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成果及论文

1  曾雨洁, 陆俊杏 & 李勃. 全国中学生生物学联赛“生物信息学”试题分析. 中小学班主任, 47-51 (2023) [Corresponding author].

2   Xu, Z.-X., Zhu, X.-M., Yin, H., Li, B., Chen, X.-J., Fan, X.-L., Li, N.-Q., Selosse, M.-A., Gao, J.-Y. & Han, J.-J. Symbiosis between Dendrobium catenatum protocorms and Serendipita indica involves the plant hypoxia response pathway. Plant Physiology, kiad198 (2023) 

3   Nie, X., Dan, Q., Xinyi, Z., Hongrui, D., Hao, Y., Li, B. & Guizhao, L. Clustering ensemble in scRNA-seq data analysis: methods, applications and challenges. Computers in Biology and Medicine 159, 106939 (2023) [IF=6.698, Corresponding author].

4   Long, F., Ma, H., Hao, Y., Tian, L., Li, Y., Li, B., Chen, J., Tang, Y., Li, J. & Deng, L. A Novel Exosome-derived Prognostic Signature and Risk Stratification for Breast Cancer Based on Multi-omics and Systematic Biological Heterogeneity. Computational and Structural Biotechnology Journal (2023) 

5   He, H., Duo, H., Hao, Y., Zhang, X., Zhou, X., Zeng, Y., Li, Y. & Li, B. Computational drug repurposing by exploiting large-scale gene expression data: Strategy, methods and applications. Computers in Biology and Medicine 155, 106671 (2023) [IF=6.698, Corresponding author].

6   Tian, L., Long, F., Hao, Y., Li, B., Li, Y., Tang, Y., Li, J., Zhao, Q., Chen, J. & Liu, M. A cancer associated fibroblasts-related six-gene panel for anti-PD-1 therapy in melanoma driven by weighted correlation network analysis and supervised machine learning. Frontiers in Medicine (2022) [accepted].

7   Qin, D., Bo, W., Zheng, X., Hao, Y., Li, B. & Liang, G. DFBP: a comprehensive database of food-derived bioactive peptides. Bioinformatics (2022) [accepted, Corresponding author].

8   Yin, H., Chen, Y., Xiong, Y., Tao, J., Yang, H., Li, B. & Li, S. Robust biomarkers for early diagnosis of germinoma revealed by multi-omics and machine learning approaches. XXXXX (2022) [revised, Corresponding author].

9   Yang, Q., Li, Y., Li, B. & Gong, Y. A Novel Multi-class Classification Model for Schizophrenia, Bipolar Disorder and Healthy Subjects Using Comprehensive Transcriptomic Data. Computers in Biology and Biomedicine (2022) [under review].

10   Yin, H., Tao, J., Peng, Y., Xiong, Y., Li, B., Li, S. & Yang, H. MSPJ: discovering the potential biomarkers in small gene expression dataset via ensemble learning. Computational and Structural Biotechnology Journal (2022) [under review, Corresponding author].

11   李勃, 何昊, 张晓曦, 李映红 & 杨丹. 立足方法学基点 培育生物信息学素养. 生物学杂志 39(1): 127-130 (2022) [CSCD, 第一作者]. 

12   Wang, P., Xu, X., Li, Y., Li, B., Pei, Q., Yu, P., Jing, C. & Lu, M. in IOP Conference Series: Earth and Environmental Science.  032028 (IOP Publishing).

13   李勃 & 朵泓睿. 单细胞RNA测序数据分析方法研究进展. 重庆师范大学学报(自然科学版) 38(05): 129-135+142 (2021) [CSCD, 第一作者].

14 Yin, H., Zheng, X., Tang, X., Zang, Z., Li, B., He, S., Shen, R., Yang, H. & Li, S. Potential biomarkers and lncRNA-mRNA regulatory networks in invasive growth hormone-secreting pituitary adenomas. Journal of endocrinological investigation 44(9): 1947-1959 (2021) [IF=4.256].

