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成果及论文

Highlights

1. Jinfeng Sun, Xu Huang, Run Shi, Tianjiao Ji, Jianxun Ding*, Xuesi Chen, Enzyme-triggered orthotopic network formation from poly(amino acid) nanoparticle to suppress tumor growth and metastases. Nano Today 2024, 56, 102222. https://doi.org/10.1016/j.nantod.2024.102222


2. Yuanzhen Su#, Weiguo Xu#, Qi Wei, Yang Ma, Jianxun Ding*, Xuesi Chen, Chiral polypeptide nanoparticles as nanoadjuvants of nanovaccines for efficient cancer prevention and therapy. Science Bulletin 2023, 68 (3), 284−294. https://doi.org/10.1016/j.scib.2023.01.024


3. Yang Liu#, Zhongyu Jiang#, Shizheng Tong, Yifu Sun, Yu Zhang, Jiayuan Zhang, Duoyi Zhao, Yuanzhen Su, Jianxun Ding*, Xuesi Chen*, Acidity-Triggered Transformable Polypeptide Self-Assembly to Initiate Tumor-Specific Biomineralization. Advanced Materials 2023, 35 (15), 2203291. https://doi.org/10.1002/adma.202203291 (Back Cover) https://doi.org/10.1002/adma.202370110


4. Luhe Li, Dan Li, Yuanzhen Wang, Tingting Ye, Er He, Yiding Jiao, Lie Wang, Fangyan Li, Yiran Li, Jianxun Ding*, Kai Liu, Junye Ren, Qianming Li, Jianjian Ji, Ye Zhang*, Implantable Zinc-Oxygen Battery for in situ Electrical Stimulation-Promoted Neural Regeneration. Advanced Materials 2023, 35 (32), 2302997. https://doi.org/10.1002/adma.202302997


5. Jin Zhang#, Dongmei Tong#, Honghai Song#, Renjie Ruan, Yifu Sun, Yandai Lin, Jun Wang, Linxi Hou, Jiayong Dai*, Jianxun Ding*, Huanghao Yang*, Osteoimmunity-Regulating Biomimetically Hierarchical Scaffold for Augmented Bone Regeneration. Advanced Materials 2022, 34 (36), 2202044. https://doi.org/10.1002/adma.202202044 (Inside Back Cover) https://doi.org/10.1002/adma.202270257 (ESI Hot Paper)


6. Jiazhen Yang#, Tianqi Su#, Haoyang Zou#, Guanqing Yang, Jianxun Ding*, Xuesi Chen*, Spatiotemporally Targeted Polypeptide Nanoantidotes Improve Chemotherapy Tolerance of Cisplatin. Angewandte Chemie International Edition 2022, 61 (47), e202211136. https://doi.org/10.1002/anie.202211136


7. Zhongyu Jiang#, Yang Liu#, Run Shi#, Xiangru Feng, Weiguo Xu, Xiuli Zhuang, Jianxun Ding*, Xuesi Chen, Versatile Polymer-Initiating Biomineralization for Tumor Blockade Therapy. Advanced Materials 2022, 34 (19), 2110094. https://doi.org/10.1002/adma.202110094 (Inside Back Cover) https://doi.org/10.1002/adma.202270146 (ESI Highly Cited Paper)


8. Pan Zheng, Binbin Ding, Zhongyu Jiang, Weiguo Xu, Gao Li, Jianxun Ding*, Xuesi Chen*, Ultrasound-Augmented Mitochondrial Calcium Ion Overload by Calcium Nanomodulator to Induce Immunogenic Cell Death. Nano Letters 2021, 21 (5), 2088−2093. https://doi.org/10.1021/acs.nanolett.0c04778 (ESI Highly Cited Paper)


9. Jinjin Chen, Jianxun Ding*, Yucai Wang, Jianjun Cheng*, Shengxiang Ji, Xiuli Zhuang, Xuesi Chen*, Sequentially Responsive Shell-Stacked Nanoparticles for Deep Penetration into Solid Tumors. Advanced Materials 2017, 29 (32), 1701170. https://doi.org/10.1002/adma.201701170 (ESI Highly Cited Paper)

代表论文

2024

129.  Hongyan Wei#, Ke Yi#, Fenfang Li, Di Li, Jiazhen Yang, Run Shi, Yuanyuan Jin, Haixia Wang, Jianxun Ding*, Yu Tao*, Mingqiang Li*, Multimodal Tetrahedral DNA Nanoplatform for Surprisingly Rapid and Significant Treatment of Acute Liver Failure. Advanced Materials 2024, In Press. https://doi.org/10.1002/adma.202305826

128.  Chaoyang Li, Yifu Sun, Weiguo Xu, Fei Chang*, Yinan Wang*, Jianxun Ding*, Mesenchymal Stem Cells-Involved Strategies for Rheumatoid Arthritis Therapy. Advanced Science 2024, In Press. https://doi.org/10.1002/advs.202305116

127.  Lingpu Zhang, Jiazhen Yang, Jia Huang, Yingjie Yu, Jianxun Ding*, Johannes Karges*, Haihua Xiao*, Development of tumor-evolution-targeted anticancer therapeutic nanomedicineEVT. Chem 2024, 10 (5), 1337−1356. https://doi.org/10.1016/j.chempr.2023.12.019

126.  Ke Yi#, Huimin Kong#, Yeh-Hsing Lao#, Di Li, Rachel L. Mintz, Tianxu Fang, Guojun Chen, Yu Tao*, Mingqiang Li*, Jianxun Ding*, Engineered Nanomaterials to Potentiate CRISPR/Cas9 Gene Editing for Cancer Therapy. Advanced Materials 2024, 36 (13), 2300665. https://doi.org/10.1002/adma.202300665 (Inside Back Cover) https://doi.org/10.1002/adma.202470097

125.  Juan Wang, Ning Zhang, Xiuping Ding, Chengrui Fu, Xiaodong Li*, Baosheng Li*, Jianxun Ding*, Tianmeng Sun*, Targeted nanostrategies eliminate pre-metastatic niche of cancer. Nano Research 2024, 17 (6), 5358−5373. https://doi.org/10.1007/s12274-024-6412-0

124.  Jinfeng Sun, Xu Huang, Run Shi, Tianjiao Ji, Jianxun Ding*, Xuesi Chen, Enzyme-triggered orthotopic network formation from poly(amino acid) nanoparticle to suppress tumor growth and metastases. Nano Today 2024, 56, 102222. https://doi.org/10.1016/j.nantod.2024.102222

123.  Ganghao Liang, Wanqing Cao, Dongsheng Tang, Hanchen Zhang, Yingjie Yu, Jianxun Ding*, Johannes Karges*, Haihua Xiao*, Nanomedomics. ACS Nano 2024, 18 (17), 10979−11024. https://doi.org/10.1021/acsnano.3c11154

122.  Wanqing Cao, Ye Zhang, Luhe Li, Bin Liu, Jianxun Ding*, Xuesi Chen, Physical cues of scaffolds promote peripheral nerve regeneration. Applied Physics Reviews 2024, 11 (2), 021313. https://doi.org/10.1063/5.0189181


2023
121.  Mengnan Zhao#, Rujing Wang#, Kunmeng Yang#, Yuhong Jiang*, Yachen Peng, Yuke Li, Zhen Zhang, Jianxun Ding*, Sanjun Shi*, Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis. Acta Pharmaceutica Sinica B 2023, 13 (3), 916−941. https://doi.org/10.1016/j.apsb.2022.10.019 (ESI Hot Paper)

120.  Xukai Wang, Mingran Zhang, Tongtong Zhu, Qiuhua Wei*, Guangyao Liu*, Jianxun Ding, Flourishing Antibacterial Strategies for Osteomyelitis Therapy. Advanced Science 2023, 10 (11), 2206154. https://doi.org/10.1002/advs.202206154 (ESI Highly Cited Paper)

119.  Qihui Wang, Jiayi Luan, Zhilong Zhao, Weihui Kong, Congxiao Zhang*, Jianxun Ding*, Dentin-desensitizing biomaterials. Chinese Chemical Letters 2023, 34 (8), 108060. https://doi.org/10.1016/j.cclet.2022.108060

