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成果及论文

41. Divergent Synthesis of 17‐nor‐Cephalotane Diterpenoids through Developed Ynol‐diene Cyclization - Sun - 2024 - Angewandte Chemie International Edition - Wiley Online Library

    Zezhong Sun, Xin Shu, Fuli Ma, Ao Li, Yali Li, Shuang Jin, Yunxia Wang, Xiangdong Hu*.Angew. Chem. Int. Ed. 2024, e202407757.

Description unavailable


40. DNDMH-mediated direct nitration of aryl alkenes - Chemical Communications (RSC Publishing)

     Lihua Niu,Hao Guo,Fuqiang Jia, Jiayu Shen, Yunxia Wang, Xiangdong Hu*.Chem. Commun.2024, 60, 3202.

Graphical abstract: DNDMH-mediated direct nitration of aryl alkenes


39. Enantioselective Total Synthesis of (−)‐Cephalotanin B - Sun - Angewandte Chemie International Edition - Wiley Online Library.

     Zezhong Sun, Shuang Jin, Jianing Song, Lihua Niu, Fan Zhang, Han Gong, Xin Shu, Yunxia Wang, Xiangdong HuAngew. Chem. Int. Ed202362

Details are in the caption following the image


38Dinitro-5,5-Dimethylhydantoin: An Arene Nitration Reagent | Organic Letters (acs.org).

     Fuqiang Jia, Ao Li, Xiangdong Hu*.Org. Lett202325, 4605-4609.


37. Thieme E-Journals - Synlett / Abstract (thieme-connect.de).

      Fan Zhang, Chongchong Chen, Xiangdong Hu*.Synlett. 202334.


36.Total Synthesis of (−)-Ceforalide B and (−)-Cephanolides B–D | Organic Letters (acs.org).

     Zhongliu Sun, Xin Fan, Zezhong Sun, Zhijie Li, Lihua Niu, Hao Guo, Zhiqiang Ren, Yunxia Wang, Xiangdong Hu*. Org. Lett2022, 24, 7507-7511.


35. Construction of Tetracyclic Core Skeleton of Cephalotaxus Diterpenoids through Diastereoselective Pauson‐Khand Reaction - Chen - 2022 - European Journal of Organic Chemistry - Wiley Online Library.

     Chong-Chong Chen, Zhiqiang Ren, Zhongliu Sun, Zezhong Sun, Xin Shu, Yunxia Wang, Xiangdong Hu*. Eur. J. Org. Chem20212022.

Description unavailable


34. Synthesis and Bioactivity of Tropone Derivatives as Potential Compounds against Human Gastric Cancer Cells Growth (sioc-journal.cn).

     邵继炎, 李志杰, 王迓君,  熊裕焱*, 胡向东*,Chin. J. Org. Chem2021, 41, 3675-3681.


33. Enantioselective Total Synthesis of (−)‐Spiroxins A, C, and D - Shu - 2021 - Angewandte Chemie International Edition - Wiley Online Library.

    Xin Shu, Chong-Chong Chen , Tao Yu, Jiayi Yang, Xiangdong Hu*. Angew. Chem. Int. Ed202160, 18514-18518.

Details are in the caption following the image


32. Total Synthesis of (+)‐3‐Deoxyfortalpinoid F, (+)‐Fortalpinoid A, and (+)‐Cephinoid H - Ren - 2021 - Angewandte Chemie International Edition - Wiley Online Library.

     Zhiqiang Ren , Zhongliu Sun , Yifei Li, Xin Fan, Mingda Dai, Yunxia Wang, Xiangdong Hu*. Angew. Chem. Int. Ed2021, 60, 18572-18576.

Description unavailable


31. 抗结核分枝杆菌生物碱Pseudopteroxazole和Ileabethoxazole的全合成研究进展 (sioc-journal.cn).

     孙泽众, 徐苗, 王云侠*, 胡向东*. Chin. J. Org. Chem2020, 40, 4203-4215.


30. Enantioselective Total Synthesis of Pseudopteroxazole and Ileabethoxazole - Zhang - 2019 - Angewandte Chemie International Edition - Wiley Online Library.

     Xuan Zhang, Xianhe Fang, Miao Xu, Yibo Lei, Zibo Wu, Xiangdong Hu*. Angew. Chem. Int. Ed201958, 7845-7849.

Description unavailable


29. Molecules | Free Full-Text | Advances in the Synthesis of Lignan Natural Products (mdpi.com).

    Xianhe Fang, Xiangdong Hu*. Molecules, 201823, 3385.


