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成果及论文

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2022

1.     Mengxue Zhou#, Jiaxin Wang#, Jiaxin Pan#, Hui Wang#, Bo Hou, Yi Lai, Fengyang Wang, Zhiai Xu, Haijun Yu*. Vanguard Nanovesicles Circumvent Immune Resistance for Potentiated Immunotherapy of the Immune-Excluded Tumors. Nat Commun, Submitted.

2.     Fangmin Chen, Tianliang Li, Huijuan Zhang, Madiha Saeed, Xiaoying Liu, Lujia Huang, Xiyuan Wang, Jing Gao, Bo Hou, Yi Lai, Chunyong Ding, Zhiai Xu, Zuoquan Xie, Min Luo, Haijun Yu*. Acid-ionizable iron nanoadjuvant augments STING activation for personalized vaccination immunotherapy of cancer. Advanced Materials, 2022, 2209910.

3.     Bo Hou#, Jiayi Ye#, Junhao Li, Zhiai Xu*, Haijun Yu*. In-situ clickable prodrug nanoplatform locally activates T lymphocytes to potentiate cancer immunotherapy, Nano Today, 2022, 47, 101661.

4.     Yun Zhu#, Shunan Zhang#, Yi Lai*, Jiaxing Pan, Fangmin Chen, Tingting Wang, Fengyang Wang, Zhiai Xu, Wenjun Yang*, Haijun Yu*. Self-cooperative prodrug nanovesicles migrate immune evasion to potentiate chemoradiotherapy in head and neck cancer. Adv Sci, 2022. 2203263.

5.     Yingjie Wang#, Fangmin Chen#, Huiling Zhou, Lujia Huang, Jiayi Ye, Xiaoying Liu, Weizhong Sheng*, Weidong Gao, Haijun Yu*, Feng Wang*. Redox Dyshomeostasis with Dual Stimuli-Activatable Dihydroartemisinin Nanoparticles to Potentiate Ferroptotic Therapy of Pancreatic Cancer. Small Methods, 2022, 2200888.

6.     Huijuan Zhang,# Jiaxing Pan,# Tingting Wang, Yi Lai,* Xiaoying Liu, Fangmin Chen, Leiming Xu, Xiongwei Qu,* Xiuli Hu,* Haijun Yu*. Sequentially Activatable Polypeptide Nanoparticles for Combinatory Photodynamic-Chemotherapy of Breast Cancer. ACS Applied Materials & Interfaces, 2022, 14, 39787-39798.

7.     Jiayi Ye, Bo Hou, Madiha Saeed*, Fangmin Chen, Zhiai Xu*, Haijun Yu*. Engineered Nanomedicine Mitigates Resistance of Cancer Immunotherapy. Accounts of Materials Research, 2022, 7, 697-708.

8.     Jing Gao, Bo Hou, Qiwen Zhu, Lei Yang, Xingyu Jiang, Zhifeng Zou Xutong Li, Tianfeng Xu, Mingyue Zheng, Zhiai Xu,* Huixiong Xu*, Haijun Yu*. Engineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy. Nat Commun, 2022,13,4318.

9.     Jun-hao Li, Lu-jia Huang*, Hui-ling Zhou, Yi-ming Shan, Fang-min Chen, Vesa-Pekka Lehto, Wu-jun Xu*, Li-qiang Luo, Hai-jun Yu*. Engineered nanomedicines block the PD-1/PD-L1 axis for potentiated cancer immunotherapy. Acta Pharmacologica Sinica, 2022, 43:2749–2758.

10.  Yuanyuan Guo, Qiushuang Zhang, Qiwen Zhu, Jing Gao, Xinyuan Zhu, Haijun Yu*, Yuehua Li*, Chuan Zhang*. Copackaging photosensitizer and PD-L1 siRNA in a nucleic acid nanogel for synergistic cancer photoimmunotherapy. Sciences Advances, 2022, 8, eabn2941.

11.  Tianliang Li#, Rundi Song#, Fang Sun, Madiha Saeed, Xiaozhen Guo, JiayiYe, Fangmin Chen, Bo Hou, Qiurong Zhu, Yingjie Wang, Cen Xie, Lei Tang, Zhiai Xu, Huixiong Xu, Haijun Yu*. Bioinspired magnetic nanocomplexes amplifying STING activation of tumor-associated macrophages to potentiate cancer immunotherapy. Nano Today, 2022, 43,101400.

12.  Jiayi Ye#, Bo Hou#, Fangmin Chen, Shunan Zhang, Muya Xiong, Tianliang Li, Yechun Xu, Zhiai Xu, Haijun Yu*, Bispecific Prodrug Nanoparticles Circumventing Multiple Immune Resistance Mechanisms for Promoting Cancer Immunotherapy. Acta Pharmaceutica Sinica B, 2022;12:2695-2709.

13.  黄潞嘉#于海军*,纳米机器人,抗肿瘤的新帮手《家庭用药》,2022, 1, 32-33.

14.  Yi Lai, Yijing Dang, Qian Sun, JiaXing Pan, Haijun Yu, Wen Zhang*, Zhiai Xu * Design of an Activatable NIR-II Nanoprobe for the In Vivo Elucidation of Alzheimer’s Disease-Related Variations in Methylglyoxal Concentrations, Chemical Science, 2022;13(42):12511-12518

15.  Dengyuan Hao, Qian Meng, Bowen Jiang, Shaojin Lu, Xiujuan Xiang, Qing Pei*, Haijun Yu, Xiabin Jing, Zhigang Xie*. Hypoxia-Activated PEGylated Paclitaxel Prodrug Nanoparticles for Potentiated Chemotherapy. ACS Nano 2022, 16, 14693-14702.

16.  Yi Lai, Yijing Dang, Fenglin Li, Chunyong Ding, Haijun Yu, Wen Zhang*, Zhiai Xu*. Reactive Glycolysis Metabolite-Activatable Nanotheranostics for NIR- Fluorescence Imaging-Guided Phototherapy of Cancer. Adv Funct Mater, 2022, 2200016.

17.  Wujun Xu, Cui Pang, Chaojun Song, Jing Qian, Sara Feola, Vincenzo Cerullo, Li Fan*, Haijun Yu, Vesa-Pekka Lehto*, Black porous silicon as a photothermal agent and immunoadjuvant for efficient antitumor immunotherapy. Acta Biomaterialia, 2022, 152, 473-483.

18.  Cameron Ryall, Sanjukta Duarah, Shuo Chen*, Haijun Yu, Jingyuan Wen* Advancements in Skin Delivery of Natural Bioactive Products for Wound Management: A Brief Review of Two Decades. Pharmaceutics, 2022, 14, 1072.

