144. Practical and modular cycloadditions of in-situ formed exocyclic vinylcarbenes. Cheng Zhang,* Shanliang Dong, Martin C. Dietl, Matthias Rudolph, Xinke Zhang, Kemiao Hong, Wei Yi, A. Stephen K. Hashmi,* and Xinfang Xu*, Chem Catal. 2025, 5, 101163.
143. Enantioselective Assembly of Fully Substituted α-Amino Allenoates Through a Mannich Addition and Stepwise [3,3]-σ Rearrangement Sequence. Haoxuan Yuan, Yi Zhou, Xiongda Xie, Ming Bao*, Kewei Chen, Kemiao Hong, Zhixiang Yu*, and Xinfang Xu*, Adv. Sci. 2024, 2409334.
142. Gold-Catalyzed Alkyne Oxidative Cyclization/Mannich-Type Addition Cascade Reaction of Ynamides with 1,3,5-Triazinanes. Kewei Chen, Chao Li, Shanliang Dong, Kemiao Hong, Jingjing Huang*, and Xinfang Xu*, J. Org. Chem. 2024, 89, 13623-13628.
141. Asymmetric difluoroalkylation via Michael addition of an in situ generated difluoroenol intermediate, Xiongda Xie, Gang Chen, Jingjing Huang,* Yongqiang Liu*, and Xinfang Xu*, Org. Chem. Front. 2024, 11, 4702-4707.
140. Enantioselective Construction of Quaternary Stereocenters via A Chiral Spiro Phosphoric Acid Assisted Formal Gold Carbene gem-Dialkylation Reaction. Kewei Chen, Su Zhou, Chao Li, Shanliang Dong, Kemiao Hong, and Xinfang Xu*, J. Am. Chem. Soc. 2024, 146, 19261–19270.
139. Catalytic [4+2]- and [4+4]-cycloaddition using furan-fused cyclobutanone as a privileged C4 synthon. Kemiao Hong, Mengting Liu, Lixin Qian, Ming Bao, Gang Chen, Xinyu Jiang, Jingjing Huang, and Xinfang Xu*, Nat. Commun. 2024, 15, 5407.
138. Blue Light-Induced Formal Insertion Reaction of α-Siloxy Carbene into C-H Bond of 1,3-Diketones. Jiang Xinyu, Zhang Xinke, Fang Xi, and Xinfang Xu*, Chinese J. Org. Chem. 2024, doi: 10.6023/cjoc202405026.
137. Catalytic (4+2) Annulation via Regio- and Enantioselective Interception of in-situ Generated Alkylgold Intermediate. Ming Bao, Yi Zhou, Haoxuan Yuan, Guizhi Dong, Chao Li, Xiongda Xie, Kewei Chen, Kemiao Hong, Zhi-Xiang Yu*, and Xinfang Xu*, Angew. Chem. Int. Ed. 2024, 63, e202401557.
136. Stepwise Carbene Transfer Reaction with Alkenes beyond Cyclopropanation. Minghan Yao, Shanliang Dong, Abdulla Yusuf and Xinfang Xu*, Synthesis 2024, 56, 2886-2898.
135. Asymmetric Carbene Transformations for the Construction of All-Carbon Quaternary Centers. MinghanYao, Shanliang Dong, and Xinfang Xu*, Chem. Eur. J. 2024, 30, e202304299.
134. Catalytic Asymmetric Difluoroalkylation Using In Situ Generated Difluoroenol Species as the Privileged Synthon. Xiongda Xie, Shanliang Dong, Kemiao Hong, Jingjing Huang, and Xinfang Xu*, Adv. Sci. 2024, 11, 2307520.
133. Catalytic 4-exo-dig carbocyclization for the construction of furan-fused cyclobutanones and synthetic applications. Kemiao Hong, Yi Zhou, Haoxuan Yuan, Zhijing Zhang, Jingjing Huang, Shanliang Dong, Wenhao Hu, Zhi-Xiang Yu*, and Xinfang Xu*, Nat. Commun. 2023, 14, 6378.
132. Construction of Chiral Quaternary Carbon Centers via Asymmetric Metal Carbene gem-Dialkylation. Shanliang Dong, Kemiao Hong, Zhijing Zhang, Jingjing Huang, Xiongda Xie, Haoxuan Yuan, Wenhao Hu, and XinfangXu*, Angew. Chem. Int. Ed. 2023, 62, e202302371
131. Yang Zheng, Jingxing Jiang, Yue Li, Yongliang Wei, Junqi Zhang, Jundie hu, Zhuofeng Ke,* Xinfang Xu,* and Liming Zhang,* Reactivities of α-Oxo BMIDA Gold Carbenes Generated by Gold-Catalyzed Oxidation of BMIDA-Terminated Alkynes. Angew. Chem. Int. Ed. 2023, 62, e202218175.
130. Cheng Zhang, Kemiao Hong, Shanliang Dong, Mengting Liu, Matthias Rudolph, Martin C. Dietl, Jian Yin, A. Stephen K. Hashmi,* and Xinfang Xu,* Generation and Utility of Cyclic Dienyl Gold Carbene Intermediates. ACS Catal. 2023, 13, 4646−4655.
129. Ming Bao, Xiongda Xie, Jingjing Huang, Michael Doyle, Zhi Ren, Haibo Yue, and Xinfang Xu*, Divergent Construction of N-Doped Polycyclic Aromatic Hydrocarbons with Indole as the Nitrogen Source Building Block. Chem. Eur. J. 2023, 29, e202300140
128. Mengting Liu, Xiongda Xie, Ming Bao, Zhijing Zhang, Wenhao Hu, Yu Qian and Xinfang Xu*, Gold-catalyzed carbocyclization and imidization of alkyne-tethered diazo compounds with nitrosoarenes for the synthesis of nitrones and naphthalene derivatives. Molecular Diversity 2023, 27, 1971–1978.
127. Weichen Xiong, Su Zhou, Xinke Zhang, Jingyu Zhao, Jingjing Huang, Wenhao Hu, and Xinfang Xu*, Gold-Catalyzed Alkyne Multifunctionalization through an Oxidation−Oxyalkylation−Aryloxylation Sequence. Org. Lett. 2023, 25, 405-409.
