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成果及论文

代表性科研论文:First author/Co-first author (#) 


Zhaofeng Li#, Meng Su#, Xinshu Xie#, Pan Wang, Honghao Bi, Ermin Li, Kehan Ren, Lili Dong, Zhiyi Lv, Xuezhen Ma, Yijie Liu, Baobing Zhao, Yuanliang Peng, Jing Liu, Lu Liu, Jing Yang, Peng Ji*, Yang Mei*. mDia formins form hetero-oligomers and cooperatively maintain murine hematopoiesis. PLOS Genetics. 2023, 19, e1011084 (Co-corresponding author) (IF= 6.02)   (https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011084)


Yang Mei#, Kehan Ren#, Yijie Liu, Annabel Ma, Zongjun Xia, Xu Han, Ermin Li, Hamza Tariq, Haiyan Bao, Xinshu Xie, Cheng Zou, Dingxiao Zhang, Zhaofeng Li, Lili Dong, Amit Verma, Xinyan Lu, Yasmin Abaza, Jessica K Altman, Madina Sukhanova, Jing Yang, Peng Ji. Bone marrow–confined IL-6 signaling mediates the progression of myelodysplastic syndromes to acute myeloid leukemia. J Clin Invest. 2022. 132. (Co-corresponding author) (IF= 19.456, Cover Story (https://www.jci.org/articles/view/152673)


Yang Mei, Yijie Liu, Peng Ji. Understanding terminal erythropoiesis: An update on chromatin condensation, enucleation, and reticulocyte maturation. Blood Reviews. 2021. 46:100740. (Co-corresponding author) (IF=10.626) (https://pubmed.ncbi.nlm.nih.gov/32798012/)


Yijie Liu, Yang Mei, Xu Han, Farida V Korobova, Miguel A Prado, Jing Yang, Zhangli Peng, Joao Paulo, Steven Gygi, Daniel Finley, Peng Ji. Membrane skeleton modulates erythroid proteome remodeling and organelle clearance. Blood. 2020. 137(3):398-409. (IF= 25.476, Cover Story) (https://pubmed.ncbi.nlm.nih.gov/33036023/)


Yang Mei#, Samuel E. Weinberg#, Lihui Zhao, Adam Frink, Chao Qi, Amir Behdad, Peng Ji, Risk stratification of hospitalized COVID-19 patients through comparative studies of laboratory results with influenza. EClinicalMedicine. 2020, 100475. (IF= 17.033) (https://pubmed.ncbi.nlm.nih.gov/33089115/)

Comment in: Differentiating diagnosis of COVID-19 or influenza in patients based on laboratory data during flu season. Shuwen Liu, Chungen Pan. EClinicalMedicine. 2020. 26, 100475.) 


Yang Mei#, Xu Han, Yijie Liu, Jing Yang, Ronen Sumagin, and Peng Ji#. Diaphanous-related formin mDia2 regulates beta2 integrins to control hematopoietic stem and progenitor cell engraftment. Nat Commun. 2020 Jun 23;11(1):3172. (Co-corresponding author) (IF= 17.694)(https://pubmed.ncbi.nlm.nih.gov/32576838/)


Yang Mei, Baobing Zhao, Ashley A Basiorka, Jing Yang, Lan Cao, JingxinZhang, Alan List, and Peng Ji. Age-related inflammatory bone marrow microenvironment induces ineffective erythropoiesis mimicking del(5q) MDS. Leukemia. 2018,32(4):1023-1033. (IF= 12.883) (https://pubmed.ncbi.nlm.nih.gov/29263441/)


Baobing Zhao, Yang Mei, Lan Cao, Jingxin Zhang, Ronen Sumagin, Jing Yang, Juehua Gao, Matthew J. Schipma, Yanfeng Wang, Chelsea Thorsheim, Liang Zhao, Timothy Stalker, Brady Stein, Qiang Jeremy Wen, John D. Crispino, Charles S. Abrams, and Peng Ji. Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms. J Clin Invest. 2018, 128(1):125-140. (IF= 19.456) (https://pubmed.ncbi.nlm.nih.gov/29202466/)


