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成果及论文

   


                                              2011, 3 -至今(入职沈阳药科大学后)

1  Supramolecular Catalytic Synthesis of A Novel Bis(salicylaldehyde hydrazone) Ligand for  Ratiometric Recognition of AT-DNA

       Zhengning Shu, Yan Chen, Hui Yu, Xiaoyu Liao, Chuanfeng Liu, Haodong Tang, Sicong Li and Peng Yang*,

       Chem. Commun., 2019, DOI: 10.1039/C9CC01436E  (IF=6.29)

       https://pubs.rsc.org/en/content/articlelanding/2019/cc/c9cc01436e/unauth#!divAbstract

        


2     Supramolecular Recognition of Three Way Junctions DNA by a Cationic Calix[3]carbazole (Front Cover).

  ZhaozhengYang, Yan Chen, Gang Li, Zhangmin Tian, Liang Zhao, Xi Wu, Qi Ma, Mingzhe Liu, Peng Yang

  Chem.-Eur. J.,  2018, 24 (23), 6087  (IF= 5.16)

https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201705564


                      

3       Supramolecular Recognition of A-tracts DNA by Calix[4]carbazole.

Gang Li, Xiaoyu Song, Hui Yu, Chun Hu, Mingzhe Liu, Jie Cai, Liang Zhao,Yan Chen, Peng Yang

Sensor Actuat B-Chem, 2018,259,177    (IF=5.66)

https://www.sciencedirect.com/science/article/pii/S0925400517323596


                        

               

4     Engineering 1,3-Alternate Calixcarbazole for Recognition and Sensing of Bisphenol F in Water

 Gang Li, Liang Zhao, Peng Yang*, Zhaozheng Yang, Zhangmin Tian, Yan Chen, Hongyan Shen, Chun Hu*

       Anal. Chem., 2016, 88, 10751  (IF=6.32)

https://pubs.acs.org.ccindex.cn/doi/abs/10.1021/acs.analchem.6b03398


                   

 

5    A Switching Sensor of C-H Bond breakage/Formation Regulated by Mediating Copper(II)'s Complexation

      Xue Zhou,Gang Li, Peng Yang*, LiangZhao, Tuo Deng, Hongyan Shen, Zhaozheng Yang, Zhangmin Tian, Yan Chen.

      Sensor Actuat B-Chem, 2017, 242, 56  (IF=5.66)

https://www.sciencedirect.com/science/article/pii/S0925400516317609


    

6    Calix[3]carbazole: One-Step Synthesis and Host–Guest Binding

Peng Yang*, Yong Jian, Xue Zhou, Gang Li, Tuo Deng, Hongyan Shen, Zhaozheng Yang, Zhangmin Tian.

J. Org. Chem.,  2016, 81, 2974  (IF=4.84)

https://pubs.acs.org.ccindex.cn/doi/abs/10.1021/acs.joc.6b00252

           


7. Adenosine triphosphateselective fluorescent turn-on response of a novel thiazole orange derivative via their cooperative co-assembly

     Tuo Deng, JianHui Chen, Hui Yu, Peng Yang*, Yong Jian, Gang Li, Xue Zhou, Hongyan Shen, Jianzhou Gui*

   Sensor Actuat B-Chem, 2015, 209, 735. (IF= 4.75)

    https://www.sciencedirect.com/science/article/pii/S0925400514015500


         


8. Synthesis of a novel methylene-bridged biscarbazole derivative and evaluation of its DNA and nucleotide binding properties

    Gang Li, Xue Zhou, Peng Yang*, Yong Jian, Tuo Deng, Hongyan Shen, Ying Bao.

Tetrahedron Lett.,  201455, 7054. (IF= 2.39)

         https://www.sciencedirect.com/science/article/pii/S0040403914018528

       

                                   2011, 3 以前(博士、博士后期间工作

9.   Enhanced gene expression in epithelial cells transfected with amino acid-substituted gemini nanoparticles

     Peng Yang, Jagbir Singh, Shawn Wettig, Marianna Foldvari, Ronald Verrall, Ildiko Badea*. 