126. Haoxuan Yuan, Yinfeng Guo, Zhijing Zhang, Hongkai Sha, Yicheng He, Xinfang Xu* and Wenhao Hu,* A diastereoselective three-component reaction for the assembly of succinimide and isatin hybrid molecules with potent anticancer activities. Mol. Divers. 2023, 27, 837–843
125. Jingjing Huang, Yufei Chen, Yinfeng Guo, Ming Bao, Kemiao Hong, Yuanqing Zhang, Wenhao Hu, Jinping Lei,* Yongqiang Liu,* Xinfang Xu,* Synthesis of dihydrofuran-3-one and 9,10-phenanthrenequinone hybrid molecules and biological evaluation against colon cancer cells as selective Akt kinase inhibitors. Mol. Divers. 2023, 27, 845–855.
124. Kemiao Hong, Jingjing Huang, Minghan Yao, Xinfang Xu*, Recent Advances in Nitrene/Alkyne Metathesis Cascade Reaction. Chin. J. Org. Chem. 2022, 42, 344-352.
123. Xiongda Xie, Ming Bao, Kewei Chen, Xinfang Xu* and Wenhao Hu*, An asymmetric three-component reaction of a diazo compound with an alcohol and a seven-membered imine. Org. Chem. Front. 2022, 8, 2102-2108.
122. Xiangrong Liu, Xue Tian, Jiawu Huang, Yu Qian, Xinfang Xu, Zhenghui Kang*, and Wenhao Hu*, Enantioselective Propargylation of Oxonium Ylide with α-Propargylic-3-Indolymethanol: Access to Chiral Propargylic Indoles. Org. Lett. 2022, 24, 1027-1032.
121. Kemiao Hong, Jirong Shu, Shanliang Dong, Zhijing Zhang, Yicheng He, Mengting Liu, Jingjing Huang, Wenhao Hu*, and Xinfang Xu*, Asymmetric Three-Component Reaction of Enynal with Alcohol and Imine as An Expeditious Track to Afford Chiral α-Furyl-β-amino Carboxylate Derivatives. ACS Catal. 2022, 12, 14185–14193.
120. Kuiyong Dong,* Mengting Liu and Xinfang Xu,* Recent Advances in Catalytic Alkyne Transformation via Copper Carbene Intermediates. Molecules 2022, 27, 3088.
119. Hongkai Sha, Yu Qian,* Xiangji Yang, Kuiyong Dong, Xinfang Xu and Wenhao Hu*, A copper-catalyzed three-component reaction of dithioacetals with diazo ketones and ketimines. Org. Biomol. Chem. 2022, 20, 8223-8227.
118. Kemiao Hong, Xiangji Yang, Zhijing Zhang, Xiongda Xie, Xin Lv, Xinfang Xu* and Wenhao Hu,* Diastereoselective aldol-type interception of phenolic oxonium ylides for the direct assembly of 2,2-disubstituted dihydrobenzofurans. Org. Biomol. Chem. 2022, 20, 4635-4639
117. Ming Bao, Su Zhou, Wenhao Hu, and Xinfang Xu,* Recent advances in gold-complex and chiral organocatalyst cooperative catalysis for asymmetric alkyne functionalization. Chinese Chem. Lett. 2022, 33, 4969–4979.
116. Asymmetric Three-Component Reaction of Two Diazo Compounds and Hyrdroxylamine Derivatives for the Access to Chiral α‑Alkoxy-β-amino-carboxylates Xiangji Yang, Kemiao Hong, Sujie Zhang, Zhijing Zhang, Su Zhou, Jingjing Huang, Xinfang Xu,* and Wenhao Hu,* ACS Catal. 2022, 12, 12302−12309.
115. Zhenghui Kang, Wenju Chang, Xue Tian, Xiang Fu, Wenxuan Zhao, Xinfang Xu,* Yong Liang,* and Wenhao Hu*, Ternary Catalysis Enabled Three-Component Asymmetric Allylic Alkylation as a Concise Track to Chiral α,α-Disubstituted Ketones. J. Am. Chem. Soc. 2021, 143, 20818-20827.
114. Xue Tian, Xinfang Xu, Tongfei Jing, Zhenghui Kang*, Wenhao Hu*, Enantioselective Formal Carbene Insertion into C–N Bond of Aminal as A Concise Track to Chiral α-Amino-β2,2-amino Acids and Synthetic Applications. Green Syn. Catal. 2021, 2, 337-344.
113. Su Zhou, Xiongda Xie, Xinxin Xu, Shanliang Dong, Wenhao Hu and Xinfang Xu*, An Asymmetric Oxidative Cyclization/Mannich-type Addition Cascade Reaction for Direct Access to Chiral Pyrrolidin-3-ones. Chem. Commun. 2021, 57, 12171-12174.
112. Su Zhou, Yinwu Li, Xiangrong Liu, Wenhao Hu,* Zhuofeng Ke,* and Xinfang Xu,* Enantioselective Oxidative Multi-Functionalization of Terminal Alkynes with Nitrones and Alcohols for Expeditious Assembly of Chiral α‑Alkoxy-β-amino-ketones. J. Am. Chem. Soc. 2021, 143, 14703-14711.
111. Ming Bao, Xiongda Xie, Wenhao Hu* & Xinfang Xu*, Gold-Catalyzed Carbocyclization/C=N Bond Formation Cascade of Alkyne-Tethered Diazo Compounds with Benzo[c]isoxazoles for the Assembly of 4-Iminonaphthalenones and Indenes. Adv. Synth. Catal. 2021, 363, 4018-4023.
110. Cong Xu, Xiangrong Liu, Xiongda Xie, Lin Deng, Xinfang Xu, Albert S. C. Chan, Wenhao Hu,∗ A Rh(II)- or Ag(I)-Catalyzed Formal C–O Bond Insertion of Cyclic Hemiaminal with Aryl Diazoacetate. Synlett. 2021, 32, 1957-1962
109. Haoxuan Yuan, Kemiao Hong, Xiangrong Liu, Yu Qian, Xinfang Xu*, and Wenhao Hu*, Enantioselective Assembly of 3,3-Disubstituted Succinimides via Three-Component Reaction of Vinyl Diazosuccinimides with Alcohols and Imines. Chem. Commun. 2021, 57, 8043-8046.
