陈吉伟，2011年本科毕业于西北农林科技大学生命科学学院，2017年博士毕业于华东师范大学生命科学学院，2018年至2021年5月于华东师范大学进行博士后训练。博士及博士后期间主要研究方向为：多组学生物大数据的整合与解析及转录调控、蛋白质互作等生物分子调控网络的构建分析。

Publications:

1. Ding Wubin(#), Chen Jiwei(#), Feng Guoshuang(#), Chen Geng, et al. DNMIVD: DNA methylation interactive visualization database. Nucleic Acids Research, 2020. 48(D1): p. D856-D862.

2. Chen Geng(#), Chen Jiwei(#), Liu Huanlong, Chen Shuangguan, et al. Comprehensive identification and characterization of human secretome based on integrative proteomic and transcriptomic data. Frontiers in Cell and Developmental Biology, 2019. 299(7).

3. Gao Ganglong(#), Wei Gaigai(#), Liu Shijie(#), Chen Jiwei(#), et al. Epithelial Wntless is dispensable for intestinal tumorigenesis in mouse models. Biochemical and Biophysical Research Communications, 2019. 519(4): p. 754-760. IF：2.985

4. Wei Wei(#), Liu Xiaoguang(#), Chen Jiwei(#), Gao Shennan, et al. Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription. Cell Research, 2017. 27(7): p. 898-915.

5. Yang Yeran(#), Chen Jiwei(#), Qin Hong(#), Jin Yaqiong, et al. Whole genome sequencing identifies novel compound heterozygous BRCA2 gene mutations associated with peripheral neuroblastic tumors. Frontiers in Genetics. 2021 (Accepted). 

6. Chen Jiwei, Li Yunjin, Chen Geng(*). Single-cell analysis of alternative splicing and gene regulatory network reveals remarkable expression and regulation dynamics during early embryonic development. Aging-US, 2021 (Revised).

7. Wei Gaigai(#), Gao Na(#), Chen Jiwei, Fan Lingling, et al. Erk1/2 mediated negative feedback regulation is essential for postnatal intestinal development and homeostasis. Development, 2020.147(17).

8. Li Yunjin, Chen Jiwei, Xu Qiyue, Han Zebei, et al. Single-cell transcriptomic analysis reveals dynamic alternative splicing and gene regulatory networks among pancreatic islets. Science China Life Sciences, 2020.

9. Yu Fang(#), Shi Guang(#), Cheng Shimeng, Chen Jiwei, et al. SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation. Cell Research, 2018. 28(6): p. 670-685.

10. Chen Geng, Chen Jiwei, Yang Jianmin, Chen Long, et al. Significant variations in alternative splicing patterns and expression profiles between human-mouse orthologs in early embryos. Science China Life Sciences, 2017. 60(2): p. 178-188.

11. Wu Meng(#), Wei Wei(#), Chen Jiwei, Cong Rong, et al. Acidic domains differentially read histone H3 lysine 4 methylation status and are widely present in chromatin-associated proteins. Science China Life Sciences, 2017. 60(2): p. 138-151.

12. Lai Mi, Liang Lizhu, Chen Jiwei, Qiu Naiqi, et al. Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT). Molecular & Cellular Proteomics, 2016. 15(7): p. 2263-78.

13. Chen Geng, Yang Juan, Chen Jiwei, Song Yunjie, et al. Identifying and annotating human bifunctional RNAs reveals their versatile functions. Science China Life Sciences, 2016. 59(10): p. 981-992.

14. Chen Geng(#), Yu Dianke(#), Chen Jiwei, Cao Ruifang, et al. Re-annotation of presumed noncoding disease/trait-associated genetic variants by integrative analyses. Scientific Reports, 2015. 5: p. 9453.

15. Chen Geng, Chen Jiwei, Shi Caiping, Shi Leming, et al. Dissecting the Characteristics and Dynamics of Human Protein Complexes at Transcriptome Cascade Using RNA-Seq Data. PLoS One, 2013. 8(6): p. e66521.