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成果及论文

科研项目

国家自然科学基金委面上项目,22371259,双烯含氮中环的催化不对称跨环反应构建手性含氮稠合双环骨架研究,2024-01至2027-12,在研。

浙江省领军型创新创业团队(手性催化反应创新团队),2022R01007,不对称催化反应研究机制,2023-01至2025-12,在研(核心成员)

浙江省自然科学基金重点项目,LZ23B020003,基于高阶环加成策略的手性七元杂环稠环骨架的催化不对称构建,2023-01至2025-12,在研。

国家重点研发计划“发育编程及其代谢调节”重点专项,2021YFA0804900,心脑跨器官代谢调控,2022-01至2026-12,在研(参与)

国家自然科学基金委面上项目,22171082,手性八元杂环稠环骨架的催化不对称构建及其生理活性研究,2022-01至2025-12,在研。

国家自然科学基金委面上项目,21971062,新型不对称[4+3]环加成反应构建手性七元(杂)环并芳杂环骨架及其生理活性研究,2020-01至2023-12,在研。

国家自然科学基金委面上项目,21772038,亚甲胺叶立德参与的新型催化不对称[3+3]/[4+3]环加成反应研究,2018-01至2021-12,已结题。

国家自然科学基金委面上项目,21572053,新型螺吡咯类手性仲胺催化剂的设计合成及其应用研究,2016-01至2019-12,已结题。

国家自然科学基金委面上项目,21372074,新型手性含氮亲核催化剂的设计合成及应用,2014-01至2017-12,已结题。

上海市科委,战略性新兴产业引导专项,14431902500,新型三环骨架的组蛋白去乙酰化酶抑制剂抗肿瘤先导化合物的筛选研究,2014-10至2017-9,已结题。

国家自然科学基金委面上项目,21172068,基于二氢咪唑并喹啉骨架的新型N,O-配体的设计合成及其在不对称催化中的应用,2012-01至2015-12已结题。

国家自然科学基金委面上项目,20972047,二倍半萜类海洋天然产物Scalarafuran及其类似物的不对称全合成研究,2010-01至2012-12,已结题。

上海市科委,基础研究重点项目,09JC1404500,基于组蛋白去乙酰化酶的新型靶向小分子抗肿瘤先导化合物的发现,2009-9至2011-8,已结题。

上海市教委,曙光人才计划,09SG28,Scalarane型海洋天然产物的全合成及其生理活性研究,2010-01至2011-12,已结题。

教育部,新世纪优秀人才支持计划,NCET-07-0283,基于组蛋白去乙酰化酶的新型靶向手性小分子抗肿瘤先导化合物的设计合成及结构优化,2008-01至2010-12,已结题。


代表性论文(2010-)

2024

136. Jian Zhang, Jia-Yi Su, Hanliang Zheng, Hao Li,  Wei-Ping Deng. In(OTf)3‑Catalyzed (3 + 3) Dipolar Cyclization of Bicyclo[1.1.0]butanes with N‑Nucleophilic 1,3-Dipoles: Access to 2,3-Diazabicyclo[3.1.1]heptanes, 2,3-Diazabicyclo[3.1.1]heptenes, and Enantiopure 2‑Azabicyclo[3.1.1]heptanes. ACS Catal. 2024, 14, 17837−17849.



135. Xinhao Lu, Yi Wang, Chenghan He, Yang-Zi Liu, Wei-Ping Deng. Synthesis of Indole-Fused Eight-Membered Oxa-Ringsvia Palladium-Catalyzed Asymmetric [4+4] Cycloadditionof Indole-2,3-Quinodimethanes with 2-AlkylidenetrimethyleneCarbonates. 

Chin. J. Chem. 2024, 42, 3393-3398.



134. Jia-Yi Su, Jian Zhang, Zhi-Yun Xin, Hao Li, Hanliang Zheng, Wei-Ping Deng. Access to Spiro-bicyclo [2.1.1] hexanes via BF3∙ Et2O-Catalyzed Formal [2π+2σ] Cycloaddition of Bicyclo [1.1.0] butanes with Benzofuran-derived Oxa (aza) dienes. Org. Chem. FrontDOI: 10.1039/d4qo00511b



133. Ting-Peng Li, Shuixiu Su, Jia-Huan Shen, Meng Zang, Yang-Zi Liu, Quannan Wang and Wei-Ping Deng. Palladium-catalyzed asymmetric [4+3] cycloaddition of acyclic α, β-unsaturated imines with trimethylenemethane donors: access to chiral non-fused azepines. Org. Chem. Front. 2024, 11, 2326-2331.


132. Jian Zhang, Jia-Yi Su, Hanliang Zheng, Hao Li, Wei-Ping Deng. Eu(OTf)3‐Catalyzed Formal Dipolar [4π+2σ] Cycloaddition of Bicyclo‐[1.1. 0] butanes with Nitrones: Access to Polysubstituted 2‐Oxa‐3‐azabicyclo [3.1.1] heptanes. Angew. Chem. Int. Ed. 2024, e02318476.

2023

131.Tao Ye, Na Lin, Jia-Huan Shen, Lichun Kong, Yang-Zi Liu, Quannan Wang, Wei-Ping DengFerric nitrate-catalyzed aerobic oxidative ring-opening of substituted furans for the stereoselective synthesis of (Z)‑1,4 enediones.

 https://doi.org/10.1016/j.gresc.2023.11.007


130.Jun-Tao Chen, Na Lin, Linli Xu, Yi Wang, Xiaoyan Luo, Yang-Zi Liu and Wei-Ping DengPalladium-catalyzed [6 + 4] cycloaddition with π-allyl all-carbon 1,6-dipole for the synthesis of ten-membered heterocycles. DOI: 10.1039/d3qo01793a


129.Chenglong Hu, Xuyang Tang, Baochi Zhang, Zhenfeng Zhang, Wei-Ping Deng, and Wanbn Zhang. Thiourea-Assisted Chiral Bicyclic Imidazole Organocatalysts: Design, Synthesis, and Application in Asymmetric Acylative Desymmetrization of Bisphenols for the Construction of P‑Stereocenters. ACS Catal. 2023, 13, 16300−16306


