2024年
Yongli Zhao, Dingsheng Cao, Jie-Ping Wan,* Yunyun Liu.* Site Specific C3-Alkenylation of Indoles Mediated by in situ C-H Iodination. Asian Journal of Organic Chemistry 2024, in press, DOI: 10.1002/ajoc.202400599. Link
Leiqing Fu,* Hongxiang Huang, Yingying Jiang, Xuan Liu, Huimin Chen, Jie-Ping Wan.* Copper(II)-Catalyzed [2+2+2] Annulation of Enaminones with Maleimides Using a Traceless Directing Group Strategy. Advanced Synthesis & Catalysis 2024, 366(19), 4139-4144. Link
Wenli Tong, Jie-Ping Wan,* Jianchao Liu.* Synthesis of C-glycosides enabled by palladium-catalyzed glycosylation reactions. Organic Chemistry Frontiers 2024, 11(23), 6918-6941. Link
Xiuli Li, Yunyun Liu,* Jie-Ping Wan.* Cascade [3 + 2] Annulation of 1,3-Dicarbonyl Compounds and Ethyl Secondary Amines for Pyrrole Synthesis via Poly C(sp3)-H Bond Functionalization. Journal of Oganic Chemistry 2024, 89(21), 16049-16054. Link
Lihong Tian, Jie-Ping Wan,* Yunyun Liu.* Transition metal-free thiophene construction in pure water by multiplied C-H functionalization with enaminones and elemental sulfur. Green Synthesis and Catalysis 2024, DOI: 10.1016/j.gresc.2024.09.002. Link
Zhi Tu, Jie-Ping Wan, Li Wei,* Yunyun Liu.* Iridium-catalyzed reduction of o-hydroxyl phenyl enaminones for the synthesis propiophenones and their application in 3-methyl chromone synthesis. Oganic & Biomolecular Chemistry 2024, 22(41), 8279-8284. Link
Jing Zhou, Quanquan Zhou,* Jie-Ping Wan.* Recent Advances in Multicomponent Synthesis of Pyrazoles. Organic & Biomolecular Chemistry, 2024, 22(40), 8065-8077. (Invited contribution) Link
Zhouying Wang, Lu Gan, Zhibin Song, Yunyun Liu, Jie-Ping Wan.* tBuOK/TMSOK-Mediated “Alkyl Halide to Alkyl Free Radical” Transformation for Transition-Metal-Free Benzoin α-C—H Alkylation. Chinese Journal of Chemistry, 2024, 42(23), 3041-3046. Link
Junlong Zeng, Tao Zhou, Jianchao Liu,* Jie-Ping Wan.* Photocatalytic Pyridine Synthesis with Enaminones and TMEDA under Metal-Free Conditions. Journal of Organic Chemistry 2024, 89(15), 11060-11066. Link
Dingsheng Cao, Jie-Ping Wan, Yunyun Liu.* Synthesis of Chromone-3-phosphonates via Arbuzov-Type C-P Cross Coupling from o-Hydroxyphenyl Enaminones and Phosphites. Advanced Synthesis & Catalysis 2024, 366(17), 3670-3675. Link
Xinyuan Wen, Jie-Ping Wan, Ming Zhang,* Yunyun Liu.* Rh-catalyzed three-component synthesis of diverse N-aryl pyrazoles via cascade pyrazole annulation and aryl C-H addition to alkenes. Applied Organometallic Chemistry, 2024, 38(9), e7626. Link
Enrong Tang, Qaun-Quan Zhou,* Jie-Ping Wan.* Visible-light-induced Ritter-type amidation of α-hydroxy ketones in the selectively synthesis of α,α-diamido and monoamido ketones. Chemical Communications 2024, 60(58), 7471-7474. Link
Qihui Huang, Jianchao Liu,* Jie-Ping Wan.* Electrochemical Enaminone-Thioamide Annulation and Thioamide Dimeric Annulation for the Tunable Synthesis of Thiazoles and 1,2,4-Thiadiazole. Organic Letters 2024, 26(25), 5263-5268. Link
Jinbiao Ying, Tao Zhou, Yunyun Liu, Liyun Zhou,* Jie-Ping Wan.* Transition-Metal-Free C–H Trifluoromethylthiolation of N,N-Disubstituted Enaminones To Access CF3S-Functionalized Enaminones and Their Application in the Synthesis of CF3S-Heteroaryls. Journal of Organic Chemistry 2024, 89(12), 9078-9085. Link
Qihui Huang, Changfeng Wan,* Jie-Ping Wan.* Photocatalytic Annulation of Enaminones with Thioureas for the Synthesis of 2-Aminothiazoles via Tandem C-S and C-N Bond Formation. Synthesis 2024, 56(16), 2565-2571. Link (Invited contribution)
Kang Chen, Jie-Ping Wan, Liyun Zhou,* Yunyun Liu.* PIFA-mediated room temperature dehydrogenative annulation for the synthesis of 2-alkenyl oxazoles. Journal of Molecular Structure 2024, 1308, 138142. Link.
Tao Zhou, Jing Zhou, Yunyun Liu, Jie-Ping Wan,* Fen-Er Chen.* Transition metal-free tunable synthesis of 3-(trifluoromethylthio) and 3-trifluoromethylsulfinyl chromones via domino C-H functionalization and chromone annulation of enaminones. Chinese Chemical Letters 2024, 35(11), 109683. Link
Yunyun Liu,* Leiling Deng, Haijin Guo, Jie-Ping Wan.* Annulative Nonaromatic Newman-Kwart Type Rearrangement for the Synthesis of Sulfur Heteroaryls. Organic Letters 2024, 26(1), 46-50. Link
Zhouying Wang, Enrong Tang, Quanquan Zhou,* Jie-Ping Wan.* Metal-free photocatalytic homo- and cross dimerization of a-hydroxy ketones via dual C(sp3)-H functionalization: synthesis of 2,3-dihydroxy-1,4-butanediones. Organic Chemistry Frontiers, 2024, 11(4), 1157-1162. Link
Haijin Guo, Yunyun Liu,* Jie-Ping Wan.* Electrochemical cascade pyrazole annulation and C-H halogenation for the synthesis of 4-halopyrazoles. Green Synthesis and Catalysis 2024, in press, DOI: 10.1016/j.gresc.2023.10.004.Link
Haozhi Wu, Kang Chen, Yunyun Liu, Jie-Ping Wan.* Unlock the C-N Bond Amidation of Enaminones: Metal-Free Synthesis of Enamides by Water Assisted Transamidation. Journal of Organic Chemistry 2024, 89(1), 216-223. Link
Jianchao Liu,* Jie-Ping Wan, Yunyun Liu.* Electrochemical difunctionalization of alkenes and alkynes for the synthesis of organochalcogens involving C–S/Se bond formation. Organic Chemistry Frontiers 2024, 11(2), 597-630. Link
Cai Zhang,* Jie-Ping Wan.* Synthesis of Hypervalent Iodine Diazo Compounds and Their Application in Organic Synthesis. Chemistry-A European Journal, 2024, 30(5), e202302718. Link
Yu Han, Liyun Zhou, Chengyu Wang,* Shangti Feng,* Rong Ma, Jie-Ping Wan.* Recent advances in visible light-mediated chemical transformations of enaminones. Chinese Chemical Letters, 2024, 35(2),108977. Link
2023年
Jingfeng Ye, Yunyun Liu, Jin Luo,* Jie-Ping Wan.* “Alkene-to-Alkene” Difunctionalization of Enaminones for the Synthesis of Polyfunctionalized Alkenes by Transition-Metal-Free C–H and C–N Bond Transformation. Organic Letters 2023, 25(47), 8451-8456. Link
Xiao Xiao, Puren Han, Jie-Ping Wan, Jinchao Liu.* Stereoselective Synthesis of Indolyl-C-glycosides Enabled by Sequential Aminopalladation and Heck Glycosylation of 2-Alkynylanilines with Glycals. Organic Letters 2023, 25(39), 7170-7175. Link
Leiqing Fu,* Jie-Ping Wan.* Recent advances in transition metal-catalyzed transformations in N,N-disubstituted enaminones. Tetrahedron Letters, 2023, 130, 154766. Link
Lu Gan, Yunyun Liu, Chaoli Wang,* Jie-Ping Wan.* Synthesis of α-Hydroxyl Ketones by Metal-Free C=C Double Bond Cleavage of Enaminones in Aqueous Medium. ChemistrySelect 2023, 8(31), e202301791. Link
Demao Chen, Liyun Zhou, Chengping Wen,* Jie-Ping Wan.* Three-Component Chemo-Selective Synthesis of N-(o-Alkenylaryl) Pyrazoles by Pyrazole Annulation and Rh-Catalyzed Chemo-Selective Aryl C–H Addition Cascade. Journal of Organic Chemistry 2023, 88(13), 8619-8627. Link
Huan Gao, Liyun Zhou, Jie-Ping Wan, Yunyun Liu.* Rongalite as C1 Synthon in the Synthesis of Divergent Pyridines and Quinolines. Journal of Organic Chemistry, 2023, 88(11), 7188-7198. Link
Zukang Zhong,# Lihua Liao,# Yunyun Liu, Ming Zhang, Jie-Ping Wan.* Annulation of Enaminones with Quinonediimides/Quinoneimides for Selective Synthesis of Indoles and 2-Aminobenzofurans. Chemical Communications 2023, 59(45), 6885-6888. Link (# Equal contribution).
