2024
36. A Bicyclic Dioxetane Chemiluminescence Nanoprobe for Peroxynitrite Imaging In Vivo
Shi Min, Zhang Yun, Chen Jia-Xing, Wu Yanyuan, Wang zongping, Shi Pengfei,* Jin Xudong,* Wang Xue-Qiang*
Analytical Chemistry, 2024, 96, 19109–19116.
35. Development of Polymeric Aptamer Probes for In Vivo Continuous Precision Cancer Targeting
Silin Huang,† Yu-Ting He,† Xiao-Jing Zhang,† Xue-Qiang Wang* and Qiang Guo*
Materials Chemistry Frontiers, 2024, online.
34. DNA-Compatible Photoredox Atom Transfer Radical Addition to Alkynes with Thiosulfonates
Cong Wang, Yinghui Lu, Zhiyuan Peng, Chi Zhang, Qingchao Liu*, Xue-Qiang Wang*, Tiezheng Jia*
CCS Chemistry, 2024, online
Link: https://doi.org/10.31635/ccschem.024.202404703
33. Aptamer Glue-Catalysis Enables Hyperefficient Targeted Membrane Protein Degradation
Guo-Rong Zhang, Chi Zhang, Ting Fu, Weihong Tan, and Xue-Qiang Wang*
JACS Au, 2024, 4, 2907–2914.
Link: https://doi.org/10.1021/jacsau.4c00260
32. Polyfluoroalkyl Tag Decoration Enables Significantly Enhanced Tumor Penetration Ability of a PTK7 Targeting Aptamer
Yingying Li, Chi Zhang, Ting Fu, Xue-Qiang Wang*, Weihong Tan*
Bioconjugate Chemistry, 2024, 35, 674–681.
Link: https://doi.org/10.1021/acs.bioconjchem.4c00131
31. Ni-Catalyzed Csp2- and Csp3-Coupling for Divergent Bisboronic Ester Synthesis
Yue Cui, Shi-Tang Xu, Cheng-Yu Long, Shen-Huan Li, Jie Shen, Ting Fu, Xin-Hua Xu*, and Xue-Qiang Wang*
Organic Letters, 2024, 26, 3401–3406.
Link: https://doi.org/10.1021/acs.orglett.4c00904
30. High Contrast Bioimaging of Tumor & Inflammation with A Bicyclic Dioxetane Chemiluminescent Probe
Shang, Qian; Li, Shen-Huan; He, Yu-Ting; Zhang, Yun; Fu, Ting; Han, Shisong; Huang, Wenshan; Wang, Xue-Qiang*; Xu, Jie-Hua*
Analytical Chemistry, 2024, 96, 2286–2291. DOI: 10.1021/acs.analchem.3c05062
Link: https://doi.org/10.1021/acs.analchem.3c05062
2023
29. Emission Wavelength-Tunable Bicyclic Dioxetane Chemiluminescent Probes for Precise in vitro and in vivo Imaging
Li, Shen-Huan; Zhang, Guo-Rong; He, Yu-Ting; Yang, Liu; Li, Han-Lu; Long, Cheng-Yu; Cui, Yue; Wang, Xue-Qiang*
Analytical Chemistry, 2023, 95, 13191–13200.
