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成果及论文

代表性论文列表

1)  Yuhang Dong, Jingping Wang, Ling Chen, Haonan Chen, Shuangbo Dang, Feng Li*. Aptamer-based assembly systems for SARS-CoV-2 detection and therapeutics. Chemical Society Reviews, 2024, 53, 6830-6859.

2)Yuhang Dong+, Ling Chen+, Junwei Hou, Yun Sun, Zibo Han, Jing Zhang, Yu Liang, Yongjun Feng, Jin Ren, Qiming Li*, Guangjun Nie*, Feng Li*. DNA programmed Mg-Al layered double hydroxide-based bi-adjuvant nanovaccines. Nano Today, 2024, 57, 102352.

3) Yunhua Guo, Wenzhe Song, Yuhang Dong, Xuejun Wang*, Guangjun Nie, and Feng Li*. A Poly Aptamer Encoded DNA Nanocatcher Informs Efficient Virus Trapping. Nano Letters, 2024, 12, 3614-3623. 

4) Yuhang Dong+, Yunhua Guo+, Wenzhe Song+, Guangjun Nie*, Feng Li*. Functional Integration of DNA and Peptide-Based Supramolecular Nanoassemblies for Cancer Therapy. Accounts of Materials Research, 2023, 4, 10, 892-905.

5)Jing Li+, Jingping Wang+, Ling Chen+, Yuhang Dong+, Haonan Chen+, Guangjun Nie, Feng Li*. Self-Assembly of DNA Molecules at Bio-Interfaces and Their Emerging Applications for Biomedicines. Nano Research, 2023, 16, 13014-13028. doi:    10.1007/s12274-023-5597-y     . 

6)    Feng Li, Xiaolei Sun, Jing Yang, Jin Ren, Mengxue Huang, Shengqi Wang*, Dayong Yang*. A Thermal and Enzymatic Dual-Stimuli Responsive DNA-Based Nanomachine for Controlled mRNA Delivery. Advanced Science, 2023, 10, 2204905.       

7)    Nachuan Song+, Shuai Li+, Zhaoyue Lv+, Xiaohui Ding, Feng Li*  Dayong Yang*. Engineering CRISPR/Cas-based nanosystems for therapeutics, diagnosis and bioimaging. Chinese Chemical Letters, 2023, 108134, doi:   10.1016/j.cclet.2023.108134.

8)    Yuhang Dong+, Feng Li+, Zhaoyue Lv, Shuai Li, Meihe Yuan, Nachuan Song, Jinqiao Liu, Dayong Yang*. Lysosome Interference Enabled by Proton-Driven Dynamic Assembly of DNA Nanoframework inside Cells. Angewandte Chemie International Edition, 2022, 61, e202207770.          

9)     Feng Li+, Yujie Liu+, Yuhang Dong, Yiwen Chu, Nachuan Song, Dayong Yang*. Dynamic Assembly of DNA Nanostructures in Living Cells for Mitochondrial Interference. Journal of the American Chemical Society, 2022, 144, 4667-4677.       

10)      Feng Li+, Nachuan Song+, Yuhang Dong, Shuai Li, Linghui Li, Yujie Liu, Zhemian Li, Dayong Yang*. A Proton-Activatable DNA-Based Nanosystem Enables Co-Delivery of CRISPR/Cas9 and DNAzyme for Combined Gene TherapyAngewandte Chemie International Edition, 2022, 61, e202116569.       

11)      Huaixin Zhao+, Linghui Li+, Feng Li*, Chunxia Liu, Mengxue Huang, Jiao Li, Feng Gao, Xinhua Ruan, Dayong Yang*. An Energy-Storing DNA-Based Nanocomplex for Laser-Free Photodynamic TherapyAdvanced Materials, 2022, 34, 2109920.       

12)    Feng Li+, Wenting Yu+, Jiaojiao Zhang, Yuhang Dong, Xiaohui Ding, Xinhua Ruan, Zi Gu, Dayong Yang*. Spatiotemporally Programmable Cascade Hybridization of Hairpin DNA in Polymeric Nanoframework for Precise siRNA DeliveryNature Communications, 2021, 12, 1138.

13)      Feng Li+, Zhaoyue Lv+, Xue Zhang, Yuhang Dong, Xiaohui Ding, Zhemian Li, Shuai Li, Chi Yao, Dayong Yang*. Supramolecular Self-Assembled DNA Nanosystem for Synergistic Chemical and Gene Regulations on Cancer Cells. Angewandte Chemie International Edition, 2021, 133, 25761.       