128.Quannan Wang, Wei-Ping DengMerging Visible Light Photocatalysis and P(III)-Directed C—H Activation by a Single Catalyst: Modular Assembly of P-Alkyne Hybrid Ligands. Chin. J. Org. Chem. 2023, 43, 4305-4307


127.Jian Zhang , Jia-Yi Su , Yang-Zi Liu, Hao Li , Quannan Wang & Wei-Ping Deng; Palladium-catalyzed allylic alkylation enabled by ketone umpolung via Pudovik addition/[1,2]-phospha-Brook rearrangement. Sci China Chem, 2023, 66: 2810–2816

126. Zeng Daming, Zhao Suqin, Deng Wei-Ping, Jiang Xuefeng. SVI–C Linkage for Allylsulfonximines via BF3-Mediated Allylation. Org. Lett., 2023, 25, 5591-5596. https://doi.org/10.1021/acs.orglett.3c01902

125. Zeng Daming, Deng Wei-Ping, Jiang Xuefeng. Advances in the construction of diverse SuFEx linkers. Natl. Sci. Rev., 2023, 10(6), nwad123. https://doi.org/10.1093/nsr/nwad123

124. Zeng Daming, Deng Wei-Ping, Jiang Xuefeng. Linkage Chemistry of S(VI) Fluorides.  Chem. Eur. J., 2023, 29, e202300536.

 https://doi.org/10.1002/chem.202300536

123.Ying ChenMeng ZangWeijie WangYang-Zi LiuXiaoyan LuoWei-Ping Deng, Palladium-Catalyzed [4 + 4] Cycloaddition of Homo-TMM All-Carbon 1,4-Dipole Precursors for Construction of Benzofuro[3,2-b]azocines and Furo[3,2-b]azocines,Chin. J. Chem.2023, 41, 2825—2831


122. Wang Yi, Zhang Jian, Liu Yangzi, Luo Xiaoyan, Deng Weiping. Palladium-Catalyzed Asymmetric [3 + 4] Cycloadditions for the Construction of Cyclohepta[b]Indoles[J]. Chin. J. Org. Chem. 2023, 43

121. Ding Zhengdong, Gao Feng, Lu Yining, Yuan Qianjia, Deng Wei-Ping, Zhang Wanbin. Asymmetric Hydrogenation of Tetrasubstituted α,β-Unsaturated Ketones: Access to Chiral 2‑Substituted Cyclopentyl Aryl Ketones. Precis. Chem., 2023, DOI: 10.1021/prechem.2c00010.


120. Liu Wenqi, Zang Meng, Zhang Jian, Liu Yang-Zi, Wang Quannan, Deng Wei-Ping. Pd-Catalyzed exclusively regioselective [5+4] cycloaddition for the construction of 1,5-di/ox-azonanes. Org. Chem. Front., 2023,10, 1680-1685,DOI: 10.1039/D3QO00070 B.


119. Zhang Jian, Yao Lingyun, Su Jia-Yi, Liu Yang-Zi, Wang Quannan, Deng Wei-Ping. Transition-metal-catalyzed aromatic C–H functionalization assisted by the phosphorus-containing directing groups. Green Synth. Catal., 2023, DOI: 10.1016/j.gresc.2023.02. 001.


118. Ye Tao, Cheng Fangyuan, Zhang Jian, Liu Yang-Zi, Wang Quannan, Deng Wei-Ping. Highly regioselective C–H carbonylation of alkenes with phenyl formate via aryl to vinyl 1,4-palladium migration. Org. Chem. Front., 2023,10, 1537-1543DOI:10.1039/D3QO00066D.


2022

117. Zhang Jian, Chen Ying, Wang Quannan, Shen Jiahuan, Liu Yangzi, Deng Weiping. Transition Metal-Catalyzed Asymmetric Cyclizations Involving Allyl or Propargyl Heteroatom-Dipole Precursors. Chin. J. Org. Chem., 2022, 42(10), 3051-3101.


116. Zeng Daming, Ma Yinhao, Deng Wei-Ping, Wang Ming, Jiang Xuefeng. The Linkage of Sulfonimidoyl Fluorides and Unactivated Alkenes via Hydrosulfonimidoylation. Angew. Chem. Int. Ed., 2022, 61, e202207100. 


115. Yang Wu-Lin, Shang Xin-Yu, Ni Tao, Yan Hui, Luo Xiaoyan, Zhen Hanliang, Li Zhong, Deng Wei-Ping. Diastereo- and Enantioselective Synthesis of Bisbenzannulated Spiroketals and Spiroaminals by Ir/Ag/Acid Ternary Catalysis. Angew. Chem. Int. Ed., 202261, e202210207.


114. Yang Wu-Lin, Shang Xin-Yu, Luo Xiaoyan, Deng Wei-Ping. Enantioselective Synthesis of Spiroketals and Spiroaminals via Gold and Iridium Sequential Catalysis. Angew. Chem. Int. Ed., 202261, e202203661.


113. Zhang Jian, Yang Wu-Lin, Zheng Hanliang, Wang Yi, Deng Wei-PingRegio- and Enantioselective γ-Allylic Alkylation of In-Situ-Generated Free Dienolates via Scandium/Iridium Dual Catalysis. Angew. Chem. Int. Ed., 202261, e202117079.


112. Zeng Daming, Ma Yinhao, Deng Wei-Ping, Wang Ming, Jiang Xuefeng. Divergent sulfur(VI) fluoride exchange linkage of sulfonimidoyl fluorides and alkynes. Nature Synthesis, 2022, DOI: 10.1038/s44160-022-00060-1.


111. Yang Wu-Lin, Shen Jia-Huan, Zhao Zeng-Hui, Wang Zhongao, Deng Wei-Ping. Stereoselective synthesis of functionalized azepines via gold and palladium relay catalysis. Org. Chem. Front.2022, DOI: 10.1039/d2qo00646d.


110. He Fu-Sheng, Bao Ping, Tang Zhimei, Yu Feiyan, Deng Wei-Ping, Jie Wu. Photoredox-Catalyzed α-Sulfonylation of Ketones from Sulfur Dioxide and Thianthrenium Salts. Org. Lett., 202224, 2955-2960.