Dingsheng Cao, Chaoli Wang, Jie-Ping Wan, Chengping Wen,* Yunyun Liu.* Tunable vicinal, geminal diphosphorylation and C-N bond phosphorylation of enaminones toward divergent phosphorylated ketone derivatives. Chemical Communications 2023, 59(42), 6383-6386. Link
Wenli Song, Yunyun Liu, Nan Yan, Jie-Ping Wan.* Tunable Key [3 + 2] and [2 + 1] Cycloaddition of Enaminones and α-Diazo Compounds for the Synthesis of Isomeric Isoxazoles: Metal-Controlled Selectivity. Organic Letters, 2023, 25(12), 2139-2144. Link
Demao Chen, Changfeng Wan, Yunyun Liu,* Jie-Ping Wan.* Three-Component Fusion to Pyrazolo[5,1-a]isoquinolines via Rh-Catalyzed Multiple Order Transformation of Enaminones. Journal of Organic Chemistry 2023, 88(7), 4833-4838. Link
Demao Chen, Liyun Zhou, Yunyun Liu,* Jie-Ping Wan.* Three-component synthesis of N-naphthyl pyrazoles via Rh(III)-catalyzed cascade pyrazole annulation and Satoh-Miura benzannulation. Chemical Communications. 2023, 59(27), 4036-4039. Link
Baoli Zhao, Xiaoting Yin, Haifeng Li, Kai Cheng,* Jie-Ping Wan.* Transition metal-free, photocatalytic arylation and dioxygenation for vicinal diketone synthesis using alkynes and arene diazonium salts. Organic Chemistry Frontiers 2023, 10(8), 1942-1947. Link
Yan Lin, Jie-Ping Wan, Yunyun Liu.* Cascade in situ Iodination, Chromone Annulation and Cyanation for Site-Selective Synthesis of 2-Cyanochromones. Journal of Organic Chemistry 2023, 88(6), 4017-4023. Link
Cai Zhang,* Demao Chen, Jie-Ping Wan, Yunyun Liu.* Recent Advances in Electrochemical Cascade Cyclization Reactions. Synthesis 2023, 55(18), 2911-2925. Link
Shnaghui Tian, Yunyun Liu, Changfeng Wan, Jie-Ping Wan,* Guifeng Hao.* Catalyst-Free Cascade Annulation of Enaminones and Aryl Diazonium Tetrafluoroboronates for Cinnoline Synthesis and the Anti-Inflammatory Activity Study. Journal of Organic Chemistry 2023, 88(4), 2433-2442. Link
Zhongrong Xu, Jie-Ping Wan,* Yunyun Liu.* Transition Metal-Free C-H Thiocyanation and Selenocyanation by Thermochemical, Photocatalytic and Electrochemical Process. Chinese Journal of Organic Chemistry 2023, 43(7), 2425-2446. Link
Lizhu Huang, Yunyun Liu,* Jie-Ping Wan.* Engineering Biomass Feedstock Cyrene to Value-Added Compounds by Enaminone Platform Construction. Chinese Journal of Organic Chemistry 2023, 43(6), 2096-2103. Link
Zhou Zhang, Jun-Jie Yi, Muhammad Aslam, Jie-Ping Wan,* Meng Sun.* Rh(III)-Catalyzed Stereoselective C-H Homoallylation of Indolines with 4-Vinyl-1,3-dioxan-2-ones. Synthesis 2023, 55(21), 3617-3624. Link
Li-Xia Qaun, Yi Xiao, Anxi Zhou, Xianhong Zhu, Liu-Liang Mao,* Jie-Ping Wan.* Visible-Light-Promoted Tandem Oxyphosphorylation Etherification of α-Diazoesters to Access Phosphoric Esters. ChemistrySelect 2023, 8(2) e202204778. Link
Liu-Liang Mao, Li-Xia Quan, Yunyun Liu, Jie-Ping Wan.* Nitrogen heterocycle construction in aqueous mediums: a sustainable tool for molecular diversity. Current Opinion in Green and Sustainable Chemistry 2023, 40, 100756. Link
Baoli Zhao, Haifeng Li, Fengxuan Jiang, Jie-Ping Wan, Kai Cheng,* Yunyun Liu.* Synergistic Visible Light and Pd-Catalyzed C–H Alkylation of 1-Naphthylamines with α-Diazoesters Journal of Organic Chemistry 2023, 88(1), 640-646. Link
2022年
Kang Chen, Baoli Zhao, Yunyun Liu,* Jie-Ping Wan.* Thiazole-5-carbaldehyde Synthesis by Cascade Annulation of Enam-inones and KSCN with Dess-Martin Periodinane Reagent. Journal of Organic Chemistry 2022, 87(21), 14957-14964.
https://pubs.acs.org/doi/10.1021/acs.joc.2c01881
Junlong Zeng, Jie-Ping Wan, Yunyun Liu.* Photocatalytic C-H Thiocyanation of NH2-Enaminones and the Tunable Synthetic Routes to 2-Aminothiazoles and 2-Thiazolinones. Journal of Organic Chemistry 2022, 87(19), 13195-13203.
https://pubs.acs.org/doi/10.1021/acs.joc.2c01667
Book chapter: Yunyun Liu, Jie-Ping Wan. Chapter 35: Organic Transformations with DCM, CCl4, CHCl3, and CHBr3 and Other Related Reactions. in The Chemical Transformation of C1 Compounds, volume 2. Eds. Kuiling Ding, Xiaofeng Wu, Buxing Han, Zhongmin Liu. Wiley, 2022, DOI: 10.1002/9783527831883.ch35
https://onlinelibrary.wiley.com/doi/10.1002/9783527831883.ch35
Haozhi Wu, Tian Luo, Jianwen Jiang,* Jie-Ping Wan.* KI-Catalyzed Selective C5 Sulfenylation and C5, C7-Disulfenylation of Unprotected 8-Aminoquinolines and the Indole C2, C3-Disulfenylation. Chinese Journal of Organic Chemistry 2022, 42(11), 3721-3729. (Invited contribution)
http://sioc-journal.cn/Jwk_yjhx/CN/10.6023/cjoc202206029
Demao Chen, Jianwen Jiang,* Jie-Ping Wan.* Advances in the Transition Metal-Free C-H Trifluoromethylation. Chinese Journal of Chemistry 2022, 40(21), 2582-2594.
https://onlinelibrary.wiley.com/doi/abs/10.1002/cjoc.202200347
Haozhi Wu, Tian Luo, Jie-Ping Wan, Jianwen Jiang,* Yunyun Liu.* Nickel-Catalyzed Tandem Ring Contraction of TEMPO and C-N Bond Transamination of Enaminones toward Amino Diversity of Enaminones. European Journal of Organic Chemistry 2022, (26), e202200552.
https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.202200552
Haijin Guo, Yunyun Liu, Chengping Wen,* Jie-Ping Wan.* Electrochemical enaminone C-H thiolation/C-N amination cascade for thiazole synthesis and their diastereoselective dearomatization. Green Chemistry 2022, 24(13), 5058-5063.