14)     Huaixin Zhao+, Zhili Zhang+, Duo Zuo+, Linghui Li, Feng Li*, Dayong Yang*. A Synergistic DNA-polydopamine-MnO2 Nanocomplex for Near-Infrared-Light-Powered DNAzyme-Mediated Gene TherapyNano Letters, 2021, 21, 5477.       

15)     Feng Li+, Shuai Li+, Xiaocui Guo, Yuhang Dong, Chi Yao, Yangping Liu, Yuguang Song, Xiaoli Tan, Lizeng Gao, Dayong Yang*. Chiral Carbon Dots Mimicking Topoisomerase I to Enantioselectively Mediate Topological Rearrangement of Supercoiled DNA Enantioselectively       Angewandte Chemie International Edition, 2020, 59, 11087.       

16)     Xiaocui Guo+, Feng Li*, Chunxia Liu, Yi Zhu, Nannan Xiao, Zi Gu, Dan Luo, Jianhui Jiang, Dayong Yang*. Construction of Organelle-Like Architecture via Dynamic DNA Assembly in Living Cells. Angewandte Chemie International Edition, 2020, 59, 20651-20658.       

17)    Xiaocui Guo+, Feng Li+, Lihui Bai, Wenting Yu, Xue Zhang, Yi Zhu, Dayong Yang*. Gene Circuit Compartment on Nanointerface Facilitatating Cascade Gene ExpressionJournal of the American Chemical Society, 2019, 141, 19171.            

18)    Feng Li+, Jianpu Tang+, Jinhui Geng, Dan Luo, Dayong Yang*. Polymeric DNA Hydrogel: Design, Synthesis and ApplicationsProgress in Polymer Science, 2019, 98, 101163.       

19)    Feng Li+, Yiye Li+, Xiao Yang, Xuexiang Han, Yang Jiao, Taotao Wei, Dayong Yang, Huaping Xu*, Guangjur Nie*. Highly Fluorescent Chiral N-S-Doped Carbon Dots from Cysteine Affecting Cellular Energy Metabolism. Angewandte Chemie International Edition, 2018, 57, 2377-2382.     

20)    Feng Li, Tianyu Li, Chenxing Sun, Jiahao Xia, Yang Jiao, Huaping Xu*. Selenium-Doped Carbon Quantum Dots (Se-CQDs) for Free Radical Scavenging. Angewandte Chemie International Edition, 2017, 56, 9910-9914.       


其他论文列表

21)   Shuai Li, Feng Li*, Yuhang Dong, Nachuan Song, Li Pan, Dayong Yang*. Synthesis and Catalytic Property of Ribonucleoside-Derived Carbon Dots. Small, 2022, 18, e2106269.       

22)  Xiaohui Ding, Zhaoyue Lv, Nuo Xu, Feng Li*, Dayong Yang*. Dynamic Transformation of DNA Nanostructures inside Living CellsChenPlusChem2022, 87, e202100519.

23)   Xiaolei Sun, Yuhang Dong, Yujie Liu, Nachuan Song, Feng Li*, Dayong Yang*. Self-Assembly of Artificial Architectures in Living Cells: Design and Applications. Science China Chemistry, 2022, 65, 31-47.      .       

24)   Jinpeng Han, Xiaocui Guo, Feng Li*, Dayong Yang*. Microfluidic Construction of Nucleus-Like Architecture. Chemical Engineering Journal, 2022, 431, 133997.      

25)  Jinpeng Han, Yuchen Cui, Feng Li, Zi Gu, Dayong Yang*. Responsive Disassembly of Nucleic Acid Nanocomplex in Cells for Precision MedicineNano Today, 2021, 39, 101160.

26)   Huaixin Zhao+, Jigang Lv+, Feng Li, Zhili Zhang, Chunzhi Zhang, Zi Gu, Dayong Yang*. Enzymatical Biomineralization of DNA Nanoflowers Mediated by Manganese Ions for Tumor Site Activated Magnetic Resonance ImagingBiomaterials, 2021, 268, 120591.       

27)  Zhaoyue Lv, Yi Zhu, Feng Li*DNA Functional Nanomaterials for Controlled Delivery of Nucleic Acid-based Drugs. Frontiers in Bioengineering and Biotechnology, 2021, 9, 720291.

28)   Huaixin Zhao+, Chunxia Liu+, Zi Gu, Luxi Dong, Feng Li, Chi Yao, Dayong Yang*. Persistent Luminescent Nanoparticles Containing Hydrogel for Targeted, Sustained and Autofluorescence-Free Tumor Metastasis Imaging   Nano Letters, 2020, 20, 252.