108. Kuiyong Dong, Ahmad Humeidi, Wendell Griffith, Hadi Arman, Xinfang Xu*, and Michael P. Doyle*, Ag(I)-Catalyzed Reactions of Enol Diazoacetates and Imino Ethers: Synthesis of Highly Functionalized Pyrroles. Angew. Chem. Int. Ed. 2021, 60, 13394-13400.
107. Kemiao Hong, Shanliang Dong, Xinxin Xu, Zhijing Zhang, Taodao Shi, Haoxuan Yuan, Xinfang Xu*, and Wenhao Hu*, Enantioselective Intermolecular Mannich-type Interception of Phenolic Oxonium Ylide for the Direct Assembly of Chiral 2,2-Disubstituted Dihydrobenzofurans. ACS Catal. 2021, 11, 6750-6756.
106. Kuiyong Dong, Ahmad Humeidi, Wendell Griffith, Hadi Arman, Xinfang Xu*, and Michael P. Doyle*, Enantioselective Catalytic Cyclopropanation-Rearrangement Approach to Chiral Spiroketals. Org. Lett. 2021, 23, 3955-3959.
105. Kai Zhou, Ming Bao*, Hongkai Sha, Guizhi Dong, Kemiao Hong, Xinfang Xu, and Wenhao Hu*, Highly Diastereoselective Synthesis of Vicinal Diamines via Rh-Catalyzed Three-Component Reaction of Diazo Compounds with Diarylmethanimines and Ketimines. Org. Chem. Front. 2021, 8, 2997-3003.
104. Kuiyong Dong, Haifeng Zheng, Yongliang Su, Ahmad Humeidi, Hadi Arman, Xinfang Xu*, and Michael P. Doyle*, Catalyst-Directed Divergent Catalytic Approaches to Expand Structural and Functional Scaffold Diversity via Metallo-Enolcarbene Intermediates. ACS Catal. 2021, 11, 4712-4721.
103. Cheng Zhang, Kemiao Hong, Chao Pei, Su Zhou, Wenhao Hu, A. Stephen K. Hashmi*, and Xinfang Xu*, Gold(I)-Catalyzed Intramolecular Cyclization/ Intermolecular Cycloaddition Cascade as a Fast Track to Polycarbocycles and Mechanistic Insights. Nat. Commun. 2021, 12, 1182.
102. Ming Bao, Jinzhou Chen, Chao Pei, Sujie Zhang, Jinping Lei*, Wenhao Hu*, and Xinfang Xu*, Gold-Catalyzed Ketene Dual Functionalization and Mechanistic Insights: Divergent Synthesis of Indenes and Benzo[d]oxepines. Sci China Chem. 2021, 64, 778-787.
101. Su Zhou, Qianqian Liu, Ming Bao, Jie Huang*, Junjian Wang*, Wenhao Hu, and Xinfang Xu*, Gold(I)-Catalyzed Redox Transformation of o-Nitroalkynes with Indoles for the Synthesis of 2,3'-Biindole Derivatives. Org. Chem. Front. 2021, 8, 1808-1816.
100. Guizhi Dong, Ming Bao, Xiongda Xie, Shikun Jia, Wenhao Hu*, and Xinfang Xu*, Asymmetric Allylation by Chiral Organocatalyst-Promoted Formal Hetero-Ene Reactions of Alkylgold Intermediates. Angew. Chem. Int. Ed. 2021, 60, 1992-1999.
99. Xinxin Lv, Shuhao Liu, Su Zhou, Guizhi Dong, Dong Xing, Xinfang Xu*, and Wenhao Hu*, Asymmetric Three-Component Propargyloxylation for Direct Assembly of Polyfunctionalized Chiral Succinate Derivatives. CCS Chem. 2021, 3, 1903-1912.
98. Jinzhou Chen, Shuhao Liu, Xinxin Lv, Kemiao Hong, Jinping Lei, Xinfang Xu*, and Wenhao Hu*, Blue Light-Promoted Formal [4+1]-Annulation of Diazoacetates with o‑Aminoacetophenones: Synthesis of Polysubstituted Indolines and Computational Study. J. Org. Chem. 2020, 85, 13920-13928.
97. Shanliang Dong, Xiang Fu, and Xinfang Xu*, [3+2]‐Cycloaddition of Catalytically Generated Pyridinium Ylide: A General Access to Indolizine Derivatives. Asian J. Org. Chem. 2020, 9, 1133-1143.
96. Kuiyong Dong, Xinfang Xu*, and Michael P. Doyle*, Copper(I)-Catalyzed Highly Enantioselective [3+3]-Cycloaddition of γ-Alkyl Enoldiazoacetates with Nitrones. Org. Chem. Front. 2020, 7, 1653-1657.
95. Qian Zeng, Ciwang He, Su Zhou, Kuiyong Dong, Lihua Qiu*, and Xinfang Xu*, Dirhodium(II)-Catalyzed Cyclopropanation of Alkyne-Containing α-Diazoacetates for the Synthesis of Cycloalkynes. Adv. Synth. Catal. 2020, 362, 3137-3141.
94. Kemiao Hong, Su Zhou, Wenhao Hu*, and Xinfang Xu*, Rh-Catalyzed Nitrene Alkyne Metathesis/Formal C-N Bond Insertion Cascade: Synthesis of 3-Iminoindolines. Org. Chem. Front. 2020, 7, 1327-1333.
93. Yang Zheng, Ping Dai, Dafang Gao, Kemiao Hong, Luyao Kou, Shanliang Dong, Jundie Hu, Lihua Qiu, Wenhao Hu*, Xiaoguang Bao*, and Xinfang Xu*, Desaturation via Redox-Neutral Hydrogen Transfer Process: Synthesis of 2-Allyl Anilines, Mechanism and Applications. iScience. 2020, 23, 101168.
92. Dan Zhang, Xin Wang, Mengchu Zhang, Zhenghui Kang, Guolan Xiao, Xinfang Xu*, and Wenhao Hu*, Highly Enantioselective Trapping of Carboxylic Oxonium Ylides with Imines for Direct Assembly of Enantioenriched γ-Butenolides. CCS Chem. 2020, 2, 432-439.