28. Thieme E-Journals - Synlett / Abstract (thieme-connect.de).

       Tao Yu
Xin Shu, 
Kewu Yang
Xiangdong Hu*. Synlett,  2018 29 , 1617-1621.

27. Asymmetric total synthesis of (+)-ovafolinins A and B - Chemical Communications (RSC Publishing).

     Xianhe Fang, Lei Shen, Xiangdong Hu*.Chem. Commun. 201854, 7539-7541.


26A concise synthetic approach to parvistemin A and (±)-diperezone - Organic Chemistry Frontiers (RSC Publishing).

     Songsong Gao, Xiangdong Hu*. Org. Chem. Front. 20174, 1493-1498.

25. Nickel-catalyzed ring-opening of α-hydroxycyclobutenones with a remarkable ligand effect - Chemical Communications (RSC Publishing).

     Songsong Gao, Xiangdong Hu*.Chem. Commun201753, 10540-10543.


24. Racemic synthesis of an intermediate for the formal synthesis of madindoline A and B: Synthetic Communications: Vol 46, No 12 (tandfonline.com).

     Qing Li, Fenfen Xiao, Yunxia Wang, Xiangdong Hu*. Synth. Commun.201646, 1062-1067.


23. Total Synthesis and Structural Reassignment of (±)-Cereoanhydride | Organic Letters (acs.org).

     Zhiqiang Ren, Yu Hao, Xiangdong Hu*. Org. Lett201618, 4958-4961.

Figure 1

22. Stereocontrolled [4+1] Annulation of α‐Hydroxycyclobutenones: Synthesis of Polysubstituted Cyclopentenones - Mao - 2016 - Advanced Synthesis & Catalysis - Wiley Online Library.

     Xu Mao, Peidong Song, Yu Hao, Zezhong Sun, Xiangdong Hu*, Adv. Synth. Catal2016358, 3719-3723.

 image


21. Four‐Electron Electrocyclic Ring‐Opening/Intermolecular [4+2] Cycloadditions of α‐Hydroxycyclobutenones: Stereoselective Synthesis of Multiple Substituted δ‐Lactams - Song - 2016 - Advanced Synthesis & Catalysis - Wiley Online Library.

     Peidong Song, Qing Li, Congcong Wang, Wenfa Wu, Xu Mao, Jiajia Wang, Xiangdong HuAdv. Synth. Catal2016358, 1208-1212.

image


20. Intermolecular atom transfer radical addition of α,α,α-trichloromethyl ketones and alkenes mediated by a CuCl/bpy system - ScienceDirect.

     Abulikemu Abudu Rexit, Xiangdong Hu*Tetrahedron, 2015, 71, 2313-2316.


19. Thieme E-Journals - Synthesis / Abstract (thieme-connect.de).

     Fenfen Xiao, Qing Zhang,Yunxia Wang*, Xiangdong Hu*Synthesis, 2015, 47, 2545-2548.


18. Reactions of Tertiary Allylic Amines and Dichlorocarbenes: Synthetic Communications: Vol 45, No 19 (tandfonline.com).

     Meili Wang, Fenfen Xiao, Yinjuan Bai, Xiangdong Hu*. Synth. Commun.201545, 2259-2265.


17. Total Synthesis of Asterredione | The Journal of Organic Chemistry (acs.org).

16. Protecting-Group-Free Synthesis of Taiwaniaquinone H Using a One-Pot Thermal Ring Expansion/4π-Electrocyclization Strategy | The Journal of Organic Chemistry (acs.org).

    Xiuxiang Yan, Xiangdong Hu*. J. Org. Chem201479, 5282-5286.

Figure 1


15. Total Synthesis of Carbazomycin G by a Thermal Ring Expansion/Self‐Redox Reaction Cascade - An - 2014 - European Journal of Organic Chemistry - Wiley Online Library.

    Yong An, Yunxia Wang, Xiangdong Hu*. Eur. J. Org. Chem2014, 3715-3718.

14. Total Synthesis of Mansonone E - Xianhe Fang, Xiangdong Hu, 2014 (sagepub.com).

   Xianhe Fang, Xiangdong Hu*. J. Chem Res. 201438, 137-139.


13. Concise Synthesis of Linderaspirone A and Bi‐linderone - Xiao - 2013 - Asian Journal of Organic Chemistry - Wiley Online Library.

   Fenfen Xiao,  Wu Liu, Yunxia Wang, Qing Zhang, Xiang Li,  Xiangdong Hu*. Asian J. Org. Chem2013, 2, 216 -219.