https://pubs.rsc.org/en/content/articlelanding/2022/gc/d2gc01644c
Yunyun Liu,* Tao Zhang, Jie-Ping Wan.* Ultrasound Promoted Synthesis of α-Thiocyanoketones via Enaminone C=C Double Bond Cleavage and the Tunable One-Pot Access to 4-Aryl-2-aminothiazoles. Journal of Organic Chemistry 2022, 87(12), 8248-8255.
https://pubs.acs.org/doi/10.1021/acs.joc.2c00708
Lizhu Huang, Lu Yang, Jie-Ping Wan, Liyun Zhou,* Yunyun Liu,* Guifeng Hao.* Metal-free three-component assemblies of anilines, α-keto carboxylic acids and alkyl lactates for quinoline synthesis and their anti-inflammatory activity. Organic & Biomolecular Chemistry 2022, 20(21), 4385-4390.
https://pubs.rsc.org/en/content/articlelanding/2022/ob/d2ob00661h
Leiqing Fu,# Wenqiang Xu,# Maoping Pu, Yundong Wu, Yunyun Liu, Jie-Ping Wan.* Rh-Catalyzed [4 + 2] Annulation with a Removable Monodentate Structure toward Iminopyranes and Pyranones by C–H Annulation. Organic Letters, 2022, 24(16), 3003-3008. (# = equal contricution)
https://pubs.acs.org/doi/10.1021/acs.orglett.2c00912
Weiqiao Lan, Fangyi Li, Jintao H u, Jiatong Zhu, Shan Hu, Jie-Ping Wan, Lihua Liao.* Copper-Catalyzed Regiospecific Amination of Heteroarenes with Quinoneimides. Journal of Organic Chemistry 2022, 87(9), 5592-5602.
https://pubs.acs.org/doi/10.1021/acs.joc.1c02873
Zhouying Wang, Baoli Zhao, Yunyun Liu,* Jie-Ping Wan.* Recent Advances in Reactions using Enaminone in Water or Aqueous Medium. Advanced Synthesis & Catalysis 2022, 364(9), 1508-1521.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adsc.202200144
Xin-Wei Guo, Li-Xia Quan,* Xian-Hong Zhu, Fa-Yun Chen, An-Xi Zhou, Liu-Liang Mao,* Jie-Ping Wan, Shang-Dong Yang. Transition-metal-free three-component coupling approach to QUINAP derivatives. Organic & Biomolecular Chemistry 2022, DOI: 10.1039/D1OB02504J.
https://pubs.rsc.org/en/content/articlelanding/2022/ob/d1ob02504j
Jinbiao Ying, Ting Liu, Yunyun Liu,* Jie-Ping Wan.* Base-Promoted Annulative Difluoromethylenation of Enaminones with BrCF2CO2Et toward 2,2-Difluorinated 2,3-Dihydrofurans. Organic Letters, 2022, 24(12), 2404-2408.
https://pubs.acs.org/doi/10.1021/acs.orglett.2c00671
Xiao Yun Chen,* Xiaotong Zhang, Jie-Ping Wan.* Recent advances in transition metal-free annulation toward heterocycle diversity based on the C–N bond cleavage of enaminone platform. Organic & Biomolecular Chemistry 2022, 20(12), 2356-2369. (Invited review)
https://pubs.rsc.org/en/content/articlelanding/2022/OB/D2OB00126H
Liu-Liang Mao,* An-Xi Zhou, Xian-Hong Zhu, Li-Xia Quan,* Fayun Chen, Jie-Ping Wan, Yin-Long Lai. Visible-light-mediated tandem phosphorylation/cyclization for the synthesis of phosphorylated oxindoles. Organic & Biomolecular Chemistry 2022, 20(6), 1196-1199.
https://pubs.rsc.org/en/content/articlelanding/2022/OB/D1OB02486H
Leiqing Fu, Jie-Ping Wan, Liyun Zhou, Yunyun Liu.* Copper-catalyzed C-H/N-H annulation of enaminones and alkynyl esters for densely substituted pyrrole synthesis. Chemical Communications, 2022, 58(11), 1808-1811.
https://pubs.rsc.org/en/Content/ArticleLanding/2022/CC/D1CC06768K
Haijin Guo, Lihong Tian, Yunyun Liu, Jie-Ping Wan.* DMSO as a C1 Source for [2 + 2 + 1] Pyrazole Ring Construction via Metal-Free Annulation with Enaminones and Hydrazines. Organic Letters, 2022, 24(1), 228-233.
https://pubs.acs.org/doi/10.1021/acs.orglett.1c03879
Yanhui Guo, Yunyun Liu, Jie-Ping Wan.* Amine-catalyzed synthesis of N2-sulfonyl 1,2,3-triazole in water and the tunable N2-H 1,2,3-triazole synthesis in DMSO via metal-free enamine annulation. Chinese Chemical Letters, 2022, 33(2), 855-858.
https://www.sciencedirect.com/science/article/abs/pii/S1001841721005763?via%3Dihub
2021年
Zhao Baoli, Yang Liangfeng, Cheng Kai, Zhou Liyun,* Wan Jie-Ping.* Visible Light Induced Oxidation of α-Diazo Esters for the Transition Metal-Free Synthesis of α-Keto Esters. Chinese Journal of Organic Chemistry 2021, 41(12), 4723-4737. (“绿色化学”特刊邀稿).
http://sioc-journal.cn/Jwk_yjhx/CN/10.6023/cjoc202111020
Tu Zhi, Zhao Baoli, Wan Jie-Ping, Wang Chaoli,* Yunyun Liu.* Aerobic Construction of 2-Acyl Benzoxazole by Tandem C-H Oxygenation and Oxazole Ring Formation. Chinese Journal of Organic Chemistry 2021, 41(12), 4780-4788. (“绿色化学”特刊邀稿).
http://sioc-journal.cn/Jwk_yjhx/CN/10.6023/cjoc202109029
Xiaobiao Lu, Xi Xiao, Ming Zhang, Changfeng Wan,* Haoqing Hou, Jieping Wan. Highly Selective Synthesis of 2-Substituted Pyrido[2,3-b]indole Derivatives Catalyzed by Iron Salts. Chinese Journal of Organic Chemistry 2021, 41(11), 4444-4449.
http://sioc-journal.cn/Jwk_yjhx/CN/10.6023/cjoc202107028
Tian Luo, Haozhi Wu, Li-hua Liao,* Jie-Ping Wan, Yunyun Liu.* Synthesis of 3,3-Dihalogenated 2-Aminochromanones via Tandem Dihalogenation and Cyclization of o-Hydroxyarylenaminones with NXS (X = Cl or Br). Journal of Organic Chemistry 2021, 86(21), 15785-15791.
https://pubs.acs.org/doi/full/10.1021/acs.joc.1c01851
Tao Zhang, Weijun Yao, Jie-Ping Wan,* Yunyun Liu.* Transition Metal-Free C(sp2)-H Dithiocarbamation and Chromone Annulation Cascade for 3-Dithiocarbamyl Chromone Synthesis. Advanced Synthesis & Catalysis 2021, 363(20), 4811-4816.
https://onlinelibrary.wiley.com/doi/10.1002/adsc.202100617
Yan Lin, Jun Jin, Chaoli Wang, Jie-Ping Wan, Yunyun Liu.* Electrochemical C-H Halogenations of Enaminones and Electron-Rich Arenes with Sodium Halide (NaX) as Halogen Source for the Synthesis of 3-Halochromones and Haloarenes. Journal of Organic Chemistry 2021, 86(17), 12378-12385.
https://pubs.acs.org/doi/10.1021/acs.joc.1c01347
Ting Liu, Jie-Ping Wan,* Yunyun Liu.* Metal-free enaminone C-N bond cyanation for stereoselective synthesis of (E)- and (Z)-β-cyano enones. Chemical Communications 2021, 57(72), 9112-9115.
