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成果及论文

Publications @ NJTech 

31. Qi-Chao Shan#, You-Wei Wu#, Mu-Xiang Chen, Xuefei Zhao, Teck-Peng Loh*Xu-Hong Hu*. Synergistic Copper-Aminocatalysis for Direct Tertiary α-Alkylation of Ketones with Electron-Deficient Alkanes. 

Adv. Sci. 2024, 11, 2402255.

30. You-Wei Wu, Mu-Xiang Chen, Yan Li, Lu-Min Hu, Lili Zhao, Zhenhua Jia,  Xuefei Zhao*Xu-Hong Hu*. A Catalyst-Free Cross-Coupling of Isocyanates and Triarylboranes for Secondary Amide Synthesis. 

Org. Chem. Front. 2024, 11, 364-369.

29. Jia-Bao Li, Lan-Tu Xiong, Yan-Rong Lu, Yu-Qing Zhang, Xiao-Li Xu, Hai-Hong Wang, Xin Deng, Xu-Hong Hu*, Zi-Ning Cui*. Novel pyrimidin-4-one derivatives as potential T3SS inhibitors against Xanthomonas campestris pv. campestris.

Pest Manag. Sci. 2023, 79, 3666–3675.

28. Xing Zhang, Tian-Ming Yang, Lu-Min Hu, Xu-Hong Hu*. Stereoselective Iron-Catalyzed Alkylation of Enamides with Cyclopropanols via Oxidative C(sp2)−H Functionalization.

Org. Lett. 2022, 24, 8677−8682.

 (Highlighted by CBG)

27. Ya Gao, Wei QinMing-Qing Tian, Xuefei Zhao* and Xu-Hong Hu*. Defluorinative Alkylation of Trifluoromethyl Alkenes with Soft Carbon Nucleophiles Enabled by a Catalytic Amount of Base.

 Adv. Synth. Catal. 2022, 364, 2241– 2247.

 (Highlighted by 今日论文)

26. Qi-Chao ShanLu-Min HuWei Qin, and Xu-Hong Hu*. Copper-Catalyzed Cross-Nucleophile Coupling of β-Allenyl Silanes with Tertiary C–H Bonds: A Radical Approach to Branched 1,3-Dienes.

 Org. Lett202123, 6041−6045.

 (Highlighted by CBG)

25. Ming-Qing Tian#, Zhen-Yao Shen#, Xuefei Zhao, Patrick J. Walsh*, and Xu-Hong Hu*. Iron-Catalyzed Tertiary Alkylation of Terminal Alkynes with 1,3-Diesters via a Functionalized Alkyl Radical. 

  Angew. Chem. Int. Ed. 202160, 9706-9711.

24. Rui-Hua Liu#, Qi-Chao Shan#, Ya Gao, Teck-Peng Loh*, Xu-Hong Hu*. Access to Multi-Functionalized Oxazolines via Silver-Catalyzed Heteroannulation of Enamides with Sulfoxonium Ylides. 

  Chin. Chem. Lett202132, 1411–1414.

23. Song Li, Qi-Chao Shan, Lu-Min Hu, Xue-Qing Ma, Xu-Hong Hu*.  Merging Alkenyl C–H Activation With the Ringopening of 1,2-Oxazetidines: Ruthenium-Catalyzed Aminomethylation of Enamides. 

  Chem. Commun. 202056, 7969-7972.

22. Rui-Hua Liu, Zhen-Yao Shen, Cong Wang, Teck-Peng Loh, Xu-Hong Hu*. Selective Dehydrogenative Acylation of Enamides with Aldehydes Leading to Valuable β- Ketoenamides. 

  Org. Lett. 202022, 944-949. 

 (Highlighted by Organic Chemistry Portal)

21. Pengfei Shi, Song Li, Lu-Min Hu, Cong Wang, Teck-Peng Loh*Xu-Hong Hu*. The Ruthenium-Catalyzed C-H Functionalization of Enamides with Isocyanates: Easy Entry to Pyrimidin-4-Ones. 

  Chem. Commun. 201955, 11115-11118.

20. Zhen-Yao Shen#, Jun-Kee Cheng#, Cong Wang, Chao Yuan, Teck-Peng Loh*Xu-Hong Hu*. Iron-Catalyzed Carbamoylation of Enamides with Formamides as a Direct Approach to N-Acyl Enamine Amides. 

  ACS Catal20199, 8128-8135. 

 (Highlighted by X-Mol)

19. Rui-Hua Liu, Qi-Chao Shan, Xu-Hong Hu*, Teck-Peng Loh*. Site-Selective C(sp3)–H Amination of Thioamide with Anthranils under Cp*CoIII Catalysis. 

  Chem. Commun. 201955, 5519-5522.

18. Ming-Qing Tian, Cong Wang, Xu-Hong Hu*, Teck-Peng Loh*. Divergent C-H Oxidative Radical Functionalization of Olefins to Install Tertiary Alkyl Motifs Enabled by Copper Catalysis.

  Org. Lett. 201921, 1607-1611. 

 (Highlighted by Synfacts 2019, 15, 524)

17. Song Li, Pengfei Shi, Rui-Hua Liu, Xu-Hong Hu*, Teck-Peng Loh*. Cobalt-Catalyzed N-O and C-C Bond Cleavage in 1,2-Oxazetidines: Solvent-Controlled C-H Aminomethylation and Hydroxymethylation of Heteroarenes.

