科研项目:
1. 国家自然科学基金优秀青年科学基金项目(海外)项目(项目负责人,2023-2025);
2. 湖北省引进海外高层次人才百人计划(项目负责人,2022);
3. 国家自然科学基金青年基金(项目负责人,21702150)
Publications in WHU:
1. Zhenghui Huang, Zihan Yu, Zhaogang Guo, Pingsen Shi, Jingcheng Hu, Hongbing Deng*, Zhiliang Huang*. Selective Cleavage of Cβ−O−4 Bond for Lignin Depolymerization via Paired-Electrolysis in an Undivided Cell. Angew. Chem. Int. Ed. 2024.
2. Zhiliang Huang, Yanming Su, Ganfei Zeng, and Beibei Tan; “Comprehensive Organic Synthesis, Volume 7: Oxidation; Oxidation of Biomass”. Edited by Aiwen Lei. ELSEVIER: 2024.
Ph.D. and Postdoc Publications:
1. Yongli Li, Huamin Wang, Zhuning Wang, Hesham Alhumade, Zhiliang Huang*, and Aiwen Lei*; “Electrochemical radical-mediated selective C(sp3)–S bond activation”; Chem. Sci. 2023, 14, 372-378.
2. Renpeng Guan, Guanhong Chen, Sam Haq, Elliot L. Bennett, Zhiliang Huang*, and Jianliang Xiao*; “Chemoselective Decarboxylative Oxygenation of Carboxylic Acids to Access Ketones, Aldehydes, Alcohols and Peroxides”; Org. Lett. 2023, 25, 14, 2482–2486.
3. Zhiliang Huang, Muralidharan Shanmugam, Zhao Liu, Adam Brookfield, Elliot L. Bennett, Renpeng Guan, David E. Vega Herrera, Jose A. Lopez-Sanchez, Anna G. Slater, Eric J. L. McInnes*, Xiaotian Qi*, and Jianliang Xiao*; “Chemical Recycling of Polystyrene to Valuable Chemicals via Selective Acid-Catalyzed Aerobic Oxidation under Visible Light”; J. Am. Chem. Soc. 2022, 144, 14, 6532–6542. (Highly cited paper, featured in JACS Spotlights, C&EN and ChemistryViews)
4. Zhaoliang Yang,† Dali Yang,† Jianye Zhang, Chenyu Tan, Jiajun Li, Shengchun Wang, Heng Zhang, Zhiliang Huang*, and Aiwen Lei*; “Ce-Catalyzed Ring-Opening Functionalization of Cycloalkanols under Redox-Neutral Condition: Scope and Mechanism”; J. Am. Chem. Soc. 2022, 144, 30, 13895–13902.
5. Shengzhang Liu,† Shengchun Wang,† Pengjie Wang, Zhiliang Huang*, Tao Wang*, and Aiwen Lei*; “Electro-oxidative Intermolecular 1,2-Aminoxygenation of Alkenes with Hydrogen Evolution”; Nature Commun. 2022, 13, 4430.
6. Daoxin Wang, Tengfei Jiang, Hao Wan, Ziyue Chen, Junchao Qi, Anqi Yang, Zhiliang Huang*, Yong Yuan*, and Aiwen Lei*; “Alternating Current Electrolysis Enabled Formal C−O/O−H Cross-Metathesis of 4-Alkoxy Anilines with Alcohols. ”; Angew. Chem. Int. Ed. 2022, 61, e202201543.
7. Zhipeng Guan,† Shuxiang Zhu, † Yayu Ye, Xiangwei Li, Yanlong Liu, Pengjie Wang, Heng Zhang*, Zhiliang Huang*, and Aiwen Lei*; “Synthesis of Cyclopentene Derivatives via Electrochemical-Induced Intermolecular Selective (3+2) Annulation”; Angew. Chem. Int. Ed. 2022, 61, e202207059.
8. Zhiliang Huang, Renpeng Guan, Elliot L. Bennett, and Jianliang Xiao*; “A Non-Heme Manganese(II) Complex Catalyzed Aerobic Oxidative Cleavage of 1,2-Diols via O2 Activation”; Green Chem. 2022, 24, 3814-3823.
9. Renpeng Guan, Elliot L. Bennett, Zhiliang Huang*, and Jianliang Xiao*; “Decarboxylative Oxygenation of Carboxylic Acids with O2 via a Non-Heme Manganese Catalyst”; Green Chem. 2022, 24, 2946-2952.
