2024年

114. Wanqing Li; Xiaojun Zhang; Jie Ma; Jingyin Zhou; Xuan Di; Donglan Huang; Kaixiang Zhou; Jinming Zhang*; Lu Wang*; Hualong Fu*; Mengchao Cui, Preclinical Evaluation of Dihydropyrazole-Cored Positron Emission Tomography (PET) Ligands for Imaging of Receptor-Interacting Serine/Threonine Protein Kinase 1 (RIPK1) in the Brain, Journal of Medicinal Chemistry, 2024, 67(18): 16403-16415.

113. Wanqing Li; Xiaojun Zhang; Jingyin Zhou; Xuan Di; Donglan Huang; Jie Ma; Kaixiang Zhou; Jinming Zhang*; Lu Wang*; Hualong Fu*; Mengchao Cui, Structure-based discovery of a 4,5-Dihydropyrazole-cored PET ligand for imaging of receptor-interacting serine/threonine-protein kinase 1 (RIPK1) in the brain, European Journal of Medicinal Chemistry, 2024, 279: 116803.

112. Jiaming Guo; Yiling Zhu; Yuqian Qu; Longfei Zhang; Mingxi Fang; Zihan Xu; Tianbao Wang; Yufei Qin; Yihan Xu; Yuying Li; Yimin Chen; Hualong Fu; Xiayu Liu; Yajun Liu; Cheng Liu; Yuan Gao; Mengchao Cui; Kaixiang Zhou*, Structure Tailoring of Hemicyanine Dyes for In Vivo Shortwave Infrared Imaging, Journal of Medicinal Chemistry, 2024, 67(18): 16820-16834.

111. Meiqi Wu; Chao Ren; Chenhui Mao; Liling Dong; Bo Li; Xueqian Yang; Zhenghai Huang; Haiqiong Zhang; Yuying Li; Mengshi Yan; Qi Ge; Runze Wu; Feng Feng; Mengchao Cui; Jing Gao; Li Huo*, Evaluation of a novel PET tracer [18F]-Florbetazine for Alzheimer's disease diagnosis and β-amyloid deposition quantification, NeuroImage, 2024, 298, 120779.

110. Ming Ni; Xingxing Zhu; Kaixuan Wang; Wenliang Guo; Qin Shi; Yuying Li; Mengchao Cui*; Qiang Xie*, Novel β-amyloid PET Imaging Study of [18F]92 in Patients with Cognitive Decline, ACS Omega, 2024, 9(32): 34675-34683.

109. Qi Zeng; Xiaojun Zhang; Yuying Li*; Qilei Zhang; Jiapei Dai; Xiao-xin Yan; Yu Liu; Jinming Zhang*; Sen Liu; Mengchao Cui*, Discovery and Evaluation of Imidazo[2,1-b][1,3,4]thiadiazole Derivatives as New Candidates for α-Synuclein PET Imaging, Journal of Medicinal Chemistry, 2024, 67(15): 12695-12710.

108. Xiaohui Luan; Shaoxi Niu; Yachao Liu; Xiaojun Zhang; Xiaodan Xu; Shuwei Sun; Yabing Sun; Jingfeng Zhang; Yuan Wang; Zhiqiang Chen; Yimin Chen; Mengchao Cui; Ruimin Wang; Xu Zhang*; Jinming Zhang*; Baixuan Xu*. The first-in-human preclinical evaluation of the new probe [123I]I-PSMA-7 for real-time intraoperative targeted biopsy and SPECT/CT imaging in prostate cancer, European Journal of Nuclear Medicine and Molecular Imaging, 2024, DOI: 10.1007/s00259-024-06833-4.

107. Yuying Li; Xiaojun Zhang; Hailong Zhao; Yan Wang; Dandan Zhang; Xiaoming Wang; Ruilin Dong; Xiao-xin Yan; Jing Wu; Yanying Sui; Jinming Zhang*; Mengchao Cui*, Screening of [18F]Florbetazine for Aβ Plaques and a Head-to-Head Comparison Study with [11C]Pittsburgh Compound-B ([11C]PiB) in Human Subjects, ACS Pharmacology & Translational Science, 2024, 7(7): 2054-2062.

106. Cao Lu; Cong Meng; Yuying Li; Jinling Yuan; Xiaojun Ren; Liang Gao; Dongdong Su; Kai Cao; Mengchao Cui; Qing Yuan*; Xueyun Gao*, A probe for NIR-II imaging and multimodal analysis of early Alzheimer’s disease by targeting CTGF, Nature Communications, 2024, 48(3): 166-177.

105. Wantong Guo; Yuying Li; Mengchao Cui*, Research Progress of PET Imaging Agents Targeting Abnormal Protein Aggregates in the Brain, Progress in Pharmaceutical Sciences, 2024, 48(3): 166-177. 

104. Qi-Jie Zhang; Jie Lin; You-Liang Wang; Long Chen; Ying Ding; Fu-Ze Zheng; Huan-Huan Song; Ao-Wei Lv; Yu-Ying Li; Qi-Fu Guo; Min-Ting Lin; Wei Hu; Liu-Qing Xu; Wen-Long Zhao; Ling Fang; Meng-Chao Cui; Zhi-Fei Fu; Wan-Jin Chen; Jing Zhang*; Zhi-Qiang Wang*; Ning Wang*; Ying Fu*, Detection of pTDP-43 via routine muscle biopsy: A promising diagnostic biomarker for amyotrophic lateral sclerosis, Brain Pathology, 2024, e13261.

103. Yuying Li; Tianqing Liu; Qi Zeng; Mengchao Cui*, Current status of PET tracers for the early diagnosis of Alzheimer's disease, TrAC Trends in Analytical Chemistry, 2024, 172(10284):117546.