https://pubs.rsc.org/en/content/articlelanding/2021/CC/D1CC03292E#!divAbstract
Shanghui Tian, Chaoli Wang, Jianhui Xia,* Jie-Ping Wan, Yunyun Liu.* Transition Metal-Free, Free-Radical Sulfenylation of the α-C(sp3)-H Bond in Arylacetamides and Its Application Toward 2-Thiomethyl Benzoxazoles Synthesis. Advanced Synthesis & Catalysis 2021, 363(19), 4627-4631.
https://onlinelibrary.wiley.com/doi/10.1002/adsc.202100816
Ting Liu, Li Wei, Baoli Zhao, Yunyun Liu,* Jie-Ping Wan.* Copper-Catalyzed Enaminone C(sp2)–N Bond Phosphonation for Stereoselective Synthesis of Alkenylphosphonates. Journal of Organic Chemistry 2021, 86(14), 9861
https://pubs.acs.org/doi/10.1021/acs.joc.1c00862
ChemistryViews报道链接：https://www.chemistryviews.org/details/news/11307991/Alkenylphosphonates_from_Enaminones.html
Zhongrong Xu, Leiqing Fu, Xia Fang, Bin Huang, Liyun Zhou, Jie-Ping Wan* Tunable Trifunctionalization of Tertiary Enaminones for the Regioselective and Metal-Free Synthesis of Discrete and Proximal Phosphoryl Nitriles. Organic Letters 2021, 23(13), 5049-5053.
https://pubs.acs.org/doi/10.1021/acs.orglett.1c01581
Xixi Zheng, Yunyun Liu, Jie-Ping Wan.* Metal-Free Synthesis of 1,2,3-Triazoles in Pure Water via the Enamine Modified Annulation Reactions with Tosyl Azide. Chinese Journal of Organic Chemistry 2021, 41(7), 2700-2706. (特邀论文)
http://sioc-journal.cn/Jwk_yjhx/CN/10.6023/cjoc202104053
Leiqing Fu, Yunyun Liu,* Jie-Ping Wan.* Pd-Catalyzed Triple-Fold C(sp2)–H Activation with Enaminones and Alkenes for Pyrrole Synthesis via Hydrogen Evolution. Organic Letter 2021, 23(11), 4363-4367.
https://pubs.acs.org/doi/10.1021/acs.orglett.1c01301
Qing Yu, Yunyun Liu, Jie-Ping Wan.* Metal-free C(sp2)-H perfluoroalkylsulfonylation and configuration inversion: stereoselective synthesis of α-perfluoroalkylsulfonyl E-enaminones. Chinese Chemical Letters 2021, 32(11), 3514-3517.
https://www.sciencedirect.com/science/article/abs/pii/S1001841721002795
Tian Luo, Shanghui Tian, Jie-Ping Wan,* Yunyun Liu*. Recent Advances in Transition Metal-Free Halogenation of C(sp2 )-H Bonds. Current Organic Chemistry 2021, 25(10), 1180-1193.
https://www.eurekaselect.com/190587/article
Mingqian Zhou, Yiqi Wang, Xiaoying Lin, Jieping Wan,* Chengping Wen.* Specific TLR4 Blocking Effect of a Novel 3,4-Dihydropyrimidinone Derivative. Frontiers in Pharmacology 2021, 11, 624059.
https://www.frontiersin.org/articles/10.3389/fphar.2020.624059/full
Lu Gan, Qing Yu, Yunyun Liu, Jie-Ping Wan.* Scissoring Enaminone C═C Double Bond by Free Radical Process for the Synthesis of α-Trifluoromethyl Ketones with CF3SO2Na. Journal of Organic Chemistry 2021, 86(1), 1231-1237.
https://pubs.acs.org/doi/10.1021/acs.joc.0c02431
2020年
Leiqing Fu, Zhongrong Xu, Jie-Ping Wan,* Yunyun Liu.* The Domino Chromone Annulation and a Transient Halogenation-Mediated C–H Alkenylation toward 3-Vinyl Chromones. Organic Letters, 2020, 22 (24), 9518-9523.
https://pubs.acs.org/doi/10.1021/acs.orglett.0c03548
CBG资讯报道：https://www.chembeango.com/zixun/53989
Deqing Hu, Lu Yang, Jie-Ping Wan.* Biaryl and atropisomeric biaryl aldehyde synthesis by one-step, metal-free benzannulation of aryl enals and propiolates. Green Chemistry 2020, 22(20), 6773-6777.
https://pubs.rsc.org/en/content/articlelanding/2020/gc/d0gc02806a#!divAbstract
Qing Yu, Yunyun Liu, Jie-Ping Wan.* Transition metal-free synthesis of 3-trifluoromethyl chromones via tandem C-H trifluoromethylation and chromone annulation of enaminones. Organic Chemistry Frontiers 2020, 7(18), 2770-2775.
https://pubs.rsc.org/en/content/articlelanding/2020/qo/d0qo00855a/unauth#!divAbstract
Shanghui Tian, Tian Luo, Yanping Zhu,* Jie-Ping Wan.* Recent advances in the diversification of chromones and flavones by direct C-H bond activation or functionalization. Chinese Chemical Letters 2020, 31(12) 3073-3082.
https://www.sciencedirect.com/science/article/abs/pii/S1001841720304423
Yi Li, Jie-Ping Wan.* Synthesis of 3-Alkylthiol Pyrazoles via Regioselective Annula-tion Reactions of Sulfonyl Hydrazines and Ketene Dithioacetals. Chinese Journal of Organic Chemistry 2020, 40(11), 3889-3894. (李毅，万结平.* 磺酰肼和二硫缩烯酮区域选择性环化反应合成3-烷硫基取代吡唑. 有机化学, 2020, 40(11), 3889-3894. 《有机化学》创刊四十周年专辑邀稿
http://sioc-journal.cn/Jwk_yjhx/CN/10.6023/cjoc202005026
Leiling Deng, Yunyun Liu, Yanping Zhu,* Jie-Ping Wan.* Transition Metal‐Free Annulation of Enamines and Tosyl Azide Toward N‐Heterocycle Fused and 5-Amino‐1,2,3-Triazoles. European Journal of Organic Chemistry 2020, (34), 5606-5609.
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202000938
Lu Gan, Li Wei, Jie-Ping Wan.* Catalyst‐Free Synthesis of α‐Diazoketones in Water by Microwave Promoted Enaminone C=C Double Bond Cleavage. ChemistrySelect 2020, 5(26), 7822-7825.
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202002247
Baoli Zhao, Yunyun Liu.* Step-Economical C–H Activation Reactions Directed by In Situ Amidation. Synthesis 2020, 52(21), 3211-3218.
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0040-1707124
Lu Yang, Jie-Ping Wan.* Ethyl lactate participated three-component dehydrogenative reactions: biomass feedstock in diversity oriented quinoline synthesis. Green Chemistry 2020, 22(10), 3074-3078.
https://pubs.rsc.org/en/content/articlelanding/2020/gc/d0gc00738b#!divAbstract
Yan Lin, Jie-Ping Wan, Yunyun Liu.* Synthesis of 3-halochromones with simple KX halogen sources enabled by in situ halide oxidation. New Journal of Chemistry 2020, 44(19), 8120-8124.
https://pubs.rsc.org/en/content/articlelanding/2020/nj/d0nj00825g#!divAbstract
Xixi Zheng, Yunyun Liu,* Jie-Ping Wan.* Advances in the Synthesis of N-Sulfonyl Amidines. Chinese Journal of Organic Chemistry 2020, 40(7), 1891-1900. (郑茜茜，刘云云*，万结平*. N-磺基脒类化合物合成研究进展. 有机化学 2020, 40(7), 1891-1900.)
http://sioc-journal.cn/Jwk_yjhx/CN/10.6023/cjoc202003019
Tian Luo, Jie-Ping Wan,* Yunyun Liu.* Toward C2-nitrogenated chromones by copper-catalyzed β-C(sp2)-H N-heteroarylation of enaminones. Organic Chemistry Frontiers, 2020, 7(9), 1107-1112.
https://pubs.rsc.org/en/content/articlelanding/2020/qo/d0qo00065e#!divAbstract
Lihong Tian, Jie-Ping Wan,* Shouri Sheng.* Transition Metal‐free C‐H Sulfonylation and Pyrazole Annulation Cascade for the Synthesis of 4‐Sulfonyl Pyrazoles. ChemCatChem 2020, 12(9), 2533-2537.