 2021

19.  Lujia Huang#, Fangmin Chen#, Yi Lai*, Zhiai Xu, Haijun Yu,* Engineering Nanorobots for Tumor-targeting Drug Delivery: From Dynamic Control to Stimuli-responsive Strategy. ChemBioChem, 2021, DOI: 10.1002/cbic.202100347.(科普视频获上海药物所科普大赛一等奖)

20.  Fengqi Zhou#, Jing Gao#, Yang Tang, Zhifeng Zou, Shi Jiao, Zhaocai Zhou, Huixiong Xu, Zhi Ping Xu, Haijun Yu* Zhiai Xu*. Engineering Chameleon Prodrug Nanovesicles to Increase Antigen Presentation and Inhibit PD-L1 Expression for Circumventing Immune Resistance of Cancer. Advanced Materials, 2021, 2102668.

21.  Jing Gao#, Hanwu Zhang#, Fengqi Zhou, Bo Hou, Meiwan Chen, Zhigang Xie, Haijun Yu.* Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition. Chinese Chemical Letters. 2021, 32,1929-1936.

22.  Xiaohua Zheng, Yilan Jin, Xiao Liu, Tianqing Liu, Weiqi Wang,* Haijun Yu,* Photoactivatable Reactive Species Generator for Cancer Therapy. Bioactive Materials. (Review Article) 2021, 12, 4301-4318.

23.  Mengjiao Zhou, Xiao Liu, Fangming Chen, Lili Yang, Minjian Yuan, Dingyi Fu, Weiqi Wang*, Haijun Yu*. Stimuli-activatable nanomaterials for phototherapy of cancer. Biomedical Materials (Review Article), 2021, 16, 042008.

24.  Weiqi Wang, Yilan Jin, Xiao Liu, Fangmin Chen, Xiaohua Zheng, Tianqing Liu, Yumin Yang*, Haijun Yu*, Endogenous stimuli-activatable nanomedicine for cancer immune theranostic. Advanced Functional Materials, 2021, 2100386. 

25.  Madiha Saeed, Fangming Chen, Jiayi Ye, Yang Shi, Twan Lammers, Bruno De Geest, Zhi Ping Xu, Haijun Yu*. From design to the clinic: engineered nanobiomaterials for immune normalization therapy of cancer. Advanced Materials, 2021, 2008094.

26.  Yi Lai, Fenglin Li, Zhifeng Zou, Madiha Saeed, Zhiai Xu,* Haijun Yu,* Bio-inspired amyloid polypeptides: from self-assembly to nanostructure design and biotechnological applications. Applied Materials Today. 2021, 22, 100966.

27.  Fangmin Chen#, Yingjie Wang#, Jing Gao, Madiha Saeed, Tianliang Li, Weiqi Wang, Haijun Yu*. The advances of nanobiomaterial-based vaccination immunotherapy of cancer. Biomaterials, 2021, 270, 120709.

28.  Rundi Song#, Tianliang Li#, Jiayi Ye, Fang Sun, Madiha Saeed, Bo Hou, Jing Gao, Zhiai Xu, Haijun Yu,* Acidity-activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer. Advanced Materials 2021, 2101155.

29.  Fang Sun#, Qiurong Zhu#, Tianliang Li, Madiha Saeed, Zhiai Xu, Feisheng Zhong, Rundi Song, Manxiu Huai, Mingyue Zheng, Cen Xie, Leiming Xu*, Haijun Yu.* Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer. Advanced Sciences, 2021, 2002746.

30.  Fengqi Zhou#, Jing Gao#, Zhiai Xu,* Tianliang Li, Ang Gao, Fang Sun, Fengyang Wang, Weiqi Wang, Yong Geng, Fan Zhang, Zhi Ping Xu, Haijun Yu*. Overcoming Immune Resistance by Sequential Prodrug Nanovesicles for Promoting Chemoimmunotherapy of Cancer. Nano Today, 2021, 36, 101025.

31.  Qiurong Zhu#, Fang Sun#, Tianliang Li, Mengxue Zhou, Jiayi Ye, Aiyan Ji, Hui Wang,*Chunyong Ding,* Hao Chen, Zhiai Xu,* Haijun Yu*. Engineering Oxaliplatin Prodrug Nanoparticles for Second Near-infrared Fluorescence Imaging-Guided Immunotherapy of Colorectal Cancer. Small, 2021, 2007882.

 2020

32.  Lei Zhou#, Bo Hou#, Dangge Wang, Fang Sun, Rundi Song, Qian Shao, Hao Wang, Haijun Yu*, Yaping Li*. Engineering Polymeric Prodrug Nanoplatform for Vaccination Immunotherapy of Cancer. Nano Letters, 2020, 20, 6, 4393-4402.

33.  Xiao Liu,# Yilan Jin,# Tingting Liu, Shengju Yang, Mengxue Zhou, Weiqi Wang,* Haijun Yu*. Iron-based Theranostic Nanoplatform for Improving Chemodynamic Therapy of Cancer. ACS Biomaterials Science & Engineering (Review Article) 2020, 6, 4834–4845.

34.  Yang Tang, Gemin Fang, Fenghua Guo, Hui Zhang, Xiaoxu Chen, Liwei An, Min Chen, Li Zhou, Wenjia Wang, Tiantian Ye, Lei Zhou, Pingping Nie, Haijun Yu, Moubin Lin, Yun Zhao, Xinhua Lin, Zengqiang Yuan, Shi Jiao,* Zhaocai Zhou,* Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer. Cancer Cell, 2020, 38, 1-14.

35.  Qiwen Zhu, Madiha Saeed, Rundi Song, Tao Sun, Chen Jiang, Haijun Yu,* Dynamic covalent chemistry-regulated stimuli-activatable drug delivery systems for improved cancer therapy. Chinese Chemical Letters. 2020, 31, 1051–1059.

36.  Bin Yang#, Jing Gao#, Qing Pei#, Huixiong Xu*, Haijun Yu*. Engineering Prodrug Nanomedicine for Cancer Immunotherapy (Review Article). Advanced Sciences, 2020, 2002365.

37.  Jing Gao, Weiqi Wang, Qing Pei, Megan, S. Lord, Haijun Yu*. Engineering Nanomedicine Boosting Immunogenic Cell Death for Improved Cancer Immunotherapy. Acta Pharmacologica Sinica, 2020, 41:986-994.

38.  Xianli Hu#, Bo Hou#, Zhiai Xu, Madiha Saeed, Zhenmei Gao, Yi Lai, Tong Zhu, Fan Zhang, Wen Zhang, Haijun Yu*. Supramolecular Prodrug Nanovectors for Active Tumor Targeting and Combination Immunotherapy of Colorectal Cancer. Adv Sci. 2020, 1903332.

39.  Madiha Saeed, Zhiai Xu, Bruno G. De Geest, Huixiong Xu, Haijun Yu*, Molecular imaging for cancer immunotherapy: Seeing is believing. Bioconjugate Chemistry. (Review Article) 2020, 31, 404-415.

