个人简介
1946-1950浙江大学化学系,获学士学位
1956-1960前苏联莫斯科大学生物系,获哲学博士学位
1960-今中国科学院生物物理研究所,曾任中国科学院生物物理所副所长、生物大分子国家重点实验室学术委员会主任,现任研究员、生物大分子国家重点实验室名誉主任。
1991年当选为中国科学院学部委员(中国科学院院士)
研究领域
长期从事生物膜的研究工作,并以膜脂-蛋白质相互作用为主线,特别关注细胞内膜系统(线粒体、溶酶体等)对重要细胞生命活动的调控机制
近期论文
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1. Qianqian Chen, Juan Zhang, Kai Zhao, Wei Li, Qi Miao, Yang Sun, Xingyu Zhao, Taotao Wei* and Fuyu Yang*.Lysosomal chymotrypsin inducesmitochondrial fission in apoptotic cellsby proteolytic activation of calcineurin. Protein & Cell 5(2014), 643-647.
2. WenjuanDuan, Juefei Zhou, Wei Li, Teng Zhou, Qianqian Chen, Fuyu Yang* and Taotao Wei*.Plasma membrane calcium ATPase 4binhibits nitric oxide generation throughcalcium-induced dynamic interaction withneuronal nitric oxide synthase. Protein & Cell4(2013), 286-298.
3. Kai Zhao, Hejiang Zhou, Xingyu Zhao, Dennis W. Wolff, YapingTu, Huili Liu,Taotao Wei* and Fuyu Yang*. Phosphatidic acid mediates the targeting of tBid toinduce lysosomal membrane permeabilizationand apoptosis. Journal of Lipid Research 53(2012), 2102-2114.
4. Kai Zhao, Xingyu Zhao, YapingTu, Qi Miao, Dongxu Cao, WenjuanDuan, Yang Sun, Jincheng Wang, Taotao Wei* and Fuyu Yang*. Lysosomal chymotrypsin B potentiates apoptosis via cleavageof Bid. Cellular and Molecular Life Sciences 67(2010), 2665-2678.
5. Qi Miao, Yang Sun, Taotao Wei, Xingyu Zhao, Kai Zhao, Ling Yan, Xujia Zhang, Hongjun Shuand Fuyu Yang*. Chymotrypsin B cached in rat liver lysosomes and involvedin apoptotic regulation through a mitochondrial pathway. The Journalof Biological Chemistry283(2008), 8218-8228. (Highlighted by Nature China)