Link: https://doi.org/10.1021/acs.analchem.3c02126
28. Chemical Tailoring of Aptamer Glues with Significantly Enhanced Recognition Ability for Targeted Membrane Protein Degradation
Zhang, Guo-Rong; Tan, Weihong; Wang, Xue-Qiang*
ACS Nano, 2023, 17, 15146-15154. DOI: 10.1021/acsnano.3c04457
Link: https://pubs.acs.org/doi/full/10.1021/acsnano.3c04457
27. Ni-Catalyzed Protecting Group-Free Diphenic Acid Analogs Synthesis
Bo-Wei Zhao, Liu Yang, Cheng-Yu Long,Han-Lu Li, Yu-Ting He, Xue-Qiang Wang*
Organic Letters, 2023, 25, 4700–4704. DOI：10.1021/acs.orglett.3c01625
Link：https://doi.org/10.1021/acs.orglett.3c01625
26. Regulating the Properties of XQ-2d for Targeted Therapeutic Agents Delivery to Pancreatic Cancer
Qiuxia Yang, Yongbo Peng, Zhengyu Deng, Dailiang Zhang, Cheng-Yu Long, Guo-Rong Zhang, Juan Li, Xue-Qiang Wang*, Weihong Tan*
National Science Review, 2023, 10, nwad113. DOI:10.1093/nsr/nwad113
Link: https://doi.org/10.1093/nsr/nwad113
25. A Versatile Strategy for Convenient Circular Bivalent Functional Nucleic Acids Construction
Xiao-Jing Zhang, Zhuo Zhao, Xia Wang, Min-Hui Su, Yingying Li, Quan Yuan, Xue-Qiang Wang*, Weihong Tan
National Science Review, 2023, 10, nwac107
Link：https://academic.oup.com/nsr/article/10/2/nwac107/6603820
2022：
24. Dual-Targeting Circular Aptamer Strategy Enabled Recognition of Dfferent Leukemia Cells with Enhanced Binding Ability
Lili Ai#, Tianhuan Peng#, Yingying Li, Hailan Kuai, Yingyu Sima, Minhui Su, Dan Wang, Qiuxia Yang, Xue-Qiang Wang*, Weihong Tan*
Angew. Chem. Int. Ed, 2022, 61, e202109500. DOI: 10.1002/anie.202109500
Link：https://doi.org/10.1002/anie.202109500
23. CsOH-Promoted Regiospecific C-H Chalcogenation of Indoles in H2O
Shitang Xu, Rongnan Yi, Chunling Zeng, Yue Cui, Xue-Qiang Wang*, Xinhua Xua, Ningbo Li*
Synlett, 2022, accepted, DOI: 10.1055/a-1879-2521 (invited letter)
Link：https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1879-2521
22. Highly Chemoselective Ni-Catalyzed Protecting-Group-Free 2,2'-Biphenols Synthesis and Mechanistic Insights
Cheng-Yu Long, Hao Chen, Cheng Ma, Bo-Wei Zhao, Shen-Huan Li, Yue Cui, Xinge Yang,*, Shao-Fei Ni*, Xue-Qiang Wang*
Organic Letters, 2022, 24, 4155–4159. DOI: 10.1021/acs.orglett.2c01367
Link： https://pubs.acs.org/doi/abs/10.1021/acs.orglett.2c01367
21. Molecularly Engineered Aptamers Targeting Tumor Tissue and Cancer Cells for Efficient in vivo Recognition and Enrichment
Xia Wang, Xiao-Jing Zhang, Yingying Li, Guo-Rong Zhang, Juan Li, Xue-Qiang Wang*, Weihong Tan
CCS Chemistry, 2022, 4, 2581–2587. DOI: 10.31635/ccschem.021.202101337
Link: https://doi.org/10.31635/ccschem.021.202101337
2021：
20. Recent Progresses in Amination Enabled by Transition-Metal-Free C(sp2)-O/C(sp2)-S Bond Cleavage Strategy
Shen-Huan Li, Cheng-Yu Long, Xin-Ge Yang*, Xue-Qiang Wang*
Synthesis 2021, 53, 3716. (Invited Review) DOI: 10.1055/s-0040-1720382
Link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0040-1720382
19. Regulating the Anticancer Efficacy of Sgc8-Combretastatin A4 Conjugates: A Case of Recognizing the Significance of Linker Chemistry for the Design of Aptamer-Based Targeted Drug Delivery Strategies
Zhiyong Huang, Dan Wang, Cheng-Yu Long, Shen-Huan Li, Xue-Qiang Wang*, Weihong Tan*
J. Am. Chem. Soc. 2021, 143, 8559–8564. DOI: 10.1021/jacs.1c03013
Link: https://pubs.acs.org/doi/10.1021/jacs.1c03013
18. A New Paradigm for Artesunate Anticancer Function： Considerably Enhancing the Cytotoxicity via Conjugating Artesunate with Aptamer
Li Yingying, Peng Yongbo, Tan Yan, Xuan Wenjing, Fu Ting, Xue-Qiang Wang*, Weihong Tan*
Signal Transduction and Targeted Therapy, 2021, 6, 327. DOI: 10.1038/s41392-021-00671-8
Link: https://www.nature.com/articles/s41392-021-00671-8
17. Aptamer-Peptide Conjugates as Targeted Chemosensitizers for Breast Cancer Treatment
Yan Tan, Yingying Li, Yi-Xin Qu, Yuanye Su, Yongbo Peng, Zilong Zhao, Ting Fu, Xue-Qiang Wang*, Weihong Tan*
ACS Applied Materials & Interfaces, 2021, 13, 8, 9436–9444. DOI: 10.1021/acsami.0c18282.
