【主持科研项目】:
(1) 山东省自然科学基金面上项目(ZR2023MB136)，10万，2024.01-2026.12，在研；
(2) 山东省自然科学基金面上项目(ZR2019MB003)，20万，2019.07-2022.06，已结题；
(3) 山东省重点研发计划(2018GGX109010)，12万，2018.03-2020.02，已结题；
(4) 山东省自然科学基金(ZR2015BL006)，3万，2015.08-2017.08，已结题。
(5) 山东省医药卫生科技发展计划(202213050542)，2023.01-2024.12，已结题。
(6) 泰安市科技创新发展项目(2022NS306)，2022.11-2014.11，已结题。
(7) 泰安市科技发展计划(2015GX2049)，2015-2017，已结题。
【近年代表性论文】:（第一作者#或通讯作者*论文）
(18) Kai-Qiang Tian(#), Shi-Jiao Zhang(#), Jun Zhao, Gui-Yun Duan, Qiao-Ling Wang, Guo-Hao Cui, Rui Guo(*), Hong-Shuang Li(*). “Regio- and Diastereoselective Highly Strained Alkylidenecyclobutane Isomerization/Hydroacylation: Synthesis of Multisubstituted Cyclobutanes with Consecutive Stereocenters.” ACS Catal., 2024, 14, 1505−1513. (IF = 11.3)
Highlighted by CBG咨讯：山东第一医科大学李洪爽课题组ACS Catal.
(17) Jun Zhao(#), Wen-Jing Yang(#), Yuan-Yi Lu, Yu Teng, Shi-Chao Lu(*), Hong-Shuang Li(*). “Regioselective construction of 2-substituted indolines enabled by a rhodium-catalyzed decarboxylation−hydroacylation sequence.” Org. Chem. Front., 2024, 11, 5495−5501. (IF = 4.6)
Highlighted by Frontiers Journals：山东第一医科大学李洪爽团队 | 铑催化的脱羧–氢酰化反应区域选择性构建2-取代吲哚啉
(16) Jun Zhao(#), Yuan-Yi Lu(#), Rui Wang, Patience Peters, Hong-Shuang Li(*). “Rhodium(I) Catalyzed Hydroacylation Reactions of Alkenyl Compounds.” Adv. Synth. Catal., 2024, 366, 1707−1718. (IF = 4.4)
(15) Zhi-Ping Jiang(#), Ying-Yun Li, Jun Zhao, Shi-Jiao Zhang(*), Hong-Shuang Li(*). “Ligand-Controlled Regioselective Hydroacylation Reactions of Methylenecyclobutanes under Rhodium Catalysis.” ChemistrySelect, 2024, 9, e202403892. (IF = 1.9)
(14) Kai-Qiang Tian(#), Tongbo Zhang(#), Shi-Jiao Zhang, Jun Zhao, Leilei Mao(*), Guiyun Duan(*), Hong-Shuang Li(*). “A regioselective, convergent, and additive-free approach for the synthesis of pyrido[1,4]oxazocines.” New J. Chem., 2023, 47, 18193−18198. (IF = 2.7)
(13) Fei-Yuan Gong(#), Gui-Li Guo(#), Zhi-Xin Chang, Xue-Ming Lu, Fu-Gang Wang, Lei Wang(*), Hong-Shuang Li(*). “Rhodium-Catalyzed Decarboxylative Hydroacylation of Vinylethylene Carbonates for Regioselective Ester Synthesis.” Adv. Synth. Catal., 2022, 364, 1757−1762. (IF = 5.4)
(12) Fu-Gang Wang(#), Fei-Yuan Gong(#), Juan Cao, Ji-Cong Wang, Kai-Qiang Tian, Jinbo Zhao(*), Hong-Shuang Li(*). “Rh(I)-catalyzed site-selective hydroacylation of alkenyl-bearing allylic alcohols with non-chelating aldehydes controlled by in situ generated carbonyl group.” New J. Chem., 2022, 46, 19802−19807. (IF = 3.3)
(11) Zhi-Xin Chang(#), Fei-Yuan Gong(#), Xiaodan Wang, Tongbo Zhang, Junfen Han(*), Hong-Shuang Li(*). “Rhodium-Catalyzed Regioselective Formal Hydroacylation of Vinyl Epoxides toward Esters Involving β-Carbon Cleavage.” Org. Lett., 2021, 23, 6084−6089. (IF = 6.072)