2021

109. Yang Wu-Lin, Wang Yuan-Lin, Li Wen, Gu Bu-Ming, Wang Si-Wen, Luo Xiaoyan, Tian Bo-Xue, Deng Wei-Ping. Diastereo- and Enantioselective Synthesis of Eight-Membered Heterocycles via an Allylation/Ring Expansion Sequence Enabled by Multiple Catalysis. ACS Catal.202111, 12557-12654.


108. Zhang Jian, Gao Yan-Shan, Gu Bu-Ming, Yang Wu-Lin, Tian Bo-Xue, Deng Wei-Ping. Cooperative N-heterocyclic Carbene and Iridium Catalysis Enables Stereoselective and Regiodivergent [3+2] and [3+3] Annulation Reactions. ACS Catal.202111, 3810-3821.


107. Zhang Jian, Deng Wei-Ping. Stereodivergent Synthesis of Chiral Spirocycles via Dual-Metal Catalysis. Chin. J. Org. Chem., 202141, 4832-4833.


106. He Fu-Sheng, Bao Ping, Yu Feiyan, Zeng Ling-Hui, Deng Wei-Ping, Wu Jie. Copper-Catalyzed Regioselective 1,4-Selenosulfonylation of 1,3-Enynes to Access Tetrasubstituted Allenes from Sulfur Dioxide. Org. Lett., 202123, 7472-7476.


105.  Zhao  Jianhong,   Zheng Xing, Gao   Yan-Shan , Mao Jia, Wu Shu-Xiao,  Yan Wu-Lin , Luo Xiaoyan,  Deng Wei-Ping Organocatalytic Enantioselective [8+4] Cycloadditions of Isobenzofulvenes for the Construction of Bicyclo[4.2.1]- nonanes. Chin. J. Chem. 2021 39 , 3219-3224.


104.  Shen Jia-Huan, Tian Fei, Yang Wu-Lin, Deng Wei-Ping. Synergistic copper and chiral Lewis base catalysis for the asymmetric synthesis of pyrrolo[1,2-a]indoles. Chin. J. Chem.202139, 3292-3296.


103. Bao Ping, Yu Feiyan, He Fu-Sheng, Tang Zhimei, Deng Wei-Ping and Wu Jie. Visible-light-induced remote C(sp3)–H sulfonylvinylation: assembly of cyanoalkylated vinyl sulfones. Org. Chem. Front.20218, 4820-4825.


102. Yang Wu-Lin, Liu Tian-Tian, Ni Tao, Zhu Bin, Luo Xiaoyan, Deng Wei-Ping. Iridium-Catalyzed Asymmetric Cascade Allylation/Pictet-Spengler Cyclization Reaction for the Enantioselective Synthesis of 1,3,4-Trisubstituted Tetrahydro-isoquinolines. Org. Lett., 202123, 2790-2796.


101. Yang Wu-Lin, Ni Tao, Deng Wei-Ping. Iridium-Catalyzed Diastereo- and Enantioselective [4+3] Cycloaddition of 4-Indolyl Allylic Alcohols with Azomethine Ylides. Org. Lett., 202123, 588-594.


100. Liu Yang-Zi, Wang Zhongao, Huang Zesheng, Yang Wu-Lin, Deng Wei-Ping. Sulfone as a Transient Activating Group in the Palladium-Catalyzed Asymmetric [4+3] Cycloaddition of Trimethylenemethane Enabling the Enantioselective Synthesis of Fused Azepines. Org. Lett., 202123, 948-952.


99. Xu Hui, Han Teng, Luo Xiaoyan, Deng Wei-Ping. The construction of 3-azabicyclo[3.1.0]hexane backbone by the reaction of allenes with allylamines via tandem aza-Michael addition and Copper-mediated oxidative carbanion cyclization. Chin. J. Chem.202139, 666-670.


98. Tian Fei, Yang Wu-Lin, Ni Tao, Zhang Jian ,   Deng Wei-Ping .   Catalytic  a symmetric dipolar cycloadditions of indolyl delocalized metal-allyl species for the enantioselective synthesis of cyclopenta[b]indoles and pyrrolo[1,2- a ] indoles. SciChin. Chem., 2021, 64(1), 34-40.


97. Gu Boqi, Wu Shuxiao, Xu Hui, Yang Wulin, Liu Zhixiang, Deng Wei-Ping. Organocatalytic asymmetric [3+3] annulation of isatin N,N'-cyclic azomethine imines with enals: Efficient approach to functionalized spiro N-heterocyclic oxindoles. Chin. Chem. Lett., 202132, 672-675.


2020 

96. Ding Xiang-Feng, Deng Wei-Ping. Asymmetric Inverse-Electron-Demand Diels-Alder Reaction of 2-Pyrones. Chin. J. Org. Chem., 202040, 3262-3278.


95. Deng Hua, Liu Tian-Tian, Ding Zheng-Dong, Yang Wu-Lin, Luo Xiaoyan, Deng Wei-PingKinetic resolution of 2H-azirines via Cu(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylidesOrg. Chem. Front.20207(20), 3247-3252.


94. Ye Chao, Yang Wu-Lin, Zhai Yufei, Deng Hua, Luo Xiaoyan, Kai Guoyin, Deng Wei-Ping. Copper(I)-Catalyzed Asymmetric [3+3] Annulation Involving Aziridines to Construct Tetrahydro-β-carbolines. Org. Chem. Front.20207(21), 3393-3398.


93. Yang Wu-Lin, Huang Zesheng, Liu Yang-Zi, Yu Xingxin, Deng Wei-Ping. Highly Regio-, Diastereo-, and Enantioselective Assembly of Azepino[2,3-b]indoles via Palladium-Catalyzed [4+3] Cycloaddition. Chin. J. Chem.202038(12), 1571-1574.


92. Tian Fei, Zhang Jian, Yang Wu-Lin, Deng Wei-Ping. Progress in Iridium-Catalyzed Asymmetric Allylic Substitution Reactions via Synergetic Catalysis. Chin. J. Org. Chem., 202040, 3262-3278.


