柳振峰 - 中国科学院生物物理研究所 -

个人简介

1994-1998 厦门大学生物学系生物学专业，获理学学士学位 1998-2004 中国科学院生物物理研究所，获理学博士学位 2004-2010 加州理工学院化学与化工系/霍华德修斯医学研究所，博士后/助理研究员 2011-至今中国科学院生物物理研究所，研究员

研究领域

膜蛋白在细胞活动中承担了各种各样的重要生物学功能，例如光合作用中的光能吸收和转化，呼吸作用中的电子传递和氧化磷酸化，物质的跨膜转运，信号的跨膜转导和膜内的酶促反应（如蛋白质降解，脂的合成和水解等）的催化等等。据估计，原核和真核细胞基因组中大约有20-30%的阅读框编码膜蛋白，凸显膜蛋白研究的重要性

近期论文

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1.Sheng X., Watanabe A., Li A.J., Kim E., Song C.H., Murata K., Song D.F., Minagawa J.* and Liu Z.F.*. Structural insight into light harvesting for photosystem II in green algae. Nat. Plants 5:1320-1330. (2019). （To read the article, please follow the Springer Nature SharedIt link at https://rdcu.be/bYFbR) 2.Jiao H.Z.,Yin Y and Liu Z.F.*. Structures of the Mitochondrial CDP-DAG Synthase Tam41 Suggest a Potential Lipid Substrate Pathway from Membrane to the Active Site. Structure 27, 1258–1269(2019). 3.Liu X. Y., Chai J.C., Ou X. M., Li M. and Liu Z.F.*. Structural Insights into Substrate Selectivity,Catalytic Mechanism, and Redox Regulation of Rice Photosystem II Core Phosphatase. Molecular Plant,1-13, DOI: https://doi.org/10.1016/j.molp.2018.11.006. (2018). 4.Pan X.W., Ma J., Su X.D., Cao P., Chang W. R., Liu Z. F., Zhang X.Z.* and Li M.*. Structure of the maize photosystem I supercomplex with light-harvesting complexes I and II. Science,360:1109-1113 (2018). 5.Sheng X., Liu X. Y., Cao P., Li M and Liu Z.F.*. Structural roles of lipid molecules in the assembly of plant PSII-LHCII supercomplex.Biophys. Rep. 4, 189-203 (2018). 6.Li A.J. and Liu Z.F.*. Supramolecular structural basis of the light-harvesting process in plants. Prog. Biochem. Biophys.（生物化学与生物物理进展） 45, 935-946 (2018). 7.Cao P. ,Su X.D., Pan X.W., Liu Z. F., Chang W. R., and Li M.*. Structure, assembly and energy transfer of plant photosystem II supercomplex. Biochim. Biophys. Acta Bioenergeticcs 1859, 633-644 (2018). 8.Su X.D., Ma J.,Wei X. P., Cao P., Zhu D.J., Chang W. R., Liu Z. F.*, Zhang X.Z.* and Li M.*. Structure and assembly mechanism of plant C2S2M2-type PSII-LHCII supercomplex. Science, 357: 815-820 (2017). 9.Ou X. M., Guo J. L., Wang L. F., Yang H. T., Liu X. Y., Sun J. Y. and Liu Z. F.*. Ion- and water-binding sites inside an occluded hourglass pore of a trimeric intracellular cation (TRIC) channel. BMC Biology 15,31 (2017). 10. Yang H.T., Hu M.H., Guo J.L., Ou X.M., Cai T.X. and Liu Z. F.*. Pore architecture of TRIC channels and insights into their gating mechanism. Nature, 538, 537-541 (2016). 11.Wei X. P., Su X.D.,Cao P., Liu X. Y., Chang W. R., Li M.*, Zhang X.Z.* and Liu Z. F.*. Structure of spinach photosystem II- LHCII supercomplex at 3.2 ？ resolution. Nature, 534, 69-74 (2016). 12. Li J., Guo J. L., Ou X. M., Zhang M. F., Li Y.Z. and Liu Z. F.* (2015). Mechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion. Proc. Natl. Acad. Sci. USA, 112: 10726-10731 (2015). 13.Wei X. P., Guo J. T., Li M.and Liu Z. F.* (2015). Structural Mechanism Underlying the Specific Recognition between the Arabidopsis State-Transition Phosphatase TAP38/PPH1 and Phosphorylated Light-Harvesting Complex Protein Lhcb1. Plant Cell, 27: 1113-1127. (2015, doi: 10.1105/tpc.15.00102). 14. Liu X. Y., Yan Y., Wu J. J. and Liu Z. F.* (2014). Structure and mechanism of an intramembrane liponucleotide synthetase central for phospholipid biosynthesis. Nat. Commun. 5:4244. 15. Pan X. W., Liu Z. F.*, Li M. & Chang W. R.*. (2013) Architecture and function of plant light-harvesting complexes II. Curr. Opin. Struct. Biol. 23:515-525. (* Corresponding authors) 16. Guo J. T., Wei X. P., Li M., Pan X. W., Chang W. R.* & Liu Z. F.* (2013) Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae. Protein & Cell 4, 607-619. (* Corresponding authors) 17. Liu Z.F.，Walton T.A.，Rees D.C. (2010) A reported archaeal mechanosensitive channel is a structural homolog of MarR-like transcriptional regulators. Protein Science 19，808-814. 18. Liu Z.F.，Gandhi C.S.，Rees D.C. (2009) Structure of a tetrameric MscL in an expanded intermediate state. Nature 461，120-124. 19. Liu Z.F.，Chang W.R. (2008) Structure of the light-harvesting complex II. In: Photosynthetic Protein Complexes. Wiley-VCH (Book chapter)Fromme P. ed., 217-242. 20. Liu Z.F.，Chang W.R. (2008) Crystallization Methods of Membrane Proteins: Practical Aspects of Crystallizing Plant Light-Harvesting Complexes. In: Biophysical Techniques in Photosynthesis II. Spinger (Book chapter)Aartsma T. J. and Matysik J. eds. 26，77-96.