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于骏(院外导师) 南通大学高层次引进人才 校聘教授 独立PI 硕士研究生导师    

个人简介:

于骏,南通大学高层次引进人才,校聘教授,独立PI,硕士研究生导师,主要从事生殖医学相关的临床和基础研究。

现为多家国家级/省级学术团体委员/青年委员主持/参与国家级及省市级项目数项,已发表SCI论文30余篇代表作发表于Nature CommunicationsRedox BiologyHuman Molecular GeneticsDevelopmentFASEB JournalCell ProliferationCell Death Disease等杂志

目前担任GeneJournal of Hazardous MaterialsMicrobiomeCell Death DiscoveryJournal of Genetics and GenomicsCell Cycle等多家SCI杂志审稿人。

 

联系电话:13921596925

邮箱:yujun9117@126.com


教育经历:

12011/09–2016/07,南京医科大学,生殖医学国家重点实验室,人体解剖与组织胚胎学专业,博士,导师:沙家豪、周作民 教授

22006/09–2011/07,南京医科大学,第一临床医学院,临床医学专业,学士


科研与学术工作经历:

12020/09-至今,南通大学,医学院,生殖医学研究院,校聘教授、硕士生导师、独立PI

22016/08-2020/08,江苏大学,附属医院,妇产科,副研究员、医师、硕士生导师


学术任职和人才计划:

1、中国妇幼保健协会妇科智能(AI)医学专业委员会青年委员

2、中国中药协会女性生殖健康药物研究专业委员会青年委员

3、江苏省免疫学会生殖免疫专业委员会委员

4、南通市医学会生殖医学分会委员

5、中国初级卫生保健基金会关爱男性健康公益基金苏中男科专家委员会常务委员

6、镇江市“169工程科技骨干

7江苏大学青年英才培育人选


主持或参加科研项目:

1、江苏省自然科学基金面上项目,BK20221376, 2022/07-2025/06, 10万,在研,主持。

2、南通市基础科学研究计划(青年科技人才创新专项),JC120220062022/07-2024/06,3万,主持。

3、国家自然科学基金青年项目,317012982018/01-2020/1223万,已结题,主持。

4、江苏省自然科学基金青年项目,BK201705622017/07-2020/0620万,已结题,主持。

5、镇江市重点研发计划(社会发展),SH20160282016/11-2018/105万,已结题,主持。

6、南京医科大学生殖医学国家重点实验室开放基金,SKLRM-KA201603, 2016/11-2018/1010万元,已结题,主持。

7、国家自然科学基金委员会,青年项目,818035052019/01-2021/1221万元,在研,参与。

8、镇江市重点研发计划(社会发展),SH20170132017/11-2019/123万元,已结题,参与。


已发表SCI论文34篇:

中科院一区Top期刊论文或IF>10分论文(6篇)(第一作者/通讯作者)

1Jun Yu (#, *), Zhiran Li (#), Yangbo Fu (#), Feiteng Sun (#), Xia Chen, Qiuru Huang, Lei He, Hao Yu, Li Ji, Xinmeng Cheng, Yi Shi, Cong Shen, Bo Zheng (*), Fei Sun (*). Single-cell RNA-sequencing reveals the transcriptional landscape of ND-42 mediated spermatid elongation via mitochondrial derivative maintenance in Drosophila testes. Redox Biol. 2023 Mar 15;62:102671.(第一作者、通讯作者;IF:10.787;中科院一区Top期刊)

2Jun Yu (#, *), Qianwen Zheng (#), Zhiran Li (#), Yunhao Wu (#), Yangbo Fu, Xiaolong Wu, Dengfeng Lin, Cong Shen, Bo Zheng(*), Fei Sun(*). CG6015 controls spermatogonia transit-amplifying divisions by epidermal growth factor receptor signaling in Drosophila testes. Cell Death Dis. 2021 May 14;12(5):491. (第一作者、通讯作者;IF: 9.685;中科院一区Top期刊)

3Min Wang, Xia Chen, Yibo Wu, Qianwen Zheng, Wanyin Chen, Yidan Yan, Xiaojin Luan, Cong Shen, Jie Fang(*), Bo Zheng(*), Jun Yu (*). RpS13 controls the homeostasis of germline stem cell niche through Rho1-mediated signals in the Drosophila testis. Cell Prolif. 2020 Sep 8; e12899. (通讯作者;IF: 8.755;中科院一区Top期刊)