91. Zhang Jian, Ni Tao, Yang Wu-Lin, Deng Wei-Ping. Catalytic Asymmetric [3+2] Annulation via Indolyl Copper-Allenyliende Intermediates: Diastereo- and Enantioselective Assembly of Pyrrolo[1,2-a]indoles. Org. Lett., 202022, 4547-4552.


90. Yang Wu-Lin, Li Wen, Yang Zhong-Tao, Deng Wei-Ping. Organocatalytic Regiodivergent Ring Expansion of Cyclobutanones for the Enantioselective Synthesis of Azepino[1,2-a]indoles and Cyclohepta[b]indoles. Org. Lett. 202022, 4026-4032.


89. Zheng Xing, Sun Hao, Yang Wu-Lin, Deng Wei-Ping. Elaboration of phosphoramidite ligands enabling palladium-catalyzed diastereo- and enantioselective all carbon [4+3] cycloaddition. Sci. Chin. Chem.202063, 911-916.


88. Zou Xue-Jie, Yang Wu-Lin, Zhu Jing-Yan, Deng Wei-Ping. Catalytic Enantioselective Formal Synthesis of MDM2 Antagonist RG7388 and Its Analogue. Chin. J. Chem.202038(5), 435-438.


87. Liu Yang-Zi, Wang Zhongao, Huang Zesheng, Zheng Xing, Yang Wu-Lin, and Deng Wei-Ping. Palladium-Catalyzed Asymmetric [4+3] Cyclization of Trimethylenemethane: Regio-, Diastereo-, and Enantioselective Construction of Benzofuro[3,2-b]azepine Skeletons. Angew. Chem. Int. Ed., 202059, 1238-1242.


86. Zou Xuejie, Liu Yangzi, Shang Shaojing, Yang Wulin, Deng Wei-Ping. Diastereoselective Synthesis of Functionalized Tetrahydro-γ-Carbolines via a [3+3] Cycloaddition of 2,2'-Diester Aziridines with β-(Indol-2-yl)-α,β-unsaturated Ketones. Chin. Chem. Lett., 202031, 1293-1296.


85. Yang Wulin, Wang Hao, Pan Zirong, Li Zhong, Deng Weiping.  Asymmetric synthesis of pyrrolo[1,2- a ]indoles  via  organocatalytic [3+2] annulation of substituted 2-vinylindoles with azlactones. Chin. Chem. Lett., 202031, 721-724.

 

2019 

84. Leng Jiaying, Xu Hui, Meng Jiang, Luo Xiaoyan, Deng Wei-Ping. Transition-metal-free synthesis of polysubstituted pyrrole derivatives via [4+1] annulation of beta-keto acids (C1 synthon) and α,β-unsaturated imines. Tetrahedron201975, 130709.


83. Zhu Jinbin, Huang Linwei, Dong Wei, Li Naikai, Yu Xingxin, Deng Wei-Ping, Tang Wenjun. Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to N-Unprotected Ketimines: Efficient Synthesis of Cipargamin. Angew. Chem. Int. Ed.2019, 58, 16119-16123.


82. Chen Long, Yang Wu-Lin, Shen Jia-Huan, Deng Wei-Ping. Nickel(II)-Catalyzed Diastereo- and Enantioselective Michael/Hemiacetalization Cascade Reaction of α-Ketoesters with 2-(2-Nitrovinyl)phenols. Adv. Synth. Catal., 2019361(19), 4611-4622.


81. Mao Jia, Zhang Hao, Ding Xiang-Feng, Luo Xiaoyan, Deng Wei-Ping. Synergistic Catalysis for Asymmetric [3+2] Cycloadditions of 2-Indolylmethanols with α,β-Unsaturated Aldehydes. J. Org. Chem. 201984(17), 11186-11194.


80. Wu Shu-Xiao, Gu Bo-Qi, Xu Hui, Zheng Xing, Luo Xiaoyan, Deng Wei-Ping. Organocatalytic Asymmetric Inverse-Electron-Demand Diels-Alder Reaction of Pyrrolidone-Dienes with Enals. Adv. Synth. Catal., 2019361(18), 4302-4313.


79.  Deng Hua, Jia Renmeng, Yang Wu-Lin, Yu Xingxin,  Deng Wei-Ping . Ligand-Controlled Switch in Diastereoselectivities Catalytic Asymmetric Construction of Spirocyclic Pyrrolidine-azetidine/oxe(thie)tane Derivatives. Chem. Commun., 201955, 7346-7349.


78. Ding Xiang-Feng, Yang Wu-Lin, Mao Jia, Cao Cong-Xian, Deng Wei-Ping. Enantioselective Construction of Dihydropyrido[1,2-a]indoles via Organocatalytic Arylmethylation of 2-Enals with Inert Aryl Methane Nucleophiles. Org. Lett., 201921, 5514-5518.


77. Jin Jing-Hai, Zhao Jianhong, Yang Wu-Lin, Deng Wei-PingAsymmetric synthesis of spirooxindole β-lactams via isothiourea-catalyzed Mannich/lactamization reaction of aryl acetic acids with isatin-derived ketimines. Adv. Synth. Catal., 2019361(7), 1592-1596.


76. Yang Zhong-Tao, Zhao Jianhong, Yang Wu-Lin, Deng Wei-Ping. Enantioselective Construction of CF3-Containing Spirooxindole γ-Lactones via Organocatalytic Asymmetric Michael/Lactonization. Org. Lett., 201921, 1015-1020.


75. Yang Wu-Lin, Sun Zhong-Tao, Sun Hao, Deng Wei-Ping. Nickel(II)-Catalyzed Diastereo- and Enantioselective [3+2] Cycloaddition of α-Ketoesters with 2-Nitrovinylindoles and 2-Nitrovinylpyrroles. Chin. J. Chem., 201937, 216-220.


74. Yang Wu-Lin, Sun Zhong-Tao, Zhang Jian, Li Zhong, Deng Wei-Ping. Enantioselective synthesis of 3-amino-hydrobenzofuran-2,5-diones via Cu(I)-catalyzed intramolecular conjugate addition of imino esters. Org. Chem. Front., 20196, 579-583.