40.  Bo Hou#, Lei Zhou#, Hui Wang#, Madiha Saeed, Dangge Wang, Zhiai Xu, Yaping Li, Haijun Yu*. Engineering Stimuli-Activatable Boolean Logic Prodrug Nanoparticles for Combination Cancer Immunotherapy. Adv Mater, 2020. 1907210.

41.  Weiqi Wang, Yilan Jin, Xiao Liu, Sadia Z. Bajwa, Waheed S. Khan, Zhiai Xu, Haijun Yu,* Stimuli-activatable nanomedicine for chemodynamic therapy of cancer. WIREs Nanomedicine & Nanobiotechnology. 2020, e1614, 1-14.

42.  Ang Gao, Binfan Chen, Jing Gao, Fengqi Zhou, Madiha Saeed, Bo Hou, Yaping Li,* Haijun Yu,* Sheddable Prodrug Vesicles Combating Adaptive Immune Resistance for Improved Photodynamic Immunotherapy of Cancer. Nano Letters. 2020, 20, 353-362.

43.  Haijun Yu*, Bruno G. De Geest*, Nanomedicine and Cancer Immunotherapy. Acta Pharmacologica Sinica (Editorial) 2020, 41, 879-880.

44.  叶佳依, 高晶, 王当歌, 于海军*. 基于纳米递药系统的肿瘤免疫检查点联合治疗研究进展中国科学: 生命科学, 2020, 50: 1-11

45.  Huan Geng#, Mengxue Zhou#, Bin Li, Liang Liu, Xu Yang, Yinxian Wen, Haijun Yu, Hui Wang,* Jun Chen,* Liaobin Chen*, Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy sof orthotopic osteosarcoma. Chemical Engineering Journal, 2020(1):128103.

46.  Tao Sun, Guangping Zhang, Zhongyuan Guo, Qinjun Chen, Yujie Zhang, Yongchao Chu, Qin Guo, Chao Li, Wenxi Zhou, Yiwen Zhang, Peixin Liu, Hongyi Chen, Haijun Yu, Liping Jiang, Chen Jiang, Co-delivery of Cu(I) chelator and chemotherapeutics as a new strategy for tumor theranostic. Journal of Controlled Release 321 (2020) 483–496

47.  Qingxue Sun#, Xiangyang Bai# Alexandros Marios Sofias, Roy van der Meel, Eduardo Ruiz-Hernandez, Gert Storm, Wim E. Hennink, Bruno De Geest, Fabian Kiessling, Haijun Yu, Twan Lammers*, Yang Shi*. Cancer nanomedicine meets immunotherapy: Opportunities and challenges. Acta Pharmacologica Sinica. 2020,41(7):954-958.

48.  Ayesha Shaheen, Ayesha Taj,Peter A Lieberzeit, Adnan Mujahid, Sadaf Hameed, Haijun Yu, Arshad Mahmood, Thomas J Webster, M. Hamid Rashid, Waheed S Khan*, Sadia Bajwa*. Design of heterostructured hybrids comprising ultrathin 2D bismuth tungstate nanosheets reinforced by chloramphenicol imprinted polymers used as biomimetic interfaces for mass-sensitive detection. Colloids and Surfaces B: Biointerfaces. 2020, 188, 110775.

 2019

49.  Bing Feng,# Zifei Niu,# Bo Hou,# Lei Zhou, Yaping Li,* Haijun Yu*. Enhancing Triple Negative Breast Cancer Immunotherapy by ICG-Templated Self-Assembly of Paclitaxel Nanoparticles. Adv Funct Mater, 2019. 1906605. 

50.  Zhihao Zhao#, Weiqi Wang#, Chenxi Li, Yiqiu Zhang, Tianrong Yu, Renfei Wu, Jiayue Zhao, Zhuang Liu, Jian Liu*, Haijun Yu*. Reactive Oxygen Species-Activatable Liposomes (RALP) Regulating Tumor Microenvironment for Photo/Chemo-Dynamic Therapy. Adv Funct Mater, 2019. 1905013.

51.  Madiha Saeed, Jing Gao, Yang Shi, Twan Lammers, Haijun Yu*. Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy. Theranostics (Review Article) 2019; 9: 7981-8000.

52.  Ang Gao, Xianli Hu, Madiha Saeed, Binfan Chen, Yaping Li, Haijun Yu,* Overview and recent advances in liposomal nanoparticle-based cancer immunotherapy. Acta Pharmacologica Sinica, 2019, 40, 1129-1137.

53.  Haijun Yu*, Rongqin Huang, Yu Nie, Synthetic nucleic acid nanomedicines: a Chinese perspective (Editorial). The Journal of Gene Medicine. 2019, 21, e3111.

54.  Weiqi Wang, Madiha Saeed, Yao Zhou, Lili Yang, Dangge Wang, Haijun Yu*, Non-viral gene delivery for cancer immunotherapy. The Journal of Gene Medicine. 2019, 21, e3092.

55.  Bing Feng,# Bo Hou,# Zhiai Xu, Madiha Saeed, Haijun Yu,* Yaping Li* Self-Amplified Drug Delivery with Light-Inducible Nanocargoes to Enhance Cancer Immunotherapy. Adv Mater, 2019, 1902960.

56.  Li Lei, Zhiai Xu*, Xianli Hu, Yi Lai, Jie Xu, Bo Hou, Ya Wang, Haijun Yu*, Yang Tian, Wen Zhang*. Bioinspired Multivalent Peptide Nanotubes for Sialic Acid Targeting and Imaging-Guided Treatment of Metastatic Melanoma. Small. 2019,1900157.

57.  Fangyuan Zhou,# Bing Feng,# Haijun Yu,* Dangge Wang, Tingting Wang, Yuting Ma, Siling Wang, Yaping Li*, Tumor Microenvironment-Activatable Prodrug Vesicles for Nano-enabled Cancer Immunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade. Adv Mater. 2019, 1805888.

58.  Dangge Wang, Tingting Wang, Haijun Yu,* Bing Feng, Lei Zhou, Fangyuan Zhou, Bo Hou, Hanwu Zhang, Min Luo, Yaping Li*. Engineering nanoparticles to locally activate T cells in the tumor microenvironment. Science Immunology 2019, 4, aau6584.

59.  HOU Bo, WANG Dang-ge, GAO Jing, WANG Hui*, LI Ya-ping, YU Hai-jun* Advances of microenvironment-activated nanosized drug delivery system for cancer immunotherapy. Acta Pharmaceutica Sinica, 2019, 54(10): 1802-1809.

