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成果及论文

24. Kang, W.;‡ Gao, S.;‡ Bao, J.; Yang, L.; Ma, Y.; Wang, P.; Wang, C.-Y.;* Cui, C.* “Synthetic nicotinamide cofactors as efficient alternatives to NADPH in imine reductase-catalyzed reactions.” Org. Lett.2024, 26, 7817-7821.

23. Ma, Y.;‡ Gao, S.;‡ Wu, J.; Bao, J.; Wang, L.;* and Cui, C.* “Engineered imine reductase catalyzed enantio-divergent synthesis of alkylated amphetamines.” Org. Lett., 2024, 26, 7565-7570.

22. Cui, C.; Yang, L.; Liu, Z.; Shu, X.; Zhang, W.; Gao, Y.; Wang, Y.; Wang, T.; Chen, C.-C.; Guo, R.-R.;* Gao, S.* “Substrate Specificity of a Branch of Aromatic Dioxygenases Determined by Three Distinct Motifs.” Nat. Commun., 2024, 15, 7682.

21. Tang, D.; Ma, Y.; Bao, J.; Gao, S.; Man, S.;* Cui, C.* “Chemoenzymatic total synthesis of rotigotine via IRED-catalyzed reductive amination.” Org. Biomol. Chem.202422, 3843-3847.

Featured as a Front Cover.

20. Yu, Z.-P.; An, C.; Yao, Y.; Yan, J.-Z.; Gao, S.-S.; Gu, Y.-C.; Wang, C.-Y.; Cui, C.* "An unexpected role of EasDaf: catalyzing the conversion of chanoclavine aldehyde to chanoclavine acid." Appl. Microbiol. Biotechnol., 2024, 108, 323.

19. Hu, Y.; Bao, J.; Tang, D.; Gao, S.; Wang, F.; Ding, Z.;* Cui, C.* “Chemoenzymatic total synthesis of (R)-selegiline: an engineered IRED-catalyzed approach.” Molecules, 2024, 29, 1328.

18. Shen, Q.; Yan, J.; Han, Y.; Zhang, Z.; Li, H.; Kong, D.; Shi, J.; Cui, C.;* Zhang, W.* “Peroxygenase-catalyzed kinetic resolution of racemic hydroperoxides.” Angew. Chem. Int. Ed., 2024, 202401590.

17. Li, H.; Duan, P.; * Huang, Y.; Cui, C.; Hollmann, F.; * Ma, Y.; Wang, Y.; Zhang, W. * “Vanadium-Containing Chloroperoxidase-Catalyzed Versatile Valorization of Phenols and Phenolic Acids.” ACS Catal. 2024, 14, 1733-1740.

16. Cui, C.; Dai, M.* "Total Synthesis of UCS1025A via Tandem Carbonylative Stills Cross Coupling and Diels-Alder Reaction". Chin. J. Chem. 2023, 41, 3019-3024. (Invited contribution dedicated to the Special Issue of C1 Chemistry). 

15. Zhu, F.;‡ Zhang, J.;‡ Ma, Y.; Yang, L.; Gao, Q.; Gao, S.-S.;* Cui, C.* Semi-rational design of an imine reductase for asymmetric synthesis of alkylated S-4-azepanamines. Org. Biomol. Chem., 2023, 21, 4181-4184.

14. Zhang, J.;‡ Ma, Y.;‡ Zhu, F.;‡ Bao, J.; Gao, S.-S.; Cui, C.* Structure-guide rational design of an imine reductase for enantio-complementary synthesis of pyrrolidinamine. Chem. Sci., 2023, 14, 4265-4272.

Featured as an Outside Cover.

13. Ma, Y.; Yan, J.; Yang, L.; Yao, Y.; Wang, L.;* Gao, S.-S.;* Cui, C.* A Hybrid System for the Overproduction of Complex Ergot Alkaloid Chanoclavine. Front. Bioeng. Biotechnol. 2022, 10, 2386.

12. Li, J.; Qu, G.; Li, X.; Tian, Y.; Cui, C.; Zhang, F.; Zhang, W.; Ma, J.;* Reetz, M.;* Sun, Z.* Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles. Nat. Commun. 2022, 13, 7813.