15  Yang, Q., Li, B., Chen, S., Tang, J., Li, Y., Li, Y., Zhang, S., Shi, C., Zhang, Y., Mou, M., Xue, W. & Zhu, F. MMEASE: Online meta-analysis of metabolomic data by enhanced metabolite annotation, marker selection and enrichment analysis. Journal of proteomics 232: 104023 (2021) [IF=4.044, Co-first author].

16 Wang, X., Chai, Z., Pan, G., Hao, Y., Li, B., Ye, T., Li, Y., Long, F., Xia, L. & Liu, M. ExoBCD: a comprehensive database for exosomal biomarker discovery in breast cancer. Briefings in bioinformatics 22(3): bbaa088 (2021) [IF=11.622].

17 Bo, W., Chen, L., Qin, D., Geng, S., Li, J., Mei, H., Li, B. & Liang, G. Application of quantitative structure-activity relationship to food-derived peptides: Methods, situations, challenges and prospects. Trends in Food Science & Technology 114: 176-188 (2021) [IF=12.563, Corresponding author].

18 刘杰, 李勃, 陈晓洁 & 陈斌. 埃及伊蚊不同组织的基因共表达模式分析. 昆虫学报 63(10): 1171-1182 (2020).

19 刘杰, 李勃 & 陈斌. 中华按蚊雌、雄蚊转录组比较分析. 重庆师范大学学报(自然科学版) 37(03): 54-59 (2020).

20 李勃, 陶靖心 & 魏晋艺. 短学时情况下生物信息学课程教学改革——以重庆师范大学为例. 西部素质教育 6(05): 183-184 (2020) [第一作者].

21 李勃, 方斌, 陶靖心 & 刘明伟. 秀丽隐杆线虫基因组编码区的碱基分布特征参数研究. 重庆师范大学学报(自然科学版) 37(03): 14-20 (2020) [CSCD, 第一作者].

22 Yang, Q., Li, B., Tang, J., Cui, X., Wang, Y., Li, X., Hu, J., Chen, Y., Xue, W., Lou, Y., Qiu, Y. & Zhu, F. Consistent gene signature of schizophrenia identified by a novel feature selection strategy from comprehensive sets of transcriptomic data. Briefings in bioinformatics 21(3): 1058-1068 (2020) [IF=11.622].

23 Wei, J., Lu, H., Tao, J., Hao, Y., Huang, D. & Li, B. The complete mitogenome of Lasioglossum affine (Hymenoptera: Halictidae) and phylogenetic analysis. Mitochondrial DNA. Part B, Resources 5(3): 3784-3785 (2020) [IF=0.658].

24 Wang, X., Chai, Z., Li, Y., Long, F., Hao, Y., Pan, G., Liu, M. & Li, B. Identification of Potential Biomarkers for Anti-PD-1 Therapy in Melanoma by Weighted Correlation Network Analysis. Genes 11(4) (2020) [IF=4.096, Corresponding author].

25 Tao, J., Hao, Y., Li, X., Yin, H., Nie, X., Zhang, J., Xu, B., Chen, Q. & Li, B. Systematic Identification of Housekeeping Genes Possibly Used as References in Caenorhabditis elegans by Large-Scale Data Integration. Cells 9(3) (2020) [IF=6.600, Corresponding author].

26 Tang, J., Wang, Y., Fu, J., Zhou, Y., Luo, Y., Zhang, Y., Li, B., Yang, Q., Xue, W., Lou, Y., Qiu, Y. & Zhu, F. A critical assessment of the feature selection methods used for biomarker discovery in current metaproteomics studies. Briefings in bioinformatics 21(4): 1378-1390 (2020) [IF=11.622].

27 Tang, J., Fu, J., Wang, Y., Li, B., Li, Y., Yang, Q., Cui, X., Hong, J., Li, X., Chen, Y., Xue, W. & Zhu, F. ANPELA: analysis and performance assessment of the label-free quantification workflow for metaproteomic studies. Briefings in bioinformatics 21(2): 621-636 (2020) [IF=11.622].

28 张莉娟, 尹华春, 李勃 & 陈斌. 10种昆虫过氧化氢酶基因的全基因组鉴定与特征预测. 重庆师范大学学报(自然科学版) 36(03): 36-43+32 (2019).

