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An Extensive Network of TET2-Targeting microRNAs Regulates Malignant Hematopoiesis.
Jijun Cheng, Shangqin Guo, Suning Chen, Stephen Mastriano, Chaochun Liu, Ana D’Alessio, Eriona Hysolli, Yanwen Guo, Hong Yao, Cynthia Megyola, Dan Li, Jun Liu, Wen Pan, Christine Roden, Kartoosh Heydari, Jianjun Chen, In-Hyun Park, Ye Ding, Yi Zhang, and Jun Lu. An Extensive Network of TET2-Targeting microRNAs Regulates Malignant Hematopoiesis. Cell Reports, 5:1-11, 2013
An In Vivo Functional Screen Uncovers miR-150-Mediated Regulation of Hematopoietic Injury Response.
Brian D. Adams, Shangqin Guo, Haitao Bai, Yanwen Guo, Cynthia Megyola, Jijun Cheng, Kartoosh Heydari, Changchun Xiao, E. Premkumar Reddy, and Jun Lu. An In Vivo Functional Screen Uncovers miR-150-Mediated Regulation of Hematopoietic Injury Response. Cell Reports, 2(4):1048-1060, 2012
Non-stochastic reprogramming from a privileged somatic cell state.
Shangqin Guo*, Xiaoyuan Zi, Vince Schultz, Mei Zhong, Jijun Cheng, Sebastian Koochaki, Cynthia M. Megyola, Xinghua Pan, Kartoosh Heydari, Sherman M. Weissman, Patrick G. Gallagher, Diane S. Krause, Rong Fan, and Jun Lu. Non-stochastic reprogramming from a privileged somatic cell state. Cell, 156(4): 649-62, 2014.
Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms.
Shangqin Guo, Haitao Bai, Cynthia Megyola, Stephanie Halene, Diane S. Krause, David T. Scadden and Jun Lu. Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms. PNAS, 2012
MicroRNA expression profiles classify human cancers.
Jun Lu, Gad Getz, Eric A. Miska, Ezequiel A. Alvarez-Saavedra, Justin Lamb, David Peck, Alejandro Sweet-Cordero, Benjamin L. Ebert, Raymond H. Mak, Adolfo A. Ferrando, James R. Downing, Tyler Jacks, H. Robert Horvitz and Todd R. Golub. MicroRNA expression profiles classify human cancers. Nature, 435(7043):834-8, 2005
Scadden and Todd R. Golub. microRNA-mediated control of of cell fate in megakaryocyte-erythrocyte progenitors.
Jun Lu, Shangqin Guo, Benjamin L. Ebert, Hao Zhang, Xiao Peng, Jocelyn Bosco, Jennifer Pretz, Rita Schlanger, Judy H. Wang, Raymond H. Mak, David M. Dombkowski, Frederic I. Preffer, David T. Scadden and Todd R. Golub. microRNA-mediated control of of cell fate in megakaryocyte-erythrocyte progenitors. Developmental Cell, 14(6):843-53, 2008
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.
Zejuan Li, Jun Lu (co-first author), Miao Sun, Shuangli Mi, Hao Zhang, Roger T. Luo, Zhijian Qian, Mary Beth Neilly, Yungui Wang, Jie Jin, Yanming Zhang, Stefan K. Bohlander, Richard Larson, Michelle Le Beau, Michael J. Thirman, Todd R. Golub, Janet D. Rowley, and Jianjun Chen. MicroRNA expression profiles distinguish common translocations in AML. PNAS, 105(40): 15535-40, 2008
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.
Shuangli Mi, Jun Lu (co-first author), Miao Sun, Zejuan Li, Hao Zhang, Mary Beth Neilly, Yungui Wang, Zhijian Qian, Jie Jin, Yanming Zhang, Stefan K. Bohlander, Michelle M. LeBeau, Richard A. Larson, Todd R. Golub, Janet D. Rowley and Jianjun Chen. MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. PNAS, 104(50):19971-6, 2007
MicroRNA miR-125a controls hematopoietic stem cell number.
Guo S, Lu J (co-first), Schlanger R, Zhang H, Wang JY, Fox MC, Purton LE, Fleming HH, Cobb B, Merkenschlager M, Golub TR, Scadden DT, MicroRNA miR-125a controls hematopoietic stem cell number, PNAS, 107(32):14229-34, 2010
Systematic discovery of regulatory motifs in human promoters and 3’ UTRs by comparison of several mammals.
Xiaohui Xie, Jun Lu, E. J. Kulbokas, Todd R. Golub, Vamsi Mootha, Kerstin Lindblad-Toh, Eric S. Lander and Manolis Kellis. Systematic discovery of regulatory motifs in human promoters and 3’ UTRs by comparison of several mammals. Nature, 434 (7031):338-45, 2005
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