2023年

102. Longfei Zhang; Xiaojing Shi; Yuying Li; Xiaojiang Duan; Xing Yang; Zhenhua Hu*; Mengchao Cui*, An NIR-II Probe with High PSMA Affinity Demonstrates an Unexpected Excellent Bone Imaging Ability, Journal of Medicinal Chemistry, 2023, 66, 23, 16441–16454.

101.Nan Wu; Longfei Zhang; Xiaojun Zhang; Qilei Zhang; Jiaqi Liu; Yuying Li*; Xiao-xin Yan; Yi Liang; Jinming Zhang*; Mengchao Cui*, Synthesis and Bioevaluation of 2‑Styrylquinoxaline Derivatives as Tau-PET Tracers, Molecular Pharmaceutics, 2023, 20, 11, 5865–5876.


100. Qi Zeng; Sen Liu*; Mengchao Cui*, Structure–Activity Relationships of Cyano-substituted Indole Derivatives as Ligands for α-Synuclein Aggregates, ACS Medicinal Chemistry Letters, 2023, 14, 10, 1467–1471.

99. Yimin Chen; Xiaojun Zhang; Ming Ni; Xi Gao; Xinlin Wang; Qiang Xie*; Jinming Zhang*; Mengchao Cui*, Synthesis, Preclinical Evaluation, and First-in-Human PET Study of [68Ga]-Labeled Biphenyl-Containing PSMA Tracers, Journal of Medicinal Chemistry, 2023, 66, 18, 13332-13345.

98. Yuying Li; Chuan Tian; Tianxin Xie; Qi-Lei Zhang; Jiaqi Liu; Xiao-Xin Yan; Jiapei Dai; Yi Liang*; Mengchao Cui*, Hydroxyethyl-Modified Cycloheptatriene-BODIPY Derivatives as Specific Tau Imaging Probes, ACS Medicinal Chemistry Letters, 2023, 14, 8, 1108-1112.

97. Tianqing Liu; Yuying Li; Xiaojun Zhang; An Yao; Yan Wang; Shulin Yao; Baian Chen*; Xiao-xin Yan; Jiapei Dai; Jinming Zhang*; Mengchao Cui*, Synthesis and Preclinical Evaluation of 2-(4-[18F]Fluorophenyl)imidazo[1,2-h][1,7]naphthyridine ([18F]FPND-4): An Aza-Fused Tricyclic Derivative as Positron Emission Tomography Tracer for Neurofibrillary Tangle Imaging, Journal of Medicinal Chemistry, 2023, 66, 14, 9561-9576.

96. Peizhen Ye; Lei Bi; Min Yang; Yifan Qiu; Guolong Huang; Yongshan Liu; Yuyi Hou; Zhijun Li; Henry Tong; Mengchao Cui; Hongjun Jin*, Activated Microglia in Early Stage of Rat Model of Parkinson's disease (PD): Revealed by PET/MRI Imaging by [18F]DPA-714 Targeting TSPO, ACS Chemical Neuroscience, 2023, 14, 11, 2183-2192.

95. Xinlin Wang; Yimin Chen; Yuqing Xiong; Longfei Zhang; Beibei Wang*; Yajun Liu; Mengchao Cui*, Design and Characterization of Squaramic Acid-Based Prostate-Specific Membrane Antigen Inhibitors for Prostate Cancer, Journal of Medicinal Chemistry, 2023, 66, 10, 6889-6904.

94. Yuying Li; Kaixiang Zhou; Xiaojun Zhang; Hailong Zhao; Xiaoming Wang; Ruilin Dong; Yan Wang; Baian Chen; Xiao-xin Yan; Jiapei Dai; Yanying Sui*; Jinming Zhang*; Mengchao Cui*, Fluorine-18-Labeled Diaryl-azines as Improved β-Amyloid Imaging Tracers: From Bench to First-in-Human Studies, Journal of Medicinal Chemistry, 2023, 66, 7, 4603-4616.

93. Tianqing Liu; Yuying Li; Yan Wang; Xiao-Xin Yan; Jiapei Dai; Mengchao Cui*, Discovery and evaluation of aza-fused tricyclic derivatives for detection of Tau pathology in Alzheimer's disease, European Journal of Medicinal Chemistry, 2023, 246, 114991.

2022年


92. Tianxin Xie; Yuying Li; Chuan Tian; Chang Yuan; Bin Dai; Shubo Wang; Kaixiang Zhou; Jiaqi Liu; Hongwei Tan; Yi Liang*; Jiapei Dai; Baian Chen*; Mengchao Cui*, Fused Cycloheptatriene–BODIPY Is a High-Performance Near-Infrared Probe to Image Tau Tangles, Journal of Medicinal Chemistry, 2022, 65, 21, 14527-14538.

91. Qi Zeng; Yimin Chen; Yingying Yan; Rong Wan; Yanjing Li; Hualong Fu*; Yu Liu; Sen Liu*; Xiao-Xin Yan; Mengchao Cui*, D-π-A-Based Trisubstituted Alkenes as Environmentally Sensitive Fluorescent Probes to Detect Lewy Pathologies, Analytical Chemistry, 2022, 94, 44, 15261-15269.

90. Yimin Chen; Yuying Li; Xi Gao; Mengchao Cui*, Squaraine Dye Based Prostate-Specific Membrane Antigen Probes for Near-Infrared Fluorescence Imaging of Prostate Cancer, Dyes and Pigments, 2022, 208,110822.

89. Nan Yue; Hualong Fu*; Yimin Chen; Xi Gao; Jiapei Dai; Mengchao Cui*, Rational design of molecular rotor-based fluorescent probes with Bi-aromatic rings for efficient in vivo detection of amyloid-β plaques in Alzheimer's disease, European Journal of Medicinal Chemistry, 2022, 243, 114715.