4Jun Yu (#), Yidan Yan(#), Xiaojin Luan(#), Chen Qiao(#), Yuanyuan Liu(#), Dan Zhao, Bing Xie, Qianwen Zheng, Min Wang, Wanyin Chen, Cong Shen, Zeyu He, Xing Hu, Xiaoyan Huang, Hong Li, Qixiang Shao, Xia Chen(*), Bo Zheng(*) and Jie Fang(*). Srlp is crucial for the self-renewal and differentiation of germline stem cells via RpL6 signals in Drosophila testes. Cell Death Dis. 2019 Apr 1; 10 (4): 294. (第一作者;IF: 9.685;中科院一区Top期刊)

5Zhibin Hu(#)(*)Zheng Li(#)Jun Yu(#)Chao Tong(#)Yuan Lin(#)Xuejiang Guo(#)Feng LuJing DongYankai XiaYang WenHao WuHonggang LiYong ZhuPing PingXiangfeng ChenJuncheng DaiYue JiangShandong PanPeng XuKailing LuoQiang DuBing YaoMing LiangYaoting GuiNing WengHui LuZhuqing WangFengbin ZhangXiaobin ZhuXiaoyu YangZhou ZhangHan ZhaoChenliang XiongHongxia MaGuangfu JinFeng ChenJianfeng XuXinru WangZuomin ZhouZi-Jiang Chen(*)Jiayin Liu(*)Hongbing ShenJiahao Sha(*). Association analysis identifies new risk loci for non-obstructive azoospermia in Chinese men. Nat Commun. 2014, 5:3857. (共同第一作者;IF: 17.694;中科院一区Top期刊)

6Jun Yu (#), Cong Shen (#), Meng Lin (#), Xia Chen (#), Xiuliang Dai, Zhiran Li, Yunhao Wu, Yangbo Fu, Jinxing Lv, Xiaoyan Huang (*), Bo Zheng (*), Fei Sun (*). BMI1 promotes spermatogonial stem cell maintenance by epigenetically repressing Wnt10b/β-catenin signaling. Int J Biol Sci. 2022; 18(7): 2807-2820.(第一作者;IF: 10.75;中科院二区)

 

中科院二区Top期刊论文(4篇)(第一作者/通讯作者)

7Jun Yu (#, *), Jinfu Xu (#), Hong Li (#), Pengfei Wu, Shiyao Zhu, Xiaoyan Huang, Cong Shen, Bo Zheng (*), Wenqing Li (*). Gold nanoparticles retrogradely penetrate through testicular barriers via Sertoli-cells mediated endocytosis/exocytosis and induce immune response in mouse. Ecotox Environ Safe. 2023 (Accept)(第一作者、通讯作者;IF: 7.129;中科院二区Top期刊)

8Jun Yu(#)(*), Xiaojin Luan(#), Yidan Yan(#), Chen Qiao(#), Yuanyuan Liu(#), Dan Zhao, Bing Xie, Qianwen Zheng, Min Wang, Wanyin Chen, Cong Shen, Zeyu He, Xing Hu, Xiaoyan Huang, Hong Li, Binghai Chen, Bo Zheng(#), Xia Chen(#), and Jie Fang(*). Small ribonucleoprotein particle protein SmD3 governs the homeostasis of germline stem cells and the crosstalk between the spliceosome and ribosome signals in Drosophila. FASEB J. 2019 Jul; 33 (7): 8125-8137. (第一作者、通讯作者;IF: 5.834;中科院二区Top期刊)

9Jun Yu(#)Xiang Lan(#)Xia Chen(#)Chao YuYiwen XuYujuan LiuLingna XuHeng-Yu FanChao Tong(*). Protein synthesis and degradation are essential to regulate germline stem cell homeostasis in Drosophila testes. Development. 2016, 143 (16): 2930-2945. (第一作者;IF: 6.862;中科院二区Top期刊)

10Jun Yu(#)Hao Wu(#)Yang Wen(#)Yujuan Liu(#)Tao ZhouBixian NiYuan LinJing DongZuomin ZhouZhibin Hu(*)Xuejiang Guo(*)Jiahao Sha(*)Chao Tong(*). Identification of seven genes essential for male fertility through a genome-wide association study of non-obstructive azoospermia and RNA interference-mediated large-scale functional screening in Drosophila. Hum Mol Genet. 2015, 24 (5):1493-1503.(第一作者;IF: 5.121;中科院二区Top期刊)

 

中科院二区论文(5篇)(第一作者/通讯作者)

