近期成果：
27. Construction of P-stereogenic Centres via Palladium/Chiral Norbornene Cooperative Catalysis
Jinxiang Ye, Yiming You, Dekang Xu, Shuang Deng, Lifang Qi, Chang Liu, Cheng-Cheng Liu, Hengjiang Cong, Peng Wang, Hong-Gang Cheng, Qianghui Zhou*. CCS Chem., 2024, xx, xxxx. DOI:10.31635/ccschem.024.202404858
26. Advances in the synthesis of C19-hydroxylated steroids
Dongkai Wang†, Lan Zhou†, Fuzhen Song, Qianghui Zhou*. Green Synth. Catal., 2024, xx, xxxx. DOI:10.1016/j.gresc.2024.09.004
25. Enantioconvergent synthesis of chiral fluorenols from racemic secondary alcohols via Pd(II)/chiral norbornene cooperative catalysis
Bo Ding†, Qilin Xue, Han Wei, Jiangwei Chen, Ze-Shui Liu, Hong Gang Cheng, Hengjiang Cong, Jianting Tang and Qianghui Zhou*. Chem. Sci. 2024, 15, 7975-7981. DOI: 10.1039/d4sc01004c
24. Transition-Metal Catalyzed C−H Alkylation Using Epoxides as Alkylating Reagents Ze-Shui Liu*, Danni Wang, Hong-Gang Cheng*,
Qianghui Zhou. ChemCatChem. 2024, e202301764. DOI: 10.1002/cctc.202301764
23. Synthesis of Planar Chiral Ferrocenes via Enantioselective Remote C–H Activation Lan Zhou†, Hong-Gang Cheng†*, Lisha Li, Kevin Wu, Jing Hou, Chengkang Jiao, Shuang Deng, Zirui Liu, Jin-Quan Yu* and Qianghui Zhou*. Nat. Chem. 2023, 15, 815-823. DOI: 10.1038/s41557-023-01176-3
22. Chemoenzymatic Synthesis of C14-functionalized Steroids Fuzhen Song†, Mengmeng Zheng†, Junlin Wang, Huanhuan Liu, Zhi Lin, Benben Liu, Zixin Deng, Hengjiang Cong, Qianghui Zhou* and Xudong Qu*. Nat. Synth. 2023, 2, 729–739. DOI: 10.1038/s44160-023-00280-z.
21. Construction of Axially Chiral Biaryls via Atroposelective ortho-C–H Arylation of Aryl Iodides Ze-Shui Liu†, Shuang Deng†, Qianwen Gao, Yu Hua, Hong-Gang Cheng, Xiaotian Qi* and Qianghui Zhou*. ACS Catal. 2023, 13, 2968–2980.
DOI: 10.1021/acscatal.2c06310.
20. Benzo-Fused-Ring Toolbox Based on Palladium/Norbornene Cooperative Catalysis: Methodology Development and Applications in Natural Product Synthesis. Hong-Gang Cheng† , Shihu Jia† and Qianghui Zhou*. Acc. Chem. Res. 2023, 56, 573–591. DOI: 10.1021/acs.accounts.2c00781
19. Enantioselective Assembly of Ferrocenes with Axial and Planar Chiralities via Palladium/Chiral Norbornene Cooperative Catalysis.Jinxiang Ye†, Lisha Li†, Yiming You, Chengkang Jiao, Ziyang Cui, Yabin Zhang, Shihu Jia, Hengjiang Cong, Shanshan Liu, Hong-Gang Cheng* and Qianghui Zhou*. JACS Au 2023, 3, 384–390. DOI:10.1021/jacsau.2c00630
18. From N–H Nitration to Controllable Aromatic Mononitration and Dinitration─The Discovery of a Versatile and Powerful N-Nitropyrazole Nitrating Reagent. Tao Yang, Xiaoqian Li, Shuang Deng, Xiaotian Qi, Hengjiang Cong, Hong-Gang Cheng, Liangwei Shi*, Qianghui Zhou*, and Lin Zhuang*. JACS Au 2022, 2, 2152–2161. DOI: 10.1021/jacsau.2c00413
17. A Modular Approach for Diversity-Oriented Synthesis of 1,3-trans -Disubstituted Tetrahydroisoquinolines: Seven-Step Asymmetric Synthesis of Michellamines B andC. Miao Bai, Shihu Jia, Jingyang Zhang, Hong-Gang Cheng, Hengjiang Cong, Shanshan Liu, Zhiqian Huang, Yaoguo Huang, Xiaoming Chen, Qianghui Zhou*.Angew. Chem. Int. Ed. 2022, e202205245. DOI:org/10.1002/anie.202205245
16. Catalytic Synthesis of Atropisomeric o-Terphenyls with 1,2-Diaxes via Axial-to-Axial Diastereoinduction. Qianwen Gao, Chenggui Wu, Shuang Deng, Lisha Li, Ze-Shui Liu, Yu Hua, Jinxiang Ye, Chang Liu, Hong-Gang Cheng, Hengjiang Cong, Yinchun Jiao, and Qianghui Zhou*. J. Am. Chem. Soc. 2021, 143, 7253-7260. DOI: 10.1021/jacs.1c02405
15. Diversity-oriented functionalization of 2-pyridones and uracils. Yong Shang†, Chenggui Wu†, Qianwen Gao, Chang Liu, Lisha Li, Xinping Zhang, Hong-Gang Cheng, Shanshan Liu, Qianghui Zhou*. Nat. Commun. 2021, 12, 2988.