Link: https://pubs.acs.org/doi/abs/10.1021/acsami.0c18282
16. Nucleophilic Etherification of Heteroaryl Alkyl Ethers, Heteroaryl Halides with (Deuterated)Alcohols
Wang, Xia# Qu, Yixin# Long, Chengyu Wang, Xue-Qiang*
Chinese Journal of Organic Chemistry, 2021, 41, 2, 795-805. DOI: 10.6023/cjoc202006077.
Link: http://sioc-journal.cn/Jwk_yjhx/EN/10.6023/cjoc202006077
2020：
15. Hierarchical Fabrication of DNA Wireframe Nanoarchitectures for Efficient Cancer Imaging and Targeted Therapy
Dan Wang, Ruizi Peng, Yongbo Peng, Zhengyu Deng, Fengyuan Xu, Yuanye Su, Pengfei Wang, Ling Li, Xue-Qiang Wang*， Yonggang Ke*, Weihong Tan*
ACS Nano, 2020, 14, 17365–17375.
Link: https://pubs.acs.org/doi/abs/10.1021/acsnano.0c07495
14. Highly Chemoselective Access to 2,2'-Diaminobiaryls via Ni-Catalyzed Protecting-Group-Free Coupling of 2-Haloanilines
Cheng-Yu Long#, Shaofei Ni#, Min-Hui Su#, Xue-Qiang Wang*, Weihong Tan
ACS Catalysis, 2020, 10, 13641–13649
Link：https://pubs.acs.org/doi/10.1021/acscatal.0c03428
13. Modularly Engineered Solid‐Phase Synthesis of Aptamer‐Functionalized Small Molecule Drugs for Targeted Cancer Therapy
Dan Wang,# Yongbo Peng,# Zhengyu Deng,# Yan Tan, Yuanye Su, Hailan Kuai, Lili Ai, Zhiyong Huang, Xue-Qiang Wang*, Xiaobing Zhang*, and Weihong Tan*
Advanced Therapeutics, 2020, 202000074
Link: https://onlinelibrary.wiley.com/doi/abs/10.1002/adtp.202000074
12. Aptamer Enables Consistent Maytansine Delivery Through Maintaining Receptor Homeostasis for HER2 Targeted Cancer Therapy
Yan Tan, Yongbo Peng, Lili Ai, Yingying Li, Yixin Qu, Dan Wang, Yuanye Su, Tanggang Deng, Ting Fu, Zilong Zhao, Xue-Qiang Wang*, and Weihong Tan*
Bioconjugate Chem. 2020, 31, 7, 1766–1774
Link: https://pubs.acs.org/doi/abs/10.1021/acs.bioconjchem.0c00250
11. Targeted delivery of emodin to adipocytes by aptamer-functionalized PEG-PLGA nanoparticles in vitro
Bo Yu，Ying Pu，Jun Liu，Jie Liao，Ke Chen，Jiani Zhang，Wen Zhong，Yalan Hu，Xue-Qiang Wang*, Bo Liu*, Huixia Liu*, Weihong Tan
J. Drug Deliv. Sci. Technol., 2020, 57, DOI: 10.1016/j.jddst.2020.101739
Link: https://www.sciencedirect.com/science/article/pii/S1773224719319112
10. Conjugating Aptamer and Mitomycin C with Reductant-Responsive Linker Leading to Synergistically Enhanced Anticancer Effect
Qiuxia Yang, Zhengyu Deng, Dan Wang, Jiaxuan He, Dailiang Zhang, Yan Tan, Tianhuan Peng Xue-Qiang Wang*, Weihong Tan*
J. Am. Chem. Soc. 2020, 142, 2532-2540
Link: https://pubs.acs.org/doi/10.1021/jacs.9b12409
9. Molecularly Engineering Triptolide with Aptamers for High Specificity and Cytotoxicity for Triple-Negative Breast Cancer