 

2018 

73. Gu Bo-Qi, Yang Wu-Lin, Wu Shu-Xiao, Wang Yan-Bing, Deng Wei-Ping. Organocatalytic asymmetric synthesis of tetrahydrocarbazoles via an inverse-electron demand Diels–Alder reaction of 2,3-indole-dienes with enals. Org. Chem. Front., 20185, 3430-3434.


72. Leng Jiaying, Meng Jiang, Luo Xiaoyan, Deng Wei-Ping. Formal [4+1] Cycloaddition Strategy for the Synthesis of Dihydrobenzofurans via Michael Addition of 2-(2-nitrovinyl)-phenols and Malonate Esters (C1 Synthon) and Subsequent Iodine-catalyzed Oxidative Annulation. Tetrahedron201874, 6993-6999.


71. Jin Jing-Hai, Li Xiang-Yu, Luo Xiaoyan, Deng Wei-Ping. Enantioselective synthesis of indolo[2,3-b]-dihydrothiopyranones via [3+3] cycloaddition of chiral α,β-unsaturated acylammonium salts. Tetrahedron201874, 6804-6808.


70. Ding Xiang-Feng, Su Ruo-Heng, Yang Wu-Lin, Deng Wei-Ping. Organocatalytic Asymmetric Formal Aza-[3+3] Cycloadditions of 3-Aminobenzofuran with α,β-Unsaturated Aldehydes. Adv. Synth. Catal., 2018360, 4168-4177.


69. Deng Hua, Yang Wu-Lin, Tian Fei, Tang Wenjun, Deng Wei-Ping. Asymmetric Construction of 3-Azabicyclo[3.1.0]hexane Skeleton with Five Contiguous Stereogenic Centers by Cu-Catalyzed 1,3-Dipolar Cycloaddition of Trisubstituted Cyclopropenes. Org. Lett., 201820, 4121-4125. 


68. Tian Fei, He Fu-Sheng, Deng Hua, Yang Wu-Lin, Deng Wei-Ping. β-Silyl Acrylates in Asymmetric [3+2] Cycloadditions Affording Pyrrolidine Azasugar Derivatives. Org. Lett., 201820, 3838-3842. 


67. Zheng Xing, Yang Wu-Lin, Liu Yang-Zi, Wu Shu-Xiao, Deng Wei-Ping. Enantioselective Synthesis of Tropanes via [3+3] Annulation of Cyclic Azomethine Ylides with Substituted 2-Vinylindoles and 2-Vinylpyrroles. Adv. Synth. Catal., 2018360(15), 2843-2853. 


66. Liu Yang-Zi, Shang Shao-Jing, Zhu Jing-Yan, Yang Wu-Lin, Deng Wei-Ping. Regioselective and Stereoselective [3+3] Annulation of Ketones Derived Azomethine Ylides with 2-Indolylethylenes: Direct Access to Highly Substituted Tetrahydro-γ-Carbolines. Adv. Synth. Catal., 2018360(11), 2191-2203.


65. Zhu Jing-Yan, Yang Wu-Lin, Liu Yang-Zi, Shang Shao-Jing, Deng Wei-Ping. Copper(I)-catalyzed Asymmetric Mannich Reaction of Glycine Schiff Bases with Isatin-derived Ketimines: Enantioselective Synthesis of 3-Substituted 3-Aminooxindoles. Org. Chem. Front., 20185, 70-74.


64. Jin Jing-Hai, Wang Hao, Yang Zhong-Tao, Yang Wu-Lin, Tang Wenjun, Deng Wei-Ping. Asymmetric Synthesis of 3,4-Dihydroquinolin-2-ones via a Stereoselective Palladium-Catalyzed Decarboxylative [4+2] Cycloaddition. Org. Lett., 201820, 104-107. 


63. Han Teng, Wang Yu, Li Hong-Liang, Luo Xiaoyan, Deng Wei-Ping. Synthesis of Polysubstituted 3-Aminothiophenes from Thioamides and Allenes via Tandem Thio-Michael Addition/Oxidative Annulation and 1,2-Sulfur Migration. J. Org. Chem., 201883, 1538-1542.


62. Jia Renmeng, Meng Jiang, Leng Jiaying, Yu Xingxin, Deng Wei-Ping. Rhodium (II)-Catalyzed Reaction of 1-Tosyl-1,2,3-triazoles with Morita–Baylis–Hillman adducts: Synthesis of 3,4-Fused Pyrroles. Chem. Asian J., 201813, 2360-2364.


61. Yang Zhong-Tao, Yang Wu-Lin, Chen Long, Sun Hao, Deng Wei-Ping. Organocatalytic Enantioselective aza-Friedel-Crafts Reactions of Pyrazolinone Ketimines with Hydroxyindoles and Electron-Rich Phenols. Adv. Synth. Catal., 2018360(10), 2049-2054.


60. Wen Min, Sun Pei-Pei, Luo Xiaoyan, Deng Wei-Ping. Cu(II)-catalyzed one-pot synthesis of fully substituted dihydrothiophenes and thiophenes from thioamides and enynones. Tetrahedron201874(31), 4168-4173.

 

2017 

59. He Fu-Sheng, Li Cong-Shan, Deng Hua, Zheng Xing, Yang Zhong-Tao, Deng Wei-Ping. The facile and stereoselective synthesis of pyrrolidine β-amino acids via copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition. Org. Chem. Front., 20174, 52-56.


58. Liu Yang-Zi, Shang Shao-Jing, Yang Wu-Lin, Luo Xiaoyan, Deng Wei-Ping. Stereoselective Synthesis of Pyrrolidines Containing a 3-Fluoro Quaternary Stereocenter via Copper(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition. J. Org. Chem., 201782(20), 11141-11149.


57. Jin Jing-Hai, Xu Qin-Chang, Deng Wei-Ping. DMAP-catalyzed [4+2] cycloaddition of α,β-unsaturated carboxylic acids with ketones for the synthesis of α,β-unsaturated δ-lactones. Chin. J. Chem., 201735, 397-400.


56. Meng Jiang, Wen Min, Zhang Shiwei, Pan Peiwen, Yu Xingxin, Deng Wei-Ping. Unexpected O−H Insertion of Rhodium-Azavinylcarbenes with N-Acylhydrazones: Divergent Synthesis of 3,6-Disubstituted and 3,5,6-Trisubstituted-1,2,4-Triazines. J. Org. Chem., 201782, 1676−1687. 


