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成果及论文

2024

[1] Fulong Ma#, Qian Jia#, Ziwei Deng#, Bingzhe Wang, Siwei Zhang, Jinhui Jiang, Guichuan Xing, Zhongliang Wang, Zijie Qiu, Zheng Zhao*, Ben Zhong Tang*, Boosting Luminescence Efficiency of NIR-II AIEgens via a Mash-Up Strategy of π-Extension and Deuteration for Dual-Model Image-Guided Surgery. ACS Nano, 2024, 18(13):9431 – 9442.

[2] Pengbo Ning*#, Fuyu Du#, Haotian Wang#, Xiaocheng Gong, Yuqiong Xia,  Xianghan Zhang, Hongzhang Deng, Ruili Zhang*Zhongliang Wang*, Genetically Engineered Macrophages as Living Cell Drug Carriers for Targeted Cancer TherapyJournal of Controlled Release, 2024, 367:697 – 707.


2023

[1] Yuqiong Xia, Keyun Wu, Chang Liu, Xuejuan Zhao, Jun Wang, Jianxia Cao, Zhaoxu Chen, Minchao Fang, Jie Yu, Cheng Zhu, Xianghan Zhang*, Zhongliang Wang*Filamentous-Actin-Mimicking Nanoplatform for Enhanced Cytosolic Protein Delivery, Advanced Science, 2023, e2305600.

[2] Qian Jia, Ruili Zhang, Haohao Yan, Yanbin Feng, Fang Sun, Zuo Yang, Chaoqiang Qiao, Xiaocheng Mou, Jie Tian and Zhongliang Wang*, An Activatable Near-Infrared Fluorescent Probe for Precise Detection of the Pulmonary Metastatic Tumors: A Traditional Molecule Having a Stunning Turn. Angewandte Chemie International Edition, 2023, e202313420.

[3] Zhiguo Fang, Chenlei Wang, Jingrun Yang, Zhizheng Song, Chunyu Xie, Yu Ji, Zhongliang Wang, Xiaohui Du, Qiang Zheng, Chunying Chen*, Zhiyuan Hu* and Yeteng Zhong*, Oxyhaemoglobin saturation NIR-IIb imaging for assessing cancer metabolism and predicting the response to immunotherapy, Nature Nanotechnology, 2023, DOI: 10.1038/s41565-023-01501-4.

[4] Xiao Xiong, Li He, Qingchao Ma, Yihan Wang, Ke Li, Zhongliang Wang, Xueli Chen, Shouping Zhu*, Yonghua Zhan*, Xu Cao*, Indocyanine green based fluorescence imaging improved by deep learning, Journal of Biophotonics, 2023, e202300066.

[5] Zhiping Rao, Yutian Xia, Qian Jia, Yutong Zhu, Lexuan Wang, Guohuan Liu, Xuelan Liu, Peng Yang, Pengbo Ning, Ruili Zhang, Xianghan Zhang, Chaoqiang Qiao*, Zhongliang Wang*, Iron-Based Metal-Organic Framework Co-Loaded with Buthionine Sulfoximine and Oxaliplatin for Enhanced Cancer Chemo-Ferrotherapy via Sustainable Glutathione Elimination, Journal of Nanobiotechnology2023, 21(1):265. 

[6] Zhuang Chen, Weijing Liu, Zuo Yang*, Yi Luo, Chaoqiang Qiao, Anna Xie, Qian Jia, Peng Yang*, Zhongliang Wang*, Ruili Zhang*, Sonodynamic-immunomodulatory nanostimulators activate pyroptosis and remodel tumor microenvironment for enhanced tumor immunotherapy, Theranostics, 2023, 13(5), 1571-1583.  


2022

[1] Chaoqiang Qiao, Zuo Yang, Xuelan Liu, Ruili Zhang, Yuqiong Xia*, Lexuan Wang, Zhuang Chen, Qian Jia, Ruhao Wang, Yang Yang*, Zhongliang Wang*, Post-Remedial Oxygen Supply: A New Perspective on Photodynamic Therapy to Suppress Tumor Metastasis, Nano Letters, 2022, 22(20), 8250–8257. 