91. Jingjing Huang, Han Su, Ming Bao, Lihua Qiu, Yuanqing Zhang*, and Xinfang Xu*, Gold(III)-Catalyzed Azide-yne Cyclization/O-H Insertion Cascade Reaction for the Expeditious Construction of 3-Alkoxy-4-quinolinone Frameworks. Org. Biomol. Chem. 2020, 18, 3888-3892.
90. Chaoqun Ao, Jingjing Huang, Xinfang Xu, Shikun Jia, Zhenghui Kang*, and Wenhao Hu*, A Rh-Catalyzed Three-Component Reaction for the Diastereoselective Synthesis of Pyrazolone Derivatives with Contiguous Quaternary Stereocenters. Org. Biomol. Chem. 2020, 18, 3466-3470.
89. Kuiyong Dong, Xing Fan, Chao Pei, Yang Zheng, Sailan Chang, Ju Cai, Lihua Qiu, Zhixiang Yu*, and Xinfang Xu*, Transient-Axial-Chirality Controlled Asymmetric Rhodium-Carbene C(sp2)-H Functionalization for the Synthesis of Chiral Fluorenes. Nat. Commun. 2020, 11, 2363.
88. Xiangrong Liu, Guolan Xiao, Xinfang Xu, Zhenghui Kang, Dan Zhang*, and Wenhao Hu*, A Cleavage‐Modification‐Reassembly Process Catalyzed by Rhodium and Brønsted Acid for the Synthesis of Multi‐Substituted Anilines. Adv. Synth. Catal. 2020, 362, 1961-1965.
87. Gopi Krishna Reddy Alavala, Niharika Pedireddi, Zhou Su, Jia Shi-Kun, Shi Taoda, Xinfang Xu, Qian Yu*, and Wenhao Hu*, Bronsted Acid Catalyzed Enantioselective Assembly of Spirochroman-3,3-oxindole. Org. Lett. 2020, 22, 2925-2930.
86. Xiaoyu Chen, Corentin Antoine Baratay, Maddison Elizabeth Mark, Xinfang Xu*, and Philip Wai Hong Chan*, Gold and Brønsted Acid Catalyzed Spirocyclization of 2- and 3-Indolyl-Tethered 1,4-Enyne Acetates to Spiro[4,n]alkyl[b]indoles. Org. Lett. 2020, 22, 2849-2853.
85. Shanliang Dong, Jingjing Huang, Hongkai Sha, Lihua Qiu, and Xinfang Xu*, Copper-Catalyzed Formal [1+2+2]-Annulation of Alkyne-Tethered Diazoacetates and Pyridines: Access to Polycyclic Indolizines. Org. Biomol. Chem. 2020, 18, 1926-1932.
84. Kai Zhou, Ming Bao, Jingjing Huang, Zhenghui Kang, Xinfang Xu, Wenhao Hu*, and Yu Qian*, Iron-Catalyzed [3 + 2]-Cycloaddition of in situ Generated N-Ylides with Alkynes or Olefins: Access to Multi-substituted/Polycyclic Pyrrole Derivatives. Org. Biomol. Chem. 2020, 18, 409-414.
83. Zhenghui Kang, Dan Zhang, Xinfang Xu*, and Wenhao Hu*, Privilege-Structure-Oriented Three-Component Asymmetric Aminomethylation: Assembly of Chiral 3-Aminomethyl Indolones. Org. Lett. 2019, 21, 9878-9883.
82. Chaoqun Ao, Xiaohan Yang, Shikun Jia, Xinfang Xu, Yanqiu Yuan, Dan Zhang*, and Wenhao Hu*, Zinc-Catalyzed Alkyne-Carbonyl Metathesis of Ynamides with Isatins: Stereoselective Access to Fully Substituted Alkenes. J. Org. Chem. 2019, 84, 15331-15342.
81. Taoda Shi, Changcheng Jing, Yu Qian, Xinfang Xu, Gopi Krishna Reddy Alavala, Xinxin Lv, and Wenhao Hu*, A Sustainable Catalytic Enantioselective Synthesis of Norstatine Derivatives. Org. Biomol. Chem. 2019, 17, 9792-9798.
80. Cheng Zhang, Kemiao Hong, Shanliang Dong, Chao Pei, Xiaolu Zhang, Ciwang He, Wenhao Hu*, and Xinfang Xu*, Gold(I)-Catalyzed Aromatization: Expeditious Synthesis of Polyfunctionalized Naphthalenes. iScience. 2019, 21, 499-508.
79. Qian Zeng, Kuiyong Dong, Chao Pei, Shanliang Dong, Wenhao Hu*, Lihua Qiu, and Xinfang Xu*, Divergent Construction of Macrocyclic Alkynes via Catalytic Metal-Carbene C(sp2)-H Insertion and the Buchner Reaction. ACS Catal. 2019, 9, 10773-10779.
78. Sripati Jana, Yang Zhen, Chao Pei, Xinfang Xu*, and Rene M. Koenigs*, Photochemical Ring Expansion Reactions: Synthesis of Tetrahydrofuran Derivatives and Mechanism Studies. Chem. Sci. 2019, 10, 10129-10134.
77. Xiaofang Zhao, Chao Song, Kemiao Hong, Xinfang Xu, Changyun Chen, Xianxu Chu, and Xiaoqing Zeng*, Spectroscopic Identification of Monomeric Methyl Metaphosphate. Dalton Trans. 2019, 48, 13907-13911.
76. Ciwang He, Ju Cai, Yang Zheng, Chao Pei, Lihua Qiu*, and Xinfang Xu*, Gold-Catalyzed Hydroalkoxylation/Povarov Reaction Cascade of Alkynols with N‑Aryl Imines: Synthesis of Tetrahydroquinolines. ACS Omega. 2019, 4, 15754-15763.
75. Kuiyong Dong, Kostiantyn O. Marichev, Xinfang Xu*, and Michael P. Doyle*, High Stereocontrol in the Preparation of Silyl-Protected-Substituted Enoldiazoacetates. Synlett. 2019, 30, 1457-1461.
74. Hanlin Wei, Su Zhou, Lihua Qiu, Yu Qian, Wenhao Hu, and Xinfang Xu*, Gold‐Catalyzed Dual Annulation of Homopropargyl Alcohols with Nitrones: Synthesis of Tetrahydropyrano[4,3‐b]indole Scaffolds. Adv. Synth. Catal. 2019, 361, 3569-3574.