55. Jin Jing-Hai, Li Xiang-Yu, Luo Xiaoyan, Fossey John S., Deng Wei-Ping. Asymmetric Synthesis of cis-3,4-Dihydrocoumarins via [4+2] Cycloadditions Catalyzed by Amidine Derivatives. J. Org. Chem., 201782, 5424-5432.


54. Meng Jiang, Jia Renmeng, Leng Jiaying, Wen Min, Yu Xingxin, Deng Wei-Ping. Carbon−Carbon Bond Formation by Reaction of Rhodium Azavinylcarbenes with Secondary Amides: Access to Indigo Analogues from Isatins. Org. Lett., 201719, 4520-4523.


53. Deng Hua, He Fu-Sheng, Li, Cong-Shan, Deng Wei-Ping. Enantioselective Construction of Tricyclic Pyrrolidine-Fused Benzo[b]thiophene 1,1-Dioxides Derivatives via Copper(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition. Org. Chem. Front., 20174, 2343-2347.


52. Su Ruo-Heng, Ding Xiang-Feng, Wu Shu-Xiao, Zhao Jian-Hong, Deng Wei-Ping. Secondary Amine-catalyzed Asymmetric Formal Aza [3+3] Cycloaddition to Construct Enantioenriched Piperidines Derivatives. Tetrahedron, 201773(41), 6031-6038.


 

2016

51. He Fu-Sheng, Jin Jing-Hai, Yang Zhong-Tao, Yu Xingxin, Fossey John S., Deng Wei-Ping. Direct Asymmetric Synthesis of β-Bis-Aryl-α-Amino Acid Esters via Enantioselective Copper-Catalyzed Addition of p-Quinone Methides. ACS Catalysis, 20166(2), 652-656. 


50. Huang Linwei, Zhu Jinbin, Jiao Guangjun, Wang Zheng, Yu Xingxin, Deng Wei-Ping, Tang Wenjun. Highly Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to Simple Aryl Ketones: Efficient Synthesis of Escitalopram. Angew. Chem. Int. Ed., 201655(14), 4527-4531. 


49. Li Hong-Liang, Wang Yu, Sun Pei-Pei, Luo Xiaoyan, Shen Zhenlu, Deng Wei-Ping. α,β-Double electrophilic addition of allene-1,3-dicarboxylic esters for the construction of polysubstituted furans via KI/TBHP promoted oxidative annulation. Chem. Eur. J., 201622, 9348-9355.


48. Yang Wu-Lin, Li Chun-Yan, Qin Wen-Jing, Tang Fei-Fei, Yu Xingxin, Deng Wei-Ping. Cu(I)-Catalyzed Chemoselective and Stereoselective [3+3] Cycloaddition of Azomethine Ylides with 2-Indolylnitroethylenes: Facile Access to Highly Substituted Tetrahydro-γ-Carbolines. ACS Catalysis, 20166, 5685-5690. 


47. Wang Yu, Jiang Chen-Min, Li Hong-Liang, He Fu-Sheng, Luo Xiaoyan, Deng Wei-Ping. Regioselective Iodine-catalyzed Construction of Polysubstituted Pyrroles from Allenes and Enamines. J. Org. Chem., 201681, 8653-8658.


46. Gu Bo-Qi, Zhang Hao, Su Ruo-Heng, Deng Wei-Ping. Organocatalytic asymmetric synthesis of dihydrocarbazoles via a formal [4+2] cycloaddition of in situ generated o-quinodimethanes with enals. Tetrahedron201672, 6595-6602.


45. Zhu Mingyu, Deng Weiping. An-PIQ Catalyzed Kinetic Resolution of β-Iodo Morita–Baylis–Hillman Adducts. Chin. J. Org. Chem., 201636 (10): 2397-2406.


44. Li Hongliang, Wang Zhenglin, Deng Weiping. Cu(I)-Catalyzed Intramolecular Cyclization of Ortho-halogenated Phenylthioacetamides for the Synthesis of 2-Amino Benzo[b]thiophenes. Chin. J. Org. Chem., 201636 (10): 2419-2425.


43. Meng Jiang, Ding Xiangfeng, Yu Xingxin, Deng Wei-Ping. Synthesis of 2,5-epoxy-1,4-benzoxazepines via rhodium(II)-catalyzed reaction of 1-tosyl-1,2,3- triazoles and salicylaldehydes. Tetrahedron, 201672, 176-183.

       


2015

42. Jiang Shan-Shan, Xu Qin-Chang, Zhu Ming-Yu, Yu Xingxin, Deng Wei-Ping. Kinetic Resolution of α-Methylene-β-hydroxy Esters Catalyzed by Acyl Transfer Catalyst An-PIQ. J. Org. Chem.201580, 3159-3169.


41. Jiang Shan-Shan, Gu Bo-Qi, Zhu Ming-Yu, Yu Xingxin, Deng Wei-Ping. Nonenzymatic kinetic resolution of α-aryl substituted allylic alcohols catalyzed by acyl transfer catalyst Np-PIQ. Tetrahedron201571, 1187-1191.


40. Qin Wen-Jing, Li Yi, Yu Xingxin, Deng Wei-Ping. TBAI/TBHP catalyzed direct N-acylation of sulfoximines with aldehydes. Tetrahedron201571, 1182-1186.


39. Li Hong-Liang, An Xing-Lan, Ge Li-Shi, Luo Xiaoyan, Deng Wei-Ping. Catalyitc α-Hydroxylation of Ketones under CuBr2 or HBr/DMSO Systems. Tetrahedron, 201571, 3247-3252.


38. Meng Jiang, Wu Di, Shi Ying, Yu Xingxin, Deng Wei-Ping. Construction of 1H-pyrrol-2-ylphosphonates via [3+2] cycloaddition of phosphate azomethine ylides with ynones. Tetrahedron201571, 1074-1079.


37. Luo Xiaoyan, Ge Li-Shi, An Xing-Lan, Jin Jing-Hai, Wang Yu, Sun Pei-Pei, Deng Wei-Ping. Regioselective Metal-Free One-pot Synthesis of Functionalized 2-Aminothiophene Derivatives. J. Org. Chem., 201580, 4611-4617.