[2] Zuo Yang, Chaoqiang Qiao, Qian Jia, Zhuang Chen, Xiaofei Wang, Xuelan Liu, Ruili Zhang*, Kanyi Pu*, Zhongliang Wang*, Redox dyshomeostasis modulation of the tumor intracellular environment through a metabolic intervention strategy for enhanced photodynamic therapy, Theranostics, 2022, 12(14), 6143-6154. 

[3] Jie Yu, Ruili Zhang, Baihang Chen‡, Xuelan Liu, Qian Jia, Xiaofei Wang, Zuo Yang, Pengbo Ning*, Zhongliang Wang*, Yang Yang*, Injectable Reactive Oxygen Species-Responsive Hydrogel Dressing with Sustained Nitric Oxide Release for Bacterial Ablation and Wound Healing, Advanced Functional Materials,  2022, 32(33), 2202857.  

[4] Zhiping Rao, Yutong Zhu, Peng Yang, Zhuang Chen, Yuqiong Xia, Chaoqiang Qiao, Weijing Liu, Hongzhang Deng, Jianxiong Li*, Pengbo Ning*, Zhongliang Wang*, Pyroptosis in inflammatory diseases and cancer, Theranostics, 2022, 12(9), 4310-4329. 

[5] Xianghan Zhang, Jingkai Gao, Yingdi Tang, Jie Yu, Si Si Liew, Chaoqiang Qiao, Guohuan Liu, Hongyu Fan, Yuqiong Xia, Jie Tian*, Kanyi Pu* and Zhongliang Wang*, Bioorthogonally activatable cyanine dye with torsion-induced disaggregation for in vivo tumor imaging, Nature Communications, 2022, 13(1), 3513. 

[6] Shaohua Qu, Qian Jia, Zheng Li, Zhongliang Wang*, and Li Shang*, Chiral NIR-II fluorescent Ag2S quantum dots with stereospecific biological interactions and tumor accumulation behaviors, Science Bulletin, 2022, 67(12), 1274-1283. 

[7] Jie Yu, Hua Xiao, Zuo Yang‡, Chaoqiang Qiao‡, Bin Zhou‡, Qian Jia, Zhongdi Wang, Xiaofei Wang, Ruili Zhang*, Yang Yang*, Zhongliang Wang*, and Jianxiong Li*, A Potent Strategy of Combinational Blow toward Enhanced Cancer Chemo-Photodynamic Therapy via Sustainable GSH Elimination, Small, 2022, 18(9), e2106100. 

[8] Hongzhang Deng, Zuo Yang, Xiaoyu Pang, Caiyan Zhao*, Jie Tian*, Zhongliang Wang*, Xiaoyuan Chen*, Self-Sufficient Copper Peroxide Loaded pKa-Tunable Nanoparticles for Lysosome-Mediated Chemodynamic Therapy, Nano Today, 2022, 42, 101337. 

[9] Chaoqiang Qiao‡, Xiaofei Wang‡, Guohuan Liu, Zuo Yang, Qian Jia, Lexuan Wang, Ruili Zhang, Yuqiong Xia*, Zhongliang Wang*, Yang Yang*, Erythrocyte Membrane Camouflaged Metal-Organic Framework Nanodrugs via Remodeling Tumor Microenvironment for Enhanced Tumor Chemotherapy, Advanced Functional Materials, 2022, 32(6), 2107791. 

[10] Qian Jia, Ruili Zhang, Yongdong Wang, Haohao Yan, Zheng Li, Yanbin Feng, Yu Ji, Zuo Yang, Yang Yang*, Kanyi Pu, Zhongliang Wang*, A Metabolic Acidity-Activatable Calcium Phosphate Probe with Signal Amplification Capabilities for Non-Invasive Fluorescence Imaging of Tumors, Science Bulletin, 2022, 67, 288-298. 


2021

[1] Qian Jia, Zheng Li, Mingli Bai, Haohao Yan, Ruili Zhang*, Yu Ji, Yanbin Feng, Zuo Yang, Zhongliang Wang*, and Jianxiong Li*, Estimating dynamic vascular perfusion based on Er-based lanthanide nanoprobes with enhanced down-conversion emission beyond 1500 nm, Theranostics, 2021, 11(20), 9859-9872. 

[2] Peng Yang, Zhuang Chen, Shaojie Liu, Chaoqiang Qiao, Yuqiong Xia*, Zhongliang Wang*, Recent progress in drug delivery and cancer theranostic built from metal-organic frameworks, Biomedical Materials,  2021, 16(4), 042011. 