118.  Shixian Liu, Zhonghan Wang, Qi Wei, Xuefeng Duan, Yang Liu, Minfei Wu*, Jianxun Ding*, Biomaterials-enhanced bioactive agents to efficiently block spinal metastases of cancers. Journal of Controlled Release 2023, 363, 721−732. https://doi.org/10.1016/j.jconrel.2023.09.039

117.  Jiayi Luan, Ruotao Li, Weiguo Xu, Huiying Sun, Qiqi Li, Di Wang, Shujun Dong*, Jianxun Ding*, Functional biomaterials for comprehensive periodontitis therapy. Acta Pharmaceutica Sinica B 2023, 13 (6), 2310−2333. https://doi.org/10.1016/j.apsb.2022.10.026

116.  Qiang Luo#, Wei Sun#, Zhibo Li#, Jinfeng Sun, Yu Xiao, Jichang Zhang, Cuilin Zhu, Bin Liu*, Jianxun Ding*, Biomaterials-mediated targeted therapeutics of myocardial ischemia-reperfusion injury. Biomaterials 2023, 303, 122368. https://doi.org/10.1016/j.biomaterials.2023.122368

115.  Luhe Li, Yuanzhen Wang, Tingting Ye, Er He, Yiding Jiao, Lie Wang, Fangyan Li, Yiran Li, Jianxun Ding*, Kai Liu, Junye Ren, Qianming Li, Jianjian Ji, Ye Zhang*, Implantable Zinc-Oxygen Battery for in situ Electrical Stimulation-Promoted Neural Regeneration. Advanced Materials 2023, 35 (32), 2302997. https://doi.org/10.1002/adma.202302997

114.  Yachen Peng#, Yaling Zhuang#, Hanxiang Le, Di Li, Mingran Zhang, Kai Liu, Yanbo Zhang*, Jianlin Zuo*, Jianxun Ding*, Bioinspired Gradient Scaffolds for Osteochondral Tissue Engineering.  Exploration 2023, 3 (4), 20210043. https://doi.org/10.1002/EXP.20210043

113.  Weiguo Xu#, Yuanzhen Su#, Yang Ma, Qi Wei, Jiazhen Yang, Xiuli Zhuang, Jianxun Ding*, Xuesi Chen, Immunologically Effective Poly(D-lactic acid) Nanoparticle Enhances Anticancer Immune Response. Science China Chemistry 2023, 66 (4), 1150−1160. https://doi.org/10.1007/s11426-022-1441-7
112.  Yuanzhen Su#, Weiguo Xu#, Qi Wei, Yang Ma, Jianxun Ding*, Xuesi Chen, Chiral Polypeptide Nanoparticles as Nanoadjuvants of Nanovaccines for Efficient Cancer Prevention and Therapy. Science Bulletin 2023, 68 (3), 284−294. https://doi.org/10.1016/j.scib.2023.01.024
111.  Yang Liu#, Zhongyu Jiang#, Shizheng Tong, Yifu Sun, Yu Zhang, Jiayuan Zhang, Duoyi Zhao, Yuanzhen Su, Jianxun Ding*, Xuesi Chen*, Acidity-Triggered Transformable Polypeptide Self-Assembly to Initiate Tumor-Specific Biomineralization. Advanced Materials 2023, 35 (15), 2203291. https://doi.org/10.1002/adma.202203291 (Back Cover) https://doi.org/10.1002/adma.202370110
110.  Di Li, Siqi Liu, Yang Ma, Shixian Liu, Yahui Liu*, Jianxun Ding*,  Biomaterials That Induce Immunogenic Cell Death. Small Methods 2023, 7 (5), 2300204. https://doi.org/10.1002/smtd.202300204


2022
109.  Jin Zhang#, Dongmei Tong#, Honghai Song#, Renjie Ruan, Yifu Sun, Yandai Lin, Jun Wang, Linxi Hou, Jiayong Dai*, Jianxun Ding*, Huanghao Yang*, Osteoimmunity-Regulating Biomimetically Hierarchical Scaffold for Augmented Bone Regeneration. Advanced Materials 2022, 34 (36), 2202044. https://doi.org/10.1002/adma.202202044 (Inside Back Cover) https://doi.org/10.1002/adma.202270257 (ESI Hot Paper)
108.  Tongtong Zhu, Mengyang Jiang, Mingran Zhang, Liguo Cui, Xiaoyu Yang, Xukai Wang, Guangyao Liu*, Jianxun Ding*, Xuesi Chen, Biofunctionalized Composite Scaffold to Potentiate Osteoconduction, Angiogenesis, and Favorable Metabolic Microenvironment for Osteonecrosis Therapy. Bioactive Materials 2022, 9, 446−460. https://doi.org/10.1016/j.bioactmat.2021.08.005
107.  Mingran Zhang, Jiaxue Liu, Tongtong Zhu, Hanxiang Le, Xukai Wang, Jinshan Guo*, Guangyao Liu*, Jianxun Ding*, Functional Macromolecular Adhesives for Bone Fracture Healing. ACS Applied Materials & Interfaces 2022, 14 (1), 1−19. https://doi.org/10.1021/acsami.1c17434
106.  Jin Zhang, Yandai Lin, Zhe Lin, Qi Wei, Jiaqi Qian, Renjie Ruan, Xiancai Jiang, Linxi Hou, Jibin Song*, Jianxun Ding*, Huanghao Yang*, Stimuli-Responsive Nanoparticles for Controlled Drug Delivery in Synergistic Cancer Immunotherapy. Advanced Science 2022, 9 (5), 2103444. https://doi.org/10.1002/advs.202103444
105.  Tianqi Su, Xiangru Feng, Jiazhen Yang, Weiguo Xu, Tongjun Liu*, Minglei Zhang*, Jianxun Ding*, Xuesi Chen, Polymer Nanotherapeutics to Correct Autoimmunity. Journal of Controlled Release 2022, 343, 152−174. https://doi.org/10.1016/j.jconrel.2021.12.036
104.  Kai Liu, Lesan Yan, Ruotao Li, Zhiming Song, Jianxun Ding*, Bin Liu*, Xuesi Chen, 3D Printed Personalized Nerve Guide Conduits for Precision Repair of Peripheral Nerve Defects. Advanced Science 2022, 9 (12), 2103875. https://doi.org/10.1002/advs.202103875
103.  Zhongmin Li, Weiguo Xu, Jiazhen Yang, Juan Wang, Jialiang Wang, Ge Zhu, Di Li*, Jianxun Ding*, Tianmeng Sun*, Tumor Microenvironments-Adapted Polypeptide Hydrogel/Nanogel Composite Boosts Antitumor Molecular Targeted Inhibition and Immunoactivation. Advanced Materials 2022, 34 (21), 2200449. https://doi.org/10.1002/adma.202200449 (Back Cover) https://doi.org/10.1002/adma.202270162
102.  Zhongyu Jiang, Yang Liu, Run Shi, Xiangru Feng, Weiguo Xu, Xiuli Zhuang, Jianxun Ding*, Xuesi Chen, Versatile Polymer-Initiating Biomineralization for Tumor Blockade Therapy. Advanced Materials 2022, 34 (19), 2110094. https://doi.org/10.1002/adma.202110094 (Inside Back Cover) https://doi.org/10.1002/adma.202270146