73. Kuiyong Dong, Chao Pei, Qian Zeng, Lihua Qiu, Wenhao Hu, Yu Qian*, and Xinfang Xu*, Copper-Catalyzed [4+1]-Annulation of 2-Alkenylindoles with Diazoacetates: A Facile Access to Dihydrocyclopenta[b]indoles. Chem. Commun. 2019, 55, 6393-6396.
72. Han Su, Ming Bao, Wenhao Hu*, Lihua Qiu*, and Xinfang Xu, Gold-Catalyzed Dual Annulation of Azide-Tethered Alkynes with Nitriles: Expeditious Synthesis of Oxazolo[4,5-c]quinolines. Org. Chem. Front. 2019, 6, 2404-2409.
71. Kemiao Hong, Han Su, Chao Pei, Xinxin Lv, Wenhao Hu, Lihua Qiu*, and Xinfang Xu*, Rhodium-Catalyzed Nitrene/Alkyne Metathesis: An Enantioselective Process for the Synthesis of N-Heterocycles. Org. Lett. 2019, 21, 3328-3331.
70. Yang Zheng, Junqi Zhang, Xinpeng Cheng, Xinfang Xu*, and Liming Zhang*, The Wolff‐Rearrangement Reaction of Oxidatively Generated α‐Oxo Gold Carbenes: An Effective Approach to Silylketenes. Angew. Chem. Int. Ed. 2019, 58, 5241-5245.
69. Ming Bao, Xin Wang, Lihua Qiu, Wenhao Hu, Philip Wai Hong Chan*, and Xinfang Xu*, Gold-Catalyzed 1,2-Acyloxy Migration/Coupling Cascade of Propargyl Diazoacetates: Synthesis of Isomycin Derivatives. Org. Lett. 2019, 21, 1813-1817.
68. Cheng Zhang, Hongli Li, Chao Pei, Lihua Qiu, Wenhao Hu*, Xiaoguang Bao*, and Xinfang Xu*, Selective Vinylogous Reactivity of Carbene Intermediate in Gold-Catalyzed Alkyne Carbocyclization: Synthesis of Indenols. ACS Catal. 2019, 9, 2440-2447.
67. Qian Zeng, Kuiyong Dong, Jingjing Huang, Lihua Qiu*, and Xinfang Xu*, Copper-Catalyzed Carbene/Alkyne Metathesis Terminated with Buchner Reaction: Synthesis of Dihydrocyclohepta[b]indoles. Org. Biomol. Chem. 2019, 17, 2326-2330.
66. Xinxin Lv, Haijian Yang, Taoda Shi, Dong Xing, Xinfang Xu*, and Wenhao Hu*, Rhodium(II)-Catalyzed Formal [4+1]-Cycloaddition of Pyridotriazoles and Propargyl Alcohols: Synthesis of 2,5-Dihydrofurans. Adv. Synth. Catal. 2019, 361, 1265-1270.
65. Han Su, Ming Bao, Jingjing Huang, Lihua Qiu*, and Xinfang Xu*, Silver‐Catalyzed Carbocyclization of Azide‐Tethered Alkynes: Expeditious Synthesis of Polysubstituted Quinolines. Adv. Synth. Catal. 2019, 361, 826-831.
64. Ju Cai, Xin Wang, Yu Qian, Lihua Qiu, Wenhao Hu*, and Xinfang Xu*, Gold-Catalyzed Oxidative Cyclization/Aldol Addition of Homopropargyl Alcohols with Isatins. Org. Lett. 2019, 21, 369-372.
63. Zhenghui Kang, Yongheng Wang, Dan Zhang, Ruibo Wu, Xinfang Xu*, and Wenhao Hu*, Asymmetric Counter-Anion-Directed Aminomethylation: Synthesis of Chiral β-Amino Acids via Trapping of an Enol Intermediate. J. Am. Chem. Soc. 2019, 141, 1473-1478.
62. Chao Pei, Guang-Wei Rong, Zhi-Xiang Yu*, and Xinfang Xu*, Copper-Catalyzed Intramolecular Annulation of Conjugated Enynones to Substituted 1H-Indenes and Mechanistic Studies. J. Org. Chem. 2018, 83, 13243-13255.
61. Chao Pei, Cheng Zhang, Yu Qian*, and Xinfang Xu*, Catalytic Carbene/Alkyne Metathesis (CAM): a Versatile Strategy for the Alkyne Bifunctionalization. Org. Biomol. Chem. 2018, 16, 8677-8685.
60. Hanlin Wei, Ming Bao, Kuiyong Dong, Lihua Qiu, Bing Wu, Wenhao Hu*, and Xinfang Xu*, Enantioselective Oxidative Cyclization/Mannich Addition Enabled by Gold(I)/Chiral Phosphoric Acid Cooperative Catalysis. Angew. Chem. Int. Ed. 2018, 57, 17200-17204.
59. Xianxu Chu, Yang Yang, Bo Lu, Zhuang Wu, Weiyu Qian, Chao Song, Xinfang Xu, Manabu Abe, and Xiaoqing Zeng*, Methoxyphosphinidene and Isomeric Methylphosphinidene Oxide. J. Am. Chem. Soc. 2018, 140, 13604-13608.
58. Kuiyong Dong, Chao Pei, Qian Zeng, Hanlin Wei, Michael P. Doyle*, and Xinfang Xu*, Selective C(sp3)-H Bond Insertion in Carbene/Alkyne Metathesis Reactions. Enantioselective Construction of Dihydroindoles. ACS Catal. 2018, 8, 9543-9549.
57. Ming Bao, Yu Qian, Han Su, Bing Wu, Lihua Qiu, Wenhao Hu*, and Xinfang Xu*, Gold(I)-Catalyzed and H2O-Mediated Carbene Cascade Reaction of Propargyl Diazoacetates: Furan Synthesis and Mechanistic Insights. Org. Lett. 2018, 20, 5332-5335.
56. Cheng Zhang, Sailan Chang, Shanliang Dong, Lihua Qiu*, and Xinfang Xu*, Acid-Promoted Bicyclization of Diaryl Alkynes: Synthesis of 2H-Indazoles with in Situ Generated Diazonium Salt as Nitrogen Source. J. Org. Chem. 2018, 83, 9125-9136.