[3] Xianghan Zhang, Sumei Zhao, Zhiqing Gao, Jialin Zhou, Yuqiong Xia, Jie Tian*, Changhong Shi*, Zhongliang Wang*, Liposome trade-off strategy in mitochondria-targeted NIR-cyanine: balancing blood circulation and cell retention for enhanced anti-tumor phototherapy in vivo, Nano Research2021, 14, 2432-2440. 


2020

[1] Yuqiong Xia, Pengbo Ning, Zhongliang Wang*Xiaoyuan Chen*, Calming the Cytokine Storm in Pneumonia by Biomimetic Nanoparticles, Matter, 2020, 3(1), 18-20. 

[2] Chaoqiang Qiao, Ruili Zhang, Yongdong Wang‡, Qian Jia‡, Xiaofei Wang, Zuo Yang, Tengfei Xue, Renchuan Ji, Xiufang Cui, and Zhongliang Wang*, Rabies Virus-Inspired Metal-Organic Frameworks for Targeted Imaging and Chemotherapy of Glioma, Angewandte Chemie International Edition2020, 59(39), 16982-16988. 

[3] Yuqiong Xia, Lang Rao, Huimin Yao, Zhongliang Wang*, Pengbo Ning*, Xiaoyuan Chen*, Engineering macrophages for cancer immunotherapy and drug delivery, Advanced Materials, 2020, 32(40), e2002054. 

[4] Ruili Zhang, Linlin Wang, Xiaofei Wang, Qian Jia, Zhuang Chen, Zuo Yang, Renchuan Ji, Jie Tian, and Zhongliang Wang*, Acid-Induced in Vivo Assembly of Gold Nanoparticles for Enhanced Photoacoustic Imaging-Guided Photothermal Therapy of Tumors, Advanced Healthcare Materials, 2020, 9(14), 2000394. 

[5] Wenjia Duan, Qi Yue, Ying Liu, Yunfei Zhang, Qinghua Guo, Cong Wang, Shujie Yin, Dandan Fan, Wenjing Xu, Jiexian Zhuang, Jiachao Gong, Xinwei Li, Ruimin Huang, Liang Chen, Silvio Aime, Zhongliang Wang, Jianfeng Feng, Ying Mao*, Xiao-Yong Zhang*, and Cong Li*, pH ratiometrically responsive surface enhanced resonance Raman scattering probe for tumor acidic margin delineation and image-guided surgery, Chemical Sciences, 2020, 11, 4397-4402.

[6] Na Zhao*, Yue Li, Wei Yin, Jiabao Zhuang, Qian Jia, Zhongliang Wang, Nan Li*, Controllable Coumarin-Based NIR Fluorophores: Selective Subcellular Imaging, Cell Membrane Potential Indication, and Enhanced Photodynamic Therapy, ACS Applied Materials & Interfaces2020, 12, 2, 2076-2086.

 

2019

[1] Ruili Zhang, Chaoqiang Qiao, Qian Jia, Yongdong Wang, Huimin Huang, Wanwan Chang, He Wang, Hao Zhang, Zhongliang Wang*, Highly Stable and Long-Circulating Metal-Organic Frameworks Nanoprobes for Sensitive Tumor Detection In Vivo, Advanced Healthcare Materials  2019, 8(19), 1900761. 

[2] Ruili Zhang, Zhe Wang, Zuo Yang, Linlin Wang, Zhongdi Wang, Baihang Chen, Zhongliang Wang*, Jie Tian*, RNA-silencing nanoprobes for effective activation and dynamic imaging of neural stem cells differentiation, Theranostics 2019, 9(18), 5386-5395. 

[3] Yuqiong Xia, Chunzhong Xu, Xianghan Zhang, Pengbo Ning, Zhongliang Wang*, Jie Tian*, Xiaoyuan Chen*, Liposome-based probes for molecular imaging: from basic research to the bedside, Nanoscale 2019, 11, 5822-5838. 


2018

[1] Yunlu Dai, Siyuan Cheng, Zhongliang Wang*, Ruili Zhang, Zhen Yang, Jingjing Wang, Bryant C. Yung, Zhantong Wang, Orit Jacobson, Can Xu, Qianqian Ni, Guocan Yu, Zijian Zhou, and Xiaoyuan Chen*, Hypochlorous Acid Promoted Platinum Drug Chemotherapy by Myeloperoxidase Encapsulated Therapeutic Metal Phenolic Nanoparticles, ACS Nano 2018, 12, 455-463.