https://onlinelibrary.wiley.com/doi/abs/10.1002/cctc.202000244
王国栋(Guodong Wang)，郭艳辉(Yanhui Guo)，万结平(Jie-Ping Wan).* 无金属和氧化剂温和条件下碱促进的烯胺酮碳-碳双键断裂合成NH2-结构脒类化合物(Base-Promoted, Metal-and Oxidant-Free C=C Bond Cleavage in Enaminones for Ambient Synthesis of NH2-Amidines). 有机化学, 2020, 40(3), 645-650. (Chin. J. Org. Chem. 2020, 40(3), 645-650). 特邀论文，当期封面论文
http://journal15.magtechjournal.com/Jwk3_hxs/yjhx/CN/10.6023/cjoc201912018
Yunyun Liu,* Jin Xiong, Jie-Ping Wan.* Switchable Synthesis of α,α‐Dihalomethyl and α,α,α‐Trihalomethyl Ketones by Metal‐Free Decomposition of Enaminone C=C Double Bond. Advanced Synthesis & Catalysis, 2020, 362(4), 877-883.
https://onlinelibrary.wiley.com/doi/10.1002/adsc.201901234
Leiqing Fu, Xiaoji Cao, Jie-Ping Wan,* Yunyun Liu.* Synthesis of Enaminone‐Pd(II) Complexes and Their Application in Catalysing Aqueous Suzuki‐Miyaura Cross Coupling reactio. Chinese Journal of Chemistry 2020, 38(3), 254-258. Cover story
https://onlinelibrary.wiley.com/doi/abs/10.1002/cjoc.201900417
2019年
Xixi Zheng, Jie-Ping Wan.* The C=C Double Bond Decomposition Initiated by Enamine‐Azide Cycloaddition for Catalyst‐ and Additive‐Free Synthesis of N‐Sulfonyl Amidines. Advanced Synthesis & Catalysis 2019, 361(24), 5690-5694.
https://onlinelibrary.wiley.com/doi/10.1002/adsc.201901054
Leiling Deng, Xiaoji Cao, Yunyun Liu,* Jie-Ping Wan.* In-Water Synthesis of 5-Thiolated 1,2,3-Triazoles From β-Thioenaminones by Diazo Transfer Reaction. Journal of Organic Chemistry 2019, 84, 14179-14186.
https://pubs.acs.org/doi/10.1021/acs.joc.9b01817
Zhi Tu, Yi Du, Xiaoji Cao, Yunyun Liu.* Tunable Single and Double γ‐C‐H Arylation of Phenylacetamides Directed by o‐Aminophenols. Advanced Synthesis & Catalysis 2019, 361, 4989-4991.
Lihong Tian, Yanhui Guo, Li Wei, Jie-Ping Wan,* Shouri Sheng.* Thermo‐Induced Free Radical Cleavage of Enaminone C=C Double Bond for α‐Acyloxyl Ketone Synthesis. Asian Journal of Organic Chemistry 2019, 8, 1484-1489.
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajoc.201900373
Qing Yu, Yating Zhang, Jie-Ping Wan*. Ambient and aerobic carbon-carbon bond cleavage toward α-ketoester synthesis by transition-metal-free photocatalysis. Green Chemistry 2019, 21(12), 3436-3441.
https://pubs.rsc.org/en/content/articlelanding/2019/gc/c9gc01357a#!divAbstract
Highlighted in ChemBeanGo: https://www.chembeango.com/zixun/42588
王昱赟，刘云云.* 无金属催化的吡啶C2位碳-氢键胺甲酰化反应合成吡啶甲酰胺. 化学学报, 2019, 77(5), 418-421. (当期封面)
http://sioc-journal.cn/Jwk_hxxb/CN/10.6023/A19020061
Jin Xiong, Guofeng Zhong, Yunyun Liu.* Domino Reactions Initiated by Copper‐Catalyzed Aryl‐I Bond Thiolation For the Switchable Synthesis of 2,3‐Dihydrobenzothiazinones and Benzoisothiazolones. Advanced Synthesis & Catalysis 2019, 361(3), 550-555.
https://onlinelibrary.wiley.com/doi/10.1002/adsc.201801221
Leiqing Fu, Jie-Ping Wan.* Recent Advances In the C3‐Functionalized Chromones Synthesis By the Featured Tandem C‐H Elaboration and Chromone Annulation of Enaminones. Asian Journal of Organic Chemistry 2019, 8, 767-776. (Invited Review)
https://onlinelibrary.wiley.com/doi/10.1002/ajoc.201900196
Jie-Ping Wan,* Zhi Tu,# Yuyun Wang.# (#equal contribution) Transient and Recyclable Halogenation Coupling (TRHC) for Isoflavonoid Synthesis with Site Selective Arylation. Chemistry-A European Journal 2019, 25(28), 6907-6910.
https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201901025
Highlighted in ChemBeanGo: https://www.chembeango.com/zixun/41539c5
Yanhui Guo, Guodong Wang, Li Wei, Jie-Ping Wan.* Domino C-H Sulfonylation and Pyrazole Annulation for Fully Substituted Pyrazole Synthesis in Water Using Hydrophilic Enaminones. Journal of Organic Chemistry 2019, 84(5), 2984-2990.
https://pubs.acs.org/doi/10.1021/acs.joc.8b02897
Yong Gao, Yunyun Liu, Jie-Ping Wan.* Visible Light-Induced Thiocyanation of Enaminone C–H Bond to Access Polyfunctionalized Alkenes and Thiocyano Chromones. Journal of Organic Chemistry 2019, 84(4), 2243-2251.
https://pubs.acs.org/doi/10.1021/acs.joc.8b02981
Lu Gan,# Yong Gao,# (#equal contribution) Li Wei, Jie-Ping Wan.* Synthesis of α-Keto Thioamides by Metal-Free C═C Bond Cleavage in Enaminones Using Elemental Sulfur. Journal of Organic Chemistry 2019, 84(2), 1064-1069.
https://pubs.acs.org/doi/10.1021/acs.joc.8b02670
Highlighted in Organic Chemistry Portal: https://www.organic-chemistry.org/abstracts/lit6/673.shtm
2018年
Jiarui Sun, Xiangsheng Cheng, John Kamanda Mansaray, Weihong Fei, Jieping Wan,* Weijun Yao.*
A copper-catalyzed three component reaction of aryl acetylene, sulfonyl azide and enaminone to form iminolactone via 6π electrocyclization. Chemical Communications 2018, 54(99), 13953-13956.
https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc06868b#!divAbstract
Shuo Cao, Yunyun Liu, Changfeng Hu, Chengping Wen,* Jie-Ping Wan.* Alkyl Propiolates Participated [3+2] Annulation for the Switchable Synthesis of 1,5‐ and 1,4‐Disubstituted 1,2,3‐Triazoles Containing Ester Side Chain. ChemCatChem 2018, 10(21), 5007-5011.
https://onlinelibrary.wiley.com/doi/10.1002/cctc.201801366
Qing Yu, Yiming Yang, Jie-Ping Wan, Yunyun Liu.* Copper-Catalyzed C5–H Sulfenylation of Unprotected 8-Aminoquinolines Using Sulfonyl Hydrazides. Journal of Organic Chemistry 2018, 83(18), 11385-11391.
https://pubs.acs.org/doi/10.1021/acs.joc.8b01658
Yanhui Guo, Yunfeng Xiang, Li Wei, Jie-Ping Wan.* Thermoinduced Free-Radical C–H Acyloxylation of Tertiary Enaminones: Catalyst-Free Synthesis of Acyloxyl Chromones and Enaminones. Organic Letters 2018, 20(13), 3971-3974.
https://pubs.acs.org/doi/10.1021/acs.orglett.8b01536
Highlighted in Organic Chemistry Portal: https://www.organic-chemistry.org/abstracts/lit6/407.shtm
Highlighted in ChemBeanGo: https://www.chembeango.com/zixun/24606
Lu Yang, Li Wei, Jie-Ping Wan.* Redox neutral [4+2] benzannulation of dienals and tertiary enaminones for benzaldehyde synthesis. Chemical Communications 2018, 54(54), 7475-7478.