36. Yang Wu-Lin, Liu Yang-Zhi, Luo Shuai, Yu Xingxin, Fossey John S., Deng Wei-Ping. Copper-catalyzed asymmetric construction of dispiropyrrolidine skeleton via 1,3-dipolarcycloaddition of azomethine ylides with α-alkylidene. Chem. Commun., 201551, 9212-9215. 


35. Wang Zheng, Yu Xingxin, Tian Bo-Xue, Payne Daniel T., Yang Wu-Lin, Liu Yang-Zi, Fossey John S., Deng Wei-Ping. Chiral N,O-Ligand/Cu(OAc)2 Catalyzed Asymmetric Construction of 4-Aminopyrrolidine Derivatives via 1,3-Dipolar Cycloaddition of Azomethine Ylides with α-phthalimidoacrylates. Chem. Eur. J., 201521, 10457-10465.


34. Tang Fei-Fei, Yang Wu-Lin, Yu Xingxin, Deng Wei-Ping. Cu(OAc)2/FOXAP complex catalyzed construction of 2,5-dihydropyrrole derivatives via asymmetric 1,3-dipolar cycloaddition of azomethine ylides with ethynyl ketones. Catal. Sci. Technol., 20155, 3568-3575.


33. Yang Wu-Lin, Tang Fei-Fei, He Fu-Sheng, Li Chun-Yan, Yu Xingxin, Deng Wei-Ping. Asymmetric construction of spirocyclic pyrrolidine-thia(oxa)zolidinediones via N,O-ligand/Cu(I) catalyzed 1,3-dipolar cycloaddition of azomethine ylides with 5-alkylidene thia(oxa)zolidine-2,4-diones. Org. Lett., 201517, 4822-4825.


 32. He Fu-Sheng, Zhu Han, Wang Zheng, Gao Ming, Yu Xingxin, Deng Wei-Ping. Asymmetric Construction of 3,4-Diamino Pyrrolidines via Chiral N,O-Ligand/Cu(I) Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with β-Phthalimidonitroethene. Org. Lett., 201517, 4988-4991. 


31.  Li Chun-Yan, Yang Wu-Lin, Luo Xiaoyan, Deng Wei-Ping. Diastereodivergent asymmetric Michael addition of cyclic azomethine ylides to nitroalkenes: direct approach for the synthesis of 1,7-diazaspiro[4.4]nonane diastereoisomers. Chem. Eur. J., 201521, 19048-19057.

 

2014 

30. Wang Zheng, Ye Jinjin, Wu Rui, Liu Yang-Zi, Fossey John S., Cheng Jiagao, Deng Wei-Ping. Bi-Aryl Rotation in Phenyl-dihydroimidazoquinoline Catalysts for Kinetic Resolution of Arylalkyl Carbinols. Catal. Sci. Technol., 2014(7), 1909-1913.


29. Wang Zheng-Lin, Li Hong-Liang, Ge Li-Shi, An Xing-Lan, Zhang Zi-Gang, Luo Xiaoyan, Fossey John S., Deng Wei-Ping. DDQ-Mediated Oxidative Coupling: An Approach to 2,3-Dicyanofuran (Thiophene). J. Org. Chem., 201479, 1156-1165. 


28. Wang Zheng-Lin, An Xing-Lan, Ge Li-Shi, Jin Jing-Hai, Luo Xiaoyan, Deng Wei-Ping. DDQ-mediated oxidation of sp3 C-H bond for the direct synthesis of vicinal tricarbonyl compounds. Tetrahedron, 2014, 70, 3788-3792.


27. Li Yi, Cao Li, Luo Xiaoyan, Deng Wei-Ping. The synthesis of 1, 2-diarylindenes via DDQ-mediated dehydrogenative intramolecular cyclization. Tetrahedron, 2014, 70, 5974-5979.


26. Jiang Shanshan, Hu Bin, Yu Xingxin, Deng WeiPing. Fc-PIP Catalyzed Asymmetric Synthesis of cis-2,3-Dihydrobenzofurans. Chin. J. Chem., 201432, 694-698.


25. Ge Li-Shi, Wang Zheng-Lin, An Xing-Lan, Luo Xiaoyan, Deng Wei-Ping. Direct Synthesis of Polysubstituted 2-Aminothiophenes through Cu(II)-Catalyzed Addition/Oxidative Cyclization of Alkynoates with Thioamides. Org. Biomol. Chem., 201412(42), 8473-8479. 


24. Luo Xiaoyan, Wang Zheng-Lin, Jin Jing-Hai, An Xing-Lan, Shen Zhenlu, Deng Wei-Ping. Copper-catalyzed α-aminoxylation of 1,3-dicarbonyl compounds with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) via an aerobic oxidative sp3 C-H bond activation. Tetrahedron, 2014, 70, 8226-8230.


2013 

23. Wang Wei-Liang, Feng Yu-Lan, Gao Wen-Qiang, Luo Xiaoyan, Deng Wei-Ping. A highly efficient BFEt2O-catalysed intramolecular [3+2] cycloaddition for the synthesis of 3,4-dihydrobenzopyrano[3,4-c]pyrazoles. RSC Adv.20133, 1687-1690.


22. Wang Zheng, Shi Ying, Luo Xiaoyan, Han De-Man, Deng Wei-Ping. Direct synthesis of pyrroles via 1,3-dipolar cycloaddition of azomethine ylides with ynones. New J. Chem.2013, 37, 1742-1745. 


21. Wang Zheng, Luo Shuai, Zhang Shoude, Yang Wu-Lin, Liu Yang-Zi, Li Honglin, Luo Xiaoyan, Deng Wei-Ping. Catalytic Asymmetric Construction of Quaternary a-Amino Acid-Containing Pyrrolidines via 1,3-Dipolar Cycloaddition of Azomethine Ylides to a-Aminoacrylates. Chem. Eur. J.201319, 6739-6745.