29 李勃, 倪雅诗 & 陶靖心. “生物信息学”课程在线教学资源库的设计与构建——以重庆师范大学为例. 无线互联科技 16(22): 95-96 (2019) [第一作者].

30 Zuo, X., Li, B., Zhu, C., Yan, Z. W., Li, M., Wang, X. & Zhang, Y. J. Stoichiogenomics reveal oxygen usage bias, key proteins and pathways associated with stomach cancer. Scientific reports 9(1): 11344 (2019) [IF=4.379].

31 Yin, Y., Li, B., Mou, K., Khan, M. T., Kaushik, A. C., Wei, D. & Zhang, Y. J. Stoichioproteomics reveal oxygen usage bias, key proteins and pathways in glioma. BMC medical genomics 12(1): 125 (2019) [IF=3.063, Co-first author].

32 Yang, Q. X., Wang, Y. X., Li, F. C., Zhang, S., Luo, Y. C., Li, Y., Tang, J., Li, B., Chen, Y. Z., Xue, W. W. & Zhu, F. Identification of the gene signature reflecting schizophrenia's etiology by constructing artificial intelligence-based method of enhanced reproducibility. CNS neuroscience & therapeutics 25(9): 1054-1063 (2019) [IF=5.243].

33 Yang, Q., Wang, Y., Zhang, S., Tang, J., Li, F., Yin, J., Li, Y., Fu, J., Li, B., Luo, Y., Xue, W. & Zhu, F. Biomarker Discovery for Immunotherapy of Pituitary Adenomas: Enhanced Robustness and Prediction Ability by Modern Computational Tools. International journal of molecular sciences 20(1) (2019) [IF=5.923].

34 Tang, J., Fu, J., Wang, Y., Luo, Y., Yang, Q., Li, B., Tu, G., Hong, J., Cui, X., Chen, Y., Yao, L., Xue, W. & Zhu, F. Simultaneous Improvement in the Precision, Accuracy, and Robustness of Label-free Proteome Quantification by Optimizing Data Manipulation Chains. Molecular & cellular proteomics : MCP 18(8): 1683-1699 (2019) [IF=5.911].

35 Nie, X., Wei, J., Hao, Y., Tao, J., Li, Y., Liu, M., Xu, B. & Li, B. Consistent Biomarkers and Related Pathogenesis Underlying Asthma Revealed by Systems Biology Approach. International journal of molecular sciences 20(16) (2019) [IF=5.923, Corresponding author].

36 Li, X., Li, X., Li, Y., Yu, C., Xue, W., Hu, J., Li, B., Wang, P. & Zhu, F. What Makes Species Productive of Anti-Cancer Drugs? Clues from Drugs' Species Origin, Druglikeness, Target and Pathway. Anti-cancer agents in medicinal chemistry 19(2): 194-203 (2019) [IF=2.505].

37 Hu, J., Yin, H., Li, B. & Yang, H. Identification of Transcriptional Metabolic Dysregulation in Subtypes of Pituitary Adenoma by Integrated Bioinformatics Analysis. Diabetes, metabolic syndrome and obesity : targets and therapy 12: 2441-2451 (2019) [IF=3.168, Corresponding author].

38 Cui, X., Yang, Q., Li, B., Tang, J., Zhang, X., Li, S., Li, F., Hu, J., Lou, Y., Qiu, Y., Xue, W. & Zhu, F. Assessing the Effectiveness of Direct Data Merging Strategy in Long-Term and Large-Scale Pharmacometabonomics. Frontiers in pharmacology 10: 127 (2019) [IF=5.810, Co-first author].

39 Mei, T., Fu, W. B., Li, B., He, Z. B. & Chen, B. Comparative genomics of chemosensory protein genes (CSPs) in twenty-two mosquito species (Diptera: Culicidae): Identification, characterization, and evolution. PloS one 13(1): e0190412 (2018) [IF=3.240].

40 Ding, Y. R., Li, B., Zhang, Y. J., Mao, Q. M. & Chen, B. Complete mitogenome of Anopheles sinensis and mitochondrial insertion segments in the nuclear genomes of 19 mosquito species. PloS one 13(9): e0204667 (2018) [IF=3.240].