60.  Jing Gao, Wei-qi Wang, Hai-jun Yu*. Acid-activatable Polymeric Drug Delivery Systems for Cancer Therapy. Acta Polymerica Sinica. 2019 (11): 1156-1166

61.  Yi Lai, Zhiai Xu,* Li Lei, Xianli Hu, Lingling Li, Liang Dong, Haijun Yu, Wen Zhang,* Peptide Nanotube-Templated Biomineralization of Cu2-xS Nanoparticles for Combination Treatment of the Metastatic Tumors. Small, 2019, 1904397.

62.  Ding, Chunyong; Wang, Fengyang; Dang, Yijing; Xu, Zhiai*; Li, Lingling; Yu, Haijun; Luo, Yi; Huang, Ruimin; Zhang, Ao; Zhang, Wen*. Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity. Analytical Chemistry, 2019, 91, 15577-15584.

63.  Chong li, Yiguang Wang*, Huile Gao, Gang Wei, Yongzhuo Huang, Haijun Yu, Yong Gan, Yongjun Wang, Lin Mei, Huanbing Chen, Haiyan Hu, Zhiping zhang, Yiguang Jin, Jian-Cheng Wang. Recent Progress in Research of Drug Delivery. Acta Pharmaceutica Sinica B, 2019, 9, 1145-1162.

 2018

64.  于海军*,王当歌,杨祥良,李亚平。纳米技术在抗肿瘤药物靶向递释系统中的研究现状«科技导报»“纳米生物医学专刊”2018, 36(22)108-117.

65.  Tingting Wang#, Dangge Wang#, Haijun Yu*, Bing Feng, Fangyuan Zhou, Lei Zhou, Hanwu Zhang, Shi Jiao, Yaping Li*. A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors. Nat Commun, 2018,9:1532.  

66.  Fengyang Wang, Shujuan Yu, Zhiai Xu*, Lingling Li, Yijing Dang, Xiaowei Xu, Yi Luo, Zhen Cheng, Haijun Yu, Wen Zhang, Ao Zhang, Chunyong Ding*. Acid-Promoted D-A-D Type Far-Red Fluorescent Probe with High Photostability for Lysosomal Nitric Oxide Imaging. Analytical Chemistry. 2018, 90, 7953-7962.

 2017

67.   Fangyuan Zhou#, Bing Feng#, Tingting Wang, Dangge Wang, Zhirui Cui, Siling Wang,* Chunyong Ding, Zhiwen Zhang, Jian Liu, Haijun Yu,* and Yaping Li* Theranostic Prodrug Vesicles for Reactive Oxygen Species-Triggered Ultrafast Drug Release and Local-Regional Therapy of Metastatic Triple-Negative Breast Cancer. Adv. Funct. Mater. 2017, 1703674. (Front cover).

68.   Jianping Liu, Tingting Wang, Dangge Wang, Anjie Dong*, Yaping Li, Haijun Yu*, Smart Nanoparticles for Therapy of the Drug-Resistant Tumors by Overcoming the Pathophysiological Barriers. Acta Pharmacologica Sinica (Review Article). 2017, 38, 1-8.

69.  Tingting Wang, Dangge Wang, Jianping Liu, Bing Feng, Fangyuan Zhou, Hanwu Zhang, Lei Zhou, Qi Yin, Haijun Yu*, Yaping Li*. Acidity-Triggered Ligand-Presenting Nanoparticles To Overcome Sequential Drug Delivery Barriers to Tumors. Nano Letters. 2017, 17, 5429-5436.

70.  Fangyuan Zhou#, Bing Feng#, Tingting Wang, Qingshuo Meng, Dangge Wang, Jianfeng Zeng, Zhiwen Zhang, Siling Wang, Haijun Yu*, Yaping Li*. Programmed Multi-Responsive Vesicles for Enhanced Tumor Penetration and Combination Therapy of Triple-Negative Breast Cancer. Adv. Funct. Mater. 2017, 27, 1606530. (Inside cover).

71.  Qiang Feng#, Jianping Liu#, Xuanyu Li, Jiashu Sun,* Xinghua Shi, Haijun Yu,* Yaping Li, and Xingyu Jiang* One-Step Microfluidic Synthesis of Nanocomplex with Tunable Rigidity and Acid-Switchable Surface Charge for Overcoming Drug Resistance. Small. 2017, 13:1603109. (Back cover).

72.  Chunhua Hu, Xiaoyu Liu, Wei Ran, Jia Meng, Yihui Zhai, Pengcheng Zhang*, Qi Yin, Haijun Yu, Zhiwen Zhang, Yaping Li*. Regulating cancer associated fibroblasts with losartan-loaded injectable peptide hydrogel to potentiate chemotherapy in inhibiting growth and lung metastasis of triple negative breast cancer. Biomaterials, 2017, 144, 60-72.

73.  Yihui Zhai, Jinghan Su, Wei Ran, Pengcheng Zhang*, Qi Yin, Zhiwen Zhang, Haijun Yu, Yaping Li*. Preparation and Application of Cell Membrane-Camouflaged Nanoparticles for Cancer Therapy. Theranostics. 2017, 7, 2575-2592.

74.  Jieying Yin, Tianqun Lang, Dongmei Cun, Zhong Zheng, Yan Huang, Qi Yin*, Haijun Yu, Yaping Li*. pH-sensitive Nano-complexes Overcome Drug Resistance and Inhibit Metastasis of Breast Cancer by Silencing Akt Expression. Theranostics. 2017, 7(17):4204-4216.

75.  He, Xinyu; Cao, Haiqiang; Wang, Hong; Tan, Tao; Yu, Haijun; Zhang, Pengcheng; Yin, Qi; Zhang, Zhiwen*; Li, Yaping*. Inflammatory Monocytes Loading Protease-Sensitive Nanoparticles Enable Lung Metastasis Targeting and Intelligent Drug Release for Anti-Metastasis Therapy. Nano Letters, 2017, 17, 5546–5554.

76.  Dong-Bing, Cheng, Guo-Bin Qi, Jing-Qi Wang, Yong Cong, Fu-Hua Liu, Haijun Yu, Zeng-Ying Qiao*, Hao Wang*. In Situ Monitoring Intracellular Structural Change of Nanovehicles through Photoacoustic Signals Based on Phenylboronate Linked RGD-Dextran/Purpurin 18 Conjugates. Biomacromolecules. 2017, 18, 1249–1258.

77.  Chongchong Feng, Fengyang Wang, Yijing Dan, Zhiai Xu*, Haijun Yu; Wen Zhang*. A Self-Assembled Ratiometric Polymeric Nanoprobe for Highly Selective Fluorescence Detection of Hydrogen Peroxide. Langmuir. 2017, 33: 328

78.  Haiqiang Cao, Lili Zou, Bin He, Lijuan Zeng, Yongzhuo Huang, Haijun Yu, Pengcheng Zhang, Qi Yin, Zhiwen Zhang*, Yaping Li*. Albumin Biomimetic Nanocorona Improves Tumor Targeting and Penetration for Synergistic Therapy of Metastatic Breast Cancer. Adv. Funct. Mater. 2017,1605679

79.  Shan Tang, Qingshuo Meng, Huiping Sun, Jinghan Su, Qi Yin*, Zhiwen Zhang, Haijun Yu, Lingli Chen, Wangwen Gu, Yaping Li*. Dual pH-Sensitive Micelles with Charge-Switch for Controlling Cellular Uptake and Drug Release to Treat Metastatic Breast Cancer. Biomaterials, 2017,114, 44-53.