https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc03514h#!divAbstract
Yi Du, Yunyun Liu,* Jie-Ping Wan.* Copper-Catalyzed One-Pot N-Acylation and C5–H Halogenation of 8-Aminoquinolines: The Dual Role of Acyl Halides. Journal of Organic Chemistry 2018, 83(6), 3403-3408.
https://pubs.acs.org/doi/10.1021/acs.joc.8b00068
Lu Yang, Yuwei Wu, Yiming Yang, Chengping Wen,* Jie-Ping Wan.* Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide. Beilstein Journal of Organic Chemistry 2018, 14, 2348-2353.
https://www.beilstein-journals.org/bjoc/articles/14/210
2017年
Yong Gao, Changfeng Hu, Chengping Wen,* Jie-Ping Wan.* Tunable Synthesis of Disulfide-Functionalized Enaminones and 1,4-Thiazines via the Reactions of Enaminones and β-Aminoethanethiol. ACS Omega 2017, 2(11), 7784-7789. (Invited contribution)
https://pubs.acs.org/doi/10.1021/acsomega.7b01422
Yi Li, Xiaoji Cao, Yunyun Liu, Jie-Ping Wan.* Regioselective three-component synthesis of 2,3-disubstituted quinolines via the enaminone modified Povarov reaction. Organic & Biomolecular Chemistry 2017, 15(45), 9585-9589.
https://pubs.rsc.org/en/content/articlelanding/2017/ob/c7ob02411h#!divAbstract
Jie-Ping Wan,* Lu Gan, Yunyun Liu.* Transition metal-catalyzed C–H bond functionalization in multicomponent reactions: a tool toward molecular diversity. Organic & Biomolecular Chemistry 2017, 15(43), 9031-9043. (invited review)
https://pubs.rsc.org/en/content/articlelanding/2017/ob/c7ob02011b#!divAbstract
Yunyun Liu,* Yi Zhang, Jie-Ping Wan.* Multicomponent Synthesis of Diverse o-Arylated Benzamides via o-Aminophenol (OAP) Directed C(sp2)-H Arylation. Journal of Organic Chemistry 2017, 82(17), 8950-8957.
https://pubs.acs.org/doi/10.1021/acs.joc.7b01375
Yong Gao, Li Wei, Yunyun Liu,* Jie-Ping Wan.* Iodine-mediated synthesis of sulfur-bridged enaminones and chromones via double C(sp2)–H thiolation. Organic & Biomolecular Chemistry 2017, 15(21), 4631-4634.
https://pubs.rsc.org/en/content/articlelanding/2014/OB/C7OB00619E#!divAbstract
Shanshan Zhong, Yunyun Liu, Xiaoji Cao, Jie-Ping Wan.* KIO3‐Catalyzed Domino C(sp2)−H Bond Sulfenylation and C−N Bond Oxygenation of Enaminones toward the Synthesis of 3‐Sulfenylated Chromones. ChemCatChem 2017, 9(3), 465-468.
https://onlinelibrary.wiley.com/doi/full/10.1002/cctc.201601273
Jie-Ping Wan,* Shanshan Zhong, Yanhui Guo, Li Wei. Iodine‐Mediated Domino C(sp2)–H Sulfonylation/Annulation of Enaminones and Sulfonyl Hydrazines for the Synthesis of 3‐Sulfonyl Chromones. European Journal of Organic Chemistry 2017, (30), 4401-4404.
https://onlinelibrary.wiley.com/doi/full/10.1002/ejoc.201700910
Yong Gao, Li Wei, Yunyun Liu, Jie-Ping Wan.* Synthesis of enaminones containing diverse N,N-disubstitution via simple transamination: a study with sustainable catalyst-free operation. Research on Chemical Intermediates 2017, 43(10), 5547-5555.
https://link.springer.com/article/10.1007/s11164-017-2946-z
Yi Li, Li Wei, Jie-Ping Wan,* Chengping Wen.* Water-acetic acid mediated chemoselective synthesis of pyrazolines via multimolecular domino reactions of enaminones and sulfonyl hydrazines. Tetrahedron 2017, 73(16), 2323-2328.
https://www.sciencedirect.com/science/article/pii/S0040402017302454
2016年
https://pubs.acs.org/doi/abs/10.1021/acs.orglett.6b02975
Yunyun Liu,* Yi Zhang, Xiaoji Cao, Jie-Ping Wan. Synthesis of β-arylated alkylamides via Pd-catalyzed one-pot installation of a directing group and C(sp3)–H arylation. 2016, 12, 1122-1126.
https://www.beilstein-journals.org/bjoc/articles/12/108
Jie-Ping Wan,* Deqing Hu, Ying Liu, Luyao Li, Chengping Wen.* Copper-catalyzed intramolecular oxidative amination of enaminone C–H bond for the synthesis of imidazo[1,2-a]pyridines. Tetrahedron Letters 2016, 57(26), 2880-2883.
https://www.sciencedirect.com/science/article/pii/S0040403916305949
Li Wei, Xuwen Chen, Yunyun Liu, Jie-Ping Wan.* Recent Advances in Organic Synthesis Employing Ethyl Lactate as Green Reaction Medium. Chinese Journal of Organic Chemistry 2016, 36(5), 954-961.
http://sioc-journal.cn/Jwk_yjhx/CN/abstract/abstract345393.shtml
Jie-Ping Wan,* Yanfeng Jing, Changfeng Hu, Shouri Sheng.* Metal-Free Synthesis of Fully Substituted Pyridines via Ring Construction Based on the Domino Reactions of Enaminones and Aldehydes. Journal of Organic Chemistry 2016, 81(15), 6826-6831.
https://pubs.acs.org/doi/abs/10.1021/acs.joc.6b01149
Jie-Ping Wan,* Deqing Hu, Feicheng Bai, Li Wei, Yunyun Liu.* Stereoselective Z-halosulfonylation of terminal alkynes using sulfonohydrazides and CuX (X = Cl, Br, I). RSC Advances 2016, 6(77), 73132-73135.
https://pubs.rsc.org/en/content/articlelanding/2016/ra/c6ra13737g#!divAbstract
Deqing Hu, Feicheng Bai, Jie-Ping Wan,* Yunyun Liu.* Copper‐Catalyzed Hydrosulfonylation of Alkynes Employing Sulfonohydrazides toward the Synthesis of Vinyl Sulfones. Chinese Journal of Chemistry 2016, 34(10), 1053-1057.
https://onlinelibrary.wiley.com/doi/abs/10.1002/cjoc.201600337
Xuwen Chen, Changfen Hu, Jie-Ping Wan, Yunyun Liu.* Dichloromethane as methylene donor for the one-pot synthesis of bisaryloxy methanes via Williamson etherification and Suzuki coupling. Tetrahedron Letters 2016, 57(46), 5116-5119.
https://www.sciencedirect.com/science/article/pii/S0040403916313260
Yong Gao, Changfeng Hu, Jie-Ping Wan,* Chengping Wen.* Metal-free cascade reactions of aldehydes and primary amines for the synthesis of 1,3,4-trisubstituted pyrroles. Tetrahedron Letters, 2016, 57(43), 4854-4857.
https://www.sciencedirect.com/science/article/pii/S0040403916312321
Shanshan Zhong, Yu Lu, Yan Zhang, Yunyun Liu, Jie-Ping Wan.* Synthesis of β,β-diaryl propiophenones via palladium-catalyzed domino arylboronation, elimination and enone hydroarylation of enaminones. Organic & Biomolecular Chemistry 2016, 14(26), 6270-6273.
https://pubs.rsc.org/en/content/articlelanding/2014/ob/c6ob01038e#!divAbstract
Jie-Ping Wan,* Yong Gao, Li Wei.* Recent Advances in Transition‐Metal‐Free Oxygenation of Alkene C=C Double Bonds for Carbonyl Generation. Chemistry-An Asian Journal 2016, 11(15), 2092-2102. (invited review)
https://onlinelibrary.wiley.com/doi/full/10.1002/asia.201600671
Jie-Ping Wan, Yi Li, Yunyun Liu.* Annulation based on 8-aminoquinoline assisted C–H activation: an emerging tool in N-heterocycle construction. Organic Chemistry Frontiers 2016, 3(6), 768-772.