  Org. Lett. 201921, 1602-1606.

16. Cong Wang, Rui-Hua Liu, Ming-Qing Tian, Xu-Hong Hu*, Teck-Peng Loh*. Regioselective Copper-Catalyzed Oxidative Coupling of α-Alkylated Styrenes with Tertiary Alkyl Radicals.

  Org. Lett. 201820, 4032-4035.

15. Jun-Kee Cheng#, Liang Shen#, Liu-Hai Wu, Xu-Hong Hu*, Teck-Peng Loh*. Iron-Catalyzed Peroxidation-Carbamoylation of Alkenes with Hydroperoxides and Formamides via Formyl C(sp2)-H Functionalization.

  Chem. Commun201753, 12830-12833.


Publications before independent career 

14. Xu-Hong Hu, Xiao-Fei Yang, Teck-Peng Loh*. Chelation-assisted rhodium-catalyzed direct amidation with amidobenziodoxolones: C(sp2)-H, C(sp3)-H and late-stage functionalizations. 

   ACS Catal. 20166, 5930-5934.

13. Xu-Hong Hu#, Xiao-Fei Yang#, Teck-Peng Loh*. Selective alkenylation and hydroalkenylation of enol phosphates through direct C-H functionalization. 

   Angew. Chem., Int. Ed. 201554, 15535-15539.

12. Xu-Hong Hu#, Jian Zhang#, Xiao-Fei Yang, Yun-He Xu*, Teck-Peng Loh*.  Stereo- and chemoselective cross-coupling between two electron-deficient acrylates: an efficient route to (Z,E)-muconate derivatives. 

   J. Am. Chem. Soc. 2015137, 3169-3172. (封面文章和亮点介绍)

11. Xu-Hong Hu, Feng Liu, Teck-Peng Loh*. Stereoelectronic verses steric tuning in the Prins cyclization reaction: synthesis of 2,6-trans pyranyl motifs. 

   Org. Lett. 200911, 1741-1743.

10. Xiao-Fei Yang, Xu-Hong Hu, Teck-Peng Loh*. Expedient synthesis of functionalized pyrroloquinolinones by Rh-catalyzed annulation of N-carbamoyl indolines with alkynes through a directed C-H functionalization/C-N cleavage sequence. 

   Org. Lett. 201517, 1481-1484.

9. Xiao-Fei Yang, Xu-Hong Hu, Chao Feng, Teck-Peng Loh*. Rhodium(III)-catalyzed C7-position C-H  alkenylation and alkynylation of indolines. 

   Chem. Commum. 2015, 51, 2532-2535.

8. Ming-Xin Zhang, Xu-Hong Hu, Yun-He Xu*, Teck-Peng Loh*. Selective dealkylation of alkyl ether. 

   Asian J. Org. Chem. 20154, 1047-1049.

7. Han Xu, Xu-Hong Hu, Xiao-Mao Zou, You-Quan Zhu, Bin Liu, Fan-Zhong Hu, Hua-Zheng Yang*. Synthesis and herbicidal activity of 5-heterocycloxy-3-substituted-1-(3-trifluoromethyl)phenyl-1H-pyrazole. 

   Chem. Res. Chin. Univ. 201228, 824-827.

6. Hai-Qing Luo, Xu-Hong Hu, Teck-Peng Loh*. Highly stereocontrolled synthesis of fluorinated 2,6-trans dihydropyrans via Prins cyclization. 

   Tetrahedron Lett. 201051, 1041-1043.

5. Han Xu, Xu-Hong Hu, Bin Liu, You-Quan Zhu, Xiao-Mao Zou, Fan-Zhong Hu, Hua-Zheng Yang*. Synthesis and herbicidal activity of novel 6-methyl-4-(3-trifluoromethylphenyl)pyridazin-3(2H)-one. 

   Chin. J. Org. Chem201030, 1876-1883.

4. Han Xu, Xu-Hong Hu, You-Quan Zhu, Xiao-Mao Zou, Bin Liu, Fan-Zhong Hu, Hua-Zheng Yang*. Synthesis and herbicidal activities of novel 4-(3-trifluoromethylphenyl)-2H-pyridazin-3-one derivatives. 

   Sci. China Chem201053, 157-166.

3. You-Quan Zhu, Xu-Hong Hu, Han Xu, Yong Wang, Xiao-Mao Zou, Hua-Zheng Yang*. Synthesis and QSAR study of novel 8-(3-(trifluoromethyl)phenyl)-6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-ones. 

   Arkivoc 200812, 30-41.

2. Han Xu, Xu-Hong Hu, Xiao-Mao Zou, Bin Liu, You-Quan Zhu, Yong Wang, Fang-Zhong Hu, Hua-Zheng Yang*. Synthesis and herbicidal activities of novel 3-N-substituted amino-6-methyl-4-(3-trifluoromethylphenyl) pyridazine derivatives. 

   J. Agric. Food Chem. 200856, 6567-6572.

1. Han Xu, Xiao-Mao Zou, You-Quan Zhu, Bin Liu, Han-Lin Tao, Xu-Hong Hu, Hai-Bin Song, Fang-Zhong Hu, Yong Wang, Hua-Zheng Yang*, Synthesis and herbicidal activity of novel α,α,α-trifluoro-m-tolyl pyridazinone derivatives. 

   Pest Manag. Sci. 200662, 522-530.