(10) Zhi-Xin Chang(#), Fu-Rong Li(*), Chengcai Xia, Fei Li, Hong-Shuang Li(*). “Regioselective Access to 3-Ethylideneflavanones via Rhodium(I)-Catalyzed 1,3-Enyne Hydroacylation/Annulation Cascades.” Adv. Synth. Catal., 2021, 363, 1722−1726. (IF = 5.981)
(9) Guirong You(#), Zhi-Xin Chang, Jizhong Yan(*), Chengcai Xia, Fu-Rong Li, Hong-Shuang Li(*). “Rhodium-catalyzed sequential intermolecular hydroacylation and deconjugative isomerization toward diversified diketones.” Org. Chem. Front., 2021, 8, 39−45. (IF = 5.456)
(8) Hong-Shuang Li(#)(*), Shi-Chao Lu(#), Zhi-Xin Chang, Liqiang Hao, Fu-Rong Li, Chengcai Xia. “Rhodium-Catalyzed Ring-Opening Hydroacylation of Alkylidenecyclopropanes with Chelating Aldehydes for the Synthesis of γ,δ-Unsaturated Ketones.” Org. Lett., 2020, 22, 5145−5150. (IF = 6.005)
(7) Shi-Chao Lu(#), Zhi-Xin Chang(#), Yu-Liang Xiao, Hong-Shuang Li(*). “Regio- and Stereoselective Synthesis of 2-Hydroxymethyl-1,3-enynes by Rhodium-Catalyzed Decarboxylative C−C Coupling.” Adv. Synth. Catal., 2019, 361, 4831–4836. (IF = 5.851)
(6) Hong-Shuang Li(#)(*), Guili Guo, Rui-Ze Zhang, Fei Li. “Rhodium-Catalyzed Synthesis of α,β-Unsaturated Ketones through Sequential C−C Coupling and Redox Isomerization.” Org. Lett., 2018, 20, 5040−5043. (IF = 6.555)
(5) Hong-Shuang Li(#), Yang Xiong(#), Guozhu Zhang(*). “Rhodium-Catalyzed Annulations of 1,3-Dienes and Salicylaldehydes/2-Hydroxybenzyl Alcohols Promoted by 2-Ethylacrolein.” Adv. Synth. Catal., 2018, 360, 4246−4251. (IF = 5.451)
(4) Shi-Chao Lu(#), Hong-Shuang Li(*), Ya-Ling Gong, Shi-Peng Zhang, Ji-Guo Zhang, Shu Xu(*). “Combination of PhI(OAc)2 and 2-Nitropropane as the Source of Methyl Radical in Room-Temperature Metal-Free Oxidative Decarboxylation/Cyclization: Construction of 6-Methyl Phenanthridines and 1-Methyl Isoquinolines.” J. Org. Chem., 2018, 83, 15415−15425. (IF = 4.745)
(3) Shi-Chao Lu(#), Hong-Shuang Li(*), Shu Xu, Gui-Yun Duan. “Silver-catalyzed C2-selective direct alkylation of heteroarenes with tertiary cycloalkanols.” Org. Biomol. Chem., 2017, 15, 324−327. (IF = 3.423)
(2) Shi-Chao Lu(#), Hong-Shuang Li(*), Ya-Ling Gong, Xiao-Lei Wang, Fu-Rong Li, Fei Li, Gui-Yun Duan, Shu Xu(*). “Use of unprotected amino acids in metal-free tandem radical cyclization reactions: divergent synthesis of 6-alkyl/acyl phenanthridines.” RSC Adv., 2017, 7, 55891−55896. (IF = 2.936)
(1) Hong-Shuang Li(#), Gang Liu(*). “Copper/Silver-Mediated Cascade Reactions for the Construction of 2-Sulfonylbenzo[b]furans from trans-2-Hydroxycinnamic Acids and Sodium Sulfinates.” J. Org. Chem., 2014, 79, 509−516. (IF = 4.721)
【授权发明专利】
(1) 李洪爽; 张瑞泽; 夏成才; 段桂运. “一种四氢苯并噻唑-2-丙酮肟衍生物及其制备方法和应用(ZL201711362809.9).” 授权公告日: 2021年02月12日; 授权公告号: CN107868063B.
(2) 李洪爽; 田恩沛; 赵俊; 鲁缘怡. “一种1-芳基-2-(吲哚啉-2-基)乙酮类化合物的制备方法.” 专利申请号：202410244820.9.
(3) 李洪爽; 王雨晴; 田凯强; 赵俊. “一种吡啶并[3,4-g][1,4]噁佐辛类化合物及其制备方法和应用.” 专利申请号：202410245176.7.