11Jun Yu (#), Yangbo Fu (#), Zhiran Li (#), Qiuru Huang (#), Juan Tang, Chi Sun, Peiyao Zhou, Lei He, Feiteng Sun, Xinmeng Cheng, Li Ji, Hao Yu, Yi Shi, Zhifeng Gu (*), Fei Sun (*), Xinyuan Zhao (*). Single-cell RNA sequencing reveals cell landscape following antimony exposure during spermatogenesis in Drosophila testes. Cell Death Discov. 2023 Mar 9;9(1):86. (第一作者;IF: 7.109;中科院二区)

12Zhiran Li (#), Yunhao Wu (#), Yangbo Fu (#), Xia Chen (#), Xi Zhao, Xiaolong Wu, Yajuan Lu, Hui He, Cong Shen, Bo Zheng (*), Jun Yu (*), Fei Sun (*). Cyst stem cell lineage eIF5 non-autonomously prevents testicular germ cell tumor formation via eIF1A/eIF2γ mediated pre-initiation complex. Stem Cell Res Ther. 2022 Jul 26;13(1):351. 通讯作者;IF: 8.079;中科院二区

13Jun Yu (#), Yibo Wu (#), Hong Li (#), Hui Zhou, Cong Shen, Tingting Gao, Meng Lin, Xiuliang Dai, Jian Ou, Meiling Liu, Xiaoyan Huang (*), Bo Zheng (*), Fei Sun (*). BMI1 Drives Steroidogenesis Through Epigenetically Repressing the p38 MAPK Pathway. Front Cell Dev Biol. 2021 Apr 13;9:665089. (第一作者;IF: 6.081;中科院二区)

14Qianwen Zheng, Xia Chen, Chen Qiao, Min Wang, Wanyin Chen, Xiaojin Luan, Yidan Yan, Cong Shen, Jie Fang, Xing Hu, Bo Zheng (*), Yibo Wu (*), Jun Yu (*). Somatic CG6015 mediates cyst stem cell maintenance and germline stem cell differentiation via EGFR signaling in Drosophila testes. Cell Death Discov. 2021 Apr 6;7(1):68. (通讯作者;IF: 7.109;中科院二区)

15Wanyin Chen, Xiaojin Luan, Yidan Yan, Min Wang, Qianwen Zheng, Xia Chen(*), Jun Yu(*), Jie Fang(*). CG8005 Mediates Transit-Amplifying Spermatogonial Divisions via Oxidative Stress in Drosophila Testes. Oxid Med Cell Longev. 2020 Oct 27; 2020: 2846727.(通讯作者;IF: 7.31;中科院二区)

 

其他SCI论文(11篇)(第一作者/通讯作者)

16Xia Chen (#), Qianwen Zheng (#), Li Ji (#), Yanyan Zhuang (#), Hao Yu, Xinmeng Cheng, Yun Han, Jinxing Lv, Bo Zheng (*), Yanli Zheng (*), Jun Yu (*). Quantitative proteomics and functional analysis identified novel targets for missed abortion. Exp Cell Res. 2022 Aug 15;417(2):113216. (通讯作者;IF: 4.145;中科院三区)

17Meng Lin (#), Jinxing Lv (#), Dan Zhao (#), Siyu Liu, Jinfu Xu, Yangyang Wu, Fuxin Wang, Jun Zhang, Bo Zheng, Cong Shen (*), Xie Guan (*), Jun Yu (*), Xiaoyan Huang (*). MRNIP is essential for meiotic progression and spermatogenesis in mice. Biochem Biophys Res Commun. 2021 Apr 23;550:127-133. (通讯作者;IF: 3.322;中科院三区)

18Tingting Gao(#), Meng Lin(#), Binbin Shao(#), Qiao Zhou(#), Yufeng Wang(#), Xia Chen, Dan Zhao, Xiuliang Dai, Cong Shen, Hongbo Cheng, Shenmin Yang, Hong Li, Bo Zheng(*), Xingming Zhong(*), Jun Yu (*), Li Chen(*), Xiaoyan Huang(*). BMI1 promotes steroidogenesis through maintaining redox homeostasis in mouse MLTC-1 and primary Leydig cells. Cell Cycle. 2020 Aug; 19 (15):1884-1898.(通讯作者;IF: 5.173;中科院三区

19Dan Zhao(#), Cong Shen(#) (*), Tingting Gao(#), Hong Li(#), Yueshuai Guo(#), Feng Li, Chenchen Liu, Yuanyuan Liu, Xia Chen, Xi Zhang, Yangyang Wu, Yi Yu, Meng Lin, Yan Yuan, Xiaofang Chen, Xiaoyan Huang, Shenmin Yang(*), Jun Yu (*), Jun Zhang(*), Bo Zheng(*). Myotubularin related protein 7 is essential for the spermatogonial stem cell homeostasis via PI3K/AKT signaling. Cell Cycle. 2019 Oct;18 (20): 2800-2813. (通讯作者;IF: 5.173;中科院三区

