研究领域：肿瘤微环境在肿瘤发生发展中的作用机制研究；
                小分子抑制剂及其它抗肿瘤药物的基础研发；
                细菌与宿主细胞的互作机制。

主持科研项目（课题）及人才计划项目情况
1.国家自然科学基金地区科学基金项目，31860309，细胞核FAK对胃癌细胞增殖、迁移及侵袭的调控作用机制，2019/01-2022/12。
2.内蒙古自治区留学回区人员启动项目，FAK在TNFα诱导癌细胞表达炎性细胞因子中的作用机制，2017/10-2020/10。
3.内蒙古自治区自然科学基金博士基金项目，2016BS0304，肿瘤微环境黏着斑激酶在肿瘤坏死因子-α诱导癌细胞炎性因子表达中的调控机制，2016/01-2018/12。
4.内蒙古自治区教育厅项目,NJZZ002,靶向抑制细胞黏着斑激酶活性治疗胃癌及其腹膜转移癌新方法的研究，2015/01-2016/12。
代表性研究成果：
1.Zhixin Guo#, Xiaoou Chen#, Xue Feng, Hui-fang Hao*, and Zhi-gang Wang*, The mTORC1/4EBP1/PPRRγ axis mediates insulin-induced lipogenesis by regulating lipogenic gene expression in bovine mammary epithelial cells, Journal of agricultural and food chemistry, 2019, 67(21): 6007-6018.
2. Yuting Fu#, Xu Zheng#, Xiaoyang Jia, Huifang Hao* and Zhigang wang*, A quantitative transcriptomic analysis of the physiological significance of mTOR signaling in goat fetal fibroblasts, BMC Genomics, 2016, 17:879.
3. Xu Zheng#, Wenlei Bao#, JiaofuYang, Huifang Hao* and Zhigang wang*, Focal adhesion kinase directly interacts with TSC2 through its FAT domain and tegulates cell proliferation in cashmere goat fetal fibroblasts, DNA Cell Biol, 2016, 25(9):480-488.
4.Hui-fang Hao#, Yutaka Maeda#, Takuya Fukazawa*, Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer, PLoS One, 2013, 8(8):e71093.
5.Hui-fang Hao, Munenori Takaoka, Yoshio Naomoto*, Oral administration of FAK
inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal
cancer, Biochem Biophys Res Commun, 2012, 423(4):744-749.
5.Hui-fang Hao, Yoshio Naomoto*, HSP90 and its inhibitors, Oncol Rep, 2010, 23(6):1483-1492.
6.Hui-fang Hao, Yoshio Naomoto*, Progress in researches about focal adhesion kinase in gastrointestinal tract, World J Gastroenterol, 2009, 15(47):5916-5923.
7.Hui-fang Hao, Yoshio Naomoto*, Focal adhesion kinase as potential target for cancer therapy , Oncol Rep, 2009, 22(5):973-979.