88. Liping Fu*; Jinming Zhang; Kaixiang Zhou; Xiaojun Zhang; Hengge Xie; Mingwei Zhu; Mengchao Cui; Ruimin Wang*, In vivo imaging of tau deposition in Alzheimer’s disease using both [18F]-THK5317 and [18F]-S16: A pilot human study, Frontiers in Aging Neuroscience, 2022, 14, 994750.

87. Xi-Yang Cui; Yu Liu; Changlun Wang; Zihao Wen; Yichen Li; Haocheng Tang; Juan Diwu; Yuchuan Yang; Mengchao Cui; Zhibo Liu*, China’s radiopharmaceuticals on expressway: 2014–2021, Radiochimica Acta, 2022, 110, 6-9.

86. Yuying Li; Tianqing Liu; Mengchao Cui*, Recent development in selective Tau tracers for PET imaging in the brain, Chinese Chemical Letters, 2022, 33, 3339-3348.

85. Jiaying Zhang; Zefang Lin; Xiaojun Zhang; Rong Lin; Mengchao Cui; Weibing Miao; Shaobo Yao*, 68Ga-DOTA-DiPSMA PET/CT Imaging: Biodistribution, Dosimetry, and Preliminary Application in Prostate Cancer, Frontiers in Bioengineering and Biotechnology, 2022, 9, 811972.

84. Ying Wang; Li Cai; Kaixiang Zhou; Mengchao Cui; Shaobo Yao*, Biodistribution and Dosimetry Evaluation for a Novel Tau Tracer [18F]-S16 in Healthy Volunteers and Its Application in Assessment of Tau Pathology in Alzheimer’s Disease, Frontiers in Bioengineering and Biotechnology, 2022, 9, 812818.

83. Wei Dong; Meng-chao Cui; Wen-Zheng Hu; Qi Zeng; Yi-Long Wang; Wei Zhang; Yue Huang*, Genetic and Molecular Evaluation of SQSTM1/p62 on the Neuropathologies of Alzheimer's Disease, Frontiers in Aging Neuroscience, 2022, 14, 829232.

82. Qi Zeng; Mengchao Cui*, Current Progress in the Development of Probes for Targeting α-Synuclein Aggregates, ACS Chemical Neuroscience, 2022, 2022,13, 552−571.

81. Ying Zhang; Tao Wang; Xiaojun Zhang; Winnie Deuther-Conrad; Hualong Fu; Mengchao Cui; Jinming Zhang*; Peter Brust; Yiyun Huang*; Hongme Jia*, Discovery and development of brain-penetrant 18F-labeled radioligands for neuroimaging of the sigma-2 receptors, Acta Pharmaceutica Sinica B, 2022, 12, 1406-1415.

80. Yimin Chen; Qingwen Ouyang; Yuying Li; Qi Zeng; Bin Dai; Yi Liang; Baian Chen∗; Hongwei Tan; Mengchao Cui*, Evaluation of N, O-Benzamide difluoroboron derivatives as near-infrared fluorescent probes to detect β-amyloid and tau tangles, European Journal of Medicinal Chemistry, 2022, 227,113968.

2021年


79. Xu Zhou; Lin-Lin Dong; Yuying Li; Meng-chao Cui*; Lang-Tao Shen*, Design and synthesis of a new conjugate of a tris(3-hydroxy-4-pyridinone) chelator (KC18) for potential use as gallium-68-labeled prostate-specific membrane antigen (PSMA) radiopharmaceutical, Results in Chemistry, 2021, 3, 100240.


78. Ahmed A. Elbatrawy; Seung Jae Hyeon; Nan Yue; Essam Eldin A. Osman; Seung Hyeo Choi; Sungsu Lim; Yun Kyung Kim; Hoon Ryu; Mengchao Cui; Ghilsoo Nam*, “Turn-On” Quinoline-Based Fluorescent Probe for Selective Imaging of Tau Aggregates in Alzheimer’s Disease: Rational Design, Synthesis, and Molecular Docking, ACS Sensors, 2021, 6, 6, 2281-2289.


77. Longfei Zhang; Xiaojing Shi; Yuying Li; Xiaojiang Duan; Zeyu Zhang; Hualong Fu; Xing Yang; Jie Tian; Zhenhua Hu*; Mengchao Cui*, Visualizing Tumors in Real Time: A Highly Sensitive PSMA Probe for NIR-II Imaging and Intraoperative Tumor Resection, Journal of Medicinal Chemistry, 2021, 64, 11, 7735-7745.

‍76. Xiaojun Zhang; Yitian Wu; Qi Zeng; Tianxin Xie; Shulin Yao*; Jinming Zhang*; Mengchao Cui*, Synthesis, Preclinical Evaluation, and First-in-Human PET Study of Quinoline-Containing PSMA Tracers with Decreased Renal Excretion, Journal of Medicinal Chemistry, 2021, 64, 7, 4179-4195.‍

75. Kaixiang Zhou; Fan Yang; Yuying Li; Yimin Chen; Xiaojun Zhang; Jinming Zhang; Junfeng Wang; Jiapei Dai; Lisheng Cai*; Cui, Mengchao*, Synthesis and Evaluation of Fluorine-18 Labeled 2-Phenylquinoxaline Derivatives as Potential Tau Imaging Agents, Molecular Pharmaceutics, 2021, 18, 1176-1195.


74. Longfei Zhang; Xin Gong; Chuan Tian; Hualong Fu*; Hongwei Tan; Jiapei Dai; Cui, Mengchao*, Near-Infrared Fluorescent Probes with Rotatable Polyacetylene Chains for the Detection of Amyloid-β Plaques, Journal of Physical Chemistry B, 2021, 125, 497.

