https://orcid.org/0000-0003-3788-3575；https://scholar.google.com/citations?user=Odt96p4AAAAJ&hl=en

26 An enzyme-responsive double-locked amonafide prodrug for the treatment of glioblastoma with minimal side effects

Wei Cheng, Yanli Yang, Bo Zhang, Chen-Wen Shao, Wei Chen, Ruimin Xia, Wenwei Sun, Xiubo Zhao, Bing Zhang, Xiangjie Luo, Tony D. James, Yong Qian

Chem. Sci., 2024, Advance Article

DOI:10.1039/d4sc04555f

25 Mapping of β3-Adrenergic Receptor in Living Cells with a Ligand-Guided Fluores

Yani Liu, Xiangjie Luo, Wei Cheng, Ling Zhou, Yang Zhou, Hai-Liang Zhu, Tony D. James, Yong Qian

Anal. Chem. 2024, 96, 45, 18020–18028

DOI:10.1021/acs.analchem.4c03408

24 A two-photon fluorescent probe sensitive to NADPH reveals metabolic aberrations in brain cells arising from mitochondrial dysfunction in Alzheimer’s disease

Xueao Wang, Hai-Liang Zhu, Yani Liu,  Subin Kim, Chenrun Zhang , Zheng Li, Chen Xu，Hai-Liang Zhu，Yong Qian

Chemical Engineering Journal 495 (2024) 153652

DOI: 10.1016/j.cej.2024.153652

23 An antagonist-based two-photon fluorogenic probe for imaging metabotropic glutamate receptor 5 in neuronal cells

Mingran Si，Xinyi Cai，Yani Liu，Zheng Li，Xiangjie Luo，Hai-Liang Zhu，Yong Qian

Talanta，2024

DOI: 10.1016/j.talanta.2024.126167

22 Cascading Detection of Hydrogen Sulfide and N-Acetyltransferase 2 in Hepatocellular Carcinoma Cells Using a Two-Photon Fluorescent Probe

Yani Liu, Xueao Wang, Zheng Li, Liping Chen, Xinyi Cai, Zhigang Sun, Wei Cheng, Xiangjie Luo, Hai-Liang Zhu, and Yong Qian

Analytical Chemistry,2024

https://doi.org/10.1021/acs.analchem.4c00061

21 Activatable Dual-Optical Molecular Probe for Bioimaging Superoxide Anion in Epilepsy

Mingran Si, Li Lv, Yifan Shi, Zheng Li, Wenjing Zhai, Xiangjie Luo, Ling Zhang, Yong Qian

Analytical Chemistry,2024

https://doi.org/10.1021/acs.analchem.3c05641

20 Engineered human serum albumin for mapping drug fluctuations: Generatation of pseudo-fluorescent proteins by covalently coupling dyes for probing tamoxifen in vitro, in cellulo, and in vivo

Xueting Wang, Xianwen Wang, Rui Wang, Xueao Wang, Zheng Li, Yanli Yang, Hai-Liang Zhu,Yong Qian

Chemical Engineering Journal, 2024, 484, 149484.

DOI：10.1016/j.cej.2024.149484

19 A Near-Infrared Fluorogenic Probe for Rapid, Specific, and Ultrasensitive Detection of Sphingosine in Living Cells and In Vivo

Yanyan Chen, Tingting Hao, Jing Wang, Yiming Chen, Xiuxiu Wang, Wei Wei, Jing Zhao,Yong Qian

Advanced Science, 2024, 11, 2307598.

DOI: 10.1002/advs.202307598

18 A fluorescent prodrug to fight drug-resistant lung cancer cells via autophagy-driven ferroptosis.

 F.J. Chen, X.T. Wang, W. Chen, C.W. Shao, Yong Qian

Sensors and Actuators B: Chemical, 2024, 400, 134871.

https://doi.org/10.1016/j.snb.2023.134871

17 Novel 1,8-Naphthalimide Derivatives As Antitumor Agents and Potent Demethylase Inhibitors

Chao Ge, Lu Liu, Yanqing Wang, Xiaojiao Di, Xiangjie Luo, Hongke Liu, Yong Qian

ACS Medicinal Chemistry Letters, 2023, 14, 11, 1551–1557.

DOI:10.1021/acsmedchemlett.3c00353

16 3D dynamic tracking Aβ plaques in live brains using vinyl-bridged dyes with two-photon excitation/NIR emission and large Stokes shifts

Xueao Wang, Yani Liu, Xueting Wang, Xiaolian Ye, Wei Cheng, Guiquan Chen, Hai-Liang Zhu, Jing Zhao, Yong Qian

Biosensors and Bioelectronics, 2023, 238, 115563.

https://doi.org/10.1016/j.bios.2023.115563

15 Activity-Based Imaging of Macrophage Migration Inhibitory Factor with a Two-Photon Fluorescent Probe

Xueao Wang, Xueting Wang, Yani Liu, Zhigang Sun, Huan Liu, Jiawen Shen, Hai-Liang Zhu, and Yong Qian

ACS Sensors, 2023, 8, 1, 335–343.        
DOI:10.1021/acssensors.2c02326

                                                    

14 3D tracking of ferrous iron in the epileptic mouse brain and screening of iron homeostasis regulators with a two-photon fluorescent probe. 