2021
101.  Pan Zheng, Binbin Ding, Run Shi, Zhongyu Jiang, Weiguo Xu, Gao Li, Jianxun Ding*, Xuesi Chen, Multichannel Calcium Ion Nanomodulator for Multilevel Mitochondrial Destruction-Mediated Cancer Therapy. Advanced Materials 2021, 33 (15), 2007426. https://doi.org/10.1002/adma.202007426 (ESI Highly Cited Paper)
100.  Pan Zheng, Binbin Ding, Zhongyu Jiang, Weiguo Xu, Gao Li, Jianxun Ding*, Xuesi Chen*, Ultrasound-Augmented Mitochondrial Calcium Ion Overload by Calcium Nanomodulator to Induce Immunogenic Cell Death. Nano Letters 2021, 21 (5), 2088−2093. https://doi.org/10.1021/acs.nanolett.0c04778 (ESI Highly Cited Paper)
99.  Duoyi Zhao, Tongtong Zhu, Jie Li, Liguo Cui*, Zhiyu Zhang, Xiuli Zhuang, Jianxun Ding*, Poly(lactic-co-glycolic acid)-Based Composite Bone-Substitute Materials. Bioactive Materials 2021, 6 (2), 346−360. https://doi.org/10.1016/j.bioactmat.2020.08.016 (ESI Hot Paper)
98.  Duoyi Zhao, Xu Huang, Zhiyu Zhang, Jianxun Ding*, Yan Cui*, Xuesi Chen, Engineered Nanomedicines for Tumor Vasculature Blockade Therapy. WIREs Nanomedicine and Nanobiotechnology 2021, 13 (3), e1691. https://doi.org/10.1002/wnan.1691
97.  Jin Zhang, Xi Zhang, Chenyu Wang, Feihan Li, Ziwen Qiao, Liangdan Zeng, Zhonghan Wang, He Liu*, Jianxun Ding*, Huanghao Yang*, Conductive Composite Fiber with Optimized Alignment Guides Neural Regeneration under Electrical Stimulation. Advanced Healthcare Materials 2021, 10 (3), 2000604. https://doi.org/10.1002/adhm.202000604
96.  Jin Zhang#, Chunsheng Xiao#, Xi Zhang#, Yandai Lin, Huanghao Yang*, Yu Shrike Zhang*, Jianxun Ding*, An Oxidative Stress-Responsive Electrospun Polyester Membrane Capable of Releasing Anti-Bacterial and Anti-Inflammatory Agents for Postoperative Anti-Adhesion. Journal of Controlled Release 2021, 335, 359−368. https://doi.org/10.1016/j.jconrel.2021.04.017
95.  Jiazhen Yang, Haoyang Zou, Jianxun Ding*, Xuesi Chen, Controlled Synthesis and Biomedical Applications of Cystine-Based Polypeptide Nanomaterials. Acta Polymerica Sinica 2021, 52 (8), 960−977. DOI: 10.11777/j.issn1000-3304.2021.21115
94.  Juan Wang#, Weiguo Xu#, Ning Zhang#, Changsheng Yang, Hengwei Xu, Zhongtang Wang, Baosheng Li*, Jianxun Ding*, Xuesi Chen, X-Ray-Responsive Polypeptide Nanogel for Concurrent Chemoradiotherapy. Journal of Controlled Release 2021, 332, 1−9. https://doi.org/10.1016/j.jconrel.2021.02.003 (ESI Highly Cited Paper) (Inside Front Cover)
93.  Yajie Sun, Xiangru Feng, Chao Wan, Jonathan F. Lovell, Honglin Jin∗, Jianxun Ding*, Role of Nanoparticle-Mediated Immunogenic Cell Death in Cancer Immunotherapy. Asian Journal of Pharmaceutical Sciences 2021, 16 (2), 129−132. https://doi.org/10.1016/j.ajps.2020.05.004 (ESI Highly Cited Paper)
92.  Ziwen Qiao#, Xueli Lv#, Shaohua He#, Shumeng Bai, Xiaochen Liu, Linxi Hou, Jingjing He, Dongmei Tong, Renjie Ruan, Jin Zhang*, Jianxun Ding*, Huanghao Yang*, A Mussel-Inspired Supramolecular Hydrogel with Robust Tissue Anchor for Rapid Hemostasis of Arterial and Visceral Bleedings. Bioactive Materials 2021, 6 (9), 2829−2840. https://doi.org/10.1016/j.bioactmat.2021.01.039 (ESI Hot Paper)
91.  Wen Ma, Qiling Chen, Weiguo Xu, Meng Yu, Yuanyuan Yang, Binhua Zou, Yu Shrike Zhang*, Jianxun Ding*, Zhiqiang Yu*, Self-Targeting Visualizable Hyaluronate nanogel for Synchronized Intracellular Release of Doxorubicin and Cisplatin in Combating Multidrug-Resistant Breast Cancer. Nano Research 2021, 14 (3), 846−857. https://doi.org/10.1007/s12274-020-3124-y
90.  Jianhua Liu, Xu Huang*, Jianxun Ding*, Identification of MSA-2: An Oral Antitumor Non-Nucleotide STING Agonist. Signal Transduction and Targeted Therapy 2021, 6 (1), 18. https://doi.org/10.1038/s41392-020-00459-2
89.  Yao-Xin Lin#, Yi Wang#, Jianxun Ding, Aiping Jiang, Jie Wang, Mian Yu, Sara Blake, Shuaishuai Liu, Charles J. Bieberich, Omid C. Farokhzad*, Lin Mei*, Hao Wang*, Jinjun Shi*, Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models. Science Translational Medicine 2021, 13 (599), eaba9772. DOI: 10.1126/scitranslmed.aba9772
88.  Xu Huang, Weiguo Xu, Mingqiang Li, Ping Zhang, Yu Shrike Zhang*, Jianxun Ding*, Xuesi Chen, Antiviral Biomaterials. Matter 2021, 4 (6), 1892−1918. https://doi.org/10.1016/j.matt.2021.03.016
87.  Xiangru Feng, Weiguo Xu, Xiaoru Xu, Gao Li, Jianxun Ding*, Xuesi Chen, Cystine Proportion Regulates Fate of Polypeptide Nanogel as Nanocarrier for Chemotherapeutics. Science China Chemistry 2021, 64 (2), 293−301. https://doi.org/10.1007/s11426-020-9884-6 (Front Cover)
86.  Xiangru Feng, Weiguo Xu, Jianhua Liu, Di Li, Gao Li, Jianxun Ding*, Xuesi Chen, Polypeptide Nanoformulation-Induced Immunogenic Cell Death and Remission of Immunosuppression for Enhanced Chemoimmunotherapy. Science Bulletin 2021, 66 (4), 362−373. https://doi.org/10.1016/j.scib.2020.07.013 (ESI Highly Cited Paper)
85.  Jinjin Chen, Zhongyu Jiang, Yu Shrike Zhang, Jianxun Ding*, Xuesi Chen, Smart Transformable Nanoparticles for Enhanced Tumor Theranostics. Applied Physics Reviews 2021, 8 (4), 041321. https://doi.org/10.1063/5.0061530


2020
84.  Tongtong Zhu, Yutao Cui, Mingran Zhang, Duoyi Zhao, Guangyao Liu∗, Jianxun Ding, Engineered Three-Dimensional Scaffolds for Enhanced Bone Regeneration in Osteonecrosis. Bioactive Materials 2020, 5 (3), 584−601. https://doi.org/10.1016/j.bioactmat.2020.04.008 (ESI Hot Paper)
83.  Pan Zheng, Yang Liu, Jinjin Chen, Weiguo Xu, Gao Li, Jianxun Ding*, Targeted pH-Responsive Polyion Complex Micelle for Controlled Intracellular Drug Delivery. Chinese Chemical Letters 2020, 31 (5), 1178−1182. https://doi.org/10.1016/j.cclet.2019.12.001 (ESI Hot Paper) (Front Cover)
82.  Xi Zhang, Wenrui Qu*, Di Li, Kai Shi, Rui Li*, Yanqiu Han, E Jin, Jianxun Ding*, Xuesi Chen, Functional Polymer-Based Nerve Guide Conduits to Promote Peripheral Nerve Regeneration. Advanced Materials Interfaces 2020, 7 (14), 2000225. https://doi.org/10.1002/admi.202000225 (Back Cover) https://doi.org/10.1002/admi.202070081
81.  Qingqing Xiong, Yujing Li, Kun Zhou, Ping Chen, Hua Guo, Lu Chen, Jianxun Ding*, Tianqiang Song*, Jinjun Shi, Optimized Fluorodendrimer-Incorporated Hybrid Lipid–Polymer Nanoparticles for Efficient siRNA Delivery. Biomaterials Science 2020, 8 (3), 758−762. https://doi.org/10.1039/C9BM01738K
80.  Juan Wang, Zhongmin Li, Zhongtang Wang, Yonghua Yu*, Di Li, Baosheng Li*, Jianxun Ding*, Nanomaterials for Combinational Radio-Immuno Oncotherapy. Advanced Functional Materials 2020, 30 (30), 1910676. https://doi.org/10.1002/adfm.201910676
79.  Heping Qiu, Hui Guo, Di Li, Yuchuan Hou, Tairong Kuang*, and Jianxun Ding*, Intravesical Hydrogels as Drug Reservoirs. Trends in Biotechnology 2020, 38 (6), 579−583. https://doi.org/10.1016/j.tibtech.2019.12.012
78.  Yujing Li#, Jianxun Ding#, Xiaoding Xu#, Run Shi#, Phei Er Saw, Junqing Wang, Shirley Chung, Wenliang Li, Bader M. Aljaeid, Robert J. Lee, Wei Tao, Lesheng Teng*, Omid C. Farokhzad*, Jinjun Shi*, Dual Hypoxia-Targeting RNAi Nanomedicine for Precision Cancer Therapy. Nano Letters 2020, 20 (7), 4857−4863. https://doi.org/10.1021/acs.nanolett.0c00757
77.  Zhongyu Jiang, Xiangru Feng, Weiguo Xu, Xiuli Zhuang, Jianxun Ding*, Xuesi Chen, Calcium Phosphate-Cured Nanocluster of Poly(L-glutamic acid)-Cisplatin and Arsenic Trioxide for Synergistic Chemotherapy of Peritoneal Metastasis of Ovarian Cancer. Acta Polymerica Sinica 2020, 51 (8), 901−910. DOI: 10.11777/j.issn1000-3304.2020.20053
76.  Liguo Cui, Jin Zhang, Jun Zou, Xianrui Yang, Hui Guo, Huayu Tian, Peibiao Zhang, Yu Wang, Ning Zhang, Xiuli Zhuang, Zhongming Li, Jianxun Ding*, Xuesi Chen*, Electroactive Composite Scaffold with Locally Expressed Osteoinductive Factor for Synergistic Bone Repair upon Electrical Stimulation. Biomaterials 2020, 230, 119617. https://doi.org/10.1016/j.biomaterials.2019.119617 (ESI Highly Cited Paper)
75.  Jinjin Chen#, Zhongyu Jiang#, Weiguo Xu, Tianmen Sun, Xiuli Zhuang, Jianxun Ding*, Xuesi Chen*, Spatiotemporally Targeted Nanomedicine Overcomes Hypoxia-Induced Drug Resistance of Tumor Cells after Disrupting Neovasculature. Nano Letters 2020, 20 (8), 6191−6198. https://doi.org/10.1021/acs.nanolett.0c02515