73. Yuying Li; Kaixiang Zhou; Wentao Guo; Cui, Mengchao*, 18F-labeled 2-phenylbenzoheterocycles with chiral dihydroxyl side chains as β-amyloid imaging probes, Bioorganic & Medicinal Chemistry, 2021, 29, 115884.

72. He, Yujia; Fu, Tingting; Li, Yuying; Xue, Weiwei; Cui, Mengchao; Wang, Liang; Niu, Mengda; Peng, Zhiping; Jia, Jianhua, Flexible multidentate benzyldiamine derivatives with high affinity for β-amyloid in cerebral amyloid angiopathy, Molecular Diversity, 2021, 25, 525–533.

2020年


71. Jia, Jianhua; Zhang, Longfei; Song, Jia; Dai, Jiapei; Cui, Mengchao*, Discovery of Diphenoxy Derivatives with Flexible Linkers as Ligands for β-amyloid Plaques, Molecular Pharmaceutics, 2020, 17, 4089−4100.

70. Liu, Huiyu; Zhang, Siqi; Cui, Mengchao; Gao, Lihua; Zhao, Hua; Wang, Kezhi*, A pH-Sensitive Near-IR Emitting Dinuclear Ruthenium Complex for Recognization, Two-Photon Luminescent Imaging and Subcellular Localization of Cancer Cells, ACS Applied Bio Materials, 2020, 3, 8, 5420–5427.

69. Chen, Yimin; Yuan, Chang; Xie, Tianxin; Li, Yuying; Dai, Bin; Zhou, Kaixiang; Liang, Yi; Dai, Jiapei; Tan, Hongwei*; Cui, Mengchao*, N,O-Benzamide Difluoroboron Complexes as Near-infrared Probes for the Detection of β-amyloid and Tau Fibrils, Chemical Communications, 2020, 56, 7269-7272.

2019年


68. Li, Yuying; Cui, Mengchao*, Progress of Near-Infrared Fluorescent Probes for β-Amyloid Plaques in the Brain, Chinese Journal of Analytical Chemistry, 2019, 47(10): 1524-1536.

67. Tan, Huiya; Zhou, Kaixiang; Yan, Jinwu*; Sun, Han; Pistolozzi, Marco; Cui, Mengchao*; Zhang, Lei*, Dual-functional red-emitting fluorescent probes for imaging beta-amyloid plaques and viscosity, Sensors and Actuators B: Chemical, 2019, 298, 126903.

66. Zhou, Kaixiang; Yuan, Chang; Dai, Bin; Wang, Kan; Chen, Yimin; Ma, Denglei; Dai, Jiapei; Liang, Yi*; Tan, Hongwei*; Cui, Mengchao*, Environment-Sensitive Based Near-Infrared Probe for Fluorescent Discrimination of Aβ and Tau Fibrils in AD Brain, Journal of Medicinal Chemistry, 2019, 62, 14, 6694-6704.

65. Yang, Fan; Wang, Kan; Zhou, Kaixiang; Dai, Bin; Dai, Jiapei; Liang, Yi*; Cui, Mengchao*, Synthesis and bioevaluation of technetium-99 m / rhenium labeled phenylquinoxaline derivatives as Tau imaging probes, European Journal of Medicinal Chemistry, 2019, 177: 291-301.


64. Yang, Jian; Cheng, Ran; Fu, Hualong; Yang, Jing; Kumar, Mohanraja; Lu, Jie; Xu, Yungen; Liang, Steven H; Cui, Mengchao*; Ran Chongzhao*, Half-curcumin analogues as PET imaging probes for Amyloid beta species, Chemical Communications, 2019, 55, 3630-3633.


2018年


63. Song, Jia; Peng, Xiaohui; Li, Linlin; Yang, Fan; Zhang, Xiaojun; Zhang, Jinming*; Dai, Jiapei; Cui, Mengchao*, Al¹⁸F‑NODA Benzothiazole Derivatives as Imaging Agents for Cerebrovascular Amyloid in Cerebral Amyloid Angiopathy, ACS Omega, 2018, 3, 13089−13096.

62. Zhou, Kaixiang; Li, Yuying; Peng, Yi; Cui, Xiaomei; Dai, Jiapei; Cui, Mengchao*, Structure−Property Relationships of Polyethylene Glycol Modified Fluorophore as Near-Infrared Aβ Imaging Probes, Analytical Chemistry, 2018, 90, 8576−8582.

61. Li, Yuying; Wang, Kan; Zhou, Kaixiang; Guo, Wentao; Dai, Bin; Liang, Yi*; Dai, Jiapei; Cui, Mengchao*, Novel D-A-D based near-infrared probes for the detection of b-amyloid and Tau fibrils in Alzheimer’ s disease, Chemical Communications, 2018, 54, 8717-8720.

60. Fu, Hualong; Cui, Mengchao*, Fluorescent Imaging of Amyloid-β Deposits in Brain: An Overview of Probe Development and a Highlight of the Applications for In Vivo Imaging, Current Medicinal Chemistry, 2018, 25, 2736-2759.

59. Zhang, Xiaoyang; Hou, Yaqin; Peng, Cheng; Wang, Chu; Wang, Xiang; Liang, Zhigang*; Lu, Jing; Chen, Baian*; Dai, Jiapei; Liu, Boli; Cui, Mengchao*, Oligoethyleneoxy-Modified 99mTc-Labeled β‑Amyloid Imaging Probes with Improved Brain Pharmacokinetics for Single-Photon Emission Computed Tomography, Journal of Medicinal Chemistry, 2018, 61(3): 1330-1339.

2017年

58. Yan, Jin-wu; Zhu, Jia-ying; Zhou, Kai-xiang; Wang, Jin-sheng; Tan, Hui-ya; Xu, Zhong-yong; Chen, Shuo-bin; Lu, Yu-ting; Cui, Meng-chao*; Zhang, Lei*, Neutral merocyanine dyes: for in vivo NIR fluorescence imaging of amyloid-beta plaques, Chemical Communications, 2017, 53(71): 9910-9913.