55. Ju Cai, Bing Wu, Guangwei Rong, Cheng Zhang, Lihua Qiu*, and Xinfang Xu*, Gold-Catalyzed Bicyclization of Diaryl Alkynes: Synthesis of Polycyclic Fused Indole and Spirooxindole Derivatives. Org. Lett. 2018, 20, 2733-2736.
54. Cheng Zhang, Shanliang Dong, Yang Zheng, Ciwang He, Jiaolong Chen, Jingsen Zhen, Lihua Qiu*, and Xinfang Xu*, Synthesis of Spiro-4 H-Pyrazole-Oxindoles and Fused 1 H-Pyrazoles via Divergent, Thermally Induced Tandem Cyclization/migration of Alkyne-Tethered Diazo Compounds. Org. Biomol. Chem. 2018, 16, 688-692.
53. Yang Zheng, Lihua Qiu*, Kemiao Hong, Shanliang Dong, and Xinfang Xu*, Copper- or Thermally Induced Divergent Outcomes: Synthesis of 4-Methyl 2H-Chromenes and Spiro-4H-Pyrazoles. Chem. Eur. J. 2018, 24, 6705-6711.
52. Yang Zheng, Ming Bao, Ruwei Yao, Lihua Qiu*, and Xinfang Xu*, Palladium-Catalyzed Carbene/Alkyne Metathesis with Enynone as Carbene Precursor: Synthesis of Fused Polyheterocycles. Chem. Commun. 2018, 54, 350-353.
51. Ming Bao, Wei Lu, Han Su, Lihua Qiu*, and Xinfang Xu*, A Convergent Formal [4+2] Cycloaddition of 1,6-Diynes and Benzyl Azides: Construction of Spiro-polyheterocycles. Org. Biomol. Chem. 2018, 16, 3258-3265.
50. Xiaolu Zhang, Yang Zheng, Lihua Qiu*, and Xinfang Xu*, Thermally Induced N–S Bond Insertion Reaction of Diazo Compounds with N-Sulfenylsuccinimides: Synthesis of Sulfides and Mechanism Studies. Org. Biomol. Chem. 2018, 16, 70-76.
49. Ming Bao, Wei Lu, Yanping Cai, Lihua Qiu*, and Xinfang Xu*, Gold(I)-Catalyzed Cyclization/Carbonylation Cascade Reaction of 1,6-Diynes: An Access to β,γ-Unsaturated Ketones. J. Org. Chem. 2017, 82, 13386-13395.
48. Yang Zheng, Yongjian Chi, Ming Bao, Lihua Qiu*, and Xinfang Xu*, Gold-Catalyzed Tandem Dual Heterocyclization of Enynones with 1,3,5-Triazines: Bicyclic Furan Synthesis and Mechanistic Insights. J. Org. Chem. 2017, 82, 2129-2135.
47. Yang Zheng, Ming Bao, Lihua Qiu*, and Xinfang Xu*, Thermally Induced Reaction of Diazoamides with Isatins: A Complementary Approach to the 3,3′-Bioxindole Derivatives. Tetrahedron Lett. 2017, 58, 3390-3393.
46. Cheng Zhang, Jingjing Huang, Lihua Qiu*, and Xinfang Xu*, Thermally Induced [3+2] Cycloaddition of Alkynyl-Tethered Diazoamides: Synthetic and Mechanistic Insights. Org. Lett. 2016, 18, 6208-6211.
45. Yongming Deng, Chao Pei, Hadi Arman, Kuiyong Dong, Xinfang Xu*, and Michael P. Doyle*, Syntheses of Tetrahydropyridazine and Tetrahydro-1,2-diazepine Scaffolds through Cycloaddition Reactions of Azoalkenes with Enol Diazoacetates. Org. Lett. 2016, 18, 5884-5887.
44. Yongjian Chi, Lihua Qiu*, and Xinfang Xu*, Highly Enantioselective Synthesis of Spirocyclopropyloxindoles via a Rh(II)-catalyzed Asymmetric Cyclopropanation Reaction. Org. Biomol. Chem. 2016, 14, 10357-10361. (Reviewed by Synfacts: 2017, 13, 0067)
43. Yang Zheng, Xiaolu Zhang, Ruwei Yao, Yuecheng Wen, Jingjing Huang, and Xinfang Xu*, 1,3-Dipolar Cycloaddition of Alkyne-Tethered N-Tosylhydrazones: Synthesis of Fused Polycyclic Pyrazoles. J. Org. Chem. 2016, 81, 11072-11080.
42. Cheng Zhang, Sailan Chang, Lihua Qiu, and Xinfang Xu*, Chemodivergent Synthesis of Multi-substituted/fused Pyrroles via Copper-catalyzed Carbene Cascade Reaction of Propargyl α-Iminodiazoacetates. Chem. Commun. 2016, 52, 12470-12473.
41. Xiangbo Wang, Kuiyong Dong, Bin Yan, Cheng Zhang, Lihua Qiu*, and Xinfang Xu*, NBS-Mediated Dinitrogen Extrusion of Diazoacetamides under Catalyst-free Conditions: Practical Access to 3-Bromooxindole Derivatives. RSC Adv. 2016, 6, 70221-70225.
40. Kuiyong Dong, Bin Yan, Sailan Chang, Yongjian Chi, Lihua Qiu*, and Xinfang Xu*, Transition Metal-Free Fluoroarylation of Diazoacetamides: A Complementary Approach to 3-Fluorooxindoles. J. Org. Chem. 2016, 81, 6887-6892.
39. Yang Zheng, Rongjian Bian, Xiaolu Zhang, Ruwei Yao, Lihua Qiu, Xiaoguang Bao*, and Xinfang Xu*, Catalyst-Free S-S Bond Insertion Reaction of a Donor/Acceptor-Free Carbene by a Radical Process: A Combined Experimental and Computational Study. Eur. J. Org. Chem. 2016, 2016, 3872-3877.
38. Xiangbo Wang, Yunfei Zhou, Lihua Qiu, Ruwei Yao, Yang Zheng, Cheng Zhang, Xiaoguang Bao*, and Xinfang Xu*, Enantioselective Carbene Cascade: An Effective Approach to Cyclopentadienes and Applications in Diels-Alder Reactions. Adv. Synth. Catal. 2016, 358, 1571-1576.
