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成果及论文

代表论文(卢智刚)

1Chen, C., Hao, X., Lai, X., Liu, L., Zhu, J., Shao, H., Huang, D., Gu, H., Zhang, T., Yu, Z., Xie, L., Zhang, X., Yang, Y., Xu, J.*, Zhao, Y.*, Lu, Z.*, and Zheng, J.* (2021) Oxidative phosphorylation enhances the leukemogenic capacity and resistance to chemotherapy of B cell acute lymphoblastic leukemia. Science Advances 7, eabd6280. (共同通讯作者)

2Yunqing Gu, Jun Cao, Xinyu Zhang, Hai Gao, Yuyan Wang, Jia Wang, Jinlan Zhang, Guanghui Shen, Xiaoyi Jiang, Jie Yang, Xichen Zheng, Jianqing Xu, Cheng Cheng Zhang, Fei Lan, Di Qu, Yun Zhao, Guoliang Xu, Youhua Xie, Min Luo, Zhigang Lu. Interaction network of SARS-CoV-2 with host receptome through spike protein. BioRixv, https://doi.org/10.1101/2020.09.09.287508. (共同通讯作者

3Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, He L, Chen Y, Chen H, Luo W, Lu Z, Xie J, Churchill H, Xu Y, Zhou Z, Wu G, Yu C, John S, Hirayasu K, Nguyen N, Liu X, Huang F, Li L, Deng H, Tang H, Sadek A. H, Zhang L, Huang T, Zou Y, Chen B, Zhu H, Arase H, Xia N, Jiang Y, Collins R, You M. J, Homsi J, Unni N, Lewis C, Chen G. Q, Fu Y. X, Liao X. C, An Z, Zheng J, Zhang N, Zhang C. C. LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. Nature 2018, 562 (7728), 605-609.

4Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC. Fasting selectively blocks acute lymphoblastic leukemia development via leptin receptor upregulation. Nature Medicine. 2017. 23(1): 79-90. (共同通讯作者)

5Nakada, Y., Canseco D. C., Thet S., Abdisalaam S., Asaithamby A., Santos C. X., Shah A., Zhang H., Faber J. E., Kinter M. T., Szweda L. I., Xing C., Deberardinis R., Oz O., Lu Z., Zhang C. C., Kimura W. and Sadek H. A.. Hypoxia induces heart regeneration in adult mice. Nature. 2017. 541(7636): 222-227.

6Luo M., Wang H., Wang Z., Cai H., Lu Z., Huang G., Chen X., Porembka M., Frankel A, Chen ZJ, Gao J. A STING-activating nanovaccine for cancer immunotherapy. Nat Nanotechnoloty. doi:10.1038/nnano.2017.52. 2017.

7Kimura, W., Xiao F., Canseco D. C., Muralidhar S., Thet S., Zhang H. M., Abderrahman Y., Chen R., Garcia J. A., Shelton J. M., Richardson J. A., Ashour A. M., Asaithamby A., Liang H., Xing C., Lu Z., Zhang C. C. and Sadek H. A: Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart. Nature, 2015, 523(7559): 226-230.

8Kang X, Lu Z, Cui C, Deng M, Fan Y, Dong B, Han X, Xie F, Tyner JW, Coligan JE, Collins RH, Xiao X, You MJ, Zhang C.C: The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development. Nature Cell Biology, 2015; 17(5): 665–677.

9Deng M*, Lu Z*, Zheng J, Wan X, Chen X, Hirayasu K, Sun H, Lam Y, Chen L, Wang Q, Song C, Huang N, Gao G.F, Jiang Y, Arase H, and Zhang C.C. A motif in LILRB2 critical for Angptl2 binding and activation. Blood. 2014. 924 - 935. (共同一作)

10Zheng J.*, Lu Z.*, Kocabas F., Bottcher R. T., Costell M., Kang X., Liu X., Deberardinis R. J., Wang Q., Chen G., Sadek H., Zhang C. C. Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow. Blood. 2014. 123(7):992-1001. (共同一作)

11Luo M., Ling T., Xie W., Sun H., Zhou Y., Zhu Q., Shen M., Zong L., Lyu G., Zhao Y., Ye T., Gu J., Tao W.#, Lu Z.#, Grummt I#. NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells. 2013; 31:1278-1286. (共同通讯作者)

