王辉 - 华南理工大学 - 分子科学与工程学院

个人简介

2018-今：华南理工大学，华南软物质科学与技术高等研究院，特聘副研究员。研究方向，纳米医学与生物材料 2017-2018年：华东师范大学，生命科学学院，专任副研究员 2014-2017年: 中国人民解放军第二军医大学附属长征医院，博士后研究助理 2011-2014年: 华东师范大学, 生命科学学院，纳米材料与生物医学实验室，博士 2008-2011年: 中国科学技术大学, 化学系，功能膜实验室，硕士 2004-2008年: 安徽大学, 化学与化工学院, 学士

研究领域

1.通过超分子策略构建多维聚合物和纳米材料2.发展纳米药物运输系统用于肿瘤治疗3.发展高分子基因递送系统

近期论文

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1) Wang H, Wang Y, Wang Y, Hu J, Li T, Liu H, Zhang Q, Cheng Y. Self-assembled fluorodendrimers combine the features of lipid and polymeric vectors in gene delivery. Angewandte Chemie International Edition，2015, 54, 11647-11651. 2) Liu H†, Wang H†, Yang W, Cheng Y. Disulfide cross-linked low generation dendrimers with high gene transfection efficacy, low cytotoxicity, and low cost. Journal of the American Chemical Society, 2012, 134, 17680-1768. (†共同第一作者) 3) Wang H, Miao W, Wang F, Cheng Y. A Self-Assembled Coumarin-Anchored Dendrimer for Efficient Gene Delivery and Light-Responsive Drug Delivery. Biomacromolecules, 2018, 19, 2194-2201. 4) Wang H, Chang H, Zhang Q, Cheng Y. Fabrication of Low-Generation Dendrimers into Nanostructures for Efficient and Nontoxic Gene Delivery. Topics in Current Chemistry. 2017, 375, 62. 5) Shen W†, Wang H†, Ling-Hu Y, Lv J, Chang H, Cheng Y. Screening of efficient polymers for siRNA delivery in a library of hydrophobically modified polyethyleneimines. Journal of Materials Chemistry B, 2016, 4, 6468-6474. (†共同第一作者) 6) Shen W, Liu H, Ling-Hu Y, Wang H*, Cheng Y*. Enhanced siRNA delivery of a cyclododecylated dendrimer compared to its linear derivative. Journal of Materials Chemistry B, 2016, 4, 5654-5658. (共同通讯作者) 7) Wang H, Hu J, Cai X, Xiao J, Cheng Y. Self-assembled fluorodendrimers in the co-delivery of fluorinated drugs and therapeutic genes. Polymer Chemistry, 2016, 7, 2319-2322. 8) Wang H, Huang Q, Chang H, Xiao J, Cheng Y. Stimuli-responsive dendrimers in drug delivery. Biomaterials Science, 2016, 4, 375-390. 9) Wang H, Wei H, Huang Q, Liu H, Hu J, Cheng Y, Xiao J. Nucleobase-modified dendrimers as nonviral vectors for efficient and low cytotoxic gene delivery. Colloids and Surfaces B-Biointerfaces, 2015, 136, 1148-1155. 10) Wang H, Shao N, Qiao S, Cheng Y. Host-guest chemistry of dendrimer-cyclodextrin conjugates: selective encapsulations of guests within dendrimer or cyclodextrin cavities revealed by NOE NMR techniques. Journal of Physical Chemistry B, 2012, 116, 11217. 11) Wang H, Wu C, Wu Y, Luo J, Xu T. Cation exchange hybrid membranes based on PVA for alkali recovery through diffusion Dialysis. Journal of Membrane Science, 2011, 376, 233-240. 12) Zheng Z, Hu J, Wang H, Huang J, Yu Y, Zhang Q, Cheng Y. Dynamic Softening or Stiffening a Supramolecular Hydrogel by Ultraviolet or Near-Infrared Light. ACS Applied Materials & Interfaces, 2017, 9, 24511-24517. 13) Chang H, Zhang J, Wang H, Lv J, Cheng Y. A Combination of Guanidyl and Phenyl Groups on a Dendrimer Enables Efficient siRNA and DNA Delivery. Biomacromolecules. 2017, 18, 2371-2378. 14) Liu H, Chang H, Lv J, Jiang C, Li Z, Wang F, Wang H, Wang M, Liu C, Wang X, Shao N, He B, Shen W, Zhang Q, Cheng Y. Screening of efficient siRNA carriers in a library of surface-engineered dendrimers. Scientific Reports, 2016, 6, 25069. 15) Shao N, Wang H, He B, Wang Y, Xiao J, Wang Y, Zhang Q, Li Y, Cheng Y. Hydrogen-bonding dramatically modulates the gene transfection efficacy of surface-engineered dendrimers. Biomaterials Science, 2015, 3 500-508. 16) Wang F, Wang Y, Wang H, Shao N, Chen Y, Cheng Y. Synergistic effect of amino acids modified on dendrimer surface in gene delivery. Biomaterials, 2014, 35, 9187-9198. 17) Chang H, Wang H, Shao N, Wang M, Wang X, Cheng Y. Surface-engineered dendrimers with a diaminododecane core achieve efficient gene transfection and low cytotoxicity. Bioconjugate Chemistry, 2014, 25, 342-350.