29)    Chi Yao+, Weijian Wu+, Han Tang, Xuemei Jia, Jianpu Tang, Xinhua Ruan, Feng Li, David Tai Leong, Dan Luo, Dayong Yang*. Self-assembly of Stem Cell Membrane-Camouflaged Nanocomplex for MicroRNA-Mediated Repair of Myocardial Infarction InjuryBiomaterials, 2020, 257, 120256.       

30)   Huaixin Zhao+, Huiting Zhao+, Yi Jiao, Yi Zhu, Chunxia Liu, Feng Li, Yinsong Wang, Zi Gu, Dayong Yang*. Biosynthetic Molecular Imaging Probe for Tumor-targeted Dual-modal Fluorescence/Magnetic Resonance ImagingBiomaterials, 2020, 256, 120220.   

31)   Feng Li+, Xue Zhang+, Shuxian Hu+, Zhaoyue Lv, Jigang Lv, Wenting Yu, Xihan Xu, Dayong Yang*. Bioinspired Mechanically Responsive Hydrogel upon Redox Mediated by Dynamic Coordination between Tellurometer and Platinum Ions. Chemistry of Materials, 2020, 32, 2156-2165.

32)    Feng Li+, Wenting Yu+, Xue Zhang, Xiaocui Guo, Xihan Xu, Xiaolei Sun, Dayong Yang*. Preparation of Biomimetic Gene Hydrogel via Polymerase Chain Reaction for Cell-Free Protein Expression. Science China Chemistry, 2020, 63, 99-106.       

33)   Yi Zhu+, Xiaocui Guo+, Jinqiao Liu, Feng Li, Dayong Yang*. Emerging Advances of Cell-Free Systems toward Artificial Cells. Small Method,    2020, 4, 2000406.    

34)   Yuhang Dong+, Xiaorui Pan+, Feng Li*, Dayong Yang*. pH-Responsive Reversible DNA Self-Assembly Mediated by Zwitterion. Chemical Research in Chinese Universities, 2020, 36, 285-295.       

35)   Xiaocui Guo+, Lihui Bai+, Feng Li+, Wilhelm T. S. Huck, Dayong Yang*. Branched DNA Architectures Produced by PCR-Based Assembly as Gene Compartments for Cell-Free Gene-Expression Reactions. ChemBioChem, 2019, 20, 2597-260.             

36)   Jiaojiao Zhang+, Feng Li+, Dayong Yang*. DNA: From Carrier of Genetic Information to Polymeric Materials. Transactions of Tianjin University    2019, 25, 301-311.       

37)     Feng Li+, Tianyu Li+, Xuexiang Han, Hao Zhuang, Guangjun Nie, and Huaping Xu*. Nanomedicine Assembled by Coordinated Selenium-Platinum Complexes Can Selectively Induce Cytotoxicity in Cancer Cells by Targeting the Glutathione Antioxidant Defense System. ACS Biomaterial-Science. Engineering, 2019, 6, 1954-1962.    

38)     Feng Li+, Yuhang Dong+, Zhikun Zhang+, Man Lv+, Zhi Wang, Xinhua Ruan, Dayong Yang*. A Recyclable Biointerface Based on Cross-linked Branched DNA Nanostructures for Ultrasensitive Nucleic Acid Detection. Biosensors & Bioelectronics, 2018, 117, 562-566.

39)      Feng Li*, Dayong Yang, Huaping Xu*. Non-Metal Heteroatom Doped Carbon Dots: Synthesis and Property. Chemistry-A European Journal, 2018, 24, 1-       3.       

40)   Feng Li, Tianyu Li, Xuexiang Han, Hao Zhuang, Guangjun Nie, and Huaping Xu*. Nanomedicine Assembled by Coordinated Selenium–Platinum Complexes Can Selectively Induce Cytotoxicity in Cancer Cells by Targeting the Glutathione Antioxidant Defense System.   ACS Biomaterials Science & Engineering, 2018, 4, 1954-1962.

41)   Qianmin Ma+, Feng Li+, Jianpu Tang, Ke Meng, Xihan Xu, Dayong Yang*. Luminescent Ultralong Microfibers Prepared through Supramolecular Self-Assembly of Lanthanide Ions and Thymidine in Water.  Chemistry-A European Journal, 2018, 24, 18890-18896.   

42)    Lu Yang+, Chi Yao+, Feng Li, Yuhang Dong, Zhikun Zhang, Dayong Yang*. Synthesis of Branched DNA Scaffolded Super-Nanoclusters with Enhanced Antibacterial Performance. Small, 2018, 14, 1800185.        

43)   Tianyu Li, Wentian Xiang, Feng Li, Huaping Xu*. Self-Assembly Regulated Anticancer Activity of Platinum Coordinated Selenomethionine. Biomaterials, 2018, 157, 17-25.

