qu*. Quassinoids from the stems of Picrasma quassioides and their cytotoxic and NO production-inhibitory activities. [J] Fitoterapia, 2016, 110, 13-19.

37.    Jing Tang, Jian Xu, Jie Zhang, Wenyuan Liu, Ning Xie, Lei Chen, Feng Feng*, Wei Qu*. Novel tirucallane triterpenoids from the stem bark of Toona sinensis. [J] Fitoterapia, 2016, 112, 97-103.

38.    Ya Xie, Jie Zhang, Wenyuan Liu, Ning Xie, Feng Feng*, Wei Qu*. New urushiols with platelet aggregation inhibitory activities from resin of Toxicodendron vernicifluum. [J] Fitoterapia, 2016, 112, 38-44.

39.    Menglin Wei, Lei Chen, Jiazhuo Liu, Jiaojiao Zhao, Wenyuan Liu*, Feng Feng*. Protective effects of a Chotosan Fraction and its active components on β-amyloid-induced neurotoxicity.[J] Neuroscience Letters, 2016, 617,143-149.

40.    Qian Zhang, Lei Chen, Lejian Hu, Wenyuan Liu, Feng Feng*, Wei Qu*. Two new ortho benzoquinones from Uncaria rhynchophylla. [J] Chinese Journal of Natural Medicines, 2016, 14(3), 232-235.

41.    Qian Zhang, JiaoJiao Zhao, Jian Xu, Feng Feng*, Wei Qu*, Medicinal uses, phytochemistry and pharmacology of the genus Uncaria. [J] Journal of Ethnopharmacology, 2015, 171, 247-263.

42.    Xinwei Lou, Qinghua Lin, Guanyu Zhang, Wenyuan Liu, Feng Feng*, Wei Qu *. Identification and characterization of three new flavonoids from Rhododendron dauricum. [J] Chinese Journal of Natural Medicines, 2015, 13(8), 628-633.

43.    Yuanyuan Shi, Chunyan Hong, Jian Xu, Xiaoling Yang, Ning Xie, Feng Feng*, Wenyuan Liu*. Simultaneous quantification of two canthinone alkaloids of Picrasma quassioides in rat plasma by liquid chromatography–tandem mass spectrometry and its application to a rat pharmacokinetic study. [J] Journal of Chromatography B, 2015, 986-987, 100-107.

44.    Lijuan Wang, Xiaoyu Zhu, Xinwei Lou, Feng Zheng, Yichen Feng, Wenyuan Liu*, Feng Feng*, Ning Xie. Systematic characterization and simultaneous quantification of the multiple components of Rhododendron dauricum based on high- performance liquid chromatography with quadrupole time-of-flight tandem mass spectrometry. [J] Journal of Separation Science, 2015, 38 (18), 3161-3169 

45.    Yurong Zhao, Wei Qu, Wenyuan Liu, Hao Hong*, Feng Feng*, Han Chen,  Ning Xie. YGS40, an active fraction of Yi-Gan San, reduces hydrogen peroxide-induced apoptosis in PC12 cells. [J] Chinese Journal of Natural Medicines, 2015, 13(6), 438-444.

46.    Yanan Gai, Han Chen, Wenyuan Liu*, Feng Feng*, Ning Xie. The metabolism of YiGan San and subsequent pharmacokinetic evaluation of four metabolites in rat based on liquid chromatography with tandem mass spectrometry. [J] Journal of Chromatography B, 2014, 972, 22-28.

47.    Rui Deng, Yunhui Xu, Feng Feng*, Wenyuan Liu*. Identification of poliumoside metabolites in rat feces by high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. [J] Journal of Chromatography B, 2014, 969, 285-296.

48.    Jiajia Liu, Haimei Wu, Feng Zheng, Wenyuan Liu*, Feng Feng*, Ning Xie. Chemical constituents of Meconopsis horridula and the simultaneous quantification by high-performance liquid chromatography coupled with tandem mass spectrometry. [J] Journal of Separation Science, 2014, 37, 2513-2522.

49.    Han Chen, Yuanyuan Shi, Menglin Wei, Wenyuan Liu*, Feng Feng*. Chemical profile of the active fraction of Yi-Gan San by HPLC–DAD–Q-TOF–MS and its neuroprotective effect against glutamate-induced cytotoxicity. [J] Chinese Journal of Natural Medicines, 2014, 1212(11), 869-880.

50.    Feng Feng, Xiyu Xu , Fulei Liu, Wenyuan Liu*, Ning Xie. Triterpenoid saponins from Patrinia scabra. [J] Chinese Journal of Natural Medicines, 2014, 12(1), 43-46.

51.    Debiao Yan, Dongping Zhang, Ming Li, Wenyuan Liu*, Feng Feng*, Bin Di,  Qinglong Guo, Ning Xie. Synthesis and cytotoxic activity of 3,4,11- trihydroxyl modified derivatives of bergenin. [J] Chinese Journal of Natural Medicines, 2014, 12(12), 929-936.

52.    Yanan Gai, Han Chen, Chunyong Wu, Feng Feng*, Yixiang Wang, WenYuan Liu*, Suilou Wang. Analysis of the traditional medicine YiGan San by the ragmentation patterns of cadambine indole alkaloids using HPLC coupled with high-resolution MS. [J] Journal of separation science, 2013, 36, 3723-3732.

53.    Lin Li, Yanyang Zhao, Wenyuan Liu*, Feng Feng*, Ning Xie. HPLC with quadrupole TOF-MS and chemometrics analysis for the characterization of Folium Turpiniae from different regions. [J] Journal of separation science, 2013, 36, 2552-2561.

54.    Shuanglu Xie, Yuanyuan Shi, Yixiang Wang, Chunyong Wu, Wenyuan Liu*, Feng Feng*, Ning Xie. Systematic identification and quantification of tetracyclic monoterpenoid oxindole alkaloids in Uncaria rhynchophylla and their fragmentations in Q-TOF-MS spectra. [J] Journal of Pharmaceutical and Biomedical Analysis, 2013, 81-82, 56-64.

55.    Yatao Shi, Chunyong Wu, Yanhua Chen, Wenyuan Liu*, Feng Feng*, Ning Xie. Comparative analysis of three Callicarpa herbs using high performance liquid chromatography with diode array detector and electrospray ionization-trap mass spectrometry method. [J] Journal of Pharmaceutical and Biomedical Analysis. 2013, 75, 239-247.

56.    Ying Xia, Chunyong Wu, Wenyuan Liu*, Feng Feng*, Zhiyu Li. Anovel process related impurity and forced degradation study of synthetic wogonin: Development of a liquid chromatographic method for purity control. [J] Journal of Pharmaceutical and Biomedical Analysis, 2012, 71, 168-172.