汪卫平 - 香港大学 - Laboratory of Molecular Engineering and Nanomedicine

研究领域

Currently, the key research areas in the group are (i) photopharmacology & photomedicine; (ii) ocular drug delivery; (iii) engineering stimuli-responsive nanomaterials for drug delivery; (iv) engineering genetic systems (CRISPR/Cas9) in stem cells or for disease treatment; and (v) regulating autophagy for cancer therapy or Alzheimer’s treatment.

近期论文

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Kaiqi Long1, Han Han1, Weirong Kang, Wen Lv, Lang Wang, Yufeng Wang, Liang Ge*, Weiping Wang*, One-photon Red Light-triggered Disassembly of Small-molecule Nanoparticles for Drug Delivery, 2021, Submitted Kang Chen, Yuan Gao, Yaming Zhang, Tianshi Feng, Qin Wang, Leigang Jin, Eric Honoré, Karen S L Lam, Weiping Wang*, Xiaoyan Hui,*, Aimin Xu,* , Adipose-Targeted Triiodothyronine Therapy Counteracts Obesity-Related Metabolic Complications and Atherosclerosis with Negligible Side Effects, 2021, Submitted Tianyi Wang, Kaiqi Long, Yang Zhou, Xiaoding Jiang, Jinzhao Liu, John H.C. Fong, Alan S.L. Wong, Wai-Lung Ng, Weiping Wang*, Optochemical Control of mTOR Signaling and mTOR-dependent Autophagy, 2021, Submitted Kaiqi Long1, Yifan Wang1, Wen Lv, Yang Yang, Shuting Xu, Changyou Zhan, Weiping Wang*, Photoresponsive Prodrug Nanoparticles Co-assembled with IR783 for Cancer Therapy, 2021, Submitted Yafei Li1, Yang Zhou1, Kaiqi Long, Yaming Zhang, Tianyi Wang, Weiping Wang*, Photoenhanced cytosolic protein delivery based on a photocleavable group-modified dendrimer, 2021, Nanoscale, In revision Tongtong Zhang, Linjie Ma, Lingzhi Wang, Feng Xu, Qiang Wei, Weiping Wang, Yuan Lin, Zhiqin Chu*, Scalable Fabrication of Clean Nanodiamonds via Salt-Assisted Air Oxidation: Implications Toward Sensing and Imaging, 2021, ACS Applied Nano Materials, DOI: 10.1021/acsanm.1c01751 Kaiqi Long1, Yang Yang1, Wen Lv, Kuan Jiang, Yafei Li, Amy Cheuk Yin Lo, Wai Ching Lam, Changyou Zhan*, Weiping Wang*, Green light-triggered intraocular drug release for intravenous chemotherapy of retinoblastoma, Advanced Science, 2021, 2101754 Manman Jing1, Yafei Li1, Meimei Wang, Hao Zhang, Pengfei Wei, Yang Zhou, Nestor Ishimwe, Xiaowan Huang, Liansheng Wang, Longping Wen*, Weiping Wang*, Yunjiao Zhang*, Photoresponsive PAMAM-assembled nanocarrier loaded with autophagy inhibitor for synergistic cancer therapy, Small, 2021, 2102295. Yafei Li, Wen Lv, Lang Wang, Yaming Zhang, Lipeng Yang, Tianyi Wang, Linyong Zhu, Yufeng Wang, Weiping Wang*, Photo-triggered nucleus targeting for cancer drug delivery, Nano Research, 2021, 14, 2630–2636 Huan Wang, Tianhao Ding, Juan Guan, Xia Liu, Jing Wang, Pengpeng Jin, Shuangxing Hou, Weiyue Lu, Jun Qian, Weiping Wang and Changyou Zhan*, Interrogation of folic acid functionalized nanomedicines: the regulatory roles of plasma proteins reexamined, ACS Nano, 2020, 14, 14779–14789 Wen Lv, Kaiqi Long, Yang Yang, Sijie Chen, Changyou Zhan and Weiping Wang*, A Red Light-Triggered Drug Release System Based on One-Photon Upconversion-Like Photolysis, Advanced Healthcare Materials, 2020, 2001118 Fang Wang, Rengan Luo, Hao Xin, Yaming Zhang, Bernardino J. Córdova Wong, Weiping Wang* and Jianping Lei*, Hypoxia-stimulated tumor therapy associated with the inhibition of cancer cell stemness, Biomaterials, 2020, 263, 120330 Kaiqi Long1, Yuwei Liu1, Yafei Li and Weiping Wang*, Self-assembly of trigonal building blocks into nanostructures: molecular design and biomedical applications, Journal of Materials Chemistry B , 2020, 8, 6739--6752 (Emerging Investigator Themed Collection, Invited review) Wen Lv and Weiping Wang*, One-Photon Upconversion-Like Photolysis: A New Strategy to Achieve Long-Wavelength Light-Excitable Photolysis, Synlett, 2020, 31, 1129-1134 (Synpacts, Invited review) Han Han1, Yun Li1, Zhen Peng, Kaiqi Long, Chunli Zheng, Weiping Wang*, Thomas J. Webster*, Liang Ge* A Soluplus/Poloxamer 407-based self-nanoemulsifying drug delivery system for the weakly basic drug carvedilol to improve its bioavailability, Nanomedicine: Nanotechnology, Biology and Medicine, 2020, 27, 102199 Wen Lv, Yafei Li, Feiyang Li, Xin Lan, Yaming Zhang, Lili Du, Qiang Zhao, David L. Phillips, Weiping Wang*, Upconversion-like photolysis of BODIPY-based prodrugs via a one-photon process, Journal of the American Chemical Society, 2019, 141, 44, 17482-17486 Zhixiong Wang, Yaming Zhang, Bing Cao, Zhong Ji, Wanling Luo, Shaodong Zhai, Dandan Zhang, Weiping Wang, Da Xing and Xianglong Hu*, Explosible Nanocapsules Excited by Pulsed Microwave for Efficient Thermoacoustic-Chemo Combination Therapy, Nanoscale, 2019, 11, 1710-1719 Jintong Liu, Ping Du, Tianrui Liu, Bernardino J. Córdova Wong, Weiping Wang, Huangxian Ju and Jianping Lei*, A black phosphorus/manganese dioxide nanoplatform: Oxygen self-supply monitoring, photodynamic therapy enhancement and feedback, Biomaterials, 2019, 192, 179-188 Yafei Li, Yaming Zhang and Weiping Wang*, Phototriggered targeting of nanocarriers for drug delivery, Nano Research, 2018, 11, 5424–5438 (Invited Review) Junjie Li, Yafei Li, Yuheng Wang, Wendong Ke, Weijian Chen, Weiping Wang* and Zhishen Ge*, Polymer prodrug-based nanoreactors activated by tumor acidity for orchestrated oxidation/chemotherapy, Nano Letters, 2017, 17, 6983–6990