12. Concise Synthesis of Lucidone and Methyl Lucidone (sioc-journal.cn).

   Wu Liu, Fenfen Xiao, Xiangdong HuChin. J. OrgChem2013, 33, 1587-1590.


11. Thieme E-Journals - Synlett / Abstract (thieme-connect.de).

 
          Wenmin Dong
, 
Moran Zhang
,
 
Fenfen Xiao
, 
Yunxia Wang,
 
Wu Liu,
 
Xiangdong Hu*,
 
Qiang Yuan,
 
Shaofei Zhang.  Synlett.  2012,  23, 2799-2802.

10. An Alternative Approach to Direct Aldol Reaction Based on Gold‐Catalyzed Methoxyl Transfer - Zhang - 2012 - Advanced Synthesis & Catalysis - Wiley Online Library

  Moran Zhang, Yunxia Wang, Yang Yang, Xiangdong HuAdv. Synth. Catal2012354, 981-985.

Description unavailable


9. Kinetic target-guided synthesis - Chemical Society Reviews (RSC Publishing)

  Xiangdong Hu, Roman Manetsch*. Chem. Soc. Rev.201039, 1316-1324.


8. Bcl-XL-Templated Assembly of Its Own Protein−Protein Interaction Modulator from Fragments Decorated with Thio Acids and Sulfonyl Azides | Journal of the American Chemical Society (acs.org)

  Xiangdong Hu, Jiazhi Sun, Hong-Gang Wang, Roman Manetsch* J. Am. Chem. Soc., 2008130, 13820-13821.


7. A simple base-mediated amidation of aldehydes with azides - Chemical Communications (RSC Publishing)

   Sameer S. Kulkarni, Xiangdong Hu, Roman Manetsch*.Chem. Commun., 2013, 49, 1193-1195.

Graphical abstract: A simple base-mediated amidation of aldehydes with azides

6. Screening of Protein–Protein Interaction Modulators via Sulfo-Click Kinetic Target-Guided Synthesis | ACS Chemical Biology

    Sameer S. Kulkarni, Xiangdong Hu, Kenichiro Doi, Hong-Gang Wang, Roman Manetsch*.ACS Chem. Biol. 2011, 6, 724–732.

Before 2006:

5. KOtBu-Promoted Three-Component Coupling of Aldehydes and Alkynes:  Highly Efficient Synthesis of 1-En-4-yn-3-ols and 2-En-4-yn-1-ols | The Journal of Organic Chemistry

    Shao-Hua Wang, Yong-Qiang Tu,* Peng Chen, Xiang-Dong Hu, Fu-Min Zhang, and Ai-Xia Wang. J. Org. Chem. 2006, 71, 4343-4345.

4. Synthetically Useful Wagner–Meerwein Rearrangement of α‐Quaternary β‐Bromovinyl Methyl Ethers - Wang - 2006 - European Journal of Organic Chemistry - Wiley Online Library

   Ai-Xia WangYong-Qiang Tu,* Zhen-Lei Song, Dao-Yi Yuan, Xiang-Dong HuShao-Hua Wang,  Shuan-Hu Gao.Eur.J.Org.Chem.2006,2691–2694.

3. Total Synthesis of (±)-Galanthamine | Organic Letters (acs.org)

    Xiang-Dong Hu, Yong Qiang Tu,* En Zhang, Shuanhu Gao, Shaohua Wang, Aixia Wang, Chun-An Fan,Min Wang Org. Lett. 20068, 1823-1825.  

2.  A Tandem Semipinacol Rearrangement/Alkylation of α‐Epoxy Alcohols: An Efficient and Stereoselective Approach to Multifunctional 1,3‐Diols - Hu - 2004 - Angewandte Chemie International Edition - Wiley Online Library

    Xiang-Dong Hu, Chun-An Fan, Fu-Min Zhang, Yong Qiang Tu* Angew. Chem. Int. Ed. 200443, 1702-1705.   

1. Progressive Studies on the Novel Samarium‐Catalyzed Diastereoselective Tandem Semipinacol Rearrangement/Tishchenko Reduction of Secondary α‐Hydroxy Epoxides - Fan - 2003 - Chemistry – A European Journal - Wiley Online Library

    Chun-An Fan, Xiang-Dong Hu, Yong-Qiang Tu,* Bao-Min Wang, and Zhen-Lei Song.Chem. Eur. J. 2003, 9, 430-4310.