1. Baoyu Zhao, Pengbiao Xu, Chesley M. Rowlett, Tao Jing, Omkar Shinde,

Yuanjiu Lei, A. Phillip West, Wenshe Ray Liu and Pingwei Li. The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS. Nature 587, 673–677 (2020)

2. Baoyu Zhao, Fenglei Du, Pengbiao Xu, Chang Shu, Banumathi Sankaran, Samantha L. Bell, Mengmeng Liu, Yuanjiu Lei, Xinsheng Gao, Xiaofeng Fu, Fanxiu Zhu, Yang Liu, Arthur Laganowsky, Xueyun Zheng, Jun-Yuan Ji, A. Phillip West, Robert O. Watson & Pingwei Li. A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1. Nature, 569, 718–722 (2019)

3. Baoyu Zhao, Guanghui Yi, Fenglei Du, Yin-Chih Chuang, Robert C. Vaughan, Banumathi Sankaran, C. Cheng Kao & Pingwei Li. Structure and function of the Zika virus full-length NS5 protein. Nature Communications, 8, 14762 (2017)

(This work was recommended by F1000 (Faculty of 1000) and selected as Science Highlights by Advanced Light Source/Lawrence Berkeley National Laboratory)

4. Baoyu Zhao, Chang Shu, Xinsheng Gao, Banumathi Sankaran, Fenglei Du, Catherine L. Shelton, Andrew B. Herr, Jun-Yuan Ji, and Pingwei Li. Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins. Proc. Natl. Acad. Sci. USA, 113 (24), E3403-E3412 (2016)

5. Baoyu Zhao, Sonu Gandhi, Cai Yuan, Zhipu Luo, Rui Li, Henrik
Gårdsvoll, Valentina de Lorenzi, Nicolai Sidenius, Mingdong Huang, Michael Ploug. Mapping the topographic epitope landscape on the urokinase plasminogen activator receptor (uPAR) by surface plasmon resonance and X-ray crystallography. Data in brief, 5, 107-113 (2015)

6. Baoyu Zhao, Sonu Gandhi, Cai Yuan, Zhipu Luo, Rui Li, Henrik
Gårdsvoll, Valentina de Lorenzi, Nicolai Sidenius, Mingdong Huang, Michael Ploug. Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. Journal of Molecular Biology, 427 (6 Pt B), 1389-1403 (2015)

7. Baoyu Zhao, Peng Xu, Longguang Jiang, Berit Paaske, Tobias Kromann-Hansen, Jan K. Jensen, Hans Peter Sørensen, Zhuo Liu, Jakob T. Nielsen, Anni Christensen, Masood Hosseini, Kasper K. Sørensen, Niels Christian Nielsen, Mingdong Huang, Peter A. Andreasen. A Cyclic Peptidic Serine Protease Inhibitor: Increasing Affinity by Increasing Peptide Flexibility. PLoS ONE, 9 (12), e115872 (2014)

8. Baoyu Zhao, Cai Yuan, Rui Li, Dan Qu, Mingdong Huang, and Jacky Chi Ki Ngo. Crystal Structures of Matriptase in Complex with Its Inhibitor Hepatocyte Growth Factor Activator Inhibitor-1. Journal of Biological Chemistry, 288 (16), 11155-11164 (2013)

9. Iktae Kim, Alyssa Dubrow, Bryan Zuniga, Baoyu Zhao, Noah Sherer, Abhishek Bastiray, Pingwei Li, Jae-Hyun Cho. Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus. Nature Communications, 13(1): 5775 (2022)

10. Chi G. Weindel, Eduardo L. Martinez, Xiao Zhao, Cory J. Mabry, Samantha L. Bell, Krystal J. Vail, Aja K. Coleman, Jordyn J. VanPortfliet, Baoyu Zhao, Allison R. Wagner, Sikandar Azam, Haley M. Scott, Pingwei Li, A. Phillip West, Jason Karpac, Kristin L. Patrick, Robert O. Watson. Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis. Cell, 185(17):3214-3231.e23. (2022)

11. Jun Liu, Yanyan Huang, Liang Kong, Xiao Yu, Baomin Feng, Derui Liu, Baoyu Zhao, Giselle C. Mendes, Peiguo Yuan, Dongdong Ge, Wen-Ming Wang, Elizabeth P. B. Fontes, Pingwei Li, Libo Shan and Ping He. The malectin-like receptor-like kinase LETUM1 modulates NLR protein SUMM2 activation via MEKK2 scaffolding. Nature Plants, 6, 1106–1115 (2020)

12. Tao Jing, Baoyu Zhao, Pengbiao Xu, Xinsheng Gao, Lei Chi, Huajun Han, Banumathi Sankaran and Pingwei Li. The Structural Basis of IRF-3 Activation upon Phosphorylation. The Journal of Immunology 205 (7):1886-1896 (2020)