[2] Yunlu Dai, Zhen Yang, Siyuan Cheng, Zhongliang Wang*, Ruili Zhang, Guizhi Zhu, Zhantong Wang, Bryant C. Yung, Rui Tian, Orit Jacobson, Can Xu, Qianqian Ni, Jibin Song, Xiaolian Sun, Gang Niu, Xiaoyuan Chen*, Toxic Reactive Oxygen Species Enhanced Synergistic Combination Therapy by Self-Assembled Metal-Phenolic Network Nanoparticles, Advanced Materials 2018, 30, 1704877. 


2017

[1] Ruili Zhang, Shi Gao ‡, Zhongliang Wang*Da Han, Lin Liu, Qingjie Ma*, Weihong Tan, Jie Tian, Xiaoyuan Chen,Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug-Resistant Cancer Cells, Advanced Functional Materials, 2017, 27,1701027.

[2] Xianghan Zhang, Bo Wang, Na Zhao, Zuhong Tian, Yunpeng Dai, Yongzhan Nie, Jie Tian, Zhongliang Wang*Xiaoyuan Chen, Efficient tumor targeting and long retention timeof NIR fluorescence probe with bioorthogonal chemistry, Theranostics, 2017, 7(15):3794-3802.

[3] Yuqiong Xia, Ruili Zhang, Zhongliang Wang*,  Jie Tian*,  Xiaoyuan Chen*, Recent Advances in High-Performance fluorescent and bioluminescent RNA Imaging Probes, Chemical Society Reviews, 2017, 46, 2824-2843.

[4] Wenting Shang, Chaoting Zeng, Yang Du, Hui Hui, Xiao Liang, Chongwei Chi, Kun Wang*, Zhongliang Wang*Jie Tian*, Core–Shell Gold Nanorod@metal–Organic framework Nanoprobes for Multi-modality Diagnosis of Glioma, Advanced Materials, 2017, 29, 1604381


2016

[1] Xiaohua Jia, Guowei Feng, Zhongliang Wang, Yang Du, Chen Shen, Hui Hui, Dong Peng, Zong-jin Li, Deling Kong, Jie Tian, Activation of mesenchymal stem cells by macrophages promotes tumor progression through immune suppressive effects, Oncotarget, 2016, 7, 20934

 

2015

[1] Xiaohua Jia, Yang Du, Duo Mao, Zhongliang Wang, Zhenqiang He, Jingdan Qiu, Xibo Ma, Wenting Shang, Dan Ding, Jie Tian*, Zoledronic Acid Prevents the Tumor-promoting effects of Mesenchymal Stem Cells  via MCP-1 Dependent Recruitment of Macrophages, Oncotarget, 2015, 6, 26018

[2] Chongwei Chi, Qian Zhang, Yamin Mao, Deqiang Kou, Jingdan Qiu, Jinzuo Ye, Jiandong Wang, Zhongliang Wang*, Yang Du*, Jie Tian*, Increased precision of orthotopic and me[ant]tastatic breast cancer surgery guided by matrix me[ant]talloproteinase activatable near-infrared fluorescence probes, Scientific Reports, 2015, 5:14197. 

[3] Zhenhua Hu, Yawei Qu, Kun Wang, Xiaojun Zhang, Jiali Zha, Tianming Song, Chengpeng Bao, Haixiao Liu, Zhongliang Wang, Jing Wang, Zhongyu Liu, Haifeng Liu*, Jie Tian*, In vivo Nanoparticle-Mediated Radiopharmaceutical-Excited Fluorescence Molecular Imaging, Nature Communications, 2015, 6:7560.

[4] Jie Yu, Wenyan Yin*, Xiaopeng Zheng, Gan Tian, Xiao Zhang, Tao Bao, Xinghua Dong, Zhongliang Wang, Zhanjun Gu*, Xiaoyan Ma*, Yuliang Zhao*, Smart MoS2/Fe3O4 Nanotheranostic for Magnetically Targeted Photothermal Therapy Guided by Magnetic Resonance/Photoacoustic Imaging, Theranostics, 2015; 5, 931-945. 