37. Ruwei Yao, Guangwei Rong, Bin Yan, Lihua Qiu*, and Xinfang Xu*, Dual-Functionalization of Alkynes via Copper-Catalyzed Carbene/Alkyne Metathesis: A Direct Access to the 4-Carboxyl Quinolines. ACS Catal. 2016, 6, 1024-1027.
36. Kuiyong Dong, Lihua Qiu*, and Xinfang Xu*, Selective Synthesis of β-Lactams via Catalytic Metal Carbene C-H Insertion Reactions. Curr. Org. Chem. 2016, 20, 29-40.
35. Yang Zheng, Jincheng Mao*, Yuecheng Weng, Xiaolu Zhang, and Xinfang Xu*, Cyclopentadiene Construction via Rh-Catalyzed Carbene/Alkyne Metathesis Terminated with Intramolecular Formal [3+2] Cycloaddition. Org. Lett. 2015, 17, 5638-5641.
34. Yang Zheng, Yue He, Guangwei Rong, Xiaolu Zhang, Yuecheng Weng, Kuiyong Dong, Xinfang Xu*, and Jincheng Mao*, NaI-Mediated Acetamidosulphenylation of Alkenes with Nitriles as the Nucleophiles: A Direct Access to Acetamidosulfides. Org. Lett. 2015, 17, 5444-5447.
33. Guangwei Rong, Jincheng Mao*, Yang Zheng, Ruwei Yao, and Xinfang Xu*, Cu-Catalyzed Direct Cyanation of Terminal Alkynes with AMBN or AIBN as the Cyanation Reagent. Chem. Commun. 2015, 51, 13822-13825.
32. Yang Zheng, Jincheng Mao*, Guangwei Rong, and Xinfang Xu*, A NCS Mediated Oxidative C-H Bond Functionalization: Direct Esterfication between a C(sp3)-H Bond and Carboxylic Acids. Chem. Commun. 2015, 51, 8837-8840.
31. Xinfang Xu*, Yongming Deng, David N. Yim, Peter Y. Zavalij, and Michael P. Doyle*, Enantioselective cis-β-Lactam Synthesis by Intramolecular C-H Functionalization from Enoldiazoacetamides and Derivative Donor-acceptor Cyclopropenes. Chem. Sci. 2015, 6, 2196-2201.
30. Xinfang Xu*, Xiangbo Wang, Peter Y. Zavalij, and Michael P. Doyle*, Straightforward Access to the [3.2.2]Nonatriene Structural Framework via Intramolecular Cyclopropenation/Buchner Reaction/Cope Rearrangement Cascade. Org. Lett. 2015, 17, 790-793.
29. Yang Zheng, Jincheng Mao*, Jie Chen, Guangwei Rong, Defu Liu, Hong Yan, Yongjian Chi, and Xinfang Xu*, Unexpected C=N Bond Formation via NaI-Catalyzed Oxidative de-tetra-Hydrogenative Cross-couplings Between N,N-Dimethyl Aniline and Sulfamides. RSC Adv. 2015, 5, 50113-50117.
28. Xinfang Xu*, and Michael P. Doyle*, Divergent Pathways of β, γ-Unsaturated α-Diazocarbonyl Compounds Catalyzed by Dirhodium and Lewis Acids Catalysts Separately or in Combination. Chin. Chem. Lett. 2015, 26, 227-232.
27. Xinfang Xu*, and Michael P. Doyle*, Recent Developments in the Synthetic Uses of Silyl-protected Enoldiazoacetates for Heterocyclic Syntheses. Aust. J. Chem. 2014, 67, 365-373.
26. Xinfang Xu, and Michael P. Doyle*, The [3+3]-Cycloaddition Alternative for Heterocycle Syntheses: Catalytically Generated Metalloenolcarbenes as Dipolar Adducts. Acc. Chem. Res. 2014, 47, 1396-1405.
25. Xinfang Xu, Xin Guo, Xingchun Han, Liping Yang, and Wenhao Hu*, Highly Diasteroselective Intermolecular 1,3-Dipolar Cycloaddition Reactions of Carbonyl Ylides with Aldimines to Afford Sterically Disfavored cis-Oxazolidines. Org. Chem. Front. 2014, 1, 181-185.
24. Davide Angelonee, Apparao Draksharapu, Wesley.R. Browne*, M.M.R. Choudhuri, Robert Crutchley*, Xichen Xu, Xinfang Xu, and Michael P. Doyle*, Dinuclear Compounds without a Metal-metal Bond. Dirhodium(III,III) Carboxamidates. Inorg. Chim. Acta. 2015, 424, 235-240.
23. Xinfang Xu, Peter Y. Zavalij, and Michael P. Doyle*, Highly Enantioselective Dearomatizing Formal [3+3]-Cycloaddition Reactions of N-Acyliminopyridinium Ylides with Electrophilic Enolcarbene Intermediates. Angew. Chem. Int. Ed. 2013, 52, 12664-12668.
22. Xinfang Xu, Peter Y. Zavalij, and Michael P. Doyle*, A Donor-acceptor Cyclopropene as a Dipole Source for a Silver(I) Catalyzed Asymmetric Catalytic [3+3]-Cycloaddition with Nitrones. Chem. Commun. 2013, 49, 10287-10289.
21. Maxim O. Ratnikov, Xinfang Xu, and Michael P. Doyle*, Simple and Sustainable Iron-Catalyzed Aerobic C-H Functionalization of N,N Dialkylanilines. J. Am. Chem. Soc. 2013, 135, 9475-9479 (co-first author).
20. Xinfang Xu, Xichen Xu, Peter Y. Zavalij, and Michael P. Doyle*, Dirhodium(II)-Catalyzed Formal [3+2+1]-Annulation of Azomethine Imines with Two Molecules of a Diazo Ketone. Chem. Commun. 2013, 49, 2762-2764.
19. Xinfang Xu, Peter Y. Zavalij, Wenhao Hu, and Michael P. Doyle*, Vinylogous Reactivity of Enol Diazoacetates with Donor–Acceptor Substituted Hydrazones. Synthesis of Substituted Pyrazole Derivatives. J. Org. Chem. 2013, 78, 1583-1588.