2019
74.  Yanbo Zhang, Jiakuo Yu, Kaixuan Ren*, Jianlin Zuo*, Jianxun Ding*, and Xuesi Chen, Thermosensitive Hydrogels as Scaffolds for Cartilage Tissue Engineering. Biomacromolecules 2019, 20 (4), 1478−1492. https://doi.org/10.1021/acs.biomac.9b00043 (ESI Highly Cited Paper) (Front Cover)
73.  Yanbo Zhang, Xiaochen Liu, Liangdan Zeng, Jin Zhang*, Jianlin Zuo*, Jun Zou*, Jianxun Ding*, Xuesi Chen, Polymer Fiber Scaffolds for Bone and Cartilage Tissue Engineering. Advanced Functional Materials 2019, 29 (36), 1903279. https://doi.org/10.1002/adfm.201903279 (ESI Highly Cited Paper) (Inside Front Cover) https://doi.org/10.1002/adfm.201970246
72.  Qingzheng Zhang#, Bo Shi#, Jianxun Ding#, Lesan Yan#, Jayesh P. Thawani, Changfeng Fu*, Xuesi Chen, Polymer Scaffolds Facilitate Spinal Cord Injury Repair. Acta Biomaterialia 2019, 88, 57−77. https://doi.org/10.1016/j.actbio.2019.01.056
71.  Yingjie Yu#, Quan Xu#, Shasha He, Hejian Xiong, Qingfei Zhang, Weiguo Xu, Vincent Ricotta, Lei Bai, Qi Zhang, Zhiqiang Yu, Jianxun Ding*, Haihua Xiao*, Dongfang Zhou*, Recent Advances in Delivery of Photosensitive Metal-Based Drugs. Coordination Chemistry Reviews 2019, 387, 154−179. https://doi.org/10.1016/j.ccr.2019.01.020 (ESI Highly Cited Paper)
70.  Jing Xu, Hongsheng Wang, Yi Hu, Yu Shrike Zhang, Longping Wen, Fei Yin, Zhuoying Wang, Yingchao Zhang, Suoyuan Li, Yanyan Miao, Binhui Lin, Dongqing Zuo, Gangyang Wang, Min Mao, Tao Zhang, Jianxun Ding*, Yingqi Hua*, Zhengdong Cai*, Inhibition of CaMKIIα Activity Enhances Antitumor Effect of Fullerene C60 Nanocrystals by Suppression of Autophagic Degradation. Advanced Science 2019, 6 (8), 1801233. https://doi.org/10.1002/advs.201801233 (Back Cover) https://doi.org/10.1002/advs.201970051
69.  Yue Wang, Zhongyu Jiang, Weiguo Xu, Yanan Yang*, Xiuli Zhuang, Jianxun Ding*, Xuesi Chen, Chiral Polypeptide Thermogels Induce Controlled Inflammatory Response as Potential Immunoadjuvants. ACS Applied Materials & Interfaces 2019, 11 (9), 8725−8730. https://doi.org/10.1021/acsami.9b01872
68.  Qilong Wang, Ping Zhang*, Zhongmin Li*, Xiangru Feng, Chengyue Lv, Huaiyu Zhang, Haihua Xiao, Jianxun Ding*, Xuesi Chen, Evaluation of Polymer Nanoformulations in Hepatoma Therapy by Established Rodent Models. Theranostics 2019, 9 (5), 1426−1452. https://www.thno.org/v09p1426.htm (ESI Highly Cited Paper)
67.  Chenyu Wang, Jun Wang, Liangdan Zeng, Ziwen Qiao, Xiaochen Liu, He Liu, Jin Zhang*, Jianxun Ding, Fabrication of Electrospun Polymer Nanofibers with Diverse Morphologies. Molecules 2019, 24 (5), 834. https://doi.org/10.3390/molecules24050834 (ESI Highly Cited Paper)
66.  Chenyu Wang, Naibo Feng, Fei Chang, Jincheng Wang, Baoming Yuan, Yilong Cheng*, He Liu*, Jiakuo Yu, Jun Zou*, Jianxun Ding*, Xuesi Chen, Injectable Cholesterol-Enhanced Stereocomplex Polylactide Thermogel Loading Chondrocytes for Optimized Cartilage Regeneration. Advanced Healthcare Materials 2019, 8 (14), 1900312. https://doi.org/10.1002/adhm.201900312 (Front Cover) https://doi.org/10.1002/adhm.201970056
65.  Cong Ning#, Ying Guo#, Lesan Yan, Jayesh P. Thawani, Wenjing Zhang, Changfeng Fu*, Tiecheng Liu*, Jianxun Ding*, On-Demand Prolongation of Peripheral Nerve Blockade through Bupivacaine-Loaded Hydrogels with Suitable Residence Periods. ACS Biomaterials Science & Engineering 2019, 5 (2), 696−709. https://doi.org/10.1021/acsbiomaterials.8b01107
64.  Shengxian Li#, Xiangru Feng#, Jixue Wang, Weiguo Xu, Mohammad Ariful Islam, Tianmeng Sun, Zhigang Xie, Chunxi Wang, Jianxun Ding*, Xuesi Chen, Multiantigenic Nanoformulations Activate Anticancer Immunity Depending on Size. Advanced Functional Materials 2019, 29 (49), 1903391. https://doi.org/10.1002/adfm.201903391 (Inside Back Cover) https://doi.org/10.1002/adfm.201970336
63.  Yu Han#, Xuezhou Li#, Yanbo Zhang*, Yuping Han*, Fei Chang*, Jianxun Ding, Mesenchymal Stem Cells for Regenerative Medicine. Cells 2019, 8 (8), 886. https://doi.org/10.3390/cells8080886 (ESI Hot Paper)
62.  Xiangru Feng, Weiguo Xu, Zhongmin Li, Wantong Song, Jianxun Ding*, Xuesi Chen, Immunomodulatory Nanosystems. Advanced Science 2019, 6 (17), 1900101. https://doi.org/10.1002/advs.201900101 (Inside Front Cover) https://doi.org/10.1002/advs.201970100
61.  Xiangru Feng#, Jiannan Li#, Xi Zhang#, Tongjun Liu, Jianxun Ding*, Xuesi Chen, Electrospun Polymer Micro/Nanofibers as Pharmaceutical Repositories for Healthcare. Journal of Controlled Release 2019, 302, 19−41. https://doi.org/10.1016/j.jconrel.2019.03.020 (ESI Hot Paper)
60.  Jianxun Ding*, Jin Zhang*, Jiannan Li, Di Li, Chunsheng Xiao, Haihua Xiao*, Huanghao Yang, Xiuli Zhuang, Xuesi Chen*, Electrospun Polymer Biomaterials. Progress in Polymer Science 2019, 90, 1−34. https://doi.org/10.1016/j.progpolymsci.2019.01.002 (ESI Highly Cited Paper)
59.  Jianxun Ding*, Xiangru Feng, Zhongyu Jiang, Weiguo Xu, Hui Guo, Xiuli Zhuang, Xuesi Chen*, Polymer-Mediated Penetration-Independent Cancer Therapy. Biomacromolecules 2019, 20 (12), 4258−4271. https://doi.org/10.1021/acs.biomac.9b01263
58.  Jianxun Ding#, Jinjin Chen#, Liqian Gao#, Zhongyu Jiang, Yu Zhang, Mingqiang Li, Qicai Xiao, Su Seong Lee*, Xuesi Chen*, Engineered Nanomedicines with Enhanced Tumor Penetration. Nano Today 2019, 29, 100800. https://doi.org/10.1016/j.nantod.2019.100800 (ESI Hot Paper)


