徐从玲,2011年本科毕业于烟台大学生命科学学院,2018年博士毕业于上海交通大学医学院附属瑞金医院,2018至今于复旦大学附属肿瘤医院(与徐彦辉教授共同指导)进行博士后研究。博士期间的研究方向为乳腺癌和胰腺癌的发生发展的机制研究,目前的主要的研究方向为:1)TGF-b信号通路及其下游转录因子在肿瘤中的转录调控机制研究;2)新的转录调控复合物的转录调控机制研究;3)临床肿瘤样本的单细胞测序及单细胞空间转录组测序研究。
Publications:
Zheng H#, Qi Y#, Hu S#, Cao X#, Xu C#, Yin Z, Chen X, Li Y, Liu W, Li J, Wang J, Wei G, Liang K, Chen FX*, Xu Y*.(2020) Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. Science. 2020 Nov 27;370(6520):eabb5872.
Xu C, Wang X, Zhou Y, et al. Synergy between arsenic trioxide and JQ1 on autophagy in pancreatic cancer. Oncogene. 2019;38(47):7249-7265.
Li K, Xu C, Du Y, Junaid M, Kaushik AC, Wei DQ. Comprehensive epigenetic analyses reveal master regulators driving lung metastasis of breast cancer. J Cell Mol Med. 2019;23(8):5415-5431.
Wang X, Fan H, Xu C, et al. KDM3B suppresses APL progression by restricting chromatin accessibility and facilitating the ATRA-mediated degradation of PML/RARα. Cancer Cell Int. 2019;19:256. Published 2019 Oct 4.
Jiang G, Wang X, Sheng D, Zhou L, Liu Y, Xu C, . Cooperativity of co-factor NR2F2 with Pioneer Factors GATA3, FOXA1 in promoting ERα function. Theranostics. 2019;9(22):6501-6516.
Shared genetic and epigenetic mechanisms between chronic periodontitis and oral squamous cell carcinoma. Oral Oncol. 2018;86:216-224.