57. Zhou, Kaixiang; Bai, Hongcun; Feng, Liang; Dai, Jiapei; Cui, Mengchao*, Smart D-pi-A Type Near-Infrared Aβ Probes: Effects of a Marked pi Bridge on Optical and Biological Properties, Analytical Chemistry, 2017, 89(17): 9432-9437.

56. Wang, Liang; Ye, Jiajun; He, Yingfang; Deuther-Conrad, Winnie; Zhang, Jinming; Zhang, Xiaojun; Cui, Mengchao*; Steinbach, Joerg; Huang, Yiyun; Brust, Peter; Jia, Hongmei*, F-18-Labeled indole-based analogs as highly selective radioligands for imaging sigma-2 receptors in the brain, Bioorganic & Medicinal Chemistry, 2017, 25(14): 3792-3802.

55. Jia Song; Xiaoyang Zhang; Yunling Zhao; Hui Yang; Jinming Zhang*; Xiaojun Zhang; Jiapei Dai; Mengchao Cui*, (R)- and (S)-18F-labeled 2-arylbenzofurans with improved pharmacokinetics as β-amyloid imaging probes, European Journal of Medicinal Chemistry, 2017, 134: 271-280.

54. Chen, Kaihua; Cui, Mengchao*, Recent progress in the development of metal complexes as β-amyloid imaging probes in the brain, Medchemcomm, 2017, 8(7): 1393-1407.

53. Liu, Yajing; Yang, Yanping; Sun, Mingjian; Cui, Mengchao; Fu, Ying; Lin, Yu; Li, Zijing*; Nie, Liming*, Highly specific noninvasive photoacoustic and positron emission tomography of brain plaque with functionalized croconium dye labeled by a radiotracer, Chemical Science, 2017, 8(4): 2710-2716.

52. Li, Lingjun*; Ding, Shengqiang; Yang, Yanping; Zhu, Anlian; Fan, Xincui; Cui, Mengchao*; Chen, Changpo; Zhang, Guisheng*, Multicomponent Aqueous Synthesis of Iodo-1,2,3-triazoles: Single-Step Models for Dual Modification of Free Peptide and Radioactive Iodo Labeling, Chemistry - A European Journal, 2017, 23(5): 1166-1172.

2016年

51.  Li, Zijing*; Zhang, Xuran; Zhang, Xiaoyang; Cui, Mengchao; Lu, Jie; Pan, Xiaodong*; Zhang, Xianzhong*, F-18-Labeled Benzyldiamine Derivatives as Novel Flexible Probes for Positron Emission Tomography of Cerebral β-Amyloid Plaques, Journal of Medicinal Chemistry, 2016, 59(23): 10577-10585.

50.  Jia, Jianhua; Zhou, Kaixiang; Dai, Jiapei; Liu, Soli; Cui, Mengchao*, 2-Arylbenzothiazoles labeled with [CpRe/Tc-99m(CO)(3)] and evaluated as β-amyloid imaging probes, European Journal of Medicinal Chemistry, 2016, 124: 763-772.

49.  Yang, Yanping; Wang, Xuedan; Yang, Hui; Fu, Hualong; Zhang, Jinming; Zhang, Xiaojun; Dai, Jiapei; Zhang, Zhiyong; Lin, Chunping; Guo, Yuzhi; Cui, Mengchao*, Synthesis and Monkey-PET Study of (R)- and (S)-F-18-Labeled 2-Arylbenzoheterocyclic Derivatives as Amyloid Probes with Distinctive in Vivo Kinetics, Molecular Pharmaceutics, 2016, 13(11): 3852-3863.

48.  Zhang, Xiaoyang; Yu, Pingrong; Yang, Yanping; Hou, Yaqin; Peng, Cheng; Liang, Zhigang*; Lu, Jing; Chen, Baian*; Dai, Jiapei; Liu, Boli; Cui, Mengchao*, Tc-99m-Labeled 2-Arylbenzothiazoles: Aβ Imaging Probes with Favorable Brain Pharmacokinetics for Single-Photon Emission Computed Tomography, Bioconjugate Chemistry, 2016, 27(10): 2493-2504.

47.  Jia, Jianhua; Song, Jia; Dai, Jiapei; Liu, Boli; Cui, Mengchao*, Optically Pure Diphenoxy Derivatives as More Flexible Probes for β-Amyloid Plaques, ACS Chemical Neuroscience, 2016, 7(9): 1275-1282.

46.  Ren, Hong; Long, Zi; Cui, Mengchao; Shao, Kang; Zhou, Kaixiang; Ouyang, Jin; Na, Na*, Dual-Functional Nanoparticles for In Situ Sequential Detection and Imaging of ATP and H₂O₂, Small, 2016, 12(29): 3920-3924.

45.  Fu, Hualong; Tu, Peiyu; Zhao, Liu; Dai, Jiapei; Liu, Boli; Cui, Mengchao*, Amyloid-beta Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation, and in Vivo Imaging, Analytical Chemistry, 2016, 88(3): 1944-1950.

44.  Fu, Hualong; Peng, Cheng; Liang, Zhigang; Dai, Jiapei; Liu, Boli; Cui, Mengchao*, In vivo near-infrared and Cerenkov luminescence imaging of amyloid-beta deposits in the brain: a fluorinated small molecule used for dual-modality imaging, Chemical Communications, 2016, 52(86): 12745-12748.

43.  Cui, Xiaomei; Zhang, Xiaoyang; Peng, Cheng; Dai, Jiapei; Liu, Boli; Cui, Mengchao*, Radiolabeled pyridinyl analogues of dibenzylideneacetone as β-amyloid imaging probes, RSC Advances, 2016, 6(50): 44646-44654.