 2016

80.  Dangge Wang,# Tingting Wang,# Jianping Liu, Haijun Yu,* Shi Jiao, Bing Feng, Fangyuan Zhou, Yuanlei Fu, Qi Yin, Pengcheng Zhang, Zhiwen Zhang, Zhaocai Zhou, Yaping Li,* Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy. Nano Letters, 2016, 16, 5503−5513.

81.  Tingting Wang#, Dangge Wang#, Haijun Yu*, Mingwei Wang, Jianping Liu, Bing Feng, Fangyuan Zhou, Qi Yin, Zhiwen Zhang, Yaping Li* Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/ Chemotherapy of the Drug Resistant Tumor. ACS Nano. 2016, 10, 3496−3508. ESI highly cited

82.  Fangyuan Zhou#, Bing Feng#, Haijun Yu*, Dangge Wang, Tingting Wang, Jianping Liu, Qingshuo Meng, Siling Wang*, Pengcheng Zhang, Zhiwen Zhang, Yaping Li*, Cisplatin Prodrug-Conjugated Gold Nanocluster: A Theranostic Platform for Treatment of Metastatic Breast Cancer. Theranostics. 2016, 6, 679-687.

83.  Lijuan Zeng#, Lili Zou#, Haijun Yu#, Xinyu He, Haiqiang Cao, Zhiwen Zhang,* Qi Yin, Pengcheng Zhang, Wangwen Gu, Lingli Chen, and Yaping Li. Treatment of Malignant Brain Tumor by Tumor-Triggered Programmed Wormlike Micelles with Precise Targeting and Deep Penetration. Adv. Funct. Mater. 2016, 26, 4201– 4212.

84.  Dangge Wang#, Tingting Wang#, Zhiai Xu, Haijun Yu*, Bing Feng, Junying Zhang, Chengyue Guo, Qi Yin, Zhiwen Zhang, Yaping Li* Cooperative Treatment of Metastatic Breast Cancer Using Host-Guest Nanoplatform Loading Docetaxel and siRNA. Small. 2016, 12, 488-498.

85.  Bing Feng, Fangyuan Zhou, Dangge Wang, Haijun Yu*, Yaping Li. Gold Nanomaterials for Treatment of Metastatic Cancer. Science China Chemistry. 2016, 59, 984–990.

86.  Haijun Yu*,#, Chengyue Guo#, Xianzhi Chen, Bing Feng, Jianping Liu, Tingting Wang, Dangge Wang, Zhirui Cui, Qi Yin, Zhiwen Zhang, Yaping Li* Triple-Layered pH-Responsive Micelleplexes Loaded with siRNA and Cisplatin Prodrug for NF-Kappa B Targeted Treatment of Metastatic Breast Cancer. Theranostic, 2016, 6, 14-27.

87.  Xinyu He#, Haijun Yu#, Xiaoyue Bao, Haiqiang Cao, Qi Yin, Zhiwen Zhang*, Yaping Li*. pH-Responsive Wormlike Micelles with Sequential Metastasis Targeting Inhibit Lung Metastasis of Breast Cancer. Adv Healthcare Mater 2016, 5, 439–448.

88.  Haijun Yu*, Yaping Li. pH and near-infrared light-responsive micelles with hyperthermia-triggered tumor penetration. Nanomedicine Nanotechnology Biology and Medicine. 2016,12, 461 (Abstract).

89.  Junying Zhang#, Jianping Liu#, Zhiai Xu,* Yingying Zhu, Tingting Wang, Linlin Lu, Jie Xu, Haijun Yu, Wen Zhang,* Photodynamic micelles for amyloid β degradation and aggregation inhibition. Chem Comm. 2016, 52:12044-12047.

90.  Hui-ping SUN, Jing-han SU, Qing-shuo MENG, Qi YIN, Zhi-wen ZHANG, Hai-jun YU, Peng-cheng ZHANG, Si-ling WANG*, Ya-ping LI.* Silibinin and indocyanine green-loaded nanoparticles inhibit the growth and metastasis of mammalian breast cancer cells in vitro. Acta Pharmacologica Sinica 2016, 37, 1–9.

91.  Huiping Sun, Jinghan Su, Qingshuo Meng, Qi Yin, Lingli Chen, Wangwen Gu, Zhiwen Zhang, Haijun Yu, Siling Wang, Yaping Li*. Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors. Adv. Mater. 2016, 28, 9581-9588.  

92.  Jinghan Su, Huiping Sun, Qingshuo Meng, Qi Yin, Pengcheng Zhang, Zhiwen Zhang, Haijun Yu, Yaping Li*. Bioinspired Nanoparticles with NIR-Controlled Drug Release for Synergetic Chemo-Photothermal Therapy of Metastatic Breast Cancer. Adv Funct Mater 2016, 26, 7495-7506. 

93.  Haiqiang Cao, Zhaoling Dan, Xinyu He, Zhiwen Zhang,* Haijun Yu, Qi Yin, Yaping Li.* Liposomes Coated with Isolated Macrophage Membrane Can Target Lung Metastasis of Breast Cancer. ACS Nano, 2016, 10, 7738-7748.

94.  Shan Tang, Qingshuo Meng, Huiping Sun, Jinghan Su, Qi Yin*, Zhiwen Zhang, Haijun Yu, Lingli Chen, Yi Chen, Wangwen Gu, Yaping Li*. Tumor-Microenvironment-Adaptive Nanoparticles Codeliver Paclitaxel and siRNA to Inhibit Growth and Lung Metastasis of Breast Cancer. Adv Funct Mater 2016, 26, 6033-6046.

95.  Jinghan Su, Huiping Sun, Qingshuo Meng, Qi Yin, Shan Tang, Zhiwen Zhang, Haijun Yu, Yaping Li*. Long Circulation RBC-Mimetic Nanoparticles with Peptide-Enhanced Tumor Penetration for Simultaneously Inhibiting Breast Tumor Growth and Lung Metastasis. Adv. Funct. Mater. 2016. 26, 1243-1252.

96.  Fengyang Wang, Qianqian Sun, Bing Feng, Zhiai Xu,* Junying Zhang, Jie Xu, Linlin Lu, Haijun Yu, Mingwei Wang, Yaping Li, Wen Zhang*. Polydopamine- Functionalized Graphene Oxide Loaded with Gold Nanostars and Doxorubicin for Combined Photothermal and Chemotherapy of Metastatic Breast Cancer. Adv. Healthcare Mater. 2016, 5, 2227-2236.