13. Kai S. Yang, Xinyu R. Ma, Yuying Ma, Yugendar R. Alugubelli, Danielle A. Scott, Erol C. Vatansever, Aleksandra K. Drelich, Banumathi Sankaran, Zhi Z. Geng, Lauren R. Blankenship, Hannah E. Ward, Yan J. Sheng, Jason C. Hsu, Kaci C. Kratch, Baoyu Zhao, Hamed S. Hayatshahi, Jin Liu, Pingwei Li, Carol A. Fierke, Chien-Te K. Tseng, Shiqing Xu and Wenshe Ray Liu. A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors. ChemMedChem, doi: 10.1002/cmdc.202000924 (2020)

14. Jae-Hyun Cho, Baoyu Zhao, Jie Shi, Nowlan Savage, Qingliang Shen, James Byrnes, Lin Yang, Wonmuk Hwang, and Pingwei Li. Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses. Proc. Natl. Acad. Sci. USA, 117 (12), 6550-6558 (2020)

15. Xiaofei Zhou, Jiayi Yu, Xuhong Cheng, Baoyu Zhao, Ganiraju C Manyam, Li Zhang, Kimberly Schluns, Pingwei Li, Jing Wang, and Shao-Cong Sun. The deubiquitinase Otub1 controls the activation of CD8 T cells and NK cells by regulating IL-15-mediated priming. Nature Immunology, 20, 879-889 (2019)

16. Xin Li, Meng Deng, Alex S. Petrucelli, Cheng Zhu, Jinyao Mo, Lu Zhang, Jason W. Tam, Pablo Ariel, Baoyu Zhao, Song Zhang, Hengming Ke, Pingwei Li, Nikolay V. Dokholyan, Joseph A. Duncan, and Jenny P.-Y. Ting. Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon. Immunity, 50, 591-599 (2019)

17. Arundhati Ghosh, Lulu Shao, Padmavathi Sampath, Baoyu Zhao, Nidhi V. Patel, Jianzhong Zhu, Bharat Behl, Robert A. Parise, Jan H. Beumer, Roderick J. O’Sullivan, Neal A. DeLuca, Stephen H. Thorne, Vijay A.K. Rathinam, Pingwei Li, Saumendra N.Sarkar. Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production. Immunity, 50, 51-63 (2019)

18. Xiaoping Xie, Jin Jin, Lele Zhu, Zuliang Jie, Yanchuan Li, Baoyu Zhao, Xuhong Cheng, Pingwei Li and Shao-Cong Sun. Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction. Cell & Bioscience, 9, 5 (2019)

19. Xavier Lahaye, Matteo Gentili, Aymeric Silvin, Cécile Conrad, Léa Picard, Mabel Jouve, Elina Zueva, Mathieu Maurin, Francesca Nadalin, Gavin J. Knott, Baoyu Zhao, Fenglei Du, Marlène Rio, Jeanne Amiel, Archa H. Fox, Pingwei Li, Lucie Etienne, Charles S. Bond, Laurence Colleaux, Nicolas Manel. NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation. Cell, 175, 488-501 (2018)

20. Qingliang Shen, Jie Shi, Danyun Zeng, Baoyu Zhao, Pingwei Li, Wonmuk Hwang, Jae-Hyun Cho. Molecular Mechanisms of Tight Binding through Fuzzy Interactions. Biophysical Journal, 114 (6), 1313-1320 (2018)

21. Tuanyu Guo, Baoyu Zhao, Cai Yuan, Mingdong Huang. Expression, Purification and Crystallization of Inactivated Serine Protease Domain of Matriptase. The Chinese Journal of Process Engineering, 17 (4), 834-838 (2017)

22. Qingliang Shen, Danyun Zeng, Baoyu Zhao, Veer S. Bhatt, Pingwei Li, and Jae-Hyun Cho. The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus. ACS Chemical Biology, 12 (5), 1199–1203 (2017)

23. Min Liu, Cai Yuan, Jan Jensen, Baoyu Zhao, Yunbin Jiang, Longguang Jiang, Mingdong Huang. The Crystal Structure of a Membrane-bound Multi-domain Protease Inhibitor Reveals the Mechanism of Its Auto-inhibition. Journal of Biological Chemistry, 292, 8412-8423 (2017)

24. Longguang Jiang, Baoyu Zhao, Peng Xu, Hans Peter Sørensen, Jan K. Jensen, Anni Christensen, Masood Hosseini, Niels Christian Nielsen, Knud J. Jensen, Peter A. Andreasen, Mingdong Huang. Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues. The International Journal of Biochemistry & Cell Biology, 62, 88-92 (2015)

25. Song Chen, Yu Wang, Baoyu Zhao, Zhuo Chen, Mingdong Huang. Maltose-binding Protein Improving the Crystallizability of C2 Domain of Human Coagulation Factor V. Chinese Journal of Structural Chemistry, 33 (2), 216-222 (2014)

26. Longguang Jiang, Cai Yuan, Hongwei Chen, Yu Wang, Baoyu Zhao, Xu Zhang, Mingdong Huang. Preparation and Structure of a New Coagulation Factor XI Catalytic Domain for Drug Discovery. Chinese Journal of Structural Chemistry, 30 (7), 1021-1029 (2011)