2015年

42.  Yang, Yanping; Fu, Hualong; Cui, Mengchao*; Peng, Cheng; Liang, Zhigang*; Dai, Jiapei; Zhang, Zhiyong; Lin, Chunping; Liu, Boli, Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of β-amyloid plaques by positron emission tomography, European Journal of Medicinal Chemistry, 2015, 104: 86-96.

41.  Fu, Hualong; Cui, Mengchao*; Zhao, Liu; Tu, Peiyu; Zhou, Kaixiang; Dai, Jiapei; Liu, Boli, Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid-beta Plaques in Alzheimer's Disease, Journal of Medicinal Chemistry, 2015, 58(17): 6972-6983.

40.  Jia, Jianhua; Cui, Mengchao*; Dai, Jiapei; Liu, Boli, Tc-99m(CO)(3)-Labeled Benzothiazole Derivatives Preferentially Bind Cerebrovascular Amyloid: Potential Use as Imaging Agents for Cerebral Amyloid Angiopathy, Molecular Pharmaceutics, 2015, 12(8): 2937-2946.

39.  Yang, Yanping; Zhang, Xiaoyang; Cui, Mengchao*; Zhang, Jinming*; Guo, Zhide; Li, Yesen; Zhang, Xianzhong; Dai, Jiapei; Liu, Boli, Preliminary Characterization and In Vivo Studies of Structurally Identical F-18- and I-125-Labeled Benzyloxybenzenes for PET/SPECT Imaging of β-Amyloid Plaques, Scientific Reports, 2015, 5: 12084.

38.  Tu, Peiyu; Fu, Hualong; Cui, Mengchao*, Compounds for imaging amyloid-beta deposits in an Alzheimer's brain: a patent review, Expert Opinion on Therapeutic Patents, 2015, 25(4): 413-423.

37.  Wang, Xuedan; Cui, Mengchao*; Jia, Jianhua; Liu, Boli, Tc-99m-labeled-2-arylbenzoxazole derivatives as potential Aβ imaging probes for single-photon emission computed tomography, European Journal of Medicinal Chemistry, 2015, 89: 331-339.

36.  Zhou, Kaixiang; Fu, Hualong; Feng, Liang; Cui, Mengchao*; Dai, Jiapei; Liu, Boli, The synthesis and evaluation of near-infrared probes with barbituric acid acceptors for in vivo detection of amyloid plaques, Chemical Communications, 2015, 51(58): 11665-11668.

35.  Jia, Jianhua; Cui, Mengchao*; Dai, Jiapei; Liu, Boli, 2-Phenylbenzothiazole conjugated with cyclopentadienyl tricarbonyl [CpM(CO)(3)] (M = Re, Tc-99m) complexes as potential imaging probes for β-amyloid plaques, Dalton Transactions, 2015, 44(14): 6406-6415.

2014年

34.  Yang, Yanping; Cui, Mengchao*, Radiolabeled bioactive benzoheterocycles for imaging β-amyloid plaques in Alzheimer's disease, European Journal of Medicinal Chemistry, 2014, 87: 703-721.

33.  Li, Zijing; Cui, Mengchao*; Zhang, Jinming*; Dai, Jiapei; Zhang, Xiaojun; Chen, Peng; Jia, Hongmei; Liu, Boli, Novel F-18-labeled dibenzylideneacetone derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques, European Journal of Medicinal Chemistry, 2014, 84: 628-638.

32.  Wang, Xia; Li, Dan; Deuther-Conrad, Winnie; Lu, Jie; Xie, Ying; Jia, Bing; Cui, Mengchao; Steinbach, Joerg; Brust, Peter; Liu, Boli; Jia, Hongmei*, Novel Cyclopentadienyl Tricarbonyl Tc-99m Complexes Containing 1-Piperonylpiperazine Moiety: Potential Imaging Probes for Sigma-1 Receptors, Journal of Medicinal Chemistry, 2014, 57(16): 7113-7125.

31.  Yang, Yanping; Cui, Mengchao*; Zhang, Xiaoyang; Dai, Jiapei; Zhang, Zhiyong; Lin, Chunping; Guo, Yuzhi; Liu, Boli, Radioiodinated Benzyloxybenzene Derivatives: A Class of Flexible Ligands Target to β-Amyloid Plaques in Alzheimer's Brains, Journal of Medicinal Chemistry, 2014, 57(14): 6030-6042.

30.  Cui, Mengchao; Ono, Masahiro*; Watanabe, Hiroyuki; Kimura, Hiroyuki; Liu, Boli; Saji, Hideo, Smart Near-Infrared Fluorescence Probes with Donor-Acceptor Structure for in Vivo Detection of β-Amyloid Deposits, Journal of the American Chemical Society, 2014, 136(9): 3388-3394.

29.  Cui, Mengchao; Tang, Ruikun; Zhang, Jinming; Zhang, Xiaojun; Li, Zijing; Jia, Hongmei; Liu, Boli*, Carbon-11 labeled stilbene derivatives from natural products for the imaging of Aβ plaques in the brain, Radiochimica Acta, 2014, 102(1-2): 185-192.

28.  Fu, Hualong; Cui, Mengchao*; Tu, Peiyu; Pan, Ziwei; Liu, Boli, Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes, Chemical Communications, 2014, 50(80): 11875-11878.

27.  Chen, Yuan-Yuan; Wang, Xia; Zhang, Jin-Ming; Deuther-Conrad, Winnie; Zhang, Xiao-Jun; Huang, Yiyun; Li, Yan; Ye, Jia-Jun; Cui, Meng-Chao; Steinbach, Joerg; Brust, Peter; Liu, Bo-Li; Jia, Hong-Mei*, Synthesis and evaluation of a F-18-labeled spirocyclic piperidine derivative as promising sigma(1) receptor imaging agent, Bioorganic & Medicinal Chemistry, 2014, 22(19): 5270-5278.