 2015

97.  Haijun Yu*,#, Zhirui Cui#, Pengcheng Yu#, Chengyue Guo, Bing Feng, Tongying Jiang, Siling Wang, Qi Yin, Dafang Zhong, Xiangliang Yang, Zhiwen Zhang, Yaping Li*. pH and near-infrared light-responsive micelles with hyperthermia-triggered tumor penetration and cytoplasm drug release reverse doxorubicin resistance in breast cancer. Adv Funct Mater 2015, 25, 2489-2500. (Front Cover)ESI highly cited

98.  Chongsheng Guo#, Haijun Yu#,*, Bing Feng, Weidong Gao, Mei Yan, Zhiwen Zhang, Yaping Li*, Shaoqing Liu*. Highly efficient ablation of metastatic breast cancer using ammonium-tungsten-bronze nanocube as a novel 1064 nm-laser-driven photothermal agent. Biomaterials. 2015, 52, 407-416.

99.Pengcheng Yu, Haijun Yu*, Chengyue Guo, Zhirui Cui, Xianzhi Chen, Qi Yin, Zhiwen Zhang, Xiangliang Yang, Yaping Li*. Reversal of Doxorubicin Resistance in Breast Cancer by Mitochondria-Targeted pH-Responsive Micelles. Acta Biomater 2015, 14,115-124.

100.Xinyu He, Xiaoyue Bao, Haiqiang Cao, Zhiwen Zhang,* Qi Yin, Wangwen Gu, Lingli Chen, Haijun Yu, and Yaping Li*. Tumor-Penetrating Nanotherapeutics Loading a Near-Infrared Probe Inhibit Growth and Metastasis of Breast Cancer. Adv. Funct. Mater. 2015, 25, 2831–2839 (Back Cover).

101.Ya Wang, Qianqian Sun, Linling Zhu, Junying Zhang, Fengyang Wang, Linlin Lu, Haijun Yu, Zhiai Xu*, Wen Zhang*. Triplex molecular beacons for sensitive recognition of melamine based on abasic-site containing DNA and fluorescent silver nanoclusters. Chem Comm. 2015, 51, 7958-7961.

102.Pengfei Xu, Qingshuo Meng, Huiping Sun, Qi Yin*, Haijun Yu, Zhiwen Zhang, Mi Cao, Yingyi Zhang, Yaping Li*. Shrapnel nanoparticles loading docetaxel inhibit metastasis and growth of breast cancer. Biomaterials 2015, 64, 10–20.

103.Huiping Sun, Qingshuo Meng, Shan Tang, Jinghan Su, Qi Yin, Lingli Chen, Wangwen Gu, Haijun Yu, Zhiwen Zhang, Siling Wang*, Yaping Li*. Inhibition of Breast Cancer Metastasis by Pluronic Copolymers with Moderate Hydrophilic–Lipophilic Balance. Mol. Pharmaceutics, 2015, 12, 3323–3331.

104.Qi Yin, Jianan Shen, Haijun Yu, Yongzhuo Huang, Zhiwen Zhang, Yaping Li* Bioreducible Micelles with Endosomal Buffering and Multidrug Resistance-Reversing Function Enhance Anti-Tumor Efficacy of Doxorubicin. J. Biomed. Nanotechnol. 2015, 11, 1764-1775.

105.Haiqiang Cao, Zhiwen Zhang*, Shuang Zhao, Xinyu He, Haijun Yu, Qi Yin, Zhiping Zhang, Wangwen Gu, Lingli Chen, Yaping Li*. Hydrophobic interaction mediating self-assembled nanoparticles of succinobucol suppress lung metastasis of breast cancer by inhibition of VCAM-1 expression. J Control Release 2015, 205:162-171.

106.Haiqiang Cao#, Yixin Wang#, Xinyu He, Zhiwen Zhang*, Qi Yin, Yi Chen, Haijun Yu, Yongzhuo Huang, Lingli Chen, Minghua Xu, Wangwen Gu, Yaping Li*. Co-delivery of sorafenib and curcumin by directed self-assembled nanoparticles enhances therapeutic effect on hepatocellular carcinoma. Mol Pharmaceut 2015, 12, 922-931.

107.Shan Tang, Qi Yin*, Jinghan Su, Huiping Sun, Qingshuo Meng, Yi Chen, Lingli Chen, Yongzhuo Huang, Wangwen Gu, Minghua Xu, Haijun Yu, Zhiwen Zhang, Yaping Li*. Inhibition of metastasis and growth of breast cancer by pH-sensitive poly (β-amino ester) nanoparticles co-delivering two siRNA and paclitaxel. Biomaterials 2015, 48, 1-15.

 2014

108.Dangge Wang, Zhiai Xu, Haijun Yu*, Xianzhi Chen, Bing Feng, Zhirui Cui, Bin LinQi Yin, Zhiwen Zhang, Chunying Chen, Jun Wang, Wen Zhang, Yaping Li*. Treatment of metastatic breast cancer by combination of chemotherapy and photothermal ablation using doxorubicin-loaded DNA wrapped gold nanorods. Biomaterials. 2014, 35, 8374–8384. (20147-9月最高下载量TOP25)

109.Pengfei Xu, Haijun Yu, Zhiwen Zhang, Qingshuo Meng, Huiping Sun, Xianzhi Chen, Qi Yin, Yaping Li*. Hydrogen-bonded and reduction-responsive micelles loading atorvastatin for therapy of breast cancer metastasis. Biomaterials. 2014,35,7574-7587.

110.Shan Tang, Qi Yin, Zhiwen Zhang, Wangwen Gu, Lingli Chen, Haijun Yu, Yongzhuo Huang, Xianzhi Chen, Minghua Xu, Yaping Li* Co-delivery of doxorubicin and RNA using pH-sensitive poly (b-amino ester) nanoparticles for reversal of multidrug resistance of breast cancer. Biomaterials. 2014, 35, 6047-6059.

111.Zhiwen Zhang, Baohua Niu, Jian Chen, Xinyu He, Xiaoyue Bao, Jianhua Zhu, Haijun Yu, Yaping Li* The use of lipid-coated nanodiamond to improve bioavailability and efficacy of sorafenib in resisting metastasis of gastric cancer. Biomaterials. 2014, 35, 4565-4572.

112.Zhiwen Zhang, Haiqiang Cao, Shijun Jiang, Zeying Liu, Xinyu He, Haijun Yu, Yaping Li*. Nanoassembly of probucol enables novel therapeutic efficacy in the suppression of lung metastasis of breast cancer. Small 2014, 10, 4735-4745. 

