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成果及论文

主要学术成绩

5年在Nature ChemistryNature communicationAdvanced Functional MaterialsComposites Part B-EngineeringChemical Engineering JournalACS Applied Materials & InterfacesAdvanced Healthcare MaterialsActa BiomaterialiaScience China Materials等国际著名期刊上发表论文50余篇。授权美国专利1项,申请PCT专利1项,申请中国发明专利30余项,授权10余项。主持企业横向课题多项,多项专利实现医学转化。

基金项目

1、 国家自然科学基金面上项目:仿生ECM聚谷氨酸/透明质酸水凝胶的可控梯度层状构筑及软骨修复研究(31771049),主持,2018.01-2021.12

2、江苏省重点研发计划项目:3D打印构建聚氨基酸仿生组织工程皮肤(BE2018731),主持,2018.07-2021.06

3、材料化学工程国家重点实验室自主课题:仿生设计的多重梯度水凝胶的可控构筑及介导BMSCs成软骨分化研究(ZK201806),主持,2018.07-2021.06

4江苏省重点研发计划项目:3D打印防粘连PCL/凝胶抗菌复合补片及促腹壁修复研究(BE2023810),主持,2023.09-2026.06.

代表性论文

[1].    Bo Chi1, et al. Designing cooperatively folded abiotic uni- and multimolecular helix bundles. Nature Chemistry, 2018,10,51-56.

[2].    Bo Chi*, et al. A click chemistry-mediated all-peptide cell printing hydrogel platform for diabetic wound healing[J]. Nature Communications, 2023, 14(1): 7856.

[3].    Bo Chi*, et al. A Biodegradable Supramolecular Adhesive with Robust Instant Wet Adhesion for Urgent Hemostasis and Wound Repair[J]. Advanced Functional Materials, 2024: 2401529.

[4].    Bo Chi*, et al. A biomimetic mussel-inspired ɛ-Poly-L-lysine hydrogel with robust tissue-anchor and anti-infection capacity. Advanced Functional Materials., 2017, 27: 1604894.

[5].    Bo Chi*, et al. Engineering the dynamics of biophysical cues in supramolecular hydrogels to facile control stem cell chondrogenesis for cartilage regeneration. Composites Part B: Engineering, 2022: 110429.

[6].    Bo Chi*, et al. Photo-driven dynamic hydrogel modulates bone marrow mesenchymal stem cells behavior for enhanced cartilage regeneration[J]. Chemical Engineering Journal, 2024: 149689.

[7].    Bo Chi*, et al. 3D printed heart valve mediated nitric oxide sustained release reduced potential for calcification and inflammatory capacity[J]. Chemical Engineering Journal, 2023, 469: 143892.

[8].    Bo Chi*, et al. S-nitrosated keratin composite mats with NO release capacity for wound healing . Chemical engineering journal, 2020, 400: 125964.

[9].    Bo Chi*, et al. Mussel-inspired dual-cross-linking hyaluronic acid/ε-polylysine hydrogel with self-healing and antibacterial properties for wound healing. ACS applied materials & interfaces, 2020, 12(25): 27876-27888.

[10]. Bo Chi*, et al. Bionic Poly(γ-Glutamic Acid) Electrospun Fibrous Scaffolds for Preventing Hypertrophic Scars. Advanced Healthcare Materials., 2019: 1900123.

[11]. Bo Chi* et al. Nitric oxide-releasing polyurethane/S-nitrosated keratin mats for accelerating wound healing. Regenerative Biomaterials, 2022, 9.

[12]. Bo Chi* et al. Bioinspired dual dynamic network hydrogels promote cartilage regeneration through regulating BMSC chondrogenic differentiation. Materials Today Chemistry, 2022, 23: 100648.

[13]. Bo Chi*, et al. Bio-inspired hydrogel-based bandage with robust adhesive and antibacterial abilities for skin closure. Science China Materials, 2022, 65(1): 246-254.

[14]. Bo Chi*, et al. Injectable adaptive self-healing hyaluronic acid/poly (γ-glutamic acid) hydrogel for cutaneous wound healing. Acta Biomaterialia, 2021, 127: 102-115. 



专利

[1].    Bo Chi, et al. ε-Polylysine hydrogel and its preparation method and application. 美国专利. 授权:WO 2015096170

[2].    Hydrogel based on γ-polyglutamic acid and ε-polylysine crosslinked polymer, and preparation method therefor. PCT专利. 公开:WO 2015085633

[3].    迟波 等,一种明胶偶联的可注射电传导复合水凝胶的制备方法及应用. 中国发明专利. 授权:CN113956509B

[4].    迟波 等,透明质酸/ε-聚赖氨酸抗菌水凝胶及其制备方法和应用. 中国发明专利. 授权:CN112190763B

[5].    迟波 等,一种光交联的γ-聚谷氨酸水凝胶及其制备方法和应用. 中国发明专利. 授权:CN111253592B

[6].    迟波 等,一种原位交联的γ-聚谷氨酸水凝胶及其制备方法和应用. 中国发明专利. 授权:CN110790951B

[7].    迟波 等,一种聚谷氨酸耐胃酸止血粘合剂. 中国发明专利. 授权:CN114344553B

[8].    迟波 等,一种防护眼镜防雾剂及其使用方法. 中国发明专利. 授权:CN111909658B

[9].    迟波 等,丙烯酸/ε-聚赖氨酸黏附性抗菌水凝胶的制备方法及其应用. 中国发明专利. 授权:CN112876694B

[10]. 迟波 等,一种聚赖氨酸抗菌组织粘合剂及应用. 中国发明专利. 授权:CN114917400B

[11]. 迟波 等,一种生物基自修复水凝胶及其制备方法和应用. 中国发明专利. 授权:CN112341640B

[12]. 迟波 等,一种仿生抗菌高粘附的双网络水凝胶及其制备方法和应用. 中国发明专利. 授权:CN111303452B

[13]. 迟波 等,一种β-环糊精修饰的CdTe量子点探针在检测农药毒死蜱中的应用. 中国发明专利. 授权:CN109946270B

[14]. 迟波 等,一种β-环糊精修饰的CdTe量子点及其制备方法. 中国发明专利. 授权:CN109943337B