11. Zhang, J.; Li, X.; Chen, R.; Tan, X.; Liu, X.; Ma, Y.; Zhu, F.; An, C.; Wei, G.; Yao, Y.; Yang, L.; Zhang, P.; Wu, Q.; Sun, Z.; Wang, B.-G.;* Gao, S.-S.;* Cui, C.* Actinomycetes-derived imine reductases with a preference towards bulky amine substrates. Commun. Chem. 2022, 5, 123.

10. Yu, Z.-P.; An, C.; Yao, Y.; Wang, C.-Y.; Sun, Z.; Cui, C.; Liu, L.;* Gao, S-S* A combined strategy for the overproduction of complex ergot alkaloid agroclavine. Synthetic and Systems Biotechnology, 2022, 7, 1126-1132.

9.  Zhang, J.; Liao, D.; Chen, R.; Zhu, F.; Ma, Y.; Gao, L.; Qu, G.; Cui, C.; Sun, Z.;* Lei, X.;* Gao, S.* Tuning Imine Reductase for Asymmetric Synthesis of Azacycloalkylamines by Concise Structure-Guided Engineering. Angew. Chem. Int. Ed., 2022, e202201908. 

8.   Li, H.; Younes, S. H. H.; Chen, S.; Duan, P.;* Cui, C.; Ron Wever, R.; Zhang, W.;* Hollmann, F.;* A chemoenzymatic Hunsdiecker-type decarboxylative bromination of cinnamic acids. ACS Catal., 2022, 12, 4554–4559.

7.   Cui, C.; Dwyer, B. G.; Liu, C.; Abegg, D.; Yin, X.; Hoch, D.; Cai, Z.; Qiu, N.; Liu, J.; Adibekian, A.; Dai, M.* Total synthesis and chemoproteomics connect curcusone diterpenes with oncogenic protein BRAT 1. J. Am. Chem Soc. 2021, 143, 4379-4386. (contributed equally). 

Featured in Purdue News, ScienceDaily, NSF Research News, and others; Highlighted by X-MOL and Synfacts.

6.   Wang, Y.; Cui, C.; Dai, M.* Flow Chemistry-Enabled Divergent and Enantioselective Total Syntheses of Massarinolin A, Purpurolides B, D, E, 2,3-Deoxypurpurolide C, and Structural Revision of Massarinolin A. Angew. Chem. Int. Ed. 2021, 60, 24828-24832. (contributed equally). 

Selected as a Hot Paper; Featured as an Inside Cover; Highlighted by WileyChem.

5.   H Raffa, N.; Won, T. H.; Sukowaty, A.; Candor, K.; Cui, C.; Halder, S.; Dai, M.;* Figueroa, J. A. L.; Schroeder, F. C.; Keller, N. P.* Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper suffiency and exhibit antimicrobial activity. Proc. Natl. Acad. Sci. USA, 2021, 118, e2015224118. 

4.   Cui, C.; Dai, W.-M.* Total synthesis of laingolide B stereoisomers and assignment of absolute configuration. Org. Lett. 2018, 20, 3358-3361. 

3.   Thistlethwaite, I. R. G.; Bull, F. M.; Cui, C.; Walker, P. D.; Gao S.-S.; Wang, L.; Song Z.; Masschelein, J.; Lavigne, R.; Crump, M. P.; Race, P. R.; Simpson, T. J.; and Wills, C. L.* Elucidation of the relative and absolute stereochemistry of the Kalimantacin/batumin antioiotics. Chem. Sci., 2017, 8, 6196-6201. 

2.   Shi, J.; Wu, J.; Cui, C.; Dai, W.-M.* Microwave-Assisted Iintramolecular Ullmann diaryl etherification as the Post-Ugi annulation for generation of dibenz[b,f][1,4]oxazepine scaffold. J. Org. Chem. 2016, 81, 10392-10403. 

1.  Zhang, J.*; Cui, C.; Chen, H.; Liu, J. The completion of esterification of free fatty acids in Zanthoxylum bungeanum seed oil with ethanol. International Journal of Green Energy, 2014, 11, 822-832.