113.Jisheng Xiao, Xiaopin Duan, Qingshuo Meng, Qi Yin, Zhiwen Zhang, Haijun Yu, Lingli Chen, Wangwen Gu, Yaping Li,* Effective delivery of p65 shRNA by optimized Tween 85-PEI conjugate for inhibition of tumor growth and lymphatic metastasis Acta Biomaterialia 2014, 10, 2674-83

114.Jianan Shen, Huiping Sun, Qingshuo Meng, Qi Yin, Zhiwen Zhang, Haijun Yu, Yaping Li* Simultaneous inhibition of tumor growth and angiogenesis for resistant hepatocellular carcinoma by co-delivery of sorafenib and survivin shRNA. Mol Pharmaceut 2014, 11, 3342-3351.

115.Xiaopin Duan, Jisheng Xiao, Qi Yin, Zhiwen Zhang, Haijun Yu, Shirui Mao, Yaping Li*. Multi-targeted inhibition of tumor growth and lung metastasis by redox-sensitive shell crosslinked micelles loading disulfiram. Nanotechnology 2014, 25, 125102.

116.Huihui Bu#, Xinyu He#, Zhiwen Zhang*, Qi Yin, Haijun Yu, Yaping Li*. A TPGS-incorporating nanoemulsion of paclitaxel circumvents drug resistance in breast cancer. Int J Pharm, 2014, 471, 206-213

117.Jianan Shen, Qingshuo Meng, Huiping Sui, Qi Yin, Zhiwen Zhang, Haijun Yu, and Yaping Li*. iRGD Conjugated TPGS Mediates Codelivery of Paclitaxel and Survivin shRNA for the Reversal of Lung Cancer Resistance. Molecular Pharmaceutics, 2014, 11, 2579-2591.

 2013

118.Haijun Yu, Zhiai Xu, Xianzhi Chen, Qi Yin, Zhiwen Zhang, Yaping Li,* Reversing Lung Cancer Multidrug Resistance Via Dual pH-Responsive Micelleplexes Mediated siRNA and Paclitaxel Co-Delivery. Macromolecular Bioscience. 2013, 14, 100–109. (Most Accessed article in 9/2013)

119.Haijun Yu, Zhiai Xu, Dangge Wang, Xianzhi Chen, Zhiwen Zhang, Yaping Li,* Intracellular pH-Activatable PEG-b-PDPA Wormlike Micelles for Hydrophobic Drug Delivery. Polymer Chem, 2013, 4, 5052-5055.

120.Chongshen Guo, Shu Yin*, Haijun Yu*, Shaoqin Liu*, Qiang Dong, Takehiro Goto, Zhiwen Zhang, Yaping Li*, Tsugio Sato. Photothermal Ablation Cancer Therapy using Homogeneous CsxWO3 Nanorods with Broad Near-Infra-Red Absorption. Nanoscale, 2013, 5, 6469-6478.

121.Zhiwen Zhang, Zeying Liu, Li Ma, Shijun Jiang, Yixin Wang, Haijun Yu*, Qi Yin, Jingbin Cui, Yaping Li*. Reversal of Multidrug Resistance by Mitochondrial Targeted Self-assembled Nanocarrier based on Stearylamine. Molecular Pharmaceutics, 2013, 10, 2426-2434.

122.Haijun Yu#, Junqiang Wang#,*, Xuetao Shi, Dmitri V. Louzguine-Luzgin, Hongkai Wu*, John H. Perepezko* Ductile Biodegradable Mg-based Metallic Glasses with Excellent Biocompatibility. Adv Funct Mater, 2013, 23, 4793–4800.

123.Haijun Yu+, Yonglong Zou+, Lei Jiang, Qi Yin, Xinyu He, Lingli Chen, Zhiwen Zhang, Wangwen Gu, Yaping Li.* Induction of Apoptosis in Non-Small Cell Lung Cancer by Downregulation of MDM2 Using pH-Responsive PMPC-b-PDPA/siRNA Complex Nanoparticles. Biomaterials, 2013, 34, 2738-2747.

124.Haijun Yu, Xuetao Shi, Pengcheng Yu, Jianhua Zhou, Zhiwen Zhang, Hongkai Wu*, Yaping Li*. Intracellular pH-responsive wormlike micelles for hydrophobic drug delivery. Journal of Controlled Release, 2013, 172, e33-34 (SIPCD 2012).

125.Jisheng Xiao, Xiaopin Duan, Qi Yin, Zhiwen Zhang, Haijun Yu,Yaping Li* Nanodiamonds-mediated doxorubicin nuclear delivery to inhibit lung metastasis of breast cancer. Biomaterials 2013, 34, 9648-9656.

126.Pengfei Xu, Qi Yin, Jianan Shen, Lingli Chen, Haijun Yu, Zhiwen Zhang, Yaping Li*. Synergistic Inhibition of Breast Cancer Metastasis by Silibinin-Loaded Lipid Nanoparticles Containing TPGS. International Journal of Pharmaceutics, 2013, 454, 21–30.

127.Jisheng Xiao, Xiaopin Duan, Qi Yin, Zehong Miao*, Haijun Yu, Chunying Chen, Zhiwen Zhang*, Jun Wang, Yaping Li*. The inhibition of metastasis and growth of breast cancer by blocking the NF-kB signaling pathway using bioreducible PEI-based/p65 shRNA complex nanoparticles. Biomaterials, 2013, 34, 5381-5390.

128.Xiaopin Duan, Jisheng Xiao, Qi Yin, Zhiwen Zhang, Haijun Yu, Shirui Mao, and Yaping Li*. Smart pH-Sensitive and Temporal-Controlled Polymeric Micelles for Effective Combination Therapy of Doxorubicin and Disulfiram. ACS Nano, 2013, 7, 5858-5869.

129.Qi Yin, Jianan Shen, Zhiwen Zhang, Haijun Yu, Lingli Chen, Wangwen Gu, and Yaping Li*. Multifunctional Nanoparticles Improve Therapeutic Effect for Breast Cancer by Simultaneously Antagonizing Multiple Mechanisms of Multidrug Resistance. Biomacromolecules, 2013, 14, 2242-2252.

130.Zhiwen Zhang, Fang Gao, Shijun Jiang, Lingli Chen, Zeying Liu, Haijun Yu, Yaping Li*. Bile salts enhance the intestinal absorption of lipophilic drug loaded lipid nanoparticles: mechanism and effect in rats. International Journal of Pharmaceutics, 2013, 444, 162-168.

131.Zhiwen Zhang, Li Ma, Shijun Jiang, Zeying Liu, Jian Huang, Lingli Chen, Haijun Yu, Yaping Li* A self-assembled nanocarrier loading teniposide improves the oral delivery and drug concentration in tumor. Journal of Controlled Release, 2013, 166, 30-37.