2018
57.  Yanbo Zhang, Jin Zhang, Weiguo Xu, Gao Xiao, Jianxun Ding*, Xuesi Chen, Tumor Microenvironment-Labile Polymer−Doxorubicin Conjugate Thermogel Combined with Docetaxel for in situ Synergistic Chemotherapy of Hepatoma. Acta Biomaterialia 2018, 77, 63−73. https://doi.org/10.1016/j.actbio.2018.07.021
56.  Yunjiao Zhang#, Rui Sha#, Lan Zhang#, Peipei Jin, Weiguo Xu, Jianxun Ding, Jun Lin, Jing Qian, Rui Zhang, Fanchen Luo, Jie Zeng*, Longping Wen*, Harnessing Copper-Palladium Alloy TetrapodNanoparticle-induced Pro-survival Autophagy for Optimized Photothermal Therapy of Drug-resistant Cancer. Nature Communications 2018, 9 (1), 4236. https://doi.org/10.1038/s41467-018-06529-y
55.  Yi Zhang, Feng Wang, Mingqiang Li, Zhiqiang Yu, Ruogu Qi*, Jianxun Ding*, Zhiyu Zhang*, Xuesi Chen, Self-Stabilized Hyaluronate Nanogel for Intracellular Co-Delivery of Doxorubicin and Cisplatin to Osteosarcoma. Advanced Science 2018, 5 (5), 1700821. https://doi.org/10.1002/advs.201700821 (ESI Highly Cited Paper)
54.  Yi Zhang#, Lulu Cai#, Di Li#, Yeh-Hsing Lao, Dingzhuo Liu, Mingqiang Li*, Jianxun Ding*, Xuesi Chen, Tumor Microenvironment-Responsive Hyaluronate-Calcium Carbonate Hybrid Nanoparticle Enables Effective Chemotherapy for Primary and Advanced Osteosarcomas. Nano Research 2018, 11 (9), 4806−4822. https://doi.org/10.1007/s12274-018-2066-0
53.  Wenjing Zhang, Weiguo Xu, Cong Ning, Mingqiang Li, Guoqing Zhao, Weiqian Jiang, Jianxun Ding*, Xuesi Chen, Long-Acting Hydrogel/Microsphere Composite Sequentially Releases Dexmedetomidine and Bupivacaine for Prolonged Synergistic Analgesia. Biomaterials 2018, 181, 378−391. https://doi.org/10.1016/j.biomaterials.2018.07.051
52.  Wenjing Zhang, Cong Ning, Weiguo Xu, Hanze Hu, Mingqiang Li*, Guoqing Zhao*, Jianxun Ding*, Xuesi Chen, Precision-Guided Long-Acting Analgesia by Hydrogel-Immobilized Bupivacaine-Loaded Microsphere. Theranostics 2018, 8 (12), 3331−3347. https://www.thno.org/v08p3331.htm
51.  Haihua Xiao, Lesan Yan, Elizabeth M Dempsey, Wantong Song, Ruogu Qi, Wenliang, Li, Yubin Huang, Xiabin Jing, Dongfang Zhou*, Jianxun Ding*, Xuesi Chen*, Recent Progress in Polymer-Based Platinum Drug Delivery Systems. Progress in Polymer Science 2018, 87, 70−106. https://doi.org/10.1016/j.progpolymsci.2018.07.004
50.  He Liu, Yilong Cheng, Jinjin Chen, Fei Chang, Jincheng Wang, Jianxun Ding*, Xuesi Chen, Component Effect of Stem Cell-Loaded Thermosensitive Polypeptide Hydrogels on Cartilage Repair. Acta Biomaterialia 2018, 73, 103−111. https://doi.org/10.1016/j.actbio.2018.04.035
49.  Suoyuan Li#, Tao Zhang#, Weiguo Xu#, Jianxun Ding*, Fei Yin, Jing Xu, Wei Sun, Hongsheng Wang, Mengxiong Sun, Zhengdong Cai*, Yingqi Hua*, Sarcoma-Targeting Peptide-Decorated Polypeptide Nanogel Intracellularly Delivers Shikonin for Upregulated Osteosarcoma Necroptosis and Diminished Pulmonary Metastasis. Theranostics 2018, 8 (5), 1361−1375. https://www.thno.org/v08p1361.htm (ESI Highly Cited Paper)
48.  Shengxian Li, Xiangru Feng, Jixue Wang, Liang He, Chunxi Wang, Jianxun Ding*, Xuesi Chen, Polymer Nanoparticles as Adjuvants of Cancer Immunotherapy. Nano Research 2018, 11 (11), 5769−5786. https://doi.org/10.1007/s12274-018-2124-7
47.  Shuqiang Li*, Shujun Dong, Weiguo Xu, Shicheng Tu, Lesan Yan, Changwen Zhao, Jianxun Ding*, Xuesi Chen, Antibacterial Hydrogels. Advanced Science 2018, 5 (5), 1700527. https://doi.org/10.1002/advs.201700527 (ESI Highly Cited Paper)
46.  Jiannan Li, Weiguo Xu, Di Li, Tongjun Liu, Yu Shrike Zhang*, Jianxun Ding*, Xuesi Chen*, Locally Deployable Nanofiber Patch for Sequential Drug Delivery in Treatment of Primary and Advanced Orthotopic Hepatomas. ACS Nano 2018, 12 (7), 6685−6699. https://doi.org/10.1021/acsnano.8b01729
45.  Di Li, Xiangru Feng, Li Chen*, Jianxun Ding*, Xuesi Chen, One-Step Synthesis of Targeted Acid-Labile Polysaccharide Prodrug for Efficiently Intracellular Drug Delivery. ACS Biomaterials Science & Engineering 2018, 4 (2), 539−546. https://doi.org/10.1021/acsbiomaterials.7b00856
44.  Liang He, Weiguo Xu, Xiaoqiing Wang, Chunxi Wang*, Jianxun Ding*, Xuesi Chen, Polymer Micro/Nanocarrier-Assisted Synergistic Chemohormonal Therapy for Prostate Cancer. Biomaterials Science 2018, 6 (6), 1433−1444. https://doi.org/10.1039/C8BM00190A
43.  Hui Guo, Faping Li, Weiguo Xu, Jinjin Chen, Yuchuan Hou*, Chunxi Wang, Jianxun Ding*, Xuesi Chen, Mucoadhesive Cationic Polypeptide Nanogel with Enhanced Penetration for Efficient Intravesical Chemotherapy of Bladder Cancer. Advanced Science 2018, 5 (6), 1800004. https://doi.org/10.1002/advs.201800004 (ESI Highly Cited Paper)
42.  Naibo Feng, Modi Yang, Xiangru Feng, Yinan Wang, Fei Chang,* Jianxun Ding*, Reduction-Responsive Polypeptide Nanogel for Intracellular Drug Delivery in Relieving Collagen-Induced Arthritis. ACS Biomaterials Science & Engineering 2018, 4 (12), 4154−4162. https://doi.org/10.1021/acsbiomaterials.8b00738
41.  Yuwei Cong, Haihua Xiao, Hejian Xiong, Zigui Wang, Jianxun Ding, Chan Li, Xuesi Chen*, Xing-Jie Liang*, Dongfang Zhou*, Yubin Huang, Dual Drug Backboned Shattering Polymeric Theranostic Nanomedicine for Synergistic Eradication of Patient-Derived Lung Cancer. Advanced Materials 2018, 30, 1706220. https://doi.org/10.1002/adma.201706220 (ESI Highly Cited Paper)