12Ling T., Xie W., Luo M., Shen M., Zhu Q., Zong L., Zhou T., Gu J., Lu Z. #, Zhang F. #, Tao W#. CHD4/NuRD maintains demethylation state of rDNA promoters through inhibiting the expression of the rDNA methyltransferase recruiter TIP5. Biochem Biophys Res Commun. 2013;437:101-107. (共同通讯作者)

13Meng S, Luo M, Sun H, Yu X, Shen ML, Zhang QC, Zhou RD, Ju XF, Tao W, Liu D#, Deng HK#, Lu Z#. Identification and characterization of Bmi-1 responding element within the human p16 promoter. Journal of Biological Chemistry. 285, 33219-33229. 2010. (共同通讯作者)

14Luo M, Lu ZY, Sun H, Yuan KH, Zhang QC, Meng S, Wang FX, Guo HC, Ju XF, Liu YQ, Ye T, Lu Z#, Zhai Z. Nuclear entry of active caspase-3 is facilitated by its p3-recognition-based spacific cleavage activity. Cell Research. 20:211-222. 2010. (通讯作者)

15Lu Z, Zhang CM, Zhai Z. Nucleoplasmin regulates chromatin condensation during apoptosis. Proc. Natl. Acad. Sci. USA. 102(8): 2778-2783. 2005

 

   

代表论文(罗敏)

1.Li S, Luo M, Wang Z, Fu YX, Baran S, Yu H , Gao J. Prolonged activation of innate immune pathways by a polyvalent STING agonist. Nature Biomedical Engineering. 2021 May; 5(5):455-466.

2.Gu Y, Cao J, Zhang X, Gao H, Wang Y, Wang J, Jiang X, Zhang J, Shen G, Yang J, Zheng X, Xu J, Lan F, Qu D, Zhao Y, Xu G, Xie Y*, Luo M*, Lu Z* (2020). Interaction network of SARS-CoV-2 with host receptome through spike protein. bioRxiv, https://doi.org/10.1101/2020.09.09.287508. (共同通讯作者)

3.Yin WM, Li YW, Gu YQ, Luo M*. Nanoengineered targeting strategy for cancer immunotherapy. Acta Pharmacol Sin. 2020 Jul;41(7):902-910. (通讯作者)

4.Miller J, Luo M, ChenZJ, Gao J, Zhao T. ONM-500 – a novel STING-activating therapeutic nanovaccine platform for cancer immunotherapy. Journal For Immunotherapy of Cancer , 2020 April;8(A7-A8).

5.Luo M, Liu ZD, Fu Yang-Xin, Gao Jinming. Synergistic STING activation by PC7A nanovaccine and ionizing radiation improves cancer immunotherapy, Journal of Controlled Release, 2019, 300154-160.

6.Luo M., Wang H., Wang Z., Cai H., Lu Z., Huang G., Chen X., Porembka M., Frankel A, Zhijian J. Chen, Gao J. A STING-activating nanovaccine for cancer immunotherapy. Nat Nanotechnoloty. 12(7):648-654, 2017.

7.Luo M, Layla Z. Samandi, Zhaohui Wang, Zhijian J. Chen and Jinming Gao, Synthetic nanovaccines for T cell immunotherapy, Journal of Control Release. 263:200-210, 2017, (Invited review)

8.Wang Z.*, Luo M.*, Mao C., Wei Q., Zhao T., Li Y., Huang G., and Gao J. A Redox Activatable Fluorescent Sensor for the High-Throughput Quantification of Cytosolic Delivery of Macromolecules. Angew. Chem. 2017. 129:1339-1343.

9.Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC. Fasting selectively blocks acute lymphoblastic leukemia development via leptin receptor upregulation. Nature Medicine. 2017. 23(1): 79-90.

10.Zhao T., Huang G., Li Y., Yang S., Ramezani S., Lin Z., Wang Y., Ma X., Zeng Z., Luo M., Boer E., Xie X., Thibodeaux J., Brekken RA, Sun X., Sumer BD, Gao J. A transistor-like pH nanoprobe for tumor detection and image-guided surgery. Nature Biomed. Eng. 2016, DOI: 10.1038/s41551-016-0006.