26.  Jia, Jianhua; Cui, Mengchao*; Dai, Jiapei; Wang, Xuedan; Ding, Yu-Shin; Jia, Hongmei; Liu, Boli, Tc-99m-labeled benzothiazole and stilbene derivatives as imaging agents for Aβ plaques in cerebral amyloid angiopathy, Medchemcomm, 2014, 5(2): 153-158.

25.  Cui, Mengchao*, Past and Recent Progress of Molecular Imaging Probes for β-Amyloid Plaques in the Brain, Current Medicinal Chemistry, 2014, 21(1): 82-112.

2013年

24.  Yoshimura, Masashi; Ono, Masahiro; Matsumura, Kenji; Watanabe, Hiroyuki; Kimura, Hiroyuki; Cui, Mengchao; Nakamoto, Yuji; Togashi, Kaori; Okamoto, Yoko; Ihara, Masafumi; Takahashi, Ryosuke; Saji, Hideo, Structure–Activity Relationships and in Vivo Evaluation of Quinoxaline Derivatives for PET Imaging of β-Amyloid Plaques, ACS Medicinal Chemistry Letters, 2013, 4(7): 596-600.

23.  Fu, Hualong; Yu, Lihai; Cui, Mengchao*; Zhang, Jinming; Zhang, Xiaojun; Li, Zijing; Wang, Xuedan; Jia, Jianhua; Yang, Yanping; Yu, Pingrong; Jia, Hongmei; Liu, Boli*, Synthesis and biological evaluation of F-18-labled 2-phenylindole derivatives as PET imaging probes for β-amyloid plaques, Bioorganic & Medicinal Chemistry, 2013, 21(13): 3708-3714.

22.  Wang, Xia; Li, Yan; Deuther-Conrad, Winnie; Xie, Fang; Chen, Xin; Cui, Meng-Chao; Zhang, Xiao-Jun; Zhang, Jin-Ming; Steinbach, Joerg; Brust, Peter; Liu, Bo-Li; Jia, Hong-Mei*, Synthesis and biological evaluation of F-18 labeled fluoro-oligo-ethoxylated 4-benzylpiperazine derivatives for sigma-1 receptor imaging, Bioorganic & Medicinal Chemistry, 2013, 21(1): 215-222.

21.  Yang, Yanping; Cui, Mengchao*; Jin, Bing; Wang, Xuedan; Li, Zijing; Yu, Pingrong; Jia, Jianhua; Fu, Hualong; Jia, Hongmei; Liu, Boli*, Tc-99m-labeled dibenzylideneacetone derivatives as potential SPECT probes for in vivo imaging of β-amyloid plaque, European Journal of Medicinal Chemistry, 2013, 64: 90-98.

20.  Li, Yan; Wang, Xia; Zhang, Jinming; Deuther-Conrad, Winnie; Xie, Fang; Zhang, Xiaojun; Liu, Jian; Qiao, Jinping; Cui, Mengchao; Steinbach, Jorg; Brust, Peter; Liu, Boli; Jia, Hongmei*, Synthesis and Evaluation of Novel F-18-Labeled Spirocyclic Piperidine Derivatives as sigma(1) Receptor Ligands for Positron Emission Tomography Imaging, Journal of Medicinal Chemistry, 2013, 56(9): 3478-3491.

19.  Li, Zijing; Cui, Mengchao*; Dai, Jiapei; Wang, Xuedan; Yu, Pingrong; Yang, Yanping; Jia, Jianhua; Fu, Hualong; Ono, Masahiro; Jia, Hongmei; Saji, Hideo; Liu, Boli*, Novel Cyclopentadienyl Tricarbonyl Complexes of Tc-99m Mimicking Chalcone as Potential Single-Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Brain, Journal of Medicinal Chemistry, 2013, 56(2): 471-482.

2012年

18.  Cui, Mengchao; Ono, Masahiro*; Kimura, Hiroyuki; Ueda, Masashi; Nakamoto, Yuji; Togashi, Kaori; Okamoto, Yoko; Ihara, Masafumi; Takahashi, Ryosuke; Liu, Boli; Saji, Hideo, Novel F-18-Labeled Benzoxazole Derivatives as Potential Positron Emission Tomography Probes for Imaging of Cerebral β-Amyloid Plaques in Alzheimer's Disease, Journal of Medicinal Chemistry, 2012, 55(21): 9136-9145.

17.  Cui, Mengchao*; Wang, Xuedan; Yu, Pingrong; Zhang, Jinming; Li, Zijing; Zhang, Xiaojun; Yang, Yanping; Ono, Masahiro; Jia, Hongmei; Saji, Hideo; Liu, Boli*, Synthesis and Evaluation of Novel F-18 Labeled 2-Pyridinylbenzoxazole and 2-Pyridinylbenzothiazole Derivatives as Ligands for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques, Journal of Medicinal Chemistry, 2012, 55(21): 9283-9296.

16.  Yu, Pingrong; Cui, Mengchao*; Wang, Xuedan; Zhang, Xiaojun; Li, Zijing; Yang, Yanping; Jia, Jianhua; Zhang, Jinming; Ono, Masahiro; Saji, Hideo; Jia, Hongmei; Liu, Boli*, F-18-Labeled 2-phenylquinoxaline derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques, European Journal of Medicinal Chemistry, 2012, 57: 51-58.

15.  Wang, Xuedan; Cui, Mengchao*; Yu, Pingrong; Li, Zijing; Yang, Yanping; Jia, Hongmei; Liu, Boli*, Synthesis and biological evaluation of novel technetium-99m labeled phenylbenzoxazole derivatives as potential imaging probes for β-amyloid plaques in brain, Bioorganic & Medicinal Chemistry Letters, 2012, 22(13): 4327-4331.