https://pubs.rsc.org/en/content/articlelanding/2016/qo/c6qo00077k/unauth#!divAbstract
Jie-Ping Wan,* Shanshan Zhong, Lili Xie, Xiaoji Cao, Yunyun Liu, Li Wei. KIO3-Catalyzed Aerobic Cross-Coupling Reactions of Enaminones and Thiophenols: Synthesis of Polyfunctionalized Alkenes by Metal-Free C–H Sulfenylation. Organic Letters 2016, 18(3), 584-587.
https://pubs.acs.org/doi/abs/10.1021/acs.orglett.5b03608
Jie-Ping Wan,* Youyi Zhou, Yunyun Liu, Shouri Sheng.* Metal-free oxidative carbonylation on enaminone C![[double bond, length as m-dash]](https://www.rsc.org/images/entities/h2_char_e001.gif)
C bond for the cascade synthesis of benzothiazole-containing vicinal diketones. Green Chemistry 2016, 18(2), 402-405.
https://pubs.rsc.org/en/content/articlelanding/2016/gc/c5gc01821h#divAbstract
Jie-Ping Wan,* Yunfang Lin, Xiaoji Cao, Yunyun Liu. Copper-catalyzed, hypervalent iodine mediated C=C bond activation of enaminones for the synthesis of α-keto amides. Chemical Communications 2016, 52(6), 1270-1273.
https://pubs.rsc.org/en/content/articlelanding/2016/cc/c5cc08843g#!divAbstract
Yunyun Liu, Bin Huang, Xiaoji Cao, Jie-Ping Wan.* Tunable Di‐ and Mono‐γ‐C−H Arylation of Phenylacetamides by Palladium‐Catalyzed Domino Reactions. ChemCatChem 2016, 8(8), 1470-1473.
https://onlinelibrary.wiley.com/doi/full/10.1002/cctc.201600039
Jie-Ping Wan,* Yong Gao. Domino Reactions Based on Combinatorial Bond Transformations in Electron‐Deficient Tertiary Enamines. the Chemical Record 2016, 16(3), 1164-1177. (invited personal account)
https://onlinelibrary.wiley.com/doi/abs/10.1002/tcr.201500296
2015年
Shuo Cao, Shanshan Zhong, Luoting Xin, Jie-Ping Wan,* Chengping Wen.* Visible‐Light‐Induced CC Bond Cleavage of Enaminones for the Synthesis of 1,2‐Diketones and Quinoxalines in Sustainable Medium. ChemCatChem 2015, 7(9), 1478-1482.
https://onlinelibrary.wiley.com/doi/abs/10.1002/cctc.201500139
Jie-Ping Wan,* Yanfeng Jing. Recent advances in copper-catalyzed C–H bond amidation. Beilstein Journal of Organic Chemistry 2015, 11, 2209-2222. (invited review)
https://www.beilstein-journals.org/bjoc/articles/11/240
Jie-Ping Wan,* Shuo Cao, Yunyun Liu. A Metal- and Azide-Free Multicomponent Assembly toward Regioselective Construction of 1,5-Disubstituted 1,2,3-Triazoles. Journal of Organic Chemistry 2015, 80(18), 9028-9033.
https://pubs.acs.org/doi/10.1021/acs.joc.5b01121
Jie-Ping Wan,* Shanshan Zhong, Yunyun Liu. Enaminone-Based Three-Component Reactions for the Diastereoselective Synthesis of Fused Tetrahydropyridines. Synthesis 2015, 47(22), 3611-3617.
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0034-1378875
.Yanfeng Jing, Jiaojiao Meng, Yunyun Liu,* Jie-Ping Wan.* Direct Three‐Component Synthesis of α‐Cyano Acrylates Involving Cascade Knoevenagel Reaction and Esterification. Chinese Journal of Chemistry 2015, 33(10), 1194-1198.
https://onlinelibrary.wiley.com/doi/abs/10.1002/cjoc.201500420
Deqing Hu, Yunyun Liu, Jie-Ping Wan.* An organocatalytic multi-molecular cascade reaction for the synthesis of acetate functionalized 1,4-dihydropyridines. Tetrahedron 2015, 71(36), 6094-6098.
https://www.sciencedirect.com/science/article/pii/S0040402015009989
Bing Huang, Deqing Hu, Jing Wang, Jie-Ping Wan, Yunyun Liu.* Copper-catalyzed one-pot tandem reactions toward the synthesis of indoles using o-iodoanilines, acyl chlorides, and Wittig reagents. Tetrahedron Letters 2015, 56(20), 2551-2554.
https://www.sciencedirect.com/science/article/pii/S0040403915006152
Yi Zhang, Yunyun Liu, Jie-Ping Wan.* Copper-catalyzed three-component reactions of phenols, acyl chlorides and Wittig reagents for the synthesis of β-aryloxyl acrylates. New. J. Chem. 2015, 39(3), 1567-1569.
https://pubs.rsc.org/en/content/articlelanding/2015/nj/c4nj02010c#!divAbstract
Yunyun Liu, Yi Zhang, Meiying Huang, Jie-Ping Wan.* Step economical synthesis of o-aryl benzamides via C–H activation relayed by the in situ installation of directing group: a multicomponent method. RSC Adv. 2015, 5(57), 46192-46196.
https://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra09078d#!divAbstract
Shuo Cao, Luoting Xin, Yunyun Liu, Jie-Ping Wan,* Chengping Wen.* Regioselective three-component reactions of enaminones, 2-aminopyridines and enals for the synthesis of 1,2-dihydropyridines. RSC Adv. 2015, 5(35), 27372-27374.
https://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra01901j#!divAbstract
2014年
Jie-Ping Wan,* Yunfang Lin, Qing Huang, Yunyun Liu. Diastereoselective Construction of Tetrahydropyridine Fused Bicyclic Structures via Three-Component Domino Reaction. Journal of Organic Chemistry 2014, 79(15), 7232-7238.
https://pubs.acs.org/doi/abs/10.1021/jo501292q
Yunyun Liu,* Hang Wang, Jie-Ping Wan.* Copper-Catalyzed, C–C Coupling-Based One-Pot Tandem Reactions for the Synthesis of Benzofurans Using o-Iodophenols, Acyl Chlorides, and Phosphorus Ylides. Journal of Organic Chemistry 2014, 79(21), 10599-10604.
https://pubs.acs.org/doi/abs/10.1021/jo5017508
Jie-Ping Wan,* Youyi Zhou, Shuo Cao. Domino Reactions Involving the Branched C–N and C═C Cleavage of Enaminones Toward Pyridines Synthesis. Journal of Organic Chemistry 2014, 79(20), 9872-9877.
https://pubs.acs.org/doi/abs/10.1021/jo5018266
Jie-Ping Wan,* Youyi Zhou, Kezhi Jiang, Hongyan Ye. Thioacetamide as an Ammonium Source for Multicomponent Synthesis of Pyridines from Aldehydes and Electron-Deficient Enamines or Alkynes. Synthesis 2014, 46(23), 3256-3262.