20. An Na, Tian Bo-Xue, Pi Hong-Jun, Eriksson Leif A., Deng Wei-Ping. Mechanistic Insight into Self-propagation of Organo-mediated Beckmann Rearrangement: A Combined Experimental and Computational Study. J. Org. Chem., 201378, 4297-4302.


19. Xu Su-Ying, Hu Bin, Flower Stephen E., Jiang Yun-Bao, Fossey John S., Deng Wei-Ping, James Tony D. Colorimetric enantioselective recognition of chiral secondary alcohols via hydrogen bonding to a chiral metallocene containing chemosensor. Chem. Commun., 201349, 8314-8316.

           

18. Jin Hui, Liang Lei, Liu Lifeng, Deng Weiping, Liu Jianwen. HDAC Inhibitor DWP0016 Activates p53 Transcription and Acetylation to Inhibit Cell Growth in U251 Glioblastoma Cells. J. Cell. Biochem., 2013114, 1498-1509.

 

2012 

17. Liu Hua, Cao Li, Sun Jia, Fossey John S., Deng Wei-Ping. Iron-catalysed Tandem Cross-dehydrogenative Coupling (CDC) of Terminal Allylic C(sp3) to Styrene and Benzoannulation in the Synthesis of Polysubstituted Naphthalenes. Chem. Commun., 2012, 48 (21), 2674-2676.


16. Shi Yu-Hua, Wang Zheng, Shi Ying, Deng Wei-Ping. Facile and Highly Diastereoselective Synthesis of 3-Aminooxindoles via AgOAc-Catalyzed Vinylogous Mannich Reaction. Tetrahedron, 2012, 68, 3649-3653.


15. Li Yi, Du Wenting, Deng Wei-Ping. NHCs-mediated benzoates formation directly from aromatic aldehydes and halides. Tetrahedron, 201268, 3611-3615.


14. Wang Zheng, Han De-Man, Jia Wen-Ping, Zhou Qi-Zhong, Deng Wei-Ping. Reaction-Based Fluorescent Probe for Selective Discrimination of Thiophenols over Aliphaticthiols and Its Application in Water Samples. Anal. Chem., 201284, 4915 -4920.


13. Li Yi, Cao Li, Luo Xiaoyan, Deng Wei-Ping. Highly Substituted Cyclopentenes Formation via a Stereoselective Tandem CDC Reaction and Cyclization. Chin. J. Chem. 201230, 2834-2838.


12. Hu Bin, Meng Meng, Jiang Shanshan, Deng Wei-Ping. Kinetic Resolution of Aryl Alkenylcarbinols Catalyzed by Fc-PIP. Chin. J. Chem., 201230, 1289-1294.

 

2011 

11. Wang Ming, Shi Yu-Hua, Luo Jun-Fei, Du Wenting, Shi Xiao-Xin, Fossey John S., Deng Wei-Ping. Novel N,O-Cu(OAc)2 complex catalysed diastereo- and enantioselective 1,4-addition of glycine derivatives to alkylidene malonates. Catal. Sci. Technol., 20111(1), 100-103.


10. Fan Wen-Yuan, Wang Zheng-Lin, Li Hong-Chang, Fossey John S., Deng Wei-Ping. A straightforward and efficient synthetic access to biologically active marine sesterterpenoids, sesterstatins 4 and 5. Chem. Commun., 201147, 2961-2963.


9. Wang Ming, Wang Zheng, Shi Yu-Hua, Shi Xiao-Xin, Fossey John S., Deng Wei-Ping. A Remarkable N,O-ligand/Cu(OAc)2 Derived Chiral Complex Catalysed exo-Selective and Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides with Alkylidene Malonates. Angew. Chem. Int. Ed., 2011, 50, 4897-4900. 


8. Liu Li-Feng, An Na, Pi Hong-Jun, Ying Jun, Du Wenting, Deng Wei-Ping. Facile and odorless one-pot process for the synthesis of N-substituted thioamides via TsCl mediated BR of ketoximes. Synlett., 20117, 979-981.


7. Fan Wen-Yuan, Wang Zheng-Lin, Zhang Zi-Gang, Li Hong-Chang, Deng Wei-Ping. Stereoselective synthesis of marine sesterterpenes, 16-deacetoxy-scalarafuran, (+)-scalarolide and their analogs. Tetrahedron, 201167, 5596-5603.


6. Wang Zheng-Lin, Liu Yang, Zhang Zi-Gang, Li Hong-Chang, Deng Wei-Ping. Concise stereoselective synthesis of marine sesterterpene, 16-deacetoxy-12-epi- scalarafuran acetate and its 14-epimer via intramolecular Diels-Alder addition. Tetrahedron, 2011, 67, 6939-6943.


5. Hu Bin, Meng Meng, Fossey John S., Mo Weimin, Hu Xinquan, Deng Wei-Ping. Optically pure bulky (hetero)arylalkyl carbinols via kinetic resolution. Chem. Commun., 2011, 47, 10632-10634.


4. Shi Yu-Hua, Wang Zheng, Hu Bin, Wang Ming, Fossey John S., Deng Wei-Ping. A Ferrocenyl-DHIPOH/ Cu(OAc)2 Complex for Diastereo- and Enantioselective Catalysis of The 1,4-Addition of Glycine Derivatives to Alkylidene Malonates. Org. Lett., 201113, 6010-6013.

 


2010 

3. Hu Bin, Meng Meng, Wang Zheng, Du Wenting, Fossey John S., Hu Xinquan, Deng Wei-Ping. A Highly Selective Ferrocene-Based Planar Chiral PIP (Fc-PIP) Acyl Transfer Catalyst for the Kinetic Resolution of Alcohols. J. Am. Chem. Soc., 2010132, 17041-17044.


2. Lin Lu, Li Yi, Du Wenting, Deng Wei-Ping. The NHCs-Mediated Cross-Coupling of Aromatic Aldehydes with Benzyl Halides: Synthesis of α-Aryl Ketones. Tetrahedron Lett., 2010, 51, 3571-3574.


1. Pi Hong-Jun, Liu Li-Feng, Jiang Shan-Shan, Du Wenting, Deng Wei-Ping. The facile one-pot synthesis of N-imidoylbenzotriazoles via a Beckmann rearrangement of ketoximes. Tetrahedron, 201066, 6097-6100.