10. Mingming Yu, Yuhan Gao, Lin Zhang, Yingjie Zhang, Yiyan Zhang, Hong Yi, Zhiliang Huang*, and Aiwen Lei*; “Electrochemical-induced benzyl C–H amination towards the synthesis of isoindolinones via aroyloxy radical-mediated C–H activation”; Green Chem. 2022, 24, 1445-1450.
11. Zhipeng Guan, Xingxing Zhong, Yayu Ye, Xiangwei Li, Hengjiang Cong, Hong Yi, Heng Zhang, Zhiliang Huang*, and Aiwen Lei*; “Selective Radical Cascade (4+2) Annulation with Olefins towards the Synthesis of Chroman Derivatives via Organo-Photoredox Catalysis”; Chem. Sci. 2022, 13, 6316-6321.
12. Xingxiu Yan, Shengchun Wang, Zhao Liu, Yujie Luo, Pengjie Wang, Wenyan Shi, Xiaotian Qi*, Zhiliang Huang*, and Aiwen Lei*; “Precise electro-reduction of alkyl halides for radical defluorinative alkylation”; Sci. China Chem. 2022, 65, 762–770.
13. Zhiliang Huang, Renpeng Guan, Muralidharan Shanmugam, Elliot L. Bennett, Craig M. Robertson, Adam Brookfield, Eric J. L. McInnes and Jianliang Xiao*; “Oxidative Cleavage of Alkenes by O2 with a Non-Heme Manganese Catalyst”; J. Am. Chem. Soc. 2021, 143, 26, 10005–10013. (Highly cited paper)
14. Zhiliang Huang, Dongchao Zhang, Jyh-Fu Lee*, and Aiwen Lei*; “Elucidating the Structure of a High-Spin σ-Phenyliron(III) Species in Live FeCl3-PhZnCl Reaction System”; Chem. Commun., 2018, 54, 1481-1484.
15. Zhiliang Huang, Xiaotian Qi, Jyh-Fu Lee*, and Aiwen Lei*; “Revealing the Structure and Reactivity of the Active Species in the FeCl2–TBHP System: Case Study on Alkene Oxidation”; Organometallics, 2018, 37, 1635-1640.
16. Yong Yuan, Yi Yu, Jin Qiao, Pan Liu, Banying Yu, Wukun Zhang, Huilin Liu, Min He, Zhiliang Huang*, and Aiwen Lei*; “Exogenous-Oxidant-Free Electrochemical Oxidative C–H Sulfonylation of Arenes/Heteroarenes with Hydrogen Evolution”; Chem. Commun., 2018, 54, 11471-11474.
17. Caihong Zheng, Fangling Lu, Hanwei Lu, Jie Xin, Yi Deng, Dali Yang, Shengchun Wang, Zhiliang Huang*, Meng Gao*, and Aiwen Lei*; “Copper-Catalyzed Selective Radical–Radical Cross-Coupling for C–S Bond Formation: An Access to α-Alkylthionitriles”; Chem. Commun., 2018, 54, 5574-5577.
18. Li Sun, Anjin Yao, Haiyan Wang, Limei Zhang, Lizhen Zeng, Zhiliang Huang*, Meng Gao*, and Aiwen Lei*; “Oxidation-Induced para-Selective Formylation of N,N-Substituted Aniline”; Asian J. Org. Chem. 2018, 7, 1571-1574.
19. Yong Yuan, Yixuan Chen, Shan Tang, Zhiliang Huang, and Aiwen Lei*; “Electrochemical oxidative oxysulfenylation and aminosulfenylation of alkenes with hydrogen evolution”; Sci. Adv. 2018, 4:eaat5312.
20. Dongchao Zhang, Zhiliang Huang*, and Aiwen Lei*; Oxidation-Induced Ortho-Selective C–H Bond Functionalization of 2-Naphthylamine Derivative. Sci. China Chem. 2018, 61, 1274–1277.
21. Yong Yuan, Yangmin Gao, Yueping Lin, Yongli Li, Zhiliang Huang, and Aiwen Lei*; “Electrochemical oxidative alkoxysulfonylation of alkenes using sulfonyl hydrazines and alcohols with hydrogen evolution”; ACS Catal. 2018, 8, 10871-10875.
22. Haiming Yan, Ying Zhao, Zhiliang Huang*, and Aiwen Lei*; “Elemental Sulfur as a Sulfuration Agent in the Copper-Catalyzed C–H Bond Thiolation of Electron-Deficient Arenes”; Org. Biomol. Chem., 2017, 15, 8276-8279.
23. Kun Wu, Lingkui Meng, Mingming Huai, Zhiliang Huang, Chao Liu, Xiaotian Qi, and Aiwen Lei*; “Palladium-catalyzed aerobic (1+2) annulation of Csp3–H bonds with olefin for the synthesis of 3-azabicyclo[3.1.0]hex-2-ene”; Chem. Commun., 2017, 53, 2294-2297.