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0034-1378635
https://www.sciencedirect.com/science/article/pii/S0040402014012812
Jie-Ping Wan,* Hang Wang, Yunyun Liu, Hanfeng Ding.* Synthesis of 2-Vinylbenzofurans via the Copper-Catalyzed Multicomponent Reactions Involving an Oxa-Michael/Arylation/Vinylation Cascade. Organic Letters 2014, 16(19), 5160-5163.
https://pubs.acs.org/doi/abs/10.1021/ol502506g
曹硕，景艳锋，刘云云，万结平*. 基于缺电子烯胺交叉氨化过程的多组分反应研究进展. 有机化学 2014, 34(5), 876-885.
http://sioc-journal.cn/Jwk_yjhx/CN/abstract/abstract343751.shtml
Jieping Wan,* Youyi Zhou, Yunyun Liu, Zheng Fang, Chengping Wen.* Multicomponent Reactions for Diverse Synthesis of N‐Substituted and NH 1,4‐Dihydropyridines. Chinese Journal of Chemistry 2014, 32(3), 219-226.
https://onlinelibrary.wiley.com/doi/10.1002/cjoc.201300918
Jie-Ping Wan,* Yunfang Lin, Yunyun Liu. Catalytic Asymmetric Biginelli Reaction for the Enantioselective Synthesis of 3,4- Dihydropyrimidinones (DHPMs). Current Organic Chemistry 2014, 18(6), 687-699.
http://www.eurekaselect.com/121608/article
Yunyun Liu,* Yi Zhang, Changfeng Hu, Jie-Ping Wan, Chengping Wen.* Synthesis of 3-sulfenylated indoles by a simple NaOH promoted sulfenylation reaction. RSC Advances 2014, 4(67), 35528-35530.
https://pubs.rsc.org/en/content/articlelanding/2014/ra/c4ra05206d#!divAbstract
Jie-Ping Wan,* Yanfeng Jing, Yunyun Liu, Shouri Sheng.* Metal-free synthesis of cyano acrylates via cyanuric chloride-mediated three-component reactions involving a cascade consists of Knoevenagel condensation/cyano hydration/esterification. RSC Advances 2014, 4(109), 63997-64000.
https://pubs.rsc.org/en/content/articlelanding/2014/ra/c4ra13826k#!divAbstract
Yunyun Liu,* Bin Huang, Xiaoji Cao, Dan Wu, Jie-Ping Wan. Synthesis of heteroaryl containing sulfides via enaminone ligand assisted, copper-catalyzed C–S coupling reactions of heteroaryl thiols and aryl halides. RSC Advances 2014, 4(71), 37733-37737.
https://pubs.rsc.org/en/content/articlelanding/2014/ra/c4ra07187e#!divAbstract
Jie-Ping Wan,* Yunfang Lin, Kaikai Hu, Yunyun Liu. Secondary amine-initiated three-component synthesis of 3,4-dihydropyrimidinones and thiones involving alkynes, aldehydes and thiourea/urea. Beilstein Journal of Organic Chemistry 2014, 10, 287-292.
https://www.beilstein-journals.org/bjoc/articles/10/25
Jie-Ping Wan,* Yunfang Lin, Kaikai Hu, Yunyun Liu.* Metal-free synthesis of 1,3,5-trisubstituted benzenes by the cyclotrimerization of enaminones or alkynes in water. RSC Advances 2014, 4(39), 20499-20505.
https://pubs.rsc.org/en/content/articlelanding/2014/ra/c4ra00475b#!divAbstract
Yunyun Liu,* Hang Wang, Jida Zhang, Jie-Ping Wan, Chengping Wen.* Disulfides as efficient thiolating reagents enabling selective bis-sulfenylation of aryl dihalides under mild copper-catalyzed conditions. RSC Advances, 2014, 4(37), 19472-19475.
https://pubs.rsc.org/en/content/articlelanding/2014/ra/c4ra02935f#!divAbstract
2013年
Yunyun Liu, Hang Wang, Xiaoji Cao, Zheng Fang, Jie-Ping Wan.* Copper-Catalyzed Selective Single Arylsulfanylation of Aryl Diiodides with Aryl Thiols. Synthesis 2013, 45(21), 2077-2982.
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0033-1338525
Yunyun Liu, Hang Wang, Jie-Ping Wan.* Recent Advances in Diversity Oriented Synthesis through Isatin‐based Multicomponent Reactions. Asian Journal of Organic Chemistry 2013, 2(5), 374-386.
https://onlinelibrary.wiley.com/doi/full/10.1002/ajoc.201200180
https://pubs.rsc.org/en/content/articlelanding/2013/ra/c3ra42915f#!divAbstract
Jie-Ping Wan,* Rihui Zhou, Yunyun Liu, Mingzhong Cai. A “byproduct–intermediate–product” recycling strategy for multicomponent synthesis of 1,4-dihydropyridines. RSC Advances 2013, 3(7), 2477-2482.
https://pubs.rsc.org/en/content/articlelanding/2013/ra/c2ra23277d#!divAbstract
Yunyun Liu, Rihui Zhou, Jie-Ping Wan.* Water-Promoted Synthesis of Enaminones: Mechanism Investigation and Application in Multicomponent Reactions. Synthetic Communications 2013, 43(18), 2475-2483.
https://www.tandfonline.com/doi/full/10.1080/00397911.2012.715712
2010-2012年
Yunyun Liu, Jie-Ping Wan.* Advances in Copper‐Catalyzed CC Coupling Reactions and Related Domino Reactions Based on Active Methylene Compounds. Chemistry-An Asian Journal 2012, 7(7), 1488-1501.
https://onlinelibrary.wiley.com/doi/abs/10.1002/asia.201101063
Jie-Ping Wan,* Yunyun Liu. Recent advances in new multicomponent synthesis of structurally diversified 1,4-dihydropyridines. RSC Advances 2012, 2(26), 9763-9777.
https://pubs.rsc.org/en/content/articlelanding/2012/ra/c2ra21406g#!divAbstract
J.-P. Wan, Y. Pan.* Recent Advance in the Pharmacology of Dihydropyrimidinone. Mini-Reviews in Medicinal Chemistry 2012, 12(4), 337-349.
http://www.eurekaselect.com/97342/article
Jie-Ping Wan, Charles C. J. Loh, Fangfang Pan, Dieter Enders.* Enantioselective organocatalytic domino synthesis of tetrahydropyridin-2-ols. Chemical Communications 2012, 48(80), 10049-10051.
https://pubs.rsc.org/en/content/articlelanding/2012/cc/c2cc35644a#!divAbstract
Jie-Ping Wan,* Chunping Wang, Yunyun Liu. Chemo‐selective copper‐catalyzed C‐O coupling reactions of phenols with aryl/vinyl halides using enaminone as efficient ligand. Applied Organometallic Chemistry 2012, 26(8), 445-447.
https://onlinelibrary.wiley.com/doi/full/10.1002/aoc.2886
Jie-Ping Wan, Chunping Wang, Rihui Zhou, Yunyun Liu.* Sustainable H2O/ethyl lactate system for ligand-free Suzuki–Miyaura reaction. RSC Advances 2012, 2(23), 8789-8792.
https://pubs.rsc.org/en/content/articlelanding/2012/ra/c2ra21632a#!divAbstract
Jie-Ping Wan,* Yunyun Liu. Multicomponent Reactions Promoted by Organosilicon Reagents. Current Organic Chemistry 2011, 15(16), 2758-2773.
http://www.eurekaselect.com/74636/article
Jie-Ping Wan,* Chunping Wang, Yunyun Liu. Direct synthesis of enaminone functionalized biaryl ethers by CuI-catalyzed O-arylation of enaminone functionalized phenols. Organic & Biomolecular Chemisty 2011, 9(19), 6481-6483.
https://pubs.rsc.org/en/content/articlelanding/2011/ob/c1ob05947e#!divAbstract
Yunyun Liu,* Jie-Ping Wan. Tandem reactions initiated by copper-catalyzed cross-coupling: A new strategy towards heterocycle synthesis. Organic & Biomolecular Chemisty 2011, 9(20), 6873-6894.
https://pubs.rsc.org/en/content/articlelanding/2011/ob/c1ob05769c#!divAbstract
Jie-Ping Wan.* Yunyun Liu. Synthesis of Dihydropyrimidinones and Thiones by Multicomponent Reactions: Strategies Beyond the Classical Biginelli Reaction. Synthesis 2010, (23), 3943-3953.
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0030-1258290
![Graphical abstract: Redox neutral [4+2] benzannulation of dienals and tertiary enaminones for benzaldehyde synthesis](https://pubs.rsc.org/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C8CC03514H "Graphical abstract")
![Graphical abstract: Metal-free oxidative carbonylation on enaminone C [[double bond, length as m-dash]] C bond for the cascade synthesis of benzothiazole-containing vicinal diketones](https://pubs.rsc.org/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C5GC01821H "Graphical abstract")
![Graphical abstract: Copper-catalyzed, hypervalent iodine mediated C [[double bond, length as m-dash]] C bond activation of enaminones for the synthesis of α-keto amides](https://pubs.rsc.org/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C5CC08843G "Graphical abstract")