2017
40.  Yuhao Zheng, Yilong Cheng, Jinjin Chen, Jianxun Ding*, Mingqiang Li, Chen Li, Jingcheng Wang*, Xuesi Chen, Injectable Hydrogel−Microsphere Construct with Sequential Degradation for Locally Synergistic Chemotherapy. ACS Applied Materials & Interfaces 2017, 9 (4), 3487−3496. https://doi.org/10.1021/acsami.6b15245
39.  Kaidong Zhao, Di Li, Weiguo Xu, Jianxun Ding*, Weiqian Jiang, Mingqiang Li*, Chunxi Wang*, Xuesi Chen, Targeted Hydroxyethyl Starch Prodrug for Inhibiting the Growth and Metastasis of Prostate Cancer. Biomaterials 2017, 116, 82−94. https://doi.org/10.1016/j.biomaterials.2016.11.030
38.  Jin Zhang, Ting Zheng, Emine Alarçin, Batzaya Byambaa, Xiaofei Guan, Jianxun Ding*, Yu Shrike Zhang*, Zhongming Li*, Porous Electrospun Fibers with Self-Sealing Functionality: An Enabling Strategy for Trapping Biomacromolecules. Small 2017, 13 (47), 1701949. https://doi.org/10.1002/smll.201701949 (Back Cover) https://doi.org/10.1002/smll.201770249
37.  Modi Yang#, Xiangru Feng#, Jianxun Ding*, Fei Chang, Xuesi Chen, Nanotherapeutics Relieve Rheumatoid Arthritis. Journal of Controlled Release 2017, 252, 108−124. https://doi.org/10.1016/j.jconrel.2017.02.032
36.  Modi Yang, Jianxun Ding*, Xiangru Feng, Fei Chang*, Yinan Wang, Zhongli Gao, Xiuli Zhuang, Xuesi Chen, Scavenger Receptor-Mediated Targeted Treatment of Collagen-Induced Arthritis by Dextran Sulfate−Methotrexate Prodrug. Theranostics 2017, 7 (1), 97−105. https://www.thno.org/v07p0097.htm
35.  Jie Wu, Kunxi Zhang, Xi Yu, Jianxun Ding*, Lei Cui*, Jingbo Yin*, Hydration of Hydrogels Regulates Vascularization in vivo. Biomaterials Science 2017, 5 (11), 2251−2267. https://doi.org/10.1039/C7BM00268H
34.  Lingyu Wei, Jinjin Chen, Shuhua Zhao, Jianxun Ding*, Xuesi Chen, Thermo-Sensitive Polypeptide Hydrogel for Locally Sequential Delivery of Two-Pronged Antitumor Drugs. Acta Biomaterialia 2017, 58, 44−53. https://doi.org/10.1016/j.actbio.2017.05.053
33.  Bo Shi#, Kexin Huang#, Jianxun Ding#, Weiguo Xu*, Yu Yang, Haiyan Liu*, Lesan Yan*, Xuesi Chen, Intracellularly Swollen Polypeptide Nanogel Assists Hepatoma Chemotherapy. Theranostics 2017, 7 (3), 703−716. https://www.thno.org/v07p0703.htm
32.  Jiannan Li, Xiangru Feng, Baichun Liu, Yingjie Yu, Leming Sun, Tongjun Liu*, Yongheng Wang, Jianxun Ding*, Xuesi Chen, Polymer Materials for Prevention of Postoperative Adhesion. Acta Biomaterialia 2017, 61, 21−40. https://doi.org/10.1016/j.actbio.2017.08.002
31.  Hui Guo, Weiguo Xu, Jinjin Chen, Lesan Yan, Jianxun Ding*, Yuchuan Hou*, Xuesi Chen*, Positively Charged Polypeptide Nanogel Enhances Mucoadhesion and Penetrability of 10-Hydroxycamptothecin in Orthotopic Bladder Carcinoma. Journal of Controlled Release 2017, 259, 136−148. https://doi.org/10.1016/j.jconrel.2016.12.041
30.  Xiangru Feng, Jianxun Ding*, Ruxandra Gref*, Xuesi Chen, Poly(β-cyclodextrin)-Mediated Polylactide-Cholesterol Stereocomplex Micelles for Controlled Drug Delivery. Chinese Journal of Polymer Science 2017, 35 (6), 693−699. https://doi.org/10.1007/s10118-017-1932-7 (Front Cover)
29.  Jinjin Chen#, Jianxun Ding#, Weiguo Xu, Tianmeng Sun, Haihua Xiao, Xiuli Zhuang, Xuesi Chen*, Receptor and Microenvironment Dual-Recognizable Nanogel for Targeted Chemotherapy of Highly Metastatic Malignancy. Nano Letters 2017, 17 (7), 4526−4533. https://doi.org/10.1021/acs.nanolett.7b02129
28.  Jinjin Chen, Jianxun Ding*, Yucai Wang, Jianjun Cheng*, Shengxiang Ji, Xiuli Zhuang, Xuesi Chen*, Sequentially Responsive Shell-Stacked Nanoparticles for Deep Penetration into Solid Tumors. Advanced Materials 2017, 29 (32), 1701170. https://doi.org/10.1002/adma.201701170 (ESI Highly Cited Paper)


2016
27.  Li Zhao, Chunsheng Xiao, Guangqing Gai, Liyan Wang, Jianxun Ding*, Glucose-Sensitive Polymer Nanoparticles for Self-Regulated Drug Delivery. Chemical Communications 2016, 52 (49), 7633−7652. https://doi.org/10.1039/C6CC02202B
26.  Zhengzheng Zhang#, Dong Jiang#, Jianxun Ding*, Shaojie Wang, Lei Zhang, Jiying Zhang, Yansong Qi, Xuesi Chen, Jiakuo Yu*, Role of Scaffold Mean Pore Size in Meniscus Regeneration. Acta Biomaterialia 2016, 43, 314−326. https://doi.org/10.1016/j.actbio.2016.07.050
25.  Jin Zhang#, He Liu#, Jianxun Ding*, Jie Wu, Xiuli Zhuang, Xuesi Chen, Jincheng Wang*, Jingbo Yin, Zhongming Li*, High-Pressure Compression-Molded Porous Resorbable Polymer/Hydroxyapatite Composite Scaffold for Cranial Bone Regeneration. ACS Biomaterials Science & Engineering 2016, 2 (9), 1471−1482. https://doi.org/10.1021/acsbiomaterials.6b00202
24.  Modi Yang, Jianxun Ding*, Ying Zhang, Fei Chang*, Jincheng Wang, Zhongli Gao*, Xiuli Zhuang, Xuesi Chen, Activated Macrophage-Targeted Dextran-Methotrexate/Folate Conjugate Prevents Deterioration of Collagen-Induced Arthritis in Mice. Journal of Materials Chemistry B 2016, 4 (12), 2102−2113. https://doi.org/10.1039/C5TB02479J
23.  Zhaohui Tang, Chaoliang He, Huayu Tian, Jianxun Ding, Benjamin S. Hsiao*, Benjamin Chu, Xuesi Chen*, Polymeric Nanostructured Materials for Biomedical Applications. Progress in Polymer Science 2016, 60, 86−128. https://doi.org/10.1016/j.progpolymsci.2016.05.005 (ESI Highly Cited Paper)
22.  Xuezhou Li, Jianxun Ding*, Zhengzheng Zhang, Modi Yang, Jiakuo Yu, Jincheng Wang*, Fei Chang*, Xuesi Chen*, Kartogenin-Incorporated Thermogel Supports Stem Cells for Significant Cartilage Regeneration. ACS Applied Materials & Interfaces 2016, 8 (8), 5148−5159. https://doi.org/10.1021/acsami.5b12212
21.  Di Li, Weiguo Xu, Pengqiang Li, Jianxun Ding*, Zhiliang Cheng, Li Chen, Lesan Yan*, Xuesi Chen, Self-Targeted Polysaccharide Prodrug Suppresses Orthotopic Hepatoma. Molecular Pharmaceutics 2016, 13 (12), 4231−4235. https://doi.org/10.1021/acs.molpharmaceut.6b00747
20.  Taoyuan He, Di Li, Yanan Yang*, Jianxun Ding*, Feng Jin, Xiuli Zhuang, Xuesi Chen, Mesomeric Configuration Makes Polyleucine Micelle an Optimal Nanocarrier. Biomaterials Science 2016, 4 (5), 814−818. https://doi.org/10.1039/C6BM00022C