14. An axial-to-axial chirality transfer strategy for atroposelective construction of C–N axial chirality. Ze-Shui Liu†, Pei-Pei Xie†, Yu Hua, Chenggui Wu, Yuanyuan Ma, Jiangwei, Chen, Hong-Gang Cheng, Xin Hong*, Qianghui Zhou*. Chem. 2021, 7, 1917-1932. DOI:10.1016/j.chempr.2021.04.005
13. Kinetic Resolution of Tertiary Benzyl Alcohols via Palladium/Chiral Norbornene Cooperative Catalysis. Yu Hua†, Ze-Shui Liu†, Pei-Pei Xie, Bo Ding, Hong-Gang Cheng, Xin Hong* and Qianghui Zhou*. Angew. Chem. Int. Ed. 2021, 60, 12824-12828. DOI: 10.1002/anie.202103428(VIP)
12. A Concise Total Synthesis of (–)-Berkelic Acid. Hong-Gang Cheng†, Zhenjie Yang†, Ruiming Chen, Liming Cao, Wen-Yan Tong, Qiang Wei, Qingqing Wang, Chenggui Wu, Shuanglin Qu* and Qianghui Zhou*. Angew. Chem. Int. Ed. 2021, 60, 5141-5146.
11. Turning constraint into opportunity: development of a four-component Catellani reaction. Hong-Gang Cheng*, Qianghui Zhou*. Science Bulletin. 2020, 65, 1961–1963.
10. Construction of axial chirality via palladium/chiral norbornene cooperative catalysis. Ze-Shui Liu, Yu Hua†, Qianwen Gao†, Yuanyuan Ma, Hua Tang, Yong Shang, Hong-Gang Cheng , Qianghui Zhou*. Nat. Catal . 2020, 3, 727-733.
9. Modular Dual-Tasked C-H Methylation via the Catellani Strategy. Qianwen Gao, Yong Shang, Fuzhen Song, Jinxiang Ye, Ze-Shui Liu, Lisha Li, Hong-Gang Cheng, Qianghui Zhou*. J. Am. Chem. Soc. 2019, 141, 15986-15993.
8. Redox-Neutral Ortho-C‒H Amination of Pinacol Arylborates via Palladium(II)/Norbornene Catalysis for Anilines Synthesis. Shuqing Chen†, Peng Wang†, Hong-Gang Cheng, Chihui Yang and Qianghui Zhou*. Chem. Sci. 2019, 10, 8384-8389.
7. A Biocatalytic Hydroxylation Enabled Unified Approach to C19-H hydroxylated Steroids. Junlin Wang§, Yanan Zhang§, Huanhuan Liu, Yong Shang, Linjun Zhou, Penglin Wei, Wen-Bing Yin, Zixin Deng, Xudong Qu*, Qianghui Zhou*. Nature Commun. 2019, 10, 3378 .
6. The Pd(II)‐Initiated Catellani‐type Reactions. Hong-Gang Cheng, Shuqing Chen, Ruiming Chen, and Qianghui Zhou*, Angew. Chem. Int. Ed. 2019, 58, 5832–5844.
5. Bridgehead-Modified NBEs: A Solution to ortho-Constraint in Catellani-type Reactions. Hong-Gang Cheng and Qianghui Zhou*, Chem , 2018, 4, 1775–1777. (Preview)
4. Modular One‐Step Three‐Component Synthesis of Tetrahydroisoquinolines via a Catellani Strategy. Guangyin Qian, Miao Bai, Shijun Gao, Han Chen, Siwei Zhou, Hong-Gang Cheng*, Wei Yan and Qianghui Zhou*. Angew. Chem. Int. Ed. 2018, 57, 10980 –10984.