[5] Zhe Wang, Yu Wang, Zhiyong Wang, Silvio Gutkind, Zhongliang Wang, Fu Wang, Jie Lu, Gang Niu, Gaojun Teng, Xiaoyuan Chen*, Engineered Mesenchymal Stem Cells with Enhanced Tropism and Paracrine Secretion of Cytokines and Growth Factors to Treat Traumatic Brain Injury, Stem Cells, 2015, 33, 456-467.


Before 2014

[1] Zhongliang Wang, Hongyan Liu, Soon Hye Yang, Tie Wang, Chen Liu*, Y. Charles Cao*, Nanoparticle-based Artificial RNA Silencing Machinery for Antiviral Therapy, Proceedings of the National Academy of Sciences USA, 2012, 109, 12387-12392. (Highlighted by PNAS, Science-Business Exchange, ChemistryWorld Research News, Chemical & Engineering News, Phys.org, and IEEE Spectrum; Interviewed by WCJB-TV20)

[2] Zhongliang Wang, Zhe Wang, Dingbin Liu, Xuefeng Yan, Fu Wang, Gang Niu, Min Yang*, Xiaoyuan Chen*, Biomimetic RNA Silencing Nanocomplexes: Overcoming Multidrug Resistance in Cancer Cells, Angewandte Chemie International Edition, 2014, 53, 1997-2001. (Highlighted by Angew,

[3] Zhe Wang, Ruili Zhang, Zhongliang Wang*, He-fang Wang, Yu Wang, Jun Zhao, Fu Wang, Weitao Li, Gang Niu, Dale O. Kiesewetter, Xiaoyuan Chen*, Bioinspired Nanocomplexes for Spatiotemporal Imaging of Sequential mRNA ex[ant]pression in Differentiating Neural Stem Cells, ACS Nano, 2014, 8, 12386-12396.

[4] Zhongliang Wang, Ying Ma*, Ruili Zhang, Aidong Peng, Qing Liao, Zongwei Cao, Hongbing Fu, Jiannian Yao*, Reversible Luminescent Switching in a [Eu(SiW10MoO39)2]13–-Agarose Composite Film by Photosensitive Intramolecular Energy Transfer, Advanced Materials, 2009, 21, 1737-1741. 

[5] Dingbin Liu, Jie Yang, He-fang Wang, Zhongliang Wang*, Xinglu Huang, Zhantong Wang, Gang Niu, A. R. Hight Walker, Xiaoyuan Chen*, Glucose Oxidase-Catalyzed Growth of Gold Nanoparticles Enables Quantitative Detection of Attomolar Cancer Biomarkers, Analytical Chemistry, 2014, 86, 5800-5806. 

[6] Zhongliang Wang, Ruili Zhang, Ying Ma*, Aidong Peng, Hongbing Fu, Jiannian Yao*, Chemically responsive luminescent switching in transparent flexible self-supporting [EuW10O36]9–-agarose nanocomposite thin films, Journal of Materials Chemistry, 2010, 20, 271-277. 

[7] Zhongliang Wang, Ruili Zhang, Ying Ma*, Li Zheng, Aidong Peng, Hongbing Fu, Jiannian Yao*, Transparent and Flexible phosphomolybdate-agarose composite thin films with visible-light photochromism, Journal of Materials Chemistry, 2010, 20, 1107-1111. 

[8] Zhongliang Wang, Zhen Hui Kang, En Bo Wang*, Zhongmin Su, Lin Xu, Intercalation and photophysical properties of the tetra-(8-hydroxyquinolinato) boron complex and 3,3',4,4'-benzophenone tetracarboxylic anion into Mg-Al layered double hydroxides, Inorganic Chemistry, 2006, 45, 4364-4371. 

[9] Tie Wang, Jiaqi Zhuang, Jared Lynch, Ou Chen, Zhongliang Wang, Xirui Wang, Derek LaMontagne, Huimeng Wu, Zhongwu Wang, Y. Charles Cao*, Self-assembled colloidal superparticles from nanorods, Science, 2012, 338, 358-363. 

[10] Tie Wang, Xirui Wang, Derek LaMontagne, Zhongliang Wang, Zhongwu Wang, Y. Charles Cao*, Shape-controlled Synthesis of Colloidal Superparticles from Nanocubes, Journal of the American Chemical Society, 2012, 134, 18225-18228.