2015
19.  Weiguo Xu, Jianxun Ding*, Chunsheng Xiao, Lingyu Li, Xiuli Zhuang, Xuesi Chen*, Versatile Preparation of Intracellular-Acidity-Sensitive Oxime-Linked Polysaccharide-Doxorubicin Conjugate for Malignancy Therapeutic. Biomaterials 2015, 54, 72−86. https://doi.org/10.1016/j.biomaterials.2015.03.021 (ESI Highly Cited Paper)
18.  He Liu#, Jianxun Ding#, Chenyu Wang, Jincheng Wang*, Yinan Wang*, Modi Yang, Yunlong Jia, Yanbo Zhang, Fei Chang*, Rui Li, Xuesi Chen, Intra-Articular Transplantation of Allogeneic BMMSCs Rehabilitates Cartilage Injury of Antigen-Induced Arthritis. Tissue Engineering Part A 2015, 21 (21-22), 2733−2743. https://doi.org/10.1089/ten.tea.2014.0666
17.  Kexin Huang, Bo Shi, Weiguo Xu, Jianxun Ding*, Yu Yang, Haiyan Liu*, Xiuli Zhuang, Xuesi Chen, Reduction-Responsive Polypeptide Nanogel Delivers Antitumor Drug for Improved Efficacy and Safety. Acta Biomaterialia 2015, 27, 179−193. https://doi.org/10.1016/j.actbio.2015.08.049
16.  Jinjin Chen#, Jianxun Ding#, Ying Zhang, Chunsheng Xiao, Xiuli Zhuang, Xuesi Chen*, Polyion Complex Micelles with Gradient pH-Sensitivity for Adjustable Intracellular Drug Delivery. Polymer Chemistry 2015, 6 (3), 397−405. https://doi.org/10.1039/C4PY01149J
15.  Jinjin Chen, Jianxun Ding*, Chunsheng Xiao, Xiuli Zhuang, Xuesi Chen*, Emerging Antitumor Applications of Extracellularly Reengineered Polymeric Nanocarriers. Biomaterials Science 2015, 3 (7), 988−1001. https://doi.org/10.1039/C5BM00044K


2014
14.  Shuangjiang Yu#, Jianxun Ding#, Chaoliang He*, Yue Cao, Weiguo Xu, Xuesi Chen, Disulfide Cross-Linked Polyurethane Micelles as a Reduction-Triggered Drug Delivery System for Cancer Therapy. Advanced Healthcare Materials 2014, 3 (5), 752−760. https://doi.org/10.1002/adhm.201300308
13.  Diankui Sun, Jianxun Ding*, Chunsheng Xiao, Jinjin Chen, Xiuli Zhuang*, Xuesi Chen, Preclinical Evaluation of Antitumor Activity of Acid-Sensitive PEGylated Doxorubicin. ACS Applied Materials & Interfaces 2014, 6 (23), 21202−21214. https://doi.org/10.1021/am506178c
12.  Jianxun Ding, Linghui Chen, Chunsheng Xiao, Li Chen, Xiuli Zhuang, Xuesi Chen*, Noncovalent Interaction-Assisted Polymeric Micelles for Controlled Drug Delivery. Chemical Communications 2014, 50 (77), 11274−11290. https://doi.org/10.1039/C4CC03153A


2013
11.  Di Li#, Hai Sun#, Jianxun Ding*, Zhaohui Tang*, Ying Zhang, Weiguo Xu, Xiuli Zhuang, Xuesi Chen, Polymeric Topology and Composition Constrained Polyether-Polyester Micelles for Directional Antitumor Drug Delivery. Acta Biomaterialia 2013, 9 (11), 8875−8884. https://doi.org/10.1016/j.actbio.2013.06.041
10.  Jianxun Ding, Li Zhao, Di Li, Chunsheng Xiao*, Xiuli Zhuang*, Xuesi Chen, Thermo-Responsive "Hairy-Rod" Polypeptides for Smart Antitumor Drug Delivery. Polymer Chemistry 2013, 4 (11), 3345−3356. https://doi.org/10.1039/C3PY00144J
9.  Jianxun Ding, Weiguo Xu, Ying Zhang, Diankui Sun, Chunsheng Xiao*, Donghong Liu, Xiaojuan Zhu*, Xuesi Chen*, Self-Reinforced Endocytoses of Smart Polypeptide Nanogels for "On-Demand" Drug Delivery. Journal of Controlled Release 2013, 172 (2), 444−455. https://doi.org/10.1016/j.jconrel.2013.05.029
8.  Jianxun Ding, Chunsheng Xiao, Yuce Li, Yilong Cheng, Nannan Wang, Chaoliang He, Xiuli Zhuang*, Xiaojuan Zhu*, Xuesi Chen*, Efficacious Hepatoma-Targeted Nanomedicine Self-Assembled from Galactopeptide and Doxorubicin Driven by Two-Stage Physical Interactions. Journal of Controlled Release 2013, 169 (3), 193−203. https://doi.org/10.1016/j.jconrel.2012.12.006
7.  Jianxun Ding#, Fenghua Shi#, Di Li, Li Chen*, Xiuli Zhuang*, Xuesi Chen, Enhanced Endocytosis of Acid-Sensitive Doxorubicin Derivatives with Intelligent Nanogel for Improved Security and Efficacy. Biomaterials Science 2013, 1 (6), 633−646. https://doi.org/10.1039/C3BM60024F
6.  Jianxun Ding, Jinjin Chen, Di Li, Chunsheng Xiao, Jiancheng Zhang, Chaoliang He, Xiuli Zhuang*, Xuesi Chen*, Biocompatible Reduction-Responsive Polypeptide Micelles as Nanocarriers for Enhanced Chemotherapy Efficacy in vitro. Journal of Materials Chemistry B 2013, 1 (1), 69−81. https://doi.org/10.1039/C2TB00063F (ESI Highly Cited Paper)


2012
5.  Li Zhao#, Jianxun Ding#, Chunsheng Xiao, Pan He, Zhaohui Tang, Xuan Pang, Xiuli Zhuang, Xuesi Chen, Glucose-Sensitive Polypeptide Micelles for Self-Regulated Insulin Release at Physiological pH. Journal of Materials Chemistry 2012, 22, 12319−12328. https://doi.org/10.1039/C2JM31040F
4.  Fenghua Shi#, Jianxun Ding#, Chunsheng Xiao, Xiuli Zhuang*, Chaoliang He, Li Chen*, Xuesi Chen, Intracellular Microenvironment Responsive PEGylated Polypeptide Nanogels with Ionizable Cores for Efficient Doxorubicin Loading and Triggered Release. Journal of Materials Chemistry 2012, 22, 14168−14179. https://doi.org/10.1039/C2JM32033A


2011
3.  Jianxun Ding, Xiuli Zhuang, Chunsheng Xiao, Yilong Cheng, Li Zhao, Chaoliang He, Zhaohui Tang, Xuesi Chen*, Preparation of Photo-Cross-Linked pH-Responsive Polypeptide Nanogels as Potential Carriers for Controlled Drug Delivery. Journal of Materials Chemistry 2011, 21, 11383−11391. https://doi.org/10.1039/C1JM10391A
2.  Jianxun Ding, Fenghua Shi, Chunsheng Xiao, Lin Lin, Li Chen*, Chaoliang He, Xiuli Zhuang*, Xuesi Chen, One-Step Preparation of Reduction-Responsive Poly(ethylene glycol)−Poly(amino acid)s Nanogels as Efficient Intracellular Drug Delivery Platforms. Polymer Chemistry 2011, 2, 2857−2864. https://doi.org/10.1039/C1PY00360G


