Mechanotransduction in Embryo Development
Huang H, Gao Shaorong, Bao M*, Exploring Mechanical Forces Shaping Self-Organization and Morphogenesis During Early Embryo Development, Annual Review of Cell and Developmental Biology, 2024. [PDF]
Micropatterning and Mechanotransduction
Hu XY, Bao M*, Advances in Micropatterning Technology for Mechanotransduction Research, Mechanobiology in Medicine, 2024. [PDF]
Cell Volume and Mechanotransduction
Xie J, Huck Wilhelm*, Bao M*, Unveiling the Intricate Connection: Cell Volume as a Key Regulator of Mechanotransduction [J]. Annual Review of Biophysics, 2024. [PDF]
Geometrical Confinement and Stem Cell Fate
Bao M*#, Xie J#. Geometric Confinement-Mediated Mechanical Tension Directs Patterned Differentiation of Mouse ESCs into Organized Germ Layers[J]. ACS Applied Materials & Interfaces, 2023. [PDF]
How to Build a "Synthetic Embryo"?
Bao M*. Self-organization principles in stem-cell-derived synthetic embryo models[J]. The Innovation, 2023, 4(1): 100366. [PDF]
"Synthetic Embryo" Models
Bao M, Cornwall-Scoones J, Zernicka-Goetz M. Stem-cell-based human and mouse embryo models[J]. Current Opinion in Genetics & Development, 2022, 76: 101970. [PDF]
Adhesion and Tension in Early Embryo Development
Bao M, Cornwall-Scoones J, Sanchez-Vasquez E, et al. Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension[J]. Nature Cell Biology, 2022, 24(9): 1341-1349. [PDF]
Free Standing Microtissue and Migration
Xie J, Hu X, Chen L, Piruska A, Zheng Z, Bao M*, Huck WTS*. The Effect of Geometry and TGF‐β Signaling on Tumor Cell Migration from Free‐Standing Microtissues[J]. Advanced Healthcare Materials, 2022, 11(12): 2102696. [PDF]
Cells Sense Geometry During Gap Closure
Bao M, Xie J, Piruska A, et al. Microfabricated gaps reveal the effect of geometrical control in wound healing[J]. Advanced Healthcare Materials, 2021, 10(4): 2000630. [PDF]
Energy Consuming and Mechanotransduction
Xie J#, Bao M#, Hu X, et al. Energy expenditure during cell spreading influences the cellular response to matrix stiffness[J]. Biomaterials, 2021, 267: 120494. [PDF]
Sozen B, Cox A L, De Jonghe J, Bao M, et al. Self-organization of mouse stem cells into an extended potential blastoid[J]. Developmental Cell, 2019, 51(6): 698-712. e8. [PDF]
Gungordu H I, Bao M, Van Helvert S, et al. Effect of mechanical loading and substrate elasticity on the osteogenic and adipogenic differentiation of mesenchymal stem cells[J]. Journal of Tissue Engineering and Regenerative medicine, 2019, 13(12): 2279-2290. [PDF]
Stem Cell Volume and Stiffness
Bao M, Xie J, Katoele N, et al. Cellular volume and matrix stiffness direct stem cell behavior in a 3D microniche[J]. ACS Applied Materials & Interfaces, 2018, 11(2): 1754-1759. [PDF]
3D Microenvironment and Cell Fate
Bao M, Xie J, Huck W T S. Recent advances in engineering the stem cell microniche in 3D[J]. Advanced Science, 2018, 5(8): 1800448. [PDF]
Ma S, Rong M, Lin P, Bao M, et al. Fabrication of 3D tubular hydrogel materials through on-site surface free radical polymerization[J]. Chemistry of Materials, 2018, 30(19): 6756-6768. [PDF]
Stem Cell Volume and Shape
Bao M, Xie J, Piruska A, et al. 3D microniches reveal the importance of cell size and shape[J]. Nature Communications, 2017, 8(1): 1962. [PDF]
Cell Spreading
Bruekers S M C, Bao M, Hendriks J M A, et al. Adaptation trajectories during adhesion and spreading affect future cell states[J]. Scientific Reports, 2017, 7(1): 12308. [PDF]
Cells Deform Local Matrix
Xie J#, Bao M#, Bruekers S M C, et al. Collagen gels with different fibrillar microarchitectures elicit different cellular responses[J]. ACS Applied Materials & Interfaces, 2017, 9(23): 19630-19637. [PDF]
Bao M, Wang X, Yuan H, et al. HAp incorporated ultrafine polymeric fibers with shape memory effect for potential use in bone screw hole healing[J]. Journal of Materials Chemistry B, 2016, 4(31): 5308-5320. [PDF]
Bao M, Lou X, Zhou Q, et al. Electrospun biomimetic fibrous scaffold from shape memory polymer of PDLLA-co-TMC for bone tissue engineering[J]. ACS Applied Materials & Interfaces, 2014, 6(4): 2611-2621. [PDF]
Bao M, Zhou Q, Dong W, et al. Ultrasound-modulated shape memory and payload release effects in a biodegradable cylindrical rod made of chitosan-functionalized PLGA microspheres[J]. Biomacromolecules, 2013, 14(6): 1971-1979. [PDF]