41 Yang, Q., Li, B. & Zhu, F. in Proceedings of the 5th International Conference on Bioinformatics and Computational Biology.  17-20.

42 Yang, F., Fu, T., Zhang, X., Hu, J., Xue, W., Zheng, G., Li, B., Li, Y., Yao, X. & Zhu, F. Comparison of computational model and X-ray crystal structure of human serotonin transporter: potential application for the pharmacology of human monoamine transporters. Molecular Simulation 43(13-16): 1089-1098 (2017) [IF=2.178].

43 Wang, P., Zhang, X., Fu, T., Li, S., Li, B., Xue, W., Yao, X., Chen, Y. & Zhu, F. Differentiating Physicochemical Properties between Addictive and Nonaddictive ADHD Drugs Revealed by Molecular Dynamics Simulation Studies. ACS chemical neuroscience 8(6): 1416-1428 (2017) [IF=4.418].

44 Li, B., Tang, J., Yang, Q., Li, S., Cui, X., Li, Y., Chen, Y., Xue, W., Li, X. & Zhu, F. NOREVA: normalization and evaluation of MS-based metabolomics data. Nucleic acids research 45(W1): W162-w170 (2017) [IF=16.971, First author].

45 郑国勋, 薛伟伟, 王盼盼, 杨凤园, 李勃, 李晓凤, 李映红 & 朱峰. in 中国化学会第30届学术年会-第二十五分会:化学信息学与化学计量学.  1.

46 Zheng, G., Xue, W., Wang, P., Yang, F., Li, B., Li, X., Li, Y., Yao, X. & Zhu, F. Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study. Scientific reports 6: 26883 (2016) [IF=4.379].

47 Xue, W., Wang, P., Li, B., Li, Y., Xu, X., Yang, F., Yao, X., Chen, Y. Z., Xu, F. & Zhu, F. Identification of the inhibitory mechanism of FDA approved selective serotonin reuptake inhibitors: an insight from molecular dynamics simulation study. Physical chemistry chemical physics : PCCP 18(4): 3260-3271 (2016) [IF=3.676].

48 Li, B., Tang, J., Yang, Q., Cui, X., Li, S., Chen, S., Cao, Q., Xue, W., Chen, N. & Zhu, F. Performance Evaluation and Online Realization of Data-driven Normalization Methods Used in LC/MS based Untargeted Metabolomics Analysis. Scientific reports 6: 38881 (2016) [IF=4.379, First author].

49 Jing, Y., Li, B., Chen, N., Li, X., Hu, J. & Zhu, F. The discrimination of learning styles by Bayes-based statistics: An extended study on ILS system. Control and Intelligent Systems 43(2): 68-75 (2015) [EI, Co-first author].

50 Jia, X., Liu, S., Zheng, H., Li, B., Qi, Q., Wei, L., Zhao, T., He, J. & Sun, J. Non-uniqueness of factors constraint on the codon usage in Bombyx mori. BMC genomics 16(1): 356 (2015) [IF=3.969].

51 高山, 张宁, 李勃, 徐硕, 叶彦波 & 阮吉寿. 下一代测序中ChIP-seq数据的处理与分析. 遗传 34(06): 773-783 (2012).

52 陈园园, 李勃 & 邓林红. 基于强迫振荡技术的呼吸道阻力及其可变性测量. 医用生物力学 27(04): 460-463 (2012).

53 Long, J., Li, M., Ren, Q., Zhang, C., Fan, J., Duan, Y., Chen, J., Li, B. & Deng, L. Phylogenetic and molecular evolution of the ADAM (A Disintegrin And Metalloprotease) gene family from Xenopus tropicalis, to Mus musculus, Rattus norvegicus, and Homo sapiens. Gene 507(1): 36-43 (2012) [IF=3.688].

54 李勃, 熊海燕, 陈红星 & 邓继先. 猪血清白蛋白基因5′端调控区的克隆与分析. 广西师范大学学报(自然科学版) 27(03): 58-61 (2009) [中文核心, 第一作者]