20Cong Shen(#), Jun Yu (#), Xi Zhang, ChenChen Liu, YueShuai Guo, JiaWei Zhu, Ke Zhang, Yi Yu, TingTing Gao, ShenMin Yang, Hong Li, Bo Zheng(*), XiaoYan Huang(*). Strawberry Notch 1 (SBNO1) promotes proliferation of spermatogonial stem cells via the noncanonical Wnt pathway in mice. Asian J Androl. 2019;21(4):345-350. (共同第一作者;IF:3.054中科院三区

21Xia Chen(#), Xiaojin Luan(#), Qianwen Zheng(#), Chen Qiao(#), Wanyin Chen, Min Wang, Yidan Yan, Bing Xie, Cong Shen, Zeyu He, Jun Zhang, Mingxi Liu, Xing Hu, Hong Li, Bo Zheng(*), Jie Fang(*) and Jun Yu (*). Precursor RNA processing 3 is required for male fertility, and germline stem cell self-renewal and differentiation via regulating spliceosome function in Drosophila testes. Sci Rep. 2019 Jul 10; 9 (1): 9988.(通讯作者,IF: 4.996中科院三区

22Jie Fang(#)(*), Xueke Guo(#), Bo Zheng(#), Wei Han(#), Xia Chen(#), Jiawei Zhu(#), Bing Xie, Jiajia Liu, Xiaojin Luan, Yidan Yan, Zeyu He, Hong Li, Chen Qiao, Jun Yu (*). Correlation between NM23 protein overexpression and prognostic value and clinicopathologic features of ovarian cancer: a meta-analysis. Arch Gynecol Obstet. 2018, 297 (2): 449-458. (通讯作者;IF: 2.493;中科院三区)

23Cong Shen(#), Ke Zhang(#), Jun Yu (#), Yueshuai Guo(#), Tingting Gao, Yuanyuan Liu, Xi Zhang, Xia Chen, Yi Yu, Hongbo Cheng, Aiyan Zheng, Hong Li(*), Xiaoyan Huang(*), Xufeng Ding(*), Bo Zheng(*). Stromal interaction molecule 1 is required for neonatal testicular development in mice. Biochem Biophys Res Commun. 2018 Oct 12; 504 (4): 909-915.(共同第一作者;IF: 3.322;中科院三区)

24Bo Zheng(#)(*), Jun Yu (#), Yueshuai Guo(#), Tingting Gao, Cong Shen, Xi Zhang, Hong Li(*), Xiaoyan Huang(*). Cellular nucleic acid-binding protein is vital to testis development and spermatogenesis in mice. Reproduction. 2018 Jul;156 (1): 59-69. (共同第一作者;IF:3.923中科院三区

25Cong Shen(#), Jinfu Xu(#), Qiao Zhou(#), Meng Lin, Jinxing Lv, Xi Zhang, Yangyang Wu, Xia Chen, Jun Yu (*), Xiaoyan Huang(*), Bo Zheng(*). E3 ubiquitin ligase ASB17 is required for spermiation in mice. Transl Androl Urol. 2021 Dec;10(12):4320-4332. (通讯作者;IF: 2.479;中科院四区)

26Xifeng Yin(#), Jun Yu(#), Yang Zhou, Chengyue Wang, Zhimin Jiao, Zhounan Qian, Hao Sun, Binghai Chen(*). Identification of CDK2 as a novel target in treatment of prostate cancer. Future Oncol. 2018, 14 (8): 709-718. (共同第一作者;IF:3.674中科院四区

 

其他SCI论文(8篇)(共同作者)

27Hao Wu(#)Liwei Sun(#)Yang Wen(#)Yujuan LiuJun YuFeiyu MaoYa WangChao TongXuejiang GuoZhibin HuJiahao ShaMingxi Liu(*)Laixin Xia(*). Major spliceosome defects cause male infertility and are associated with non-obstructive azoospermia in humans. Proc Natl Acad Sci USA. 2016, 113 (15): 4134-4139. (共同作者;IF:12.779;中科院一区Top期刊)