18. Xinfang Xu, Peter Y. Zavalij, and Michael P. Doyle*, Synthesis of Tetrahydropyridazines by a Metal-Carbene-Directed Enantioselective Vinylogous N-H Insertion/Lewis Acid-Catalyzed Diastereoselective Mannich Addition. Angew. Chem. Int. Ed. 2012, 51, 9829-9833. (Reviewed by Synfacts: 2012, 8, 1181)
17. Yu Qian, Xinfang Xu, Xiaochen Wang, Peter Y. Zavalij, Wenhao Hu, and Michael P. Doyle*, Rhodium(II)- and Copper(II)-Catalyzed Reactions of Enol Diazoacetates with Nitrones: Metal Carbene versus Lewis Acid Directed Pathways. Angew. Chem. Int. Ed. 2012, 51, 5900-5903. (Reviewed by Synfacts: 2012, 8, 0861)
16. Xinfang Xu, Peter Y. Zavalij, Wenhao Hu, and Michael P. Doyle*, Efficient Synthesis of Oxazoles by Dirhodium(II)-catalyzed Reactions of Styryl diazoacetate with Oximes. Chem. Commun. 2012, 48, 11522-11524.
15. Xinfang Xu, Dmitry Shabashov, Peter Y. Zavalij, and Michael P. Doyle*, Unexpected Catalytic Reactions of Silyl-Protected Enol Diazoacetates with Nitrile Oxides That Form 5-Arylaminofuran-2(3H)-one-4-carboxylates. Org. Lett. 2012, 14, 800-803.
14. Xinfang Xu, Dmitry Shabashov, Peter Y. Zavalij, and Michael P. Doyle*, Substrate-Dependent Divergent Outcomes from Catalytic Reactions of Silyl-Protected Enol Diazoacetates with Nitrile Oxides: Azabicyclo[3.1.0]hexanes or 5-Arylaminofuran-2(3H)-ones. J. Org. Chem. 2012, 77, 5313-5317.
13. Xinfang Xu, Wenhao Hu, Peter Y. Zavalij, and Michael P. Doyle*, Divergent Outcomes of Carbene Transfer Reactions from Dirhodiumand Copper-Based Catalysts Separately or in Combination. Angew. Chem. Int. Ed. 2011, 50, 11152-11155.
12. Xinfang Xu, Wenhao Hu, and Michael P. Doyle*, Highly Enantioselective Catalytic Synthesis of Functionalized Chiral Diazoacetoacetates. Angew. Chem. Int. Ed. 2011, 50, 6392-6395. (Reviewed by Synfacts: 2011, 9, 0976)
11. Xiaochen Wang, Xinfang Xu, Peter Y. Zavalij, and Michael P. Doyle*, Asymmetric Formal [3+3]-Cycloaddition Reactions of Nitrones with Electrophilic Vinylcarbene Intermediates. J. Am. Chem. Soc. 2011, 133, 16402-16405 (co-first author).
10. Xinfang Xu, Maxim O. Ratnikov, Peter Y. Zavalij, and Michael P. Doyle*, Multifunctionalized 3-Hydroxypyrroles in a Three-Step, One-Pot Cascade Process from Methyl 3-TBSO-2-diazo-3-butenoate and Nitrones. Org. Lett. 2011, 13, 6122-6125.
9. Phong Truong, Xinfang Xu, and Michael P. Doyle*, An Efficient Methodology to Substituted Furans via Oxidation of Functionalized α-Diazo-β-ketoacetates. Tetrahedron Lett. 2011, 52, 2093-2096.
8. Xinfang Xu, Yu Qian, Liping Yang, and Wenhao Hu*, Cooperative Catalysis in Highly Enantioselective Mannich-type Three-Component Reaction of a Diazoacetophenone with an Alcohol and an Imine. Chem. Commun. 2011, 47, 797-799. (Reviewed by Synfacts: 2011, 3, 0304)
7. Jing Zhou, Xinfang Xu, and Wenhao Hu*, Enantioselective Three-Component Reaction for the Preparation of β-Amino-α-hydroxyesters. Org. Synth. 2011, 88, 418-426.
6. Wenhao Hu*, Jing Zhou, Xinfang Xu, Weijun Liu, and Liuzhu Gong, (R)-3,3'-Bis(9-phenanthryl)-1,1'-Binaphthalene-2,2'-Diyl Hydrogen Phosphate. Org. Synth. 2011, 88, 406-417.
5. Yu Qian, Xinfang Xu, Liqin Jiang, Dipak Prajapati, and Wenhao Hu*, A Strategy to Synthesize Taxol Side Chain and (-)-epi Cytoxazone via Chiral Brønsted Acid-Rh2(OAc)4 Co-catalyzed Enantioselective Three-Component Reactions. J. Org. Chem. 2010, 75, 7483-7486.
4. Xinfang Xu, Xinchun Han, Liping Yang, and Wenhao Hu*, Highly Diastereoselective Synthesis of Fully Substituted Tetrahydrofurans by a One-Pot Cascade Reaction of Aryldiazoacetates with Allyl Alcohols. Chem. Eur. J. 2009, 15, 12604-12607. (Reviewed by Synfacts: 2010, 2, 0186)
3. Dong Xing, Xinfang Xu, and Liping Yang*, Highly Chemoselective Rearrangement of 3-Aryloxaziridines to Nitrones or Amides. Synthesis, 2009, 3399-3404.
2. Wenhao Hu*, Xinfang Xu, Jing Zhou, Weijun Liu, Haoxi Huang, Juan Hu, Liping Yang, and Liuzhu Gong*, Cooperative Catalysis with Chiral Brønsted Acid-Rh2(OAc)4: Highly Enantioselective Three-Component Reactions of Diazo Compounds with Alcohols and Imines. J. Am. Chem. Soc. 2008, 130, 7782-7783.
1. Xinfang Xu, Jing Zhou, Liping Yang, and Wenhao Hu*, Selectivity Control in Enantioselective Four-component Reactions of Aryl Diazoacetates with Alcohols, Aldehydes and Amines: an Efficient Approach to Synthesizing Chiral β-Amino-α-hydroxyesters. Chem. Commun. 2008, 44, 6564-6566. (Reviewed by Synfacts: 2009, 2, 0173)