132.Qi Yin, Jianan Shen, Zhiwen Zhang, Haijun Yu, Yaping Li*. Reversal of multidrug resistant by stimuli-responsive drug delivery systems for therapy of tumor. Advanced Drug Delivery Review. 2013, 65, 1699–1715.

133.Zhiwen Zhang, Jian Huang, Shijun Jiang, Zeying Liu, Wangwen Gu, Haijun Yu, Yaping Li*. A high drug loading self-assembled nanoemulsion enhances the oral absorption of probucol in rats. Journal of Pharmaceutical Sciences. 2013, 102, 1301–1306.

134.Gang Huang, Huabing Chen, Ying Dong, Xiuquan Luo, Haijun Yu, Zachary Moore, Erik A. Bey, David A. Boothman, Jinming Gao* Superparamagnetic Iron Oxide Nanoparticles: Amplifying ROS Stress to Improve Anticancer Drug Efficacy. Theranostic, 2013, 3, 116-126.

135.Jianan Shen, Huiping Sun, Pengfei Xu, Qi Yin, Zhiwen Zhang, Siling Wang, Haijun Yu, Yaping Li*. Simultaneous inhibition of metastasis and growth of breast cancer by co-delivery of twist shRNA and paclitaxel using pluronic P85-PEI/TPGS complex nanoparticles. Biomaterials. 2013, 34, 1581-1590.

 2012

136.Xuetao Shi, Haijun Yu, Lei Li, Hongkai Wu*. One-step generation of covered porous PLGA microspheres for controlled delivery and regenerative medicine. Journal of Controlled Release. 2013, 172, e125. Abstract for Second Symposium on Innovative Polymers for Controlled Delivery, 2012. (SIPCD 2012)

137.Jianhua Zhou, Sung-Wook Choi, Haijun Yu, Younan Xia, Hongkai Wu*. Uniform protein microcapsules with semi-permeable, and enzyme-degradable walls for drug delivery applications. Journal of Controlled Release. 2013, 172, e98. Abstract for Second Symposium on Innovative Polymers for Controlled Delivery, 2012. (SIPCD 2012)

138.Xuetao Shi,* Song Chen, Jianhua Zhou, Haijun Yu, Lei Li, and Hongkai Wu* Directing Osteogenesis of Stem Cells with Drug-Laden, Polymer-Microsphere- Based Micropatterns Generated by Teflon Microfluidic Chips. Adv. Funct. Mater. 2012, 22, 3799-3807.

 2011

139.Haijun Yu, Yonglong Zou, Yiguang Wang, Xiaonan Huang, Gang Huang, Baran D. Sumer, David A. Boothman, Jinming Gao*. Overcoming Endosomal Barrier by Amphotericin B-loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery. ACS Nano, 2011, 5, 9246-9255.

140.Haijun Yu*, Yu Nie, Christian Dohmen, Yunqiu Li, Ernst Wagner. Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry. Biomacromolecules, 2011, 12, 2039-2047.

141.Haijun Yu, Chao Deng, Huayu Tian, Tiancheng Lu, Xuesi Chen, Xiabin Jing*. Chemo-Physical and Biological Evaluation of Poly(L-lysine) Grafted Chitosan Copolymers Used for Highly Efficient Gene Delivery. Macromol. Biosci. 2011, 10. 352-361.

142.Huiying Ding, Haijun Yu, Ying Dong, Ruhai Tian, Gang Huang, David A. Boothman, Baran D. Sumer, Jinming Gao*. Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia. Journal of Controlled Release, 2011, 156, 276-280.

 2009

143.            Haijun Yu*, Verena Russ, Ernst Wagner. Influence of the Molecular Weight of Bioreducible Oligoethylenimine Conjugates on the Polyplex Transfection Properties. AAPS Journal, 2009. June.

144.            Haijun Yu*, Ernst Wagner. Bioresponsive Polymers for Non-Viral Gene Delivery. Current Opinion in Molecular Therapeutics. (Review) 2009, 11, 165-178.

 2007

145.            Haijun Yu, Xuesi Chen, Tiancheng Lu, Chao Deng, Jing Sun, Huayu Tian, Peibiao Zhang, Xiabin Jing*. Synthesis and Characteration Polypepetide-Graft-Chitosan Copolymers Used for Gene Delivery. Biomacromolecules, 2007, 8, 1425-1435.

146.            Haijun Yu, Xiaoyi Xu, Xuesi Chen, Tiancheng Lu, Peibiao Zhang, Xiabin Jing*. Preparation and Antibacterial Effects of Silver Nanoparticles Containing PVA-PVP Hydrogels. Journal of Applied Polymer Science, 2007, 133, 125-133.

147.            Chao Deng, Xuesi Chen, Haijun Yu, Jing Sun, Tiancheng Lu, Xiabin Jing*. A Biodegradable Triblock Copolymer Poly (ethylene glycol)-b-Poly (L-lactide)-b-Poly(L-lysine): Synthesis, Self-assembly, and RGD Peptide Modification. Polymer, 2007, 48, 139-149.

148.            Jing Sun, Chao Deng, Xuesi Chen, Haijun Yu, Huayu Tian, Jingru Sun, and Xiabin Jing*. Self-Assembly of Triblock Copolymers containing Polypeptides in Aqueous Solutions and Its pH Dependence. Biomacromolecules, 2007, 8, 1013-1017.

149.            Jing Sun, Xuesi Chen, Chao Deng, Haijun Yu, Zhigang Xie, and Xiabin Jing*. Direct Formation of Giant Vesicles from Synthetic Polypeptides. Langmiur 2007, 23, 8308-8315. 

 2006

150.            Haijun Yu, Wenshou Wang, Xuesi Chen, Chao Deng, Xiabin Jing*. Synthesis and Characterization of the Biodegradable Polycaprolactone-graft-Chitosan Amphiphilic Copolymers. Biopolymers, 2006, 83, 233-242.

151.            Haijun Yu, Xiaoyi Xu, Xuesi Chen, Jingquan Hao, Xiabin Jing*. Medicated Wound Dressings Based on Poly (vinyl alcohol)/ Poly (N-vinyl pyrrolidone)/Chitosan Hydrogels. Journal of Applied Polymer Science 2006, 101, 2453-2463.

152.            Wenshou Wang, Peng Ping, Haijun Yu, Xuesi Chen, Xiabin Jing*. Synthesis and Characterization of a Novel Biodegradable Thermoplastic Polyurethane Elastomer. Journal of Polymer Science Part A: Polymer Chemistry, 2006, 44, 5505-5512.

153.            Xiaoyi Xu, Qingbiao Yang, Yongzhi Wang, Haijun Yu, Xuesi Chen, Xiabin Jing*. Biodegradable Electrospun Poly (L-lactide) Fibers Containing Antibacterial Silver Nanoparticles. European Polymer Journal, 2006, 42, 2081-2087.