     Eur. J. Pharm. Biopharm., 2010, 75,  311 (IF=4.30)

     https://www.sciencedirect.com/science/article/abs/pii/S0939641110001074

                       

10. Engineering Bisquinolinium/Thiazole Orange Conjugates for Fluorescent Sensing of GQuadruplex DNA

      Peng Yang, Anne De Cian, Marie-Paule Teulade-Fichou,* Jean-Louis Mergny*, David Monchaud.

      Angew. Chem. Int. Ed., 2009, 48, 2188  (IF=11.82)

     https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.200805613

                                         

11A MetalMediated Conformational Switch Controls G-Quadruplex Binding Affinity

        David Monchaud, Peng Yang, Laurent Lacroix, Marie-Paule Teulade-Fichou, Jean-Louis Mergny*.

       Angew. Chem. Int. Ed.,  2008, 47 , 4858  (IF= 10.87)

       https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.200800468


                                   

12.  Naphthalimide intercalators with chiral amino side chains: Effects of chirality on DNA binding, photodamage and antitumor cytotoxicity

        Qing Yang*, Peng Yang, Xuhong Qian*, Lianpeng Tong.

       Bioorg. & Med. Chem. Lett., 2008, 18, 6210    (IF=2.53)

         https://www.sciencedirect.com/science/article/pii/S0960894X08011761


                           

13. Isoquino [4, 5-bc] acridines: Design, synthesis and evaluation of DNA binding, anti-tumor and DNA photo-damaging ability

        Peng Yang, Qing Yang, Xuhong Qian*, Lianpeng Tong, Xiaolian Li.

        J.Photochem Photobio B-Biology.,  2006, 84, 221  (IF=2.96)

        https://www.sciencedirect.com/science/article/pii/S1011134406000820

         

14. Novel DNA bis-intercalators of isoquinolino [4, 5-bc] acridines: design, synthesis and evaluation of cytotoxic activity

      Peng Yang, Qing Yang and Xuhong Qian*.

      Tetrahedron 2005, 61, 11895    (IF=2.64)

        https://www.sciencedirect.com/science/article/pii/S0040402005016571


                               

15 Novel synthetic isoquinolino [5, 4-ab] phenazines: Inhibition toward topoisomerase I, antitumor and DNA photo-cleaving activities

  Peng Yang, Qing Yang, Xuhong Qian*, Jingnan Cui.

  Bioorg. & Med. Chem.,  2005, 13, 5909   (IF=2.79)

https://www.sciencedirect.com/science/article/pii/S0968089605006425

                   

专利

1.     二苯甲烷-4,4’-二酰腙类化合物及其应用. CN 201811041803.6

2.     咔唑二聚体衍生物及其制备方法与应用. CN 201810067167.8

3.     [n]咔唑衍生物及其作为T交叉DNA荧光分子探针的应用. CN 201711220558.0

4.     咔唑杯芳烃四环衍生物及其制备方法和应用. CN 201610615586.1

5.   新型环状寡聚咔唑衍生物及其制备方法与应用. ZL201510309211.8 (PCT/CN2015/099716)

6.     噻唑橙衍生物及其制备和作为双螺旋核酸荧光分子探针的应用. ZL201310595094.7

7.     一种以亚铜二甲硫醚配合物催化合成1,3-苯二胺衍生物的方法. ZL201210402282.9

8.     新型杂环并萘酰亚胺及双链化合物及其在肿瘤细胞中应用. ZL200510026784.6(第二发明人)

9.   Drug Delivery Agents Comprising Cyclodextrin Covalently Linked To A Gemini Surfactant And Pharmaceutical  

    Compositions Comprising The Same. (PCT/CA2012/000483;US9,168,306B2)(第三发明人)