Yang Mei, Gong Feng, Nina Rahimi, Baobing Zhao, Jingxin Zhang, Lan Cao, Jing Yang, Juehua Gao, Yihua Chen, Ronen Sumagin, William A. Muller, Ling Zhang and Peng Ji. Loss of mDia1 causes neutropenia via attenuated CD11b endocytosis and increased neutrophil adhesion to the endothelium. Blood Advances.2017,1:1650-1656. (IF= 7.637) (https://pubmed.ncbi.nlm.nih.gov/29296812/)


Xuehui Li#, Yang Mei#, Bowen Yan#, Eric Vitriol, Suming Huang, Peng Ji, and Yi Qiu. Histone deacetylase 6 regulates cytokinesis and erythrocyte enucleation through deacetylation of formin protein mDia2. Haematologica. 2017, 102(6): 984-994. (IF= 11.047) (https://pubmed.ncbi.nlm.nih.gov/28255013/)


Yang Mei, Baobing Zhao, Jing Yang, Juehua Gao, Amittha Wickrema, Dehua Wang, Yihua Chen, Peng Ji. Ineffective Erythropoiesis Caused by Binucleated Late-Stage Erythroblasts in mDia2 Hematopoietic Specific Knockout Mice. Haematologica. 2016, 101(1): e1–e5. (IF= 11.047) (https://pubmed.ncbi.nlm.nih.gov/26471482/)


Baobing Zhao, Yang Mei, Matthew J. Schipma, Eric Wayne Roth, Reiner Bleher, Joshua Z. Rappoport, AmitthaWickrema, Jing Yang, Peng Ji, Nuclear Condensation during Mouse Erythropoiesis Requires Caspase-3-Mediated Nuclear Opening, Dev Cell. 2016, 36(5):498-510. (IF= 12.270, Cover Story(https://pubmed.ncbi.nlm.nih.gov/26954545/)

Comment in: Chromatin Condensation and Enucleation in Red Blood Cells: An Open Question. Margaret H Baron, Jeffrey Barminko. Dev Cell. 2016, 36(5):481-2.


Ganesan Keerthivasan#, Yang Mei#, Baobing Zhao, Ling Zhang, Chad E. Harris, Juehua Gao, Ashley A. Basiorka, Matthew J. Schipma, James McElherne, Jing Yang, Amit K. Verma, Andrea Pellagatti, Jacqueline Boultwood, Alan F. List, David A. Williams, and Peng Ji. Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) myelodysplastic syndromes. Blood2014, 124(5): 780-90. (IF= 25.476) (https://pubmed.ncbi.nlm.nih.gov/24891322/)

Comment in: Errant innate immune signaling in del(5q) MDS. Starczynowski DT. Blood. 2014, 31; 124(5): 669-71.


Yang Mei#, Zhanxiang Wang#, Lei Zhang#, Yiru Zhang, Xiaoyu Li, Huihui Liu, Jing Ye, and Han You.   Regulation of neuroblastoma differentiation by forkhead transcription factors FOXO1/3/4 through the receptor tyrosine kinase PDGFRA. Proc Natl AcadSci U S A. 2012, 109(13): 4898-903. (IF= 12.779) (https://pubmed.ncbi.nlm.nih.gov/22411791/)


Yang Mei#, Yiru Zhang#, Kazuo Yamamoto, Wei Xie, Tak W. Mak and Han You. FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation. Proc Natl AcadSci U S A. 2009, 106(13): 5153-8. (IF= 12.779) (https://pubmed.ncbi.nlm.nih.gov/19276113/)

Editors' Choice: Cell Survival, In the Pink1 with FOXO3a. Elizabeth MA, Sci. Signal. 2009, 2 (65), ec122.