28Meina Yan, Xinxin Yang, Rong Shen, Chengjiang Wu, Hui Wang, Qing Ye, Peifang Yang, Lubin Zhang, Miao Chen, Bing Wan, Qinqin Zhang, Sheng Xia, Xiaodong Lu, Genbao Shao, Xiaoming Zhou, Jun Yu and Qixiang Shao(*). miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer. Cell Death Dis. 2018 Nov 8; 9 (11): 1123. (共同作者;IF: 9.685;中科院一区Top期刊

29Bixian Ni(#)Yuan Lin(#)Liangdan Sun(#)Meng Zhu(#)Zheng LiHui WangJun YuXuejiang GuoXianbo ZuoJing DongYankai XiaYang WenHao WuHonggang LiYong ZhuPing PingXiangfeng ChenJuncheng DaiYue JiangPeng XuQiang DuBing YaoNing WengHui LuZhuqing WangXiaobin ZhuXiaoyu YangChenliang XiongHongxia MaGuangfu JinJianfeng XuXinru WangZuomin ZhouJiayin LiuXuejun ZhangDonald F. ConradZhibin Hu(*)Jiahao Sha(*). Low-frequency germline variants across 6p22.2-6p21.33 are associated with non-obstructive azoospermia in Han Chinese men. Hum Mol Genet. 2015, 24 (19): 5628-5636.(共同作者;IF: 5.121;中科院二区Top期刊)

30Ni Huang(#)Yang Wen(#)Xuejiang GuoZheng LiJuncheng DaiBixian NiJun YuYuan LinWen ZhouBing YaoYue JiangJiahao Sha(*)Donald F. Conrad(*)Zhibin Hu(*). A Screen for Genomic Disorders of Infertility Identifies MAST2 Duplications Associated with Non-Obstructive Azoospermia in Humans. Biol Reprod. 2015, 93 (3): 61. (共同作者;IF: 4.161;中科院二区)

31Min Wang(#), Juan-Juan Tang(#), Lin-Xiao Wang, Jun Yu, Li Zhang(*), Chen Qiao(*). Hydrogen sulfide enhances adult neurogenesis in a mouse model of Parkinson's disease. Neural Regen Res. 2021 Jul; 16(7): 1353-1358. (共同作者;IF: 6.058;中科院二区)

32Gaigai Wang(#), Yueshuai Guo(#), Tao Zhou(#), Xiaodan Shi(#), Jun Yu, Ye Yang, Yibo Wu, Jing Wang, Mingxi Liu, Xin Chen, Wenjiao Tu, Yan Zeng, Min Jiang, Suying Li, Pan Zhang, Quan Zhou, Bo Zheng, Chunmei Yu, Zuomin Zhou, Xuejiang Guo(*), Jiahao Sha(*). In-depth proteomic analysis of the human sperm reveals complex protein compositions. J Proteomics. 2013 Feb 21;79:114-22. (共同作者;IF:3.855;中科院二区)

33Xia Chen (#), Yanli Zheng (#), Yun Han (#), Hui He (#), Jinxing Lv, Jun Yu, Hong Li, Shunyu Hou (*), Cong Shen (*), Bo Zheng (*). SAT2 regulates Sertoli cell–germline interactions via STIM1‐mediated ROS/WNT/β‐catenin signaling pathway. Cell Biol Int. 2022 Oct;46(10):1704-1713.(共同作者;IF: 4.473;中科院三区)

34Yangyang Wu (#), Ting Wang (#), Zigao Zhao, Siyu Liu, Cong Shen, Hong Li, Mingxi Liu, Bo Zheng (*), Jun Yu, Xiaoyan Huang (*). Retinoic Acid Induced Protein 14 (Rai14) is dispensable for mouse spermatogenesis. PeerJ. 2021; 9: e10847. (共同作者;IF: 3.061;中科院三区)

 

国家发明专利:

1于骏;陈霞;COX6C蛋白在制备早期妊娠丢失诊断的试剂盒中的应用, 2022-08-02,中国, ZL202111159814.6

2)郑波;于骏;李红;吴亦波;沈聪;陈霞;杨慎敏;提高囊胚率的小鼠精子体外培养试剂盒及其使用方法,2022-02-11,中国,ZL201811056268.1

 

大会报告:

1于骏;翻译起始因子在睾丸干细胞微环境中的研究进展,2022年江苏省免疫学会生殖免疫专业委员会生殖免疫研究进展学习班,江苏南京,2022-11-122022-11-13

2于骏CG6015 controls spermatogonia transit-amplifying divisions by Epidermal Growth Factor Receptor signaling in Drosophila testes2021国际暨中国第六届果蝇生物学大会,广东广州,2021-11-102021-11-12