【个人简历】
2010.09-2014.06 上海师范大学 生物与环境科学学院,学士
2014.09-2016.06 复旦大学 生物医学研究院,硕士
2016.09-2019.06 复旦大学 生物医学研究院,博士
2019.07-2021.10 复旦大学 附属肿瘤医院, 博士后
2021.10至今 复旦大学 生物医学研究院,青年副研究员
【研究方向】
肿瘤发生、发展的表观遗传学(染色质重塑、转录因子、RNA结合蛋白以及肿瘤特异转录本在癌症中的功能与机理)、肿瘤治疗(小分子抑制剂、寡核苷酸)
【个人邮箱】
zhixiang211@126.com
【发表论文】
Zhixiang Hu#, Liangqing Dong#, Shengli Li, Zhe Li, Yejun Qiao, Yuchen Li, Jie Ding, Zhiao Chen, Yangjun Wu, Zhen Wang, Shenglin Huang, Qiang Gao*, Yingjun Zhao*, Xianghuo He*. Splicing Regulator p54nrb/NONO Enhances Carcinogenesis Through Oncogenic Isoform Switch of BIN1 in Hepatocellular Carcinoma. HEPATOLOGY, 2019, doi: 10.1002/hep.31062.
Weijie Guo#, Zhixiang Hu#, Yichao Bao, Yuchen Li, Shengli Li, Qiupeng Zheng, Dongbin Lyu, Di Chen, Tao Yu, Yan Li, Xiaodong Zhu, Jie Ding, Yingjun Zhao, Xianghuo He* and Shenglin Huang*.A LIN28B Tumor-Specific Transcript in Cancer. Cell Reports, 22 (2018) 2016-2025.
Qin Li#, Hongyan Lai#, Yuchen Li, Bing Chen, Siyuan Chen, Yan Li, Zhaohui Huang, Zhiqiang Meng, Peng Wang, Zhixiang Hu*, Shenglin Huang*. RJunBase: a database of RNA splice junctions in human normal and cancerous tissues. Nucleic Acids Research. 2020 Nov 12;gkaa1056.
Shengli Li, Zhixiang Hu, Yingjun Zhao, Shenglin Huang, Xianghuo He*. Transcriptome-Wide Analysis Reveals the Landscape of Aberrant Alternative Splicing Events in Liver Cancer. HEPATOLOGY, 2018, 69 (1), 359-375.