14.  Chen, Xin; Cui, Meng-Chao; Deuther-Conrad, Winnie; Tu, Ying-Feng; Ma, Teng; Xie, Ying; Jia, Bing; Li, Yan; Xie, Fang; Wang, Xia; Steinbach, Joerg; Brust, Peter; Liu, Bo-Li; Jia, Hong-Mei*, Synthesis and biological evaluation of a novel Tc-99m cyclopentadienyl tricarbonyl complex ([(Cp-R)Tc-99m(CO)(3)]) for sigma-2 receptor tumor imaging, Bioorganic & Medicinal Chemistry Letters, 2012, 22(20): 6352-6357.

2011年

13.  Cui, Mengchao; Ono, Masahiro*; Kimura, Hiroyuki; Liu, Boli; Saji, Hideo*, Novel quinoxaline derivatives for in vivo imaging of β-amyloid plaques in the brain, Bioorganic & Medicinal Chemistry Letters, 2011, 21(14): 4193-4196.

12.  Cui, Mengchao; Ono, Masahiro*; Kimura, Hiroyuki; Liu, Boli; Saji, Hideo*, Synthesis and evaluation of benzofuran-2-yl(phenyl)methanone derivatives as ligands for β-amyloid plaques, Bioorganic & Medicinal Chemistry, 2011, 19(13): 4148-4153.

11.  Cui, Mengchao; Li, Zijing; Tang, Ruikun; Jia, Hongmei*; Liu, Boli*, Novel (E)-5-styryl-2,2 '-bithiophene derivatives as ligands for β-amyloid plaques, European Journal of Medicinal Chemistry, 2011, 46(7): 2908-2916.

10.  Ono, Masahiro*; Cheng, Yan; Kimura, Hiroyuki; Cui, Mengchao; Kagawa, Shinya; Nishii, Ryuichi; Saji, Hideo*, Novel 18 F-Labeled Benzofuran Derivatives with Improved Properties for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques in Alzheimer’s Brains, Journal of Medicinal Chemistry, 2011, 54(8): 2971-2979.

9.  Cui, Mengchao; Ono, Masahiro*; Kimura, Hiroyuki; Liu, Boli; Saji, Hideo*, Synthesis and Structure-Affinity Relationships of Novel Dibenzylideneacetone Derivatives as Probes for β-Amyloid Plaques, Journal of Medicinal Chemistry, 2011, 54(7): 2225-2240.

8.  Cui, Mengchao; Ono, Masahiro*; Kimura, Hiroyuki; Kawashima, Hidekazu; Liu, Bo Li; Saji, Hideo*, Radioiodinated benzimidazole derivatives as single photon emission computed tomography probes for imaging of β-amyloid plaques in Alzheimer's disease, Nuclear Medicine and Biology, 2011, 38(3): 313-320.

7.  Cui, Mengchao; Ono, Masahiro; Kimura, Hiroyuki; Liu, Bo Li; Saji, Hideo, Synthesis and biological evaluation of indole-chalcone derivatives as β-amyloid imaging probe, Bioorganic & Medicinal Chemistry Letters, 2011, 21(3): 980-982.

6.  Cui, Mengchao; Tang, Ruikun; Li, Zijing; Ren, Huiying; Liu, Boli*, Tc-99m- and Re-labeled 6-dialkylamino-2-naphthylethylidene derivatives as imaging probes for β-amyloid plaques, Bioorganic & Medicinal Chemistry Letters, 2011, 21(3): 1064-1068.

5.  Li, Zi-Jing; Ren, Hui-Ying; Cui, Meng-Chao; Deuther-Conrad, Winnie; Tang, Rui-Kun; Steinbach, Joerg; Brust, Peter; Liu, Bo-Li; Jia, Hong-Mei*, Synthesis and biological evaluation of novel 4-benzylpiperazine ligands for sigma-1 receptor imaging, Bioorganic & Medicinal Chemistry, 2011, 19(9): 2911-2917.

2010年

4.  Yang, Yang; Zhu, Lin; Cui, Mengchao; Tang, Ruikun; Zhang, Huabei*, Preparation of classical Re/Tc-99m(CO)(3)(+) and novel Tc-99m(CO)(2)(NO)(2+) cores complexed with flavonol derivatives and their binding characteristics for Aβ((1-40)) aggregates, Bioorganic & Medicinal Chemistry Letters, 2010, 20(17): 5337-5344.

3.  Cui, Meng-Chao; Li, Zi-Jing; Tang, Rui-Kun; Liu, Bo-Li*, Synthesis and evaluation of novel benzothiazole derivatives based on the bithiophene structure as potential radiotracers for β-amyloid plaques in Alzheimer's disease, Bioorganic & Medicinal Chemistry, 2010, 18(7): 2777-2784.

2.  Ono, Masahiro*; Ishikawa, Manami; Kimura, Hiroyuki; Hayashi, Shun; Matsumura, Kenji; Watanabe, Hiroyuki; Shimizu, Yoichi; Cheng, Yan; Cui, Mengchao; Kawashima, Hidekazu; Saji, Hideo*, Development of dual functional SPECT/fluorescent probes for imaging cerebral β-amyloid plaques, Bioorganic & Medicinal Chemistry Letters, 2010, 20(13): 3885-3888.

1.  Duan, Xin-Hong; Qiao, Jin-Ping; Yang, Yang; Cui, Meng-Chao; Zhou, Jiang-Ning; Liu, Bo-Li*, Novel anilinophthalimide derivatives as potential probes for β-amyloid plaque in the brain, Bioorganic & Medicinal Chemistry, 2010, 18(3): 1337-1343.