3. The Discovery of A Pd(II)-Initiated Borono-Catellani Reaction. Shuqing Chen†, Ze-Shui Liu†, Tao Yang, Yu Hua, Zhiyu Zhou, Hong-Gang Cheng and Qianghui Zhou*. Angew. Chem. Int. Ed. 2018, 57, 7161 –7165.
2. A Palladium/Norbornene Cooperative Catalysis to Access Tetrahdronaphthalenes and Indanes with a Quaternary Center. Zeshui Liu‡, Guangyin Qian‡, Qianwen Gao, Peng Wang, Hong-Gang Cheng, Qiang Wei, Qi Liu, and Qianghui Zhou*. ACS Catal, 2018, 8, 4783–4788.
1. Epoxides as Alkylating Reagents for the Catellani Reaction. Hong-Gang Cheng, Chenggui Wu, Han Chen†, Ruiming Chen†, Guangyin Qian, Zhi Geng, Qiang Wei,Yuanyuan Xia, Jingyang Zhang, Yuming Zhang and Qianghui Zhou* . Angew. Chem. Int. Ed, 2018, 57, 3444-3448. (selected as cover)
专利：
- D. Ma, S. Zhu, S. Yu, Y. Wang, Q. Zhou, “Intermediate Compounds of Tamiflu, Methods of Preparation and Uses Thereof”, WO/2011/076086.
- L. Sierra, J. Felding, Q. Zhou, H. Renata, P. S. Baran, “C-19 Hydroxy pregnenes”, US 2016/0009751A1.
周强辉、吴承贵、程鸿刚，“一种合成2, 3-二氢苯并呋喃类化合物的方法”，专利号：ZL 201810299042.8.
周强辉、钱光印、白淼，“一种1,2,3,4-四氢异喹啉衍生物的制备方法”，专利号：ZL 201810659587.5.
周强辉、翟旭东、王军林、张亚楠，“19羟基克托多松衍生物及19-羟基雄烯二酮的制备方法”，专利号：ZL 201910517841.2.
周强辉、高倩文，“一种芳烃甲基化的制备方法” 专利号：ZL 201910695981.9.
瞿旭东，周强辉，张亚楠，王军林，“一种用于系列甾类化合物19位羟化的生物转化方法”，专利号：ZL 201910152033.0
周强辉、刘泽水、钱光印，“一种具有苄位季碳中心的苯并环衍生物的制备方法”，专利号：ZL 2018102990220.
周强辉、高仕君、钱光印，“雷美替胺的合成方法”，专利号：ZL 201910759938.4.
周强辉、刘泽水 ：“一种轴手性联芳基化合物及手性芴醇化合物的制备方法”，专利号：ZL 202010617082. X
周强辉、刘泽水：“一种轴手性膦-烯配体及其制备方法与应用”，专利号：ZL 202010618500. 7
周强辉、尚勇、吴承贵，“”一种制备尿嘧啶和胸腺嘧啶衍生物的方法”，专利号：ZL 202010807097.2.
周强辉、陈树清、王鹏，“一种芳香胺类化合物及EphB4激酶抑制剂及其衍生物的制备方法”，专利号：ZL 201910610239.3.
周强辉、尚勇、吴承贵，“一种高效合成多取代2-吡啶酮类化合物的方法”，申请号：202010807122.7.
周强辉、花昱、刘泽水：“一种基于动力学拆分策略合成手性芳基叔醇和苯并吡喃类化合物的方法”，申请号：2021103260547
周强辉、刘泽水：“一种基于手性转移策略合成 C–N轴手性菲啶酮类化合物的方法”，申请号：2021103275909
周强辉、高倩文、叶金祥：“1,2-双轴手性联芳基化合物的制备方法”，申请号：202110482565.8
周强辉、马园园：“黄酮、异黄酮类化合物的制备方法及其应用”，申请号：202111095970.0
周强辉、庄林、杨涛：“一种合成硝胺类化合物的方法”，申请号：202111482848.9
周强辉、庄林、杨涛： “一种合成硝基（杂）芳烃的方法”，申请号：202111482847.4
书本编写：
1. Hong-Gang Cheng,* Qianghui Zhou.* “Directing Group Assisted Meta C-H Functionalization of Arenes Aided by Norbornene as Transient Mediator”, in “Remote C-H Bond Functionalizations: Methods and Strategies in Organic Synthesis”, Eds: Maiti, D.; Guin, S.Wiley-VCH, 2021.
2. Ze-Shui Liu; Hong-Gang Cheng,* Qianghui Zhou.* “Epoxides as dual-functionalized alkylating reagents for the assembly of oxygen-containing heterocycles”, in “Targets in Heterocyclic Systems”, Eds: Attanasi, O. A.; Merino, P.; Spinelli, D. Italian Society of Chemistry, 2021.