24. Zhiliang Huang, Dongchao Zhang, Xiaotian Qi, Zhiyuan Yan, Mengfan Wang, Haiming Yan, and Aiwen Lei*; “Radical-Radical Cross-Coupling for C-S Bond Formation”; Org. Lett. 2016, 18, 2351-2354.
25. Ying Zhao, Haiming Yan, Hanwei Lu, Zhiliang Huang*, and Aiwen Lei*; “Para-Selective C-H Functionalization of Iodobenzenes”; Chem. Commun., 2016, 52, 11366-11369.
26. Guanghui Zhang, Hong Yi, Jie Xin, Yi Deng, Ruopeng Bai, Zhiliang Huang, Jeffrey T. Miller, A. Jeremy Kropf, Emilio E. Bunel, Xiaotian Qi, Yu Lan* and Aiwen Lei*; “Aromatic C–H bond cleavage by using a Cu(I) ate-complex”; Org. Chem. Front., 2016, 3, 975-978.
27. Kun Wu, Zhiliang Huang, Yiyang Ma and Aiwen Lei*; “Copper-catalyzed and iodide-promoted aerobic C–C bond cleavage/C–N bond formation toward the synthesis of amides”; RSC Adv., 2016, 6, 24349-24352.
28. Kun Wu,† Zhiliang Huang,† Xiaotian Qi, Yingzi Li, Guanghui Zhang, Chao Liu, Hong Yi, Lingkui Meng, Emilio E. Bunel, Jeffrey T. Miller, Chih-Wen Pao, Jyh-Fu Lee, Yu Lan*, Aiwen Lei*; “Copper-catalyzed aerobic oxidative coupling: From ketone and diamine to pyrazine”; Sci. Adv. 2015;1:e1500656.
29. Kun Wu, Zhiliang Huang, Chao Liu, Heng Zhang, and Aiwen Lei*; “Aerobic C-N Bond Activation: A Simple Strategy to Construct Pyridines and Quinolines”; Chem. Comm. 2015, 51, 2286-2289.
30. Qingquan Lu, Jian Zhang, Pan Peng, Guanghui Zhang, Zhiliang Huang, Hong Yi, Jeffrey T. Miller*, Aiwen Lei*, “Operando X-ray absorption and EPR evidence for a single electron redox process in copper catalysis”; Chem. Sci., 2015, 6, 4851-4854.
31. Ruopeng Bai, Guanghui Zhang, Hong Yi, Zhiliang Huang, Xiaotian Qi, Chao Liu, Jeffrey T Miller, Arthur Jeremy Kropf, Emilio E Bunel*, Yu Lan*, and Aiwen Lei*; “Cu(II)/Cu(I)-Synergistic Cooperation to Lead the Alkyne C-H Activation”; J. Am. Chem. Soc. 2014, 136, 16760-16763.
32. Zhiliang Huang, Liqun Jin, Ye Feng, Pan Peng, Hong Yi, and Aiwen Lei*; “Iron-Catalyzed Oxidative Radical Cross-Coupling/Cyclization between Phenols and Olefins”; Angew. Chem. Int. Ed. 2013, 52, 7151-7155.
33. Zhiliang Huang,† Liqun Jin,† Heyou Han*, and Aiwen Lei*; “The ‘Kinetic Capture’ of an Acylium Ion From Live Aluminum Chloride Promoted Friedel–Crafts Acylation Reactions”; Org. Biomol. Chem., 2013, 11, 1810-1814.
34. Cangbai Qiu, Liqun Jin, Zhiliang Huang, Zhenquan Tang, Aiwen Lei*, Zhenlu Shen, Nan Sun, Weimin Mo, Baoxiang Hu, and Xinquan Hu*; “Symbiotic Catalysis Relay: Molecular Oxygen Activation Catalyzed by Multiple Small Molecules at Ambient Temperature and its Mechanism”; ChemCatChem 2012, 4, 76-80.
35. Zhiliang Huang, Liqun Jin, Aiwen Lei*; “Development of Mechanism Studies and Kinetic Investigations in Friedel-Crafts Acylation”; Chin. J. Org. Chem., 2011, 31, 775-783.
36. Liqun Jin, Jie Xin, Zhiliang Huang, Jun He, and Aiwen Lei*; “Transmetalation is the Rate-Limiting Step: Quantitative Kinetic Investigation of Nickel-Catalyzed Oxidative Coupling of Arylzinc Reagents”; J. Am. Chem. Soc. 2010, 132, 9607-9609.