Chenwen Shao, Zhang-Peng Chen, Chao Yan, Yong Qian 

STAR Protocols, 2022, 3,101522. 

https://doi.org/10.1016/j.xpro.2022.101522.

13  A high selective colorimetric fluorescent probe for detection of silver ions in vitro and in vivo and its application on test strips.

Yumeng Song, Xueting Wang, Huan Liu, Xueao Wang, Dongdong Li, Hai-Liang Zhu, Yong Qian 

Talanta, 2022, 246, 123366. 

 https://doi.org/10.1016/j.talanta.2022.123366

12 3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.

Chenwen Shao, Yani Liu, Zhangpeng Chen, Yajuan Qin, Xueao Wang, Xueting Wang, Chao Yan, Hai-Liang Zhu, Jing Zhao, Yong Qian 

Cell Chem. Biol. 2022, 29, 43-56.

https://doi.org/10.1016/j.chembiol.2021.12.006.

11 Biotinylated curcumin as a novel chemosensitizer enhances naphthalimide-induced autophagic cell death in breast cancer cells

Chenwen Shao, Jian Wu, Siqi Han, Yani Liu, Zhi Su, Hai-Liang Zhu, Hong-Ke Liu, Yong Qian 

Eur. J. Med. Chem. 2022, 222, 114029. 

https://doi.org/10.1016/j.ejmech.2021.114029 

10  In vivo brain imaging amyloid-β aggregates in Alzheimer’s disease by near-infrared fluorescence probe

Jian Wu, Chenwen Shao, Xiaolian Ye, Xiaojiao Di, Dongdong Li, Hu Zhao, Bing Zhang, Guiquan Chen, Hong-Ke Liu, Yong Qian 

ACS Sensors, 2021, 6, 3, 863–870.

DOI: 10.1021/acssensors.0c01914.

9 In vivo imaging macrophage migration inhibitory factor in liver cancer with an activity-based probe

Chenwen Shao, Christian Hedberg, Yong Qian 

Anal. Chem., 2021, 93, 2152–2159.

DOI: 10.1021/acs.analchem.0c03964.

8 Hydrogen sulfide triggered molecular agent for imaging and cancer therapy

Chao Ge, Xiaojiao Di, Siqi Han, Mengmeng Wang, Xiaoting Qian, Zhi Su, Hong-Ke Liu, Yong Qian 

Chem. Commun., 2021, 57, 1931-1934.

DOI: 10.1039/D0CC07982K.

 7 Monitoring hydrogen polysulfide during ferroptosis with a two-photon fluorescent probe

Xiaojiao Di, Chao Ge, Yani Liu, Chenwen Shao, Hai-Liang Zhu, Hong-Ke Liu, Yong Qian

Talanta, 2021, 232, 122467.

https://doi.org/10.1016/j.talanta.2021.122467

 6 A self-immolated fluorogenic agent triggered by H2S exhibiting potential anti-glioblastoma activity, Analyst

Chao Ge, Ji Li, Lu Liu, Hong-Ke Liu, Yong Qian

Analyst, 2021, 146, 3510-3515.

DOI: 10.1039/D1AN00457C.

5 In vivo Tracking Cystine/Glutamate Antiporter-Mediated Cysteine/Cystine Pool under Ferroptosis, Analytica Chimica Acta

Zhen Li, Yan Li, Yushun Yang, Zhiyuan Gong, Hailiang Zhu, Yong Qian 

Analytica Chimica Acta, 2020, 1125, 66-75.

DOI: 10.1016/j.aca.2020.05.049. 

4 Epileptic brain fluorescent imaging reveals apigenin can relieve the myeloperoxidase-mediated oxidative stress and inhibit ferroptosis

Chenwen Shao, Jiwen Yuan, Yani Liu, Yajuan Qin, Xueao Wang, Jin Gu, Guiquan Chen, Bing Zhang, Hong-Ke Liu, Jing Zhao, Hai-Liang Zhu, Yong Qian 

Proc. Natl. Acad. Sci. USA., 2020, 117 (19), 10155-10164.

DOI: 10.1073/pnas.1917946117.

3  Imaging of formaldehyde fluxes in epileptic brains with a two-photon fluorescence probe

Jian Chen, Chenwen Shao, Xueao Wang, Jin Gu, Hai-Liang Zhu, Yong Qian 

Chem. Commun., 2020, 56: 3871-3874.

DOI: 10.1039/D0CC00676A. 

2  Imaging Dynamic Peroxynitrite Fluxes in Epileptic Brains with a Near‐Infrared Fluorescent Probe

Jiong-Sheng Hu, Chenwen Shao, Xueao Wang, Xiaojiao Di, Xuling Xue, Zhi Su, Jing Zhao, Hai-Liang Zhu, Hong-Ke Liu, Yong Qian 

Adv. Sci., 2019, 6, 1900341.

DOI: 10.1002/advs.201900341.

1 Imaging dynamic changes of an intracellular cysteine pool that responds to the stimulation of external oxidative stress

Kun Chen, Meng Zhang, Yalin Qi, Jing Fan, Xiang Ma, Hailiang Zhu, Yong Qian 

Analyst, 2019, 144, 2320-2326.

DOI: 10.1039/C8AN02232A.