Publications since 2020:

Zheng H#, Qi Y#, Hu S#, Cao X#, Xu C#, Yin Z, Chen X, Li Y, Liu W, Li J, Wang J, Wei G, Liang K, Chen FX*, Xu Y*.(2020) Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. Science. 2020 Nov 27;370(6520):eabb5872.

 (# First author; * Corresponding author)

Selected Publications before independence:

Chen FX#, Smith ER, Shilatifard A*. Born to run: Control of RNA polymerase II transcription elongation. Nature Reviews Molecular Cell Biology. 2018 May 8. doi:10.1038/s41580-018-0010-5.

Chen FX#, Xie P, Collings CK, Cao K, Marshall SA, Rendleman EJ, Ugarenko M, Zhang A, Shiekhattar R, Smith ER, Shiekhattar R, Zhang MQ, Shilatifard A*. PAF1 regulation of promoter-proximal pause release via enhancer activation. Science. 2017 Sep 22;357(6357):1294-1298.

Chen FX#, Woodfin AR, Gardini A, Rickels RA, Marshall SA, Smith ER, Shiekhattar R, Shilatifard A*. PAF1, a molecular regulator of promoter-proximal pausing by RNA polymerase II. Cell. 2015 Aug;162(5):1003-1015. (Highlighted by Nature Reviews Molecular Cell Biology, “PAF1 regulates promoter-proximal pausing”)

Chen F#, Gao X, Shilatifard A*. Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide. Genes & Development. 2015 Jan 1;29(1):39-47.

Chen FX*#, Marshall SA, Deng Y, Tianjiao S. Measuring Nascent Transcripts by Nascent-seq. Methods in Molecular Biology. 2018;1712:19-26.

Chen F#, Yang H#, Dong Z#, Fang J, Wang P, Zhu T, Gong W, Fang R, Shi YG, Li Z*, Xu Y*. Structural insight into substrate recognition by histone demethylase LSD2/KDM1b. Cell Research. 2013 Feb;23(2):306.

Fang R#, Chen F#, Dong Z, Hu D, Barbera AJ, Clark EA, Fang J, Yang Y, Mei P, Rutenberg M, Li Z, Zhang Y, Xu Y, Yang H, Wang P, Simon MD, Zhou Q, Li J, Marynick MP, Li X, Lu H, Kaiser UB, Kingston RE, Xu Y*, Shi YG*. LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation. Molecular Cell. 2013 Feb 7;49(3):558-70.

Huang YH#, Hu J, Chen F, Lecomte N, Basnet H, David CJ, Witkin MD, Allen PJ, Leach SD, Hollmann TJ, Iacobuzio-Donahue CA, Massague J*. ID1 mediates escape from TGF-β tumor suppression in pancreatic cancer. Cancer Discovery. 2019 Oct 3. pii: CD-19-0529.

See full publication list on Pubmed