2008
1.  Jing Cheng, Jianxun Ding, Yucai Wang, Jun Wang*, Synthesis and Characterization of Star-Shaped Block Copolymer of Poly(ε-caprolactone) and Poly(ethyl ethylene phosphate) as Drug Carrier. Polymer 2008, 49, 4784−4790. https://doi.org/10.1016/j.polymer.2008.08.052 

代表授权专利

31.  丁建勋 、郑盼、丁彬彬、李杲、陈学思，一种具有线粒体靶向功能的响应性纳米颗粒、其制备方法及应用，中国发明专利，ZL202010448455.5，授权日：2021-12-14，申请日：2020-05-25

30.  丁建勋、姜中雨、庄秀丽、陈学思，一种具有pH响应的顺式-二氯二氨合铂配合物、其制备方法及应用，中国发明专利，ZL201811580596.1，授权日：2021-11-05，申请日：2018-12-24

29.  丁建勋、郭辉、李鹏强、陈学思，一种纳米凝胶、其制备方法和抗肿瘤载药纳米凝胶，中国发明专利，ZL201910333760.7，授权日：2021-08-17，申请日：2019-04-24

28.  丁建勋、姜中雨、庄秀丽、陈学思，一种具有ROS相应的顺式-二氯二氨合铂配合物、其制备方法及应用，中国发明专利，ZL201811580586.8，授权日：2021-07-02，申请日：2018-12-24

27.  丁建勋、姜中雨、许维国、庄秀丽、陈学思，一种具有诱导细胞钙化能力的化合物、其制备方法和应用，中国发明专利，ZL201911188252.0，授权日：2021-04-06，申请日：2019-11-28

26.  丁建勋、李建男、庄秀丽、陈学思，一种术后防粘连高分子薄膜及其制备方法，中国发明专利，ZL201710099623.2，授权日：2020-07-07，申请日：2017-02-23
25.  丁建勋、姜中雨、庄秀丽、陈学思，一种具有电荷可翻转的聚离子型胶束遮蔽体系及其制备方法，中国发明专利，ZL201711273925.3，授权日：2020-05-19，申请日：2017-12-06
24.  丁建勋、陈进进、魏伶羽、庄秀丽、陈学思，一种聚氨基酸嵌段共聚物及其制备方法和应用，中国发明专利，ZL201710344005.X，授权日：2019-09-13，申请日：2017-05-16
23.  丁建勋、张莹、肖春生、庄秀丽、陈学思，一种载药聚合物囊泡及其制备方法，中国发明专利，ZL201510367124.8，授权日：2018-08-28，申请日：2015-06-29
22.  丁建勋、何陶媛、庄秀丽、陈学思，一种聚氨基酸及其制备方法和载药胶束，中国发明专利，ZL201510526359.7，授权日：2018-07-27，申请日：2015-08-25
21.  丁建勋、卢升帆、庄秀丽、陈学思，一种葡聚糖-聚氨基酸嵌段共聚物及其制备方法和载药胶束，中国发明专利，ZL201510154807.5，授权日：2017-11-14，申请日：2015-04-02
20.  丁建勋、陈进进、肖春生、庄秀丽、陈学思，一种纳米凝胶、其制备方法和抗肿瘤纳米凝胶载药体系及其制备方法，中国发明专利，ZL201510190343.3，授权日：2017-08-25，申请日：2015-04-21
19.  丁建勋、孙殿奎、庄秀丽、陈学思，高分子阿霉素键合药及其制备方法，中国发明专利，ZL201410283678.5，授权日：2017-08-25，申请日：2014-06-23
18.  丁建勋、孙殿奎、庄秀丽、陈学思，一种阿霉素键合药及其制备方法、物理凝胶及其应用，中国发明专利，ZL201510106221.1，授权日：2017-07-07，申请日：2015-03-11
17.  丁建勋、陈进进、肖春生、庄秀丽、陈学思，一种肿瘤细胞靶向的纳米凝胶及其制备方法以及一种肿瘤细胞靶向的纳米凝胶载药颗粒，中国发明专利，ZL201510182250.6，授权日：2017-06-23，申请日：2015-04-17
16.  丁建勋、陈进进、庄秀丽、陈学思，一种逐级响应的纳米载体、其制备方法及其应用，中国发明专利，ZL201510056996.2，授权日：2017-06-23，申请日：2015-02-04
15.  丁建勋、刘东红、庄秀丽、陈学思，聚乙二醇单甲醚-聚酯两嵌段共聚物胶束及载药胶束的制备方法，中国发明专利，ZL201310319355.2，授权日：2017-04-19，申请日：2013-07-26
14.  丁建勋、刘东红、庄秀丽、陈学思，非线性聚乙二醇-聚酯共聚物、非线性聚乙二醇-聚酯共聚物胶束及载药胶束的制备方法，中国发明专利，ZL201310319324.7，授权日：2017-03-29，申请日：2013-07-26
13.  丁建勋、卢升帆、庄秀丽、陈学思，一种双响应性葡聚糖-聚氨基酸嵌段共聚物及其制备方法和载药胶束，中国发明专利，ZL201510154772.5，授权日：2017-03-01，申请日：2015-04-02
12.  丁建勋、刘东红、陈学思、庄秀丽，聚乙二醇-聚酯三嵌段共聚物载药纳米胶束的制备方法，中国发明专利，ZL201310319370.7，授权日：2016-09-28，申请日：2013-07-26
11.  丁建勋、许维国、庄秀丽、陈学思，一种香菇多糖的提取及分级方法，中国发明专利，ZL201310753452.2，授权日：2016-08-24，申请日：2013-12-31
10.  丁建勋、陈进进、肖春生、庄秀丽、陈学思，一种表面电荷可转变的纳米凝胶及其制备方法以及一种表面电荷可转变的纳米凝胶载药颗粒，中国发明专利，ZL201510182230.9，授权日：2016-07-06，申请日：2015-04-17
9.  丁建勋、陈进进、庄秀丽、陈学思，一种响应性聚合物胶束载药体系及其制备方法，中国发明专利，ZL201410123013.8，授权日：2016-07-06，申请日：2014-03-28
8.  丁建勋、许维国、庄秀丽、陈学思，葡聚糖-阿霉素键合药及其制备方法，中国发明专利，ZL201310728141.0，授权日：2016-07-06，申请日：2013-12-25
7.  丁建勋、李忠明、张进、庄秀丽、陈学思，一种生物可降解的医用手术防粘连膜的制备方法，中国发明专利，ZL201410066463.8，授权日：2016-06-01，申请日：2014-02-26
6.  丁建勋、陈学思、庄秀丽，一种聚醚嵌段共聚物及其制备方法，中国发明专利，ZL201210363911.1，授权日：2015-10-07，申请日：2012-09-26
5.  丁建勋、许维国、庄秀丽、陈学思，透明质酸-阿霉素键合药及其制备方法，中国发明专利，ZL201310728226.9，授权日：2015-09-16，申请日：2013-12-25
4.  丁建勋、许维国、庄秀丽、陈学思，香菇多糖-阿霉素键合药及其制备方法，中国发明专利，ZL201310728210.8，授权日：2015-09-16，申请日：2013-12-25
3.  丁建勋、许维国、庄秀丽、陈学思，海藻酸-阿霉素键合药及其制备方法，中国发明专利，ZL201310728247.0，授权日：2015-08-05，申请日：2013-12-25
2.  丁建勋、肖冰、庄秀丽、陈学思，聚(γ-寡聚乙二醇单甲醚-L-谷氨酸酯)-聚氨基酸两嵌段共聚物及其制备方法，中国发明专利，ZL201210571599.5，授权日：2015-07-22，申请日：2012-12-25
1.  丁建勋、石丰华、庄秀丽、陈莉、陈学思，聚氨基酸嵌段共聚物的制备方法及聚氨基酸嵌段共聚物水凝胶，中国发明专利，ZL201210492369.X，授权日：2014-10-22，申请日：2012-11-27