Jiaxuan He, Tianhuan Peng, Yongbo Peng, Lili Ai, Zhengyu Deng, Xue-Qiang Wang*, Weihong Tan*
J. Am. Chem. Soc. 2020, 142, 6, 2699–2703
Link: https://pubs.acs.org/doi/10.1021/jacs.9b10510
8. Polymeric Engineering of Aptamer–Drug Conjugates for Targeted Cancer Therapy
Zhengyu Deng, Qiuxia Yang, Yongbo Peng, Jiaxuan He, Shujuan Xu, Dan Wang, Tianhuan Peng, Ruowen Wang, Xue-Qiang Wang*, Weihong Tan*
Bioconjugate Chem. 2020, 31, 37-42
Link: https://pubs.acs.org/doi/10.1021/acs.bioconjchem.9b00715
7. Functional nucleic acids for cancer theranostics
Tianhuan Peng, Zhengyu Deng, Jiaxuan He, Yingying Li, Yan Tan, Yongbo Peng, Xue-Qiang Wang*,Weihong Tan*
Coordination Chemistry Reviews, 2020, 43, 213080
Link: https://www.sciencedirect.com/science/article/pii/S0010854519304692
2019:
6. Deuterated Aryl Alkyl Ethers Synthesis via Nucleophilic Etherification of Aryl Alkyl Ethers and Thioethers with Deuterated Alcohols
Shuai Li, Xia Wang, Xinge Yang*, Guiquan Yu, Xue-Qiang Wang*
Synlett 2019, 30, 1805-1809
Link: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0037-1611898
5. Rapid Amination of Methoxy Pyridines with Aliphatic Amines
Xia Wang，Cheng-Yu Long，Min-Hui Su，Yi-Xin Qu，Shen-Huan Li，Xiao-Jing Zhang，Xue-Qiang Wang*
Org. Process Res. Dev. 2019，23，1587-1593 （Invited paper）
Link: https://pubs.acs.org/doi/10.1021/acs.oprd.9b00235
4. Anticancer-Active N-Heteroaryl Amines Syntheses: Nucleophilic Amination of N-Heteroaryl Alkyl Ethers with Amines
Xia Wang, Qiu-Xia Yang, Cheng-Yu Long, Yan Tan, Yi-Xin Qu, Min-Hui Su, Weihong Tan*, Xue-Qiang Wang*
Org. Lett. 2019, 21, 5111-5115
Link: https://pubs.acs.org/doi/full/10.1021/acs.orglett.9b01711
2018:
3. Nucleophilic Amination and Etherification of Aryl Alkyl Thioethers
Xia Wang, Yue Tang, Cheng-Yu Long, Wen-Ke Dong, Chenchen Li, Xinhua Xu, Wanxiang Zhao,* Xue-Qiang Wang*
Org. Lett. 2018, 20, 4749–4753. Highlighted by Synfacts 2018, 14(10), 1076
Link: https://pubs.acs.org/doi/10.1021/acs.orglett.8b01758
2. Metal-Free Etherification of Aryl Methyl Ether Derivatives by C-OMe Bond Cleavage
Xue-Qiang Wang,* Chenchen Li, Xia Wang, Qingli Wang, Xiu-Qin Dong, Abing Duan,* Wanxiang Zhao*
Org. Lett. 2018, 20, 4267–4272
Link: https://pubs.acs.org/doi/abs/10.1021/acs.orglett.8b01696
1. NaI-mediated Divergent Synthesis of Isatins and Isoindigoes: A New Protocol Enabled by Oxidation Relay Strategy
Hong-hua Zhang, Yong-qiang Wang, Long-tao Huang, Long-qing Zhu, Yi-yue Feng, Yingmei Lu, Quan-yi Zhao, Xue-Qiang Wang,* Zhen Wang *
Chem. Commun., 2018, 54, 8265-8268
Link: https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc04471f#!divAbstract