44)  Chenxing Sun+, Shaobi Ji+, Feng Li*, Huaping Xu*. Diselenide-Containing Hyperbranched Polymer with Light-Induced Cytotoxicity. ACS Applied Materials & interfaces, 2017, 9, 12924-12929       .       

45)   Jiahao Xia+, Feng Li+, Shaobo Ji, Huaping Xu*. Selenium-Functionalized Graphene Oxide That Can Modulate the Balance of Reactive Oxygen Species. ACS Applied Materials & Interfaces, 2017, 9, 21413-21421.   .       

46)    Weiqiang Zhou, Lu Wang, Feng Li, Weina Zhang, Wei Huang*, Fengwei Huo*, Huaping Xu*. Selenium-Containing Polymer@Metal-Organic Frameworks Nanocomposites as an Efficient Multiresponsive Drug Delivery System. Advanced Functional Materials, 2017, 27, 1605465.      

47)    Suping Li+, Yinlong Zhang+, Jing Wang+, Ying Zhao+, Tianjiao Ji, Xiao Zhao, Yanping Ding, Xiaozheng Zhao, Ruifang Zhao,  Feng Li, Xiao Yang, Shaoli Liu, Zhaofei Liu, Jianhao Lai, Andrew K. Whittaker, Gregory J. Anderson, Jingyan Wei, and Guangjun Nie*. Nanoparticle-mediated Local Depletion of Tumour-associated Platelets Disrupts Vascular Barriers and Augments Drug Accumulation in Tumours. Nature Biomedical. Engineering, 2017, 8, 662-679.   

48)    Tianyu Li+, Feng Li+, Wentian Xiang+, Yu Yi+, Yuyan Chen, Liang Cheng, Zhuang Liu*, and Huaping Xu*. Selenium-Containing Amphiphiles Reduced and Stabilized Gold Nanoparticles: Kill Cancer Cells via Reactive Oxygen Species. ACS Applied Materials & Interfaces, 2016, 8, 22106-22112.       

49)    Fuqiang Fan+, Lu Wang, Feng Li, Yu Fu*, Huaping Xu*. Stimuli-Responsive Layer-by-Layer Tellurium-Containing Polymer Films for the Combination of Chemotherapy and Photodynamic Therapy. ACS Applied Materials & Interfaces, 2016, 8, 17004-17010.3-94037.    

50)   Wei Cao+,  Feng Li+, Ruofan Chena, Huaping Xu*. Tellurium-Containing Nanoparticles for Controlled Delivery of Cisplatin Based on Coordination Interaction. RSC Advances, 2016, 6, 9403-94037.

51)   Feng Li, Jing Wang, Shuqing Sun*, Hai Wang, Zhiyong Tang, Guangjun Nie*. Facile Synthesis of pH-Sensitive Germanium Nanocrystals with High Quantum Yied for Intracellular Acidic Compartment Imaging. Small, 2015, 16, 1954-1961.       

52)    Xiao Zhao, Feng LiYiye Li, Hai Wang, He Ren, Jing Chen, Guangjun Nie*, Jihui Hao*. Co-Delivery of HIF1α siRNA and Gemcitabine via Biocompatible Lipid-Polymer Hybrid Nanoparticles for Effective Treatment of Pancreatic Cancer. Biomaterials, 2015, 46, 13-25. 

53)    Feng Li*, Xiao Zhao+, Hai Wang+, Ruifang Zhao, Tianjiao Ji, He Ren, Gregory J. Anderson, Guangjun Nie*, Jihui Hao*. Multiple Layer-by-Layer Lipid-Polymer Hybrid Nanoparticles for Improved FOLFIRINOX Chemotherapy in Pancreatic Tumor ModelsAdvanced Functional Materials, 2015, 25,    788-798. 

54)    Hai Wang+, Ruifang Zhao+, Yiye Li*, Huiyu Liu, Feng Li+,Yuliang Zhao, Guangjun Nie*Aspect Ratios of Gold Nanoshell Capsules Mediated Melanoma Ablation by Synergistic Photothermal Therapy and Chemotherapy. Nanomedicine, 2015, 12, 439-448. 

55)    Feng Li+, Jing Wang, Yuming Lai, Chong Wu, Shuqing Sun*, Yonghong He, Hui Ma. Ultrasensitive and Selective Detection of Copper (II) and Mercury (II) Ions by Dye-Coded Silver Nanoparticle-based SERS ProbesBiosensors & Bioelectronics, 2013, 39, 82-87.

56)  Yuming Lai, Feng Li, Shuqing Sun*. Controlled Surface Enhanced Resonance Raman Scattering (SERRS) in Biological Environment. Integrated Ferroelectrics, 2013, 146, 88-98.