Publications in CCZU:

19. Chen, Sheng-yu ⁺, Tang, Lu-ning⁺*, and Chen, Ming*.  Palladium-Catalyzed Double ipso-Defluoroetherification of Allylic gem-Difluorides with Phenols or Alcohols. 

Org. Lett. 2024, 26, Accepted. 

18. Yang, Sen⁺,  Qiu, Chao-Ying⁺, Hu, Hao, Jiang, Yan* and Chen Ming*. Visible-Light-Driven Synthesis of N-Alkyl α-Amino Acid Derivatives from Unactivated Alkyl Bromides and in situ Generated Imines.

Org. Lett. 2024, 26, 8416−8423. DOI：10.1021/acs.orglett.4c03297.

17. Wang, Huan†.; Wang, Yi-bin†.; Zhan, Yan-fang.; Zhu, Yi-ting.; Jiang, Yan*.; Yang, Sen*.; and Chen, Ming* Copper-Catalyzed Oxidative α-Double Bond Construction in α-Amino Carbonyl Compounds via Homo-Coupling with Arylamine Release.

Org. Lett. 2024, 26, 8128−8133. DOI：10.1021/acs.orglett.4c0304.

16. Sheng, Xia-xin.;^† Qiu, Chao-ying.;^† Wang, Li-na .;^† Du, Yu-jia.; Tang, Lu-ning.; Chen, Jia-ming.; Liu, Guo-ying.; Yang, Sen*, Zheng, Peng-fei*.; and Chen, Ming*.  Transition-Metal-Free Radical Relay Cascade Annulation of Amides: Access to Antitumor Active Benzo[b]azepine and Oxindole Derivatives. 

Chem. Eur. J. 2024, e202402402. DOI: 10.1002/chem.202402402.

15. Zhan, Yan-fang⁺.; Jia-ming Chen⁺.; Sheng, Xia-xin.; Qiu, Chao-ying.; Jiang, Yan*, Yang, Sen*.; and Chen Ming*.  Photoinduced Copper Catalyzed Nitrogen-to-Alkyl Radical Relay Sonogashira-type Coupling of o-Alkylbenzamides with Alkynes. 

Chem. Commun. 2024,  60, 7906 - 7909. DOI: 10.1039/D4CC02861A.

14. Yang, Sen.;⁺,  Cai, Sha-sha.;⁺, Li, Jun-hua and Chen Ming.*  Photoinduced Palladium-Catalyzed Radical Heck-Type Coupling of Cyclobutanone Oxime Esters with Vinyl Arenes.

 J. Org. Chem. 2024, 89, 7243-7254. doi.org/10.1021/acs.joc.4c00703.

13. Liu, Guo-ying ⁺, Tang, Lu-ning⁺*, Li, Jun-hua, Yang Sen* and Chen Ming *.  Palladium-Catalyzed Alkynylation of Allylic gem-Difluorides.

 Chem. Commun. 2024, 60, 4471 - 4474. DOI: 10.1039/D4CC01007H.

12. Du, Yu-jia†, Sheng, Xia-xin†, Tang, Lu-ning, Chen, Jia-ming, Liu, Guo-ying, Hu, Hao, Yang, Sen*, Zhu Lei*, and Chen, Ming*.  Accessing Benzoazepine Derivatives via Photoinduced Radical Relay Formal [5+2] of Amide/Alkyne Enabled by Palladium Catalysis.   

Org. Lett. 2024, 26, 2662-2667. DOI：10.1021/acs.orglett.4c00979.

11.  Tang, Lu-ning.; Liu, Guo-ying.; Li, Jun-hua and  Chen, Ming.*  Palladium-Catalyzed Diversified Synthesis of mono-Fluorinated Alkenes from Allylic gem-Difluorides through Pd-OH intermediate. 

Org. Lett. 2023, 25, 9064-9069. DOI:10.1021/acs.orglett.3c03917. 

Highlight by Organic Chemistry Portal, https://www.organic-chemistry.org/abstracts/lit9/362.shtm

10.  Yang, Sen.; Hu, Hao.; Li, Jun-hua and  Chen, Ming.*  Direct Alkylation of Glycine Derivatives via Photoinduced Palladium Catalysis, Utilizing Intermolecular Hydrogen Atom Transfer Mediated by Alkyl Radicals. 

ACS Catalysis. 2023, 13, 24, 15652−15662. DOI:10.1021/acscatal.3c04075.

9. Kong, Xian-qiang.; Chen, Yi-yi.; Chen, Xiao-hui.; Ma, Cheng.; Chen, Ming.; Wang, Wei.; Xu, Yuan-Qing.; Ni, Shao-Fei.; Cao, Zhong-Yan.*  Organomediated electrochemical fluorosulfonylation of aryl triflates via selective C–O bond cleavage. 

Nat. Commun. 2023,14, 6933. DOI: 10.1038/s41467-023-42699-0.

8. Yang, Sen.; Hu, Hao.; and  Chen, Ming.*  Photoinduced Palladium-Catalyzed Regio- and Chemoselective Elimination of Primary Alkyl Bromides: A Mild Route to Synthesize Unactivated Terminal Olefins. 

Org. Lett. 2023, 25, 7968-7973. DOI: 10.1021/acs.orglett.3c02980.

7.  Chen, Jia-ming.; Li, Jun-hua.; Xie, Li-cheng.; Fan, Hui-ke.; Sheng, Xia-xin.; Du, Yu-jia.; Liu, Guo-ying.; Hu, Hao.; Jiang, Yan*.; and Chen, Ming.*   Iron-Catalyzed Divergent Approach to Naphthyridinones and Quinolinones: Leveraging Povarov and Carbonyl-Alkyne Metathesis Reactions of Electron Deficient Alkynes.

 Org. Chem. Front. 2023, 10, 5505-5511. DOI:10.1039/D3QO01302B.

6.  Li, Pei-shang.; Teng, Qiaoqiao*.; and Chen, Ming.*  Photoinduced Radical Cascade Domino Heck Coupling of N-Aryl Acrylamide with Vinyl Arenes Enabled by Palladium Catalysis. 

Chem. Commun. 2023, 59, 10620-10623.  DOI: 10.1039/D3CC03506A.

5. Yang, Sen.; Guo-ying, Liu.;  Fan, Huike.; Jun-hua, Li.; Teng, Qiaoqiao*.; and Chen, Ming.*  Sodium Hydroxide (NaOH)-Mediated Oxidative Hydroxylation of Arylboronic Acids and Its Applications in C-O Bond Formation. 

Eur. J. Org. Chem. 2023, e202300517. DOI: 10.1002/ejoc.202300517. (Dedicated to celebrate the 45th anniversary of Changzhou University)

4. Sheng, Xiaxin^†.; Du, Yujia^†.; Li, Junhua.; Teng, Qiaoqiao.*; and  Chen, Ming.* Photo-induced Nitrogen-to-Alkyl Radical Relay Heck Reaction of o-Alkylbenzamide with Vinyl Arenes by Palladium Catalysis. 

Org. Lett. 2023, 25, 3664-3669. DOI : 10.1021/acs.orglett.3c01030.

3. Du, Yujia^†.; Sheng, Xiaxin^†.; Li, Junhua.; Chen, Jiaming.; Yang, Sen. *; and  Chen, Ming.*  Aryl-to-Alkyl Radical Relay Heck Reaction of Amides with Vinyl Arenes. 

Chem. Sci. 2023, 14, 3580-3586. DOI: 10.1039/D2SC06852D.

2. Fan, Huike, Yang, Sen.; Li, Junhua.; Teng, Qiaoqiao*.; and Chen, Ming.* BaO-Catalyzed α-Deuteration of Ketones, Sulfones, Sulfoxides, and Nitriles. 

Eur. J. Org. Chem. 2022, e202201218. DOI: 10.1002/ejoc.202201218.









1. Yang, Sen.; Fan, Huike.; Xie, Licheng.; Dong, Guangbin*.; and Chen, Ming.*  Photoinduced Desaturation of Amides by Palladium Catalysis. 

Org. Lett. 2022, 24, 6460-6465.

Publications prior to CCZU::

1. Chen, M.; Chen, Y.; Sun, N.; Zhao, J.; Liu, Y.* Gold-Catalyzed Oxidative Ring Expansion of 2-Alkynyl-1,2-Dihydropyridines or -quinolines: Highly Efficient Synthesis of Functionalized Azepine or Benzazepine Scaffolds. Angew. Chem. Int. Ed. 2015, 54, 1200.

2. Chen, M.; Dong, G.* Direct Catalytic Desaturation of Lactams Enabled by Soft Enolization.J. Am. Chem. Soc.2017, 139,7757.(Highlighted by Org. Process Res. Dev.2017, 21, 1873.)

3. Chen, M.; Liu, F.; Dong, G.*Direct Palladium-Catalyzed β-Arylation of Lactams. Angew. Chem. Int. Ed. 2018,57, 3815.

4. Chen, M; Rago, A; Dong, G* Platinum-Catalyzed Desaturation of Lactams, Ketones and Lactones.Angew. Chem. Int. Ed.2018, 57, 16205-16209.(Highlighted bySynfacts,2019, 173)

5. Chen, M.; Dong, G.* Copper-Catalyzed Desaturation of Lactones, Lactams and Ketones under pH-Neutral Conditions. J. Am. Chem. Soc. 2019, 141,14889.

6. Chen, M.; Dong, G.*Platinum‐catalyzed α,β‐Desaturation of Cyclic Ketones through Direct Metal‐enolate Formation” Angew. Chem. Int. Ed. 2021, 60(14), 7956-7961.

7. Chen, M.; Chen, Y.; Liu, Y.* Palladium-catalyzed highly efficient synthesis of tetracenes and Pentacenes.Chem. Commun.2012,48, 12189-12191.

8. Chen, M.; Liu, J.; Wang, L.; Zhou, X.; Liu, Y.* Gold-catalyzed cascade cycloisomerization of1,7-diyn-3,6-bis(propargyl carbonate)s: stereoselective synthesis of naphtho[b]cyclobutenes.Chem. Commun.2013,49, 8650-8652. (Highlighted bySynfacts,2014, 144)

9. Chen, M.; Sun, N.; Liu, Y.*Environmentally Benign Synthesis of Indeno[1,2-b]quinolines via an Intramolecular Povarov Reaction.Org.Lett.2013,15, 5574.

10. Chen, M.; Sun, N.; Xu, W.; Zhao, J.; Wang, G.; Liu, Y.* Gold-Catalyzed Ring Expansion ofalkynylheterocycle via 1,2-Migration of an Endocyclic C-Heteroatom Bond. Chem. Eur. J. 2015, 21, 18571.

11. Chen, M^†.; Sun, N^†.; Chen, H.; Liu, Y.* Dioxazoles, a new mild nitrene transfer reagent in gold catalysis: highly efficient synthesis of functionalized oxazoles. Chem. Commun.2016,52, 6324.

12. Chen, Y.;Chen, M.; Liu, Y.* Gold-Catalyzed Cyclization of 1,6-Diyne-4-en-3-ols: Stannyl Transfer from 2-Tributylstannylfuran Through Au/Sn Transmetalation. Angew. Chem. Int. Ed. 2012, 51, 6181-6186.

13. Chen, Y.;Chen, M.; Liu, Y.* Gold-Catalyzed Cascade Cyclizations of 1,6-Diynyl Carbonates to Benzo[b]fluorenes Involving Arylation of Oxocarbenium Ion Intermediates and Decarboxylative Etherification. Angew. Chem. Int. Ed. 2012, 51, 6493-6497.

14. Sun, N.;Chen, M.; Liu, Y.* Gold-Catalyzed Oxidative Reactions of Propargylic Carbonates Involving 1,2-Carbonate Migration: Stereoselective Synthesis of Functionalized Alkenes. J. Org. Chem. 2014, 79, 4055.

15. Liu, J.;Chen, M.; Zhang, L.; Liu, Y.* Gold(I)-Catalyzed 1,2-Acyloxy Migration/[3+2] Cycloaddition of 1,6-Diynes with an Ynamide Propargyl Ester Moiety: Highly Efficient Synthesis of Functionalized Cyclopenta[b]indoles. Chem. Eur. J.2015,21, 1009.

16. Li, X.; Chen, M.; Xie, X.; Sun, N.; Li, S*.; Liu, Y*. Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade. Org. Lett.2015,17, 2984.

17. Sun, R.;Liu, J.;Yang, S.;Chen, M.; Sun, N.; Chen, H.; Xie, X.; You, X.; Li, S.; Liu, Y.* Cp₂TiCl₂-Catalyzedcis-Hydroalumination of Propargylic Amines with Red-Al: Stereoselective Synthesis ofZ-Configured Allylic Amines. Chem. Commun. 2015, 51, 6426.

18. Xu, W.; Chen, M.; Sun, N.; Liu, Y.* Gold-catalyzed cyclization of 1,6-diynyl dithioacetals via 1,7-carbene transfer and aromatic C–H functionalization. Chem. Commun. 2016, 52, 11000.

19. Hu, H^†.; Hu, X^†.;Chen, M.; Sun, N.;* Liu, Y.* Gold-Catalyzed Ring Expansion Reaction: Highly Efficient Synthesis of Functionalized 2,3-Benzodiazepine Scaffolds